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List of works by Geraldine Seydoux

'Goldilocks' suppressor screen identifies web of polarity regulators ⬇️

scientific article published on January 1, 2013

3' UTRs are the primary regulators of gene expression in the C. elegans germline

scientific article published on 25 September 2008

A clean start: degradation of maternal proteins at the oocyte-to-embryo transition

scientific article published in August 2004

A gel phase promotes condensation of liquid P granules in Caenorhabditis elegans embryos

scientific article published on 04 March 2019

Analysis of gain-of-function mutations of the lin-12 gene of Caenorhabditis elegans

scientific article published in July 1990

Anterior-posterior polarity in C. elegans and Drosophila--PARallels and differences

scientific article

Asymmetric segregation of PIE-1 in C. elegans is mediated by two complementary mechanisms that act through separate PIE-1 protein domains

scientific article published in August 2000

Author Correction: A gel phase promotes condensation of liquid P granules in Caenorhabditis elegans embryos

scientific article published on 01 February 2020

Cas9-assisted recombineering in C. elegans: genome editing using in vivo assembly of linear DNAs.

scientific article published on June 2016

Cell autonomy of lin-12 function in a cell fate decision in C. elegans.

scientific article

Cell-cell interactions prevent a potential inductive interaction between soma and germline in C. elegans

scientific article

Conserved regulation of MAP kinase expression by PUF RNA-binding proteins

scientific article

Coordinate activation of maternal protein degradation during the egg-to-embryo transition in C. elegans

scientific article published in September 2003

Cytoplasmic partitioning of P granule components is not required to specify the germline in C. elegans

scientific article

Dedifferentiation of primary spermatocytes into germ cell tumors in C. elegans lacking the pumilio-like protein PUF-8.

scientific article published in January 2003

Dynamics of mRNA entry into stress granules

scientific article published on 01 February 2019

Embryo emergent: elucidating the cell biology of development. The Santa Cruz Conference on Developmental Biology 2000.

scientific article published on December 2000

Exclusion of germ plasm proteins from somatic lineages by cullin-dependent degradation

scientific article

Genetic requirements for PIE-1 localization and inhibition of gene expression in the embryonic germ lineage of Caenorhabditis elegans

scientific article

Germ cell specification

scientific article published on January 2013

High Efficiency, Homology-Directed Genome Editing in Caenorhabditis elegans Using CRISPR-Cas9 Ribonucleoprotein Complexes.

scientific article

Identification of suppressors of mbk-2/DYRK by whole-genome sequencing

scientific article published on 19 February 2014

Inhibition of transcription by the Caenorhabditis elegans germline protein PIE-1: genetic evidence for distinct mechanisms targeting initiation and elongation

scientific article

Interaction between ran1+ protein kinase and cAMP dependent protein kinase as negative regulators of fission yeast meiosis ⬇️

scientific article published on December 1, 1991

Lattice light-sheet microscopy: imaging molecules to embryos at high spatiotemporal resolution

scientific article

Launching the germline in Caenorhabditis elegans: regulation of gene expression in early germ cells.

scientific article

Less is more: specification of the germline by transcriptional repression

scientific article published on December 2008

Loss-of-function genetic tools for animal models: cross-species and cross-platform differences

scientific article published on 31 October 2016

MIP-MAP: High Throughput Mapping of Caenorhabditis elegans Temperature-Sensitive Mutants via Molecular Inversion Probes.

scientific article

Metaphase to anaphase (mat) transition-defective mutants in Caenorhabditis elegans

scientific article

Microtubules induce self-organization of polarized PAR domains in Caenorhabditis elegans zygotes

scientific journal article

Nanos promotes epigenetic reprograming of the germline by down-regulation of the THAP transcription factor LIN-15B.

scientific article published on 7 November 2017

Not just Salk

scientific article published in September 2017

P Granules Protect RNA Interference Genes from Silencing by piRNAs

scientific article published on 08 August 2019

P granules

scientific article published on July 2014

PIE-1 is a bifunctional protein that regulates maternal and zygotic gene expression in the embryonic germ line of Caenorhabditis elegans

scientific article

Pathway to totipotency: lessons from germ cells

scientific article

Phase Separation in Biology and Disease

scientific article published on 11 September 2018

Phase separation in biology and disease-a symposium report

scientific article published on 14 June 2019

Polarization of the C. elegans zygote proceeds via distinct establishment and maintenance phases ⬇️

scientific article published on April 2003

Polarization of the anterior-posterior axis of C. elegans is a microtubule-directed process

scientific article published in November 2000

Precision genome editing using CRISPR-Cas9 and linear repair templates in C. elegans.

scientific article published on 6 April 2017

Precision genome editing using synthesis-dependent repair of Cas9-induced DNA breaks

scientific article published on 28 November 2017

Processing bodies and germ granules are distinct RNA granules that interact in C. elegans embryos

scientific article published on 16 July 2008

Puromycin reactivity does not accurately localize translation at the subcellular level

scientific article published on 26 August 2020

RNA granules in germ cells

scientific article published on December 2011

Rapid Tagging of Human Proteins with Fluorescent Reporters by Genome Engineering using Double-Stranded DNA Donors

scientific article published on 01 December 2019

Recruitment of mRNAs to P granules by condensation with intrinsically-disordered proteins

scientific article published on 24 January 2020

Regulation of MBK-2/DYRK by CDK-1 and the pseudophosphatases EGG-4 and EGG-5 during the oocyte-to-embryo transition

scientific article

Regulation of MBK-2/Dyrk kinase by dynamic cortical anchoring during the oocyte-to-zygote transition

scientific article published in September 2007

Regulation of RNA granule dynamics by phosphorylation of serine-rich, intrinsically disordered proteins in C. elegans

scientific article

Regulation of the MEX-5 gradient by a spatially segregated kinase/phosphatase cycle

scientific article

Regulation of the oocyte-to-zygote transition

scientific article published on April 2007

Repression of gene expression in the embryonic germ lineage of C. elegans

scientific article published in August 1996

Revisiting the role of microtubules in C. elegans polarity

scientific article

Scalable and versatile genome editing using linear DNAs with microhomology to Cas9 Sites in Caenorhabditis elegans

scientific article

Single-molecule study reveals the frenetic lives of proteins in gradients.

scientific article published on 4 September 2018

Soma-germline asymmetry in the distributions of embryonic RNAs in Caenorhabditis elegans

scientific article published in October 1994

Spatial patterning of P granules by RNA-induced phase separation of the intrinsically-disordered protein MEG-3

scientific article published on 03 December 2016

Spatial regulation of the polarity kinase PAR-1 by parallel inhibitory mechanisms

scientific article published on 25 March 2019

Specification of the germline by Nanos-dependent down-regulation of the somatic synMuvB transcription factor LIN-15B

Spindle dynamics and the role of gamma-tubulin in early Caenorhabditis elegans embryos

scientific article

Stabilization of cell polarity by the C. elegans RING protein PAR-2.

scientific article

Surfing the actomyosin wave: polarization of the C. elegans zygote

scientific article published in September 2004

Symmetry breaking and polarization of the C. elegans zygote by the polarity protein PAR-2

scientific article

The 2006 Genetics Society of America Medal. Victor Ambros

scientific article

The C. elegans DYRK Kinase MBK-2 Marks Oocyte Proteins for Degradation in Response to Meiotic Maturation

scientific article published on 15 December 2005

The C. elegans homolog of nucleoporin Nup98 is required for the integrity and function of germline P granules

scientific article

The P Granules of C. elegans: A Genetic Model for the Study of RNA-Protein Condensates

scientific article published on 08 August 2018

The P granule component PGL-1 promotes the localization and silencing activity of the PUF protein FBF-2 in germline stem cells ⬇️

scientific article published on October 1, 2012

The PAR network: redundancy and robustness in a symmetry-breaking system

scientific article

The Puf RNA-binding proteins FBF-1 and FBF-2 inhibit the expression of synaptonemal complex proteins in germline stem cells

scientific article

The germline in C. elegans: origins, proliferation, and silencing

scientific article

Toti“potent” repressors

scientific article published on 01 September 2006

Transcriptional repression by the Caenorhabditis elegans germ-line protein PIE-1.

scientific article

Transcriptionally repressed germ cells lack a subpopulation of phosphorylated RNA polymerase II in early embryos of Caenorhabditis elegans and Drosophila melanogaster.

scientific article published in June 1997

Transgenic solutions for the germline

scientific article published on 08 February 2010

Translational repression restricts expression of the C. elegans Nanos homolog NOS-2 to the embryonic germline

scientific article published on 24 February 2006

cdk-7 Is required for mRNA transcription and cell cycle progression in Caenorhabditis elegans embryos

scientific article

nos-1 and nos-2, two genes related to Drosophila nanos, regulate primordial germ cell development and survival in Caenorhabditis elegans

scientific article published in November 1999

unc-3, a gene required for axonal guidance in Caenorhabditis elegans, encodes a member of the O/E family of transcription factors.

scientific article

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