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List of works by Richard Brown

A Diverse Panel of Hepatitis C Virus Glycoproteins for Use in Vaccine Research Reveals Extremes of Monoclonal Antibody Neutralization Resistance.

scientific article published on 23 December 2015

A case of hepatitis C virus transmission acquired through sharing a haemodialysis machine.

scientific article published on 15 October 2010

A central hydrophobic E1 region controls the pH range of hepatitis C virus membrane fusion and susceptibility to fusion inhibitors

scientific article published on 13 February 2019

Acute hepatitis C virus infection: a dynamic-and challenging-concept.

scientific article published on 10 November 2010

An alpaca nanobody inhibits hepatitis C virus entry and cell-to-cell transmission

scientific article

Analysis of serine codon conservation reveals diverse phenotypic constraints on hepatitis C virus glycoprotein evolution

scientific article (publication date: 2014)

Cell entry, efficient RNA replication, and production of infectious hepatitis C virus progeny in mouse liver-derived cells.

scientific article published on 18 November 2013

Characterization of hepatitis C virus intra- and intergenotypic chimeras reveals a role of the glycoproteins in virus envelopment

scientific article published on 02 October 2013

Characterization of the hepatitis C virus E2 epitope defined by the broadly neutralizing monoclonal antibody AP33.

scientific article published in March 2006

Clinical course of infection and viral tissue tropism of hepatitis C virus-like nonprimate hepaciviruses in horses

scientific article published on 5 January 2015

Determination of the human antibody response to the epitope defined by the hepatitis C virus-neutralizing monoclonal antibody AP33.

scientific article

Development of a high-throughput pyrosequencing assay for monitoring temporal evolution and resistance associated variant emergence in the Hepatitis C virus protease coding-region.

scientific article published on 22 July 2014

Efficient acute and chronic infection of stem cell-derived hepatocytes by hepatitis C virus

scientific article published on 29 February 2020

Evolutionary dynamics of hepatitis C virus envelope genes during chronic infection.

scientific article published in July 2005

Exacerbation of hepatitis E virus infection during anti-TNFα treatment

scientific article published on 8 November 2016

Flunarizine prevents hepatitis C virus membrane fusion in a genotype-dependent manner by targeting the potential fusion peptide within E1.

scientific article published on 6 August 2015

Functional and immunogenic characterization of diverse HCV glycoprotein E2 variants

scientific article published on 13 November 2018

Genetic Diversity Underlying the Envelope Glycoproteins of Hepatitis C Virus: Structural and Functional Consequences and the Implications for Vaccine Design

scientific article

Hepacivirus NS3/4A Proteases Interfere with MAVS Signaling in both Their Cognate Animal Hosts and Humans: Implications for Zoonotic Transmission

scientific article published on 21 September 2016

Hepatitis C Virus

scientific article published on 29 January 2019

Hepatitis C Virus Strain-Dependent Usage of Apolipoprotein E Modulates Assembly Efficiency and Specific Infectivity of Secreted Virions.

scientific article published on 28 June 2017

Hepatitis C patient-derived glycoproteins exhibit marked differences in susceptibility to serum neutralizing antibodies: genetic subtype defines antigenic but not neutralization serotype.

scientific article

Hepatitis C virus envelope glycoprotein fitness defines virus population composition following transmission to a new host

scientific article

Hepatitis E Virus (HEV) ORF2 Antigen Levels Differentiate Between Acute and Chronic HEV Infection

scientific article published on 27 May 2016

Identification of Conserved Residues in the E2 Envelope Glycoprotein of the Hepatitis C Virus That Are Critical for CD81 Binding

scientific article

Identification of Keratin 23 as a Hepatitis C Virus-Induced Host Factor in the Human Liver

scientific article published on 18 June 2019

Immune protection against reinfection with nonprimate hepacivirus.

scientific article published on 08 March 2017

Immunization with a synthetic consensus hepatitis C virus E2 glycoprotein ectodomain elicits virus-neutralizing antibodies

scientific article published on 11 September 2018

In vivo evidence for ribavirin-induced mutagenesis of the hepatitis E virus genome

scientific article

Incorporation of primary patient-derived glycoproteins into authentic infectious hepatitis C virus particles.

scientific article published on 24 June 2014

Intercompartmental recombination of HIV-1 contributes to env intrahost diversity and modulates viral tropism and sensitivity to entry inhibitors

scientific article

Ion Channel Function and Cross-Species Determinants in Viral Assembly of Nonprimate Hepacivirus p7 ⬇️

scientific article published on 9 March 2016

Liver-expressed Cd302 and Cr1l limit hepatitis C virus cross-species transmission to mice

scientific article published on 04 November 2020

Mannan binding lectin-associated serine protease 1 is induced by hepatitis C virus infection and activates human hepatic stellate cells.

scientific article published on November 2013

Molecular characteristics and successful management of a respiratory syncytial virus outbreak among pediatric patients with hemato-oncological disease.

scientific article published on 13 February 2018

Mutagenic Effects of Ribavirin on Hepatitis E Virus-Viral Extinction versus Selection of Fitness-Enhancing Mutations

scientific article

Natural reservoirs for homologs of hepatitis C virus.

scientific article

Naturally occurring antibodies that recognize linear epitopes in the amino terminus of the hepatitis C virus E2 protein confer noninterfering, additive neutralization

scientific article (publication date: March 2012)

Non-macrophage-tropic human immunodeficiency virus type 1 R5 envelopes predominate in blood, lymph nodes, and semen: implications for transmission and pathogenesis.

scientific article

Recombinant human L-ficolin directly neutralizes hepatitis C virus entry.

scientific article published on 15 May 2014

Targeting a host-cell entry factor barricades antiviral-resistant HCV variants from on-therapy breakthrough in human-liver mice

scientific article published on 25 August 2015

Tracking HCV protease population diversity during transmission and susceptibility of founder populations to antiviral therapy.

scientific article published on 3 January 2017

Variation in HIV-1 R5 macrophage-tropism correlates with sensitivity to reagents that block envelope: CD4 interactions but not with sensitivity to other entry inhibitors.

scientific article published on 18 January 2008

Variation in the biological properties of HIV-1 R5 envelopes: implications of envelope structure, transmission and pathogenesis

scientific article

Vertical transmission of hepatitis C virus-like non-primate hepacivirus in horses

scientific article published on 26 July 2016

Yellow Fever: Integrating Current Knowledge with Technological Innovations to Identify Strategies for Controlling a Re-Emerging Virus

scientific article published on 17 October 2019

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