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List of works by Ulrich Lächelt

Acid-labile pHPMA modification of four-arm oligoaminoamide pDNA polyplexes balances shielding and gene transfer activity in vitro and in vivo.

scientific article

Coordinative Binding of Polymers to Metal-Organic Framework Nanoparticles for Control of Interactions at the Biointerface

scientific article published on 15 March 2019

Delivery of Cas9/sgRNA Ribonucleoprotein Complexes via Hydroxystearyl Oligoamino Amides

scientific article published on 03 February 2020

Dual antitumoral potency of EG5 siRNA nanoplexes armed with cytotoxic bifunctional glutamyl-methotrexate targeting ligand.

scientific article published on 5 November 2015

Dual-targeted polyplexes based on sequence-defined peptide-PEG-oligoamino amides

scientific article published on 29 September 2014

Epidermal growth factor receptor targeted methotrexate and small interfering RNA co-delivery

scientific article published on 17 July 2018

Fine-tuning of proton sponges by precise diaminoethanes and histidines in pDNA polyplexes.

scientific article

From Artificial Amino Acids to Sequence-Defined Targeted Oligoaminoamides

scientific article published on 01 January 2016

Histidine-rich stabilized polyplexes for cMet-directed tumor-targeted gene transfer

scientific article published on March 2015

Lipo-Oligomer Nanoformulations for Targeted Intracellular Protein Delivery.

scientific article published on 26 June 2017

Metal Organic Nanopharmaceuticals

scientific article published on 21 April 2020

Multifunctional Cationic PeptoStars as siRNA Carrier: Influence of Architecture and Histidine Modification on Knockdown Potential

scientific article published on 20 August 2019

Multifunctional Efficiency: Extending the Concept of Atom Economy to Functional Nanomaterials.

scientific article published on 13 March 2018

Multifunctional Nanoparticles by Coordinative Self-Assembly of His-Tagged Units with Metal-Organic Frameworks.

scientific article published on 11 January 2017

Multifunctional Oligoaminoamides for the Receptor-Specific Delivery of Therapeutic RNA

scientific article published on 01 January 2015

Nanosized multifunctional polyplexes for receptor-mediated siRNA delivery

scientific article published on 07 June 2012

Native chemical ligation for conversion of sequence-defined oligomers into targeted pDNA and siRNA carriers.

scientific article

Nucleic Acid Therapeutics Using Polyplexes: A Journey of 50 Years (and Beyond).

scientific article published on 15 April 2015

Sequence-defined nucleic acid carriers combining distinct modules for complexation, shielding, receptor-targeting and endosomal escape

scientific article published on 19 August 2015

Solid-phase-assisted synthesis of targeting peptide-PEG-oligo(ethane amino)amides for receptor-mediated gene delivery

scientific article

Synthetic polyglutamylation of dual-functional MTX ligands for enhanced combined cytotoxicity of poly(I:C) nanoplexes

scientific article

Toward Artificial Immunotoxins: Traceless Reversible Conjugation of RNase A with Receptor Targeting and Endosomal Escape Domains

scientific article

Toxicity of metal–organic framework nanoparticles: from essential analyses to potential applications

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