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List of works by Salvatore Spicuglia

A comprehensive catalog of LncRNAs expressed in T-cell acute lymphoblastic leukemia

scientific article published on 16 January 2019

A critical regulator of Bcl2 revealed by systematic transcript discovery of lncRNAs associated with T-cell differentiation

scientific article published on 18 March 2019

A unique H3K4me2 profile marks tissue-specific gene regulation

scientific article

Active STAT5 regulates T-bet and eomesodermin expression in CD8 T cells and imprints a T-bet-dependent Tc1 program with repressed IL-6/TGF-β1 signaling

scientific article published on 4 September 2013

An early thymic precursor phenotype predicts outcome exclusively in HOXA-overexpressing adult T-cell acute lymphoblastic leukemia: a Group for Research in Adult Acute Lymphoblastic Leukemia study

scientific article published on 04 March 2016

An update on recent methods applied for deciphering the diversity of the noncoding RNA genome structure and function

scientific article published on 15 April 2013

Ascorbic acid drives the differentiation of mesoderm-derived embryonic stem cells. Involvement of p38 MAPK/CREB and SVCT2 transporter.

scientific article published on 13 December 2016

Assessing the efficiency and significance of Methylated DNA Immunoprecipitation (MeDIP) assays in using in vitro methylated genomic DNA

scientific article

Assessing the role of the T cell receptor beta gene enhancer in regulating coding joint formation during V(D)J recombination

scientific article published on 14 March 2003

BLUEPRINT to decode the epigenetic signature written in blood.

scientific article

CD8+ T Cells from Human Neonates Are Biased toward an Innate Immune Response.

scientific article published in November 2016

Candidate luminal B breast cancer genes identified by genome, gene expression and DNA methylation profiling

scientific article published on 09 January 2014

Characterisation of genome-wide PLZF/RARA target genes

scientific article

Characterization of lysine 56 of histone H3 as an acetylation site in Saccharomyces cerevisiae

scientific article

Chromatin remodeling by the T cell receptor (TCR)-beta gene enhancer during early T cell development: Implications for the control of TCR-beta locus recombination

scientific article

Chromatin signatures of active enhancers

scientific article published on March 2012

CoCAS: a ChIP-on-chip analysis suite

scientific article published on 04 February 2009

Control of IL-2Ralpha gene expression: structural changes within the proximal enhancer/core promoter during T-cell development

scientific article published on May 2002

CpG islands and GC content dictate nucleosome depletion in a transcription-independent manner at mammalian promoters

scientific article

Cryptic XPO1-MLLT10 translocation is associated with HOXA locus deregulation in T-ALL.

scientific article published on November 2014

Definition of a T-cell receptor beta gene core enhancer of V(D)J recombination by transgenic mapping.

scientific article

Divergent transcription is associated with promoters of transcriptional regulators

scientific article

Duality of enhancer functioning mode revealed in a reduced TCR beta gene enhancer knockin mouse model

scientific article published in December 2009

Dynamic recruitment of Ets1 to both nucleosome-occupied and -depleted enhancer regions mediates a transcriptional program switch during early T-cell differentiation.

scientific article

Early Response-Based Therapy Stratification Improves Survival in Adult Early Thymic Precursor Acute Lymphoblastic Leukemia: A Group for Research on Adult Acute Lymphoblastic Leukemia Study

scientific article published on 12 June 2017

Epigenetic control of Tcrb gene rearrangement.

scientific article published on 15 September 2010

Epigenetic regulation of antigen receptor gene rearrangement

scientific article

Epromoters function as a hub to recruit key transcription factors required for the inflammatory response

scientific article published on 18 November 2021

Extensive molecular mapping of TCRα/δ- and TCRβ-involved chromosomal translocations reveals distinct mechanisms of oncogene activation in T-ALL.

scientific article published on 4 September 2012

Genome-wide characterization of mammalian promoters with distal enhancer functions

scientific article published on 5 June 2017

H3K4 tri-methylation provides an epigenetic signature of active enhancers

scientific article

High-throughput and quantitative assessment of enhancer activity in mammals by CapStarr-seq.

scientific article

In vivo reinsertion of excised episomes by the V(D)J recombinase: a potential threat to genomic stability

scientific article

Integration of high-throughput reporter assays identify a critical enhancer of the Ikzf1 gene

scientific article published on 26 May 2020

Integrative analysis of public ChIP-seq experiments reveals a complex multi-cell regulatory landscape

scientific article

Molecular genetics at the T-cell receptor beta locus: insights into the regulation of V(D)J recombination.

scientific article published on January 2009

Novel CD28-responsive enhancer activated by CREB/ATF and AP-1 families in the human interleukin-2 receptor alpha-chain locus

scientific article published in July 2001

PcG methylation of the HIST1 cluster defines an epigenetic marker of acute myeloid leukemia

scientific article published on 8 December 2014

Potassium permanganate as a probe to map DNA-protein interactions in vivo

scientific article

Promoter activation by enhancer-dependent and -independent loading of activator and coactivator complexes

scientific article published on December 2002

RUNX1-dependent RAG1 deposition instigates human TCR-δ locus rearrangement

scientific article

RUNX1-dependent RAG1 deposition instigates human TCR-δ locus rearrangement

Recent advances in high-throughput approaches to dissect enhancer function

scientific article

Regulation of V(D)J recombination

scientific article

Reversal of microRNA-150 silencing disadvantages crizotinib-resistant NPM-ALK(+) cell growth

scientific article

TCR beta allelic exclusion in dynamical models of V(D)J recombination based on allele independence

scientific article published on 28 June 2010

TCRalpha enhancer activation occurs via a conformational change of a pre-assembled nucleo-protein complex

scientific article

TCRα rearrangements identify a subgroup of NKL-deregulated adult T-ALLs associated with favorable outcome.

scientific article published on 8 June 2017

TLX homeodomain oncogenes mediate T cell maturation arrest in T-ALL via interaction with ETS1 and suppression of TCRα gene expression

scientific article

Transcription initiation platforms and GTF recruitment at tissue-specific enhancers and promoters.

scientific article

Transcription-dependent generation of a specialized chromatin structure at the TCRβ locus.

scientific article

Transcriptional regulation by promoters with enhancer function

scientific article published on 25 June 2018

Triggering the TCR Developmental Checkpoint Activates a Therapeutically Targetable Tumor Suppressive Pathway in T-cell Leukemia.

scientific article published on 28 June 2016

Uncleaved TFIIA is a substrate for taspase 1 and active in transcription

scientific article

[Alpha/beta versus gamma/delta T cell development: a choice linked to the transcription factor Sox13]

scientific article published on 01 May 2007

[Functions of lncRNA in development and diseases]

scientific article published on 01 August 2014

[Hypermethylation of CpG island in promoter region of MEIS1 gene and its expression in HOX11(+) acute T lymphoblastic leukemia]

[The European Blueprint project: towards a full epigenome characterization of the immune system].

scientific article

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