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List of works by Dirk Holzinger

A subgroup of juvenile idiopathic arthritis patients who respond well to methotrexate are identified by the serum biomarker MRP8/14 protein.

scientific article published on 25 April 2013

Alarming consequences - autoinflammatory disease spectrum due to mutations in proline-serine-threonine phosphatase-interacting protein 1.

scientific article published on September 2016

Alarmins firing arthritis: Helpful diagnostic tools and promising therapeutic targets

scientific article published on 19 September 2016

Alarmins of the S100-Family in Juvenile Autoimmune and Auto-Inflammatory Diseases

scientific article published on 15 February 2019

Elevated S100A8/A9 and S100A12 Serum Levels Reflect Intraocular Inflammation in Juvenile Idiopathic Arthritis-Associated Uveitis: Results From a Pilot Study

scientific article published on December 2015

From synovial tissue to peripheral blood: myeloid related protein 8/14 is a sensitive biomarker for effective treatment in early drug development in patients with rheumatoid arthritis

scientific article

Genetic fever syndromes. Hereditary recurrent (periodic) fever syndromes

scientific article published on May 2013

Genotype-phenotype and genotype-origin correlations in children with mediterranean fever in Germany - an AID-net study

scientific article published on 24 October 2013

HSV-1 viremia as a potential cause of febrile neutropenia in an immunocompromised child.

scientific article published on January 2010

IL-6 amplifies TLR mediated cytokine and chemokine production: implications for the pathogenesis of rheumatic inflammatory diseases

scientific article

Induction of MxA gene expression by influenza A virus requires type I or type III interferon signaling

scientific article published on 09 May 2007

Interleukin-1-mediated diseases ⬇️

scientific article published on April 1, 2013

MRP8 and MRP14, phagocyte-specific danger signals, are sensitive biomarkers of disease activity in cryopyrin-associated periodic syndromes ⬇️

scientific article published on September 8, 2011

MRP8/14 serum levels as a strong predictor of response to biological treatments in patients with rheumatoid arthritis.

scientific article

Methotrexate in the therapy of juvenile idiopathic arthritis

scientific article published on August 2010

Octacalcium phosphate crystals induce inflammation in vivo through interleukin‐1 but independent of the NLRP3 inflammasome in mice ⬇️

scientific article published on February 1, 2011

Periodic fever, aphthous stomatitis, pharyngitis, cervical adenitis syndrome is linked to dysregulated monocyte IL-1β production ⬇️

scientific article published on September 21, 2012

Phagocyte-derived S100 proteins in autoinflammation: putative role in pathogenesis and usefulness as biomarkers.

scientific article published on 07 December 2012

Phagocyte-specific S100 proteins and high-sensitivity C reactive protein as biomarkers for a risk-adapted treatment to maintain remission in juvenile idiopathic arthritis: a comparative study

scientific article published on 11 June 2012

Practice and consensus-based strategies in diagnosing and managing systemic juvenile idiopathic arthritis in Germany

scientific article

Rapid and simple detection of IFN-neutralizing antibodies in chronic hepatitis C non-responsive to IFN-α

article

Review of biomarkers in systemic juvenile idiopathic arthritis: helpful tools or just playing tricks?

scientific article published on 13 July 2016

Role of proteinase-activated receptor-2 in anti-bacterial and immunomodulatory effects of interferon-γ on human neutrophils and monocytes

scientific article

S100A12 as diagnostic tool in the differential diagnosis of sJIA associated MAS vs. hereditary or acquired HLH.

scientific article published on 28 September 2015

Single amino acid charge switch defines clinically distinct proline-serine-threonine phosphatase-interacting protein 1 (PSTPIP1)-associated inflammatory diseases

scientific article published on 26 May 2015

Staphylococcus aureus Panton-Valentine leukocidin induces an inflammatory response in human phagocytes via the NLRP3 inflammasome

scientific article

Staphylococcus aureus panton-valentine leukocidin is a very potent cytotoxic factor for human neutrophils

scientific article

Staphylococcus aureus phenotype switching: an effective bacterial strategy to escape host immune response and establish a chronic infection

scientific article

Subcutaneous infection with S. aureus in mice reveals association of resistance with influx of neutrophils and Th2 response

scientific article published on 30 September 2010

The German version of the Juvenile Arthritis Multidimensional Assessment Report (JAMAR).

scientific article published on 7 April 2018

The Toll-like receptor 4 agonist MRP8/14 protein complex is a sensitive indicator for disease activity and predicts relapses in systemic-onset juvenile idiopathic arthritis.

scientific article published on 20 January 2012

The danger from within: alarmins in arthritis

scientific article

Translational research network and patient registry for auto-inflammatory diseases ⬇️

scientific article published on January 1, 2011

Treatment to Target Using Recombinant Interleukin-1 Receptor Antagonist as First-Line Monotherapy in New-Onset Systemic Juvenile Idiopathic Arthritis: Results From a Five-Year Follow-Up Study

scientific article published on 25 May 2019

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