List of works - Gloria Alvarez-Llamas

2017 update on the relationship between diabetes and colorectal cancer: epidemiology, potential molecular mechanisms and therapeutic implications

scientific article

30μm spatial resolution protein MALDI MSI: In-depth comparison of five sample preparation protocols applied to human healthy and atherosclerotic arteries.

scientific article

8D.08: MATRIX METALLOPROTEINASE (MMP) 2 AND MMP9 ACTIVITY IS INCREASED IN CONDITIONS OF ALBUMINURIA ESCAPE UNDER CHRONIC RENIN-ANGIOTENSIN SYSTEM SUPPRESSION.

scientific article published in June 2015

A comprehensive study of calcific aortic stenosis: from rabbit to human samples.

scientific article

A multicentric study to evaluate the use of relative retention times in targeted proteomics.

scientific article published on 29 October 2016

A novel methodology for the analysis of membrane and cytosolic sub-proteomes of erythrocytes by 2-DE.

scientific article

A proteomic focus on the alterations occurring at the human atherosclerotic coronary intima.

scientific article

A role for the membrane proteome in human chronic kidney disease erythrocytes

scientific article published on 17 July 2012

Advances in understanding the role of angiotensin-regulated proteins in kidney diseases

An optimum method designed for 2-D DIGE analysis of human arterial intima and media layers isolated by laser microdissection

scientific article

Analyses of intricate kinetics of the serum proteome during and after colon surgery by protein expression time series

scientific article

Analysis of the plasma proteome associated with acute coronary syndrome: does a permanent protein signature exist in the plasma of ACS patients?

scientific article

Analysis of urinary exosomal metabolites identifies cardiovascular risk signatures with added value to urine analysis

scientific article published on 14 December 2020

Application of Metabolomics to Cardiovascular and Renal Disease Biomarker Discovery

Association between renal dysfunction and metalloproteinase (MMP)-9 activity in hypertensive patients

scientific article published on 01 December 2018

Author Correction: Immune system deregulation in hypertensive patients chronically RAS suppressed developing albuminuria.

scientific article published on 2 March 2018

Cardiovascular risk study in patients with renin-angiotensin system blockade by means of the proteone of circulating extracellular vesicles

scientific article published on 19 September 2015

Characterization and analysis of human arterial tissue secretome by 2-DE and nLC-MS/MS.

scientific article published in January 2013

Characterization of membrane and cytosolic proteins of erythrocytes

scientific article published in January 2013

Characterization of the human visceral adipose tissue secretome

scientific article

Citric Acid Metabolism in Resistant Hypertension: Underlying Mechanisms and Metabolic Prediction of Treatment Response

scientific article

Colon cancer modulation by a diabetic environment: A single institutional experience

scientific article

Corrigendum to “Novel liquid chromatography–mass spectrometry method for sensitive determination of the mustard allergen Sin a 1 in food” [Food Chem. 183 (2015) 58–63]

scientific article published on 01 September 2016

Cytoskeleton deregulation and impairment in amino acids and energy metabolism in early atherosclerosis at aortic tissue with reflection in plasma

scientific article published on 7 December 2015

Deregulation of smooth muscle cell cytoskeleton within the human atherosclerotic coronary media layer.

scientific article

Development of an optimal protocol for the proteomic analysis of stenotic and healthy aortic valves

scientific article published in January 2010

Diabetes-mediated promotion of colon mucosa carcinogenesis is associated with mitochondrial dysfunction

scientific article published on 27 July 2019

Diabetic nephropathy induces changes in the proteome of human urinary exosomes as revealed by label-free comparative analysis

scientific article published on 7 November 2013

Differential analysis of protein expression of Bifidobacterium grown on different carbohydrates

scientific article

Differential metabolic profile associated with the condition of normoalbuminuria in the hypertensive population

scientific article published on 03 March 2020

Endothelial Regulator of Calcineurin 1 Promotes Barrier Integrity and Modulates Histamine-Induced Barrier Dysfunction in Anaphylaxis.

scientific article published on 20 October 2017

Erratum to: KLK1 and ZG16B proteins and arginine–proline metabolism identified as novel targets to monitor atherosclerosis, acute coronary syndrome and recovery

scholarly article published in Metabolomics

Exosomes: a potential key target in cardio-renal syndrome

scientific article

Hypertensive patients exhibit an altered metabolism. A specific metabolite signature in urine is able to predict albuminuria progression

scientific article published on 15 July 2016

Identification of a urine metabolomic signature in patients with advanced-stage chronic kidney disease

scientific article published on 18 September 2013

Identification of six cardiovascular risk biomarkers in the young population: A promising tool for early prevention

scientific article published on 14 January 2019

Immune system deregulation in hypertensive patients chronically RAS suppressed developing albuminuria.

scientific article published on 21 August 2017

KLK1 and ZG16B proteins and arginine-proline metabolism identified as novel targets to monitor atherosclerosis, acute coronary syndrome and recovery

scientific article

Kalirin and CHD7: novel endothelial dysfunction indicators in circulating extracellular vesicles from hypertensive patients with albuminuria

scientific article published on February 2017

Kidney tissue proteomics reveals regucalcin downregulation in response to diabetic nephropathy with reflection in urinary exosomes

scientific article

Laser microdissection and saturation labeling DIGE method for the analysis of human arteries.

scientific article

Lifetime cardiovascular risk is associated with a multimarker score of systemic oxidative status in young adults independently of traditional risk factors

scientific article published on 29 June 2019

Lipid and protein maps defining arterial layers in atherosclerotic aorta.

scientific article published on 24 June 2015

Metabolomic profiling for identification of novel potential biomarkers in cardiovascular diseases.

scientific article

Modification of the secretion pattern of proteases, inflammatory mediators, and extracellular matrix proteins by human aortic valve is key in severe aortic stenosis

scientific article published on 23 May 2013

Molecular anatomy of ascending aorta in atherosclerosis by MS Imaging: Specific lipid and protein patterns reflect pathology.

scientific article published on 12 June 2015

Molecular evidence of field cancerization initiated by diabetes in colon cancer patients

scientific article published on 16 February 2019

Molecular histology of arteries: mass spectrometry imaging as a novel ex vivo tool to investigate atherosclerosis.

scientific article

Novel liquid chromatography-mass spectrometry method for sensitive determination of the mustard allergen Sin a 1 in food

scientific article published on 12 March 2015

Novel molecular plasma signatures on cardiovascular disease can stratify patients throughout life

scientific article published on 07 May 2020

Osteoprotegerin in exosome-like vesicles from human cultured tubular cells and urine

scientific article

Oxidized Low-Density Lipoprotein Associates with Ventricular Stress in Young Adults and Triggers Intracellular Ca<sup>2+</sup> Alterations in Adult Ventricular Cardiomyocytes

scientific article published on 01 December 2020

Patients with calcific aortic stenosis exhibit systemic molecular evidence of ischemia, enhanced coagulation, oxidative stress and impaired cholesterol transport

scientific article published on 26 September 2016

Pharmacoproteomics in cardiac hypertrophy and atherosclerosis.

scientific article published on June 2009

Plasma Molecular Signatures in Hypertensive Patients With Renin-Angiotensin System Suppression: New Predictors of Renal Damage and De Novo Albuminuria Indicators

scientific article

Plasma metabolomics reveals a potential panel of biomarkers for early diagnosis in acute coronary syndrome

scientific article

Potential role of new molecular plasma signatures on cardiovascular risk stratification in asymptomatic individuals.

scientific article published on 19 March 2018

Prediction of development and maintenance of high albuminuria during chronic renin-angiotensin suppression by plasma proteomics

scientific article published on 29 May 2015

Prediction of the early response to spironolactone in resistant hypertension by the combination of matrix metalloproteinase-9 activity and arterial stiffness parameters

scientific article published on 14 July 2020

Proteomic Analysis of Blood Extracellular Vesicles in Cardiovascular Disease by LC-MS/MS Analysis

scientific article published in January 2017

Proteomic analysis of urinary exosomes in cardiovascular and associated kidney diseases by two-dimensional electrophoresis and LC-MS/MS.

scientific article published in January 2013

Proteomics analysis of Hodgkin lymphoma: identification of new players involved in the cross-talk between HRS cells and infiltrating lymphocytes

scientific article published on 10 December 2007

Proteomics profiling of urine with surface enhanced laser desorption/ionization time of flight mass spectrometry

scientific article

Rapid, Automated, and Specific Immunoassay to Directly Measure Matrix Metalloproteinase-9-Tissue Inhibitor of Metalloproteinase-1 Interactions in Human Plasma Using AlphaLISA Technology: A New Alternative to Classical ELISA

scientific article published on 24 July 2017

Recent advances in atherosclerosis-based proteomics: new biomarkers and a future perspective.

scientific article published on October 2008

Sample Stability and Protein Composition of Saliva: Implications for Its Use as a Diagnostic Fluid

scientific article

Secretome analysis of atherosclerotic and non-atherosclerotic arteries reveals dynamic extracellular remodeling during pathogenesis

scientific article published on 16 December 2011

Secretome of human aortic valves

scientific article published in January 2013

The Authors Reply:

scientific article published on 01 May 2014

Tissue proteomics in atherosclerosis: elucidating the molecular mechanisms of cardiovascular diseases.

scientific article published on August 2009

Translational science in albuminuria: a new view of de novo albuminuria under chronic RAS suppression

scientific article published on 06 April 2018

Two-Dimensional Electrophoresis and Identification by Mass Spectrometry.

scientific article published in January 2017

Urinary Kininogen-1 and Retinol binding protein-4 respond to Acute Kidney Injury: predictors of patient prognosis?

scientific article published on 21 January 2016

Urinary alpha-1 antitrypsin and CD59 glycoprotein predict albuminuria development in hypertensive patients under chronic renin-angiotensin system suppression

scientific article

Urinary exosomes reveal protein signatures in hypertensive patients with albuminuria

scientific article

Urinary metabolic signatures reflect cardiovascular risk in the young, middle-aged, and elderly populations

scientific article published on 11 September 2020

Urine 2DE proteome analysis in healthy condition and kidney disease

scientific article published on 14 August 2014

Urine Haptoglobin and Haptoglobin-Related Protein Predict Response to Spironolactone in Patients With Resistant Hypertension

scientific article published on 01 April 2019

Urine metabolomics insight into acute kidney injury point to oxidative stress disruptions in energy generation and H2S availability

scientific article published on 4 October 2017

Valvular aortic stenosis: a proteomic insight

scientific article

Vascular proteomics.

scientific article published on September 2007

Vascular proteomics.

scientific article published on January 2013

List of works by Gloria Alvarez-Llamas

2017 update on the relationship between diabetes and colorectal cancer: epidemiology, potential molecular mechanisms and therapeutic implications

30μm spatial resolution protein MALDI MSI: In-depth comparison of five sample preparation protocols applied to human healthy and atherosclerotic arteries.

8D.08: MATRIX METALLOPROTEINASE (MMP) 2 AND MMP9 ACTIVITY IS INCREASED IN CONDITIONS OF ALBUMINURIA ESCAPE UNDER CHRONIC RENIN-ANGIOTENSIN SYSTEM SUPPRESSION.

A comprehensive study of calcific aortic stenosis: from rabbit to human samples.

A multicentric study to evaluate the use of relative retention times in targeted proteomics.

A novel methodology for the analysis of membrane and cytosolic sub-proteomes of erythrocytes by 2-DE.

A proteomic focus on the alterations occurring at the human atherosclerotic coronary intima.

A role for the membrane proteome in human chronic kidney disease erythrocytes

Advances in understanding the role of angiotensin-regulated proteins in kidney diseases

An optimum method designed for 2-D DIGE analysis of human arterial intima and media layers isolated by laser microdissection

Analyses of intricate kinetics of the serum proteome during and after colon surgery by protein expression time series

Analysis of the plasma proteome associated with acute coronary syndrome: does a permanent protein signature exist in the plasma of ACS patients?

Analysis of urinary exosomal metabolites identifies cardiovascular risk signatures with added value to urine analysis

Application of Metabolomics to Cardiovascular and Renal Disease Biomarker Discovery

Association between renal dysfunction and metalloproteinase (MMP)-9 activity in hypertensive patients

Author Correction: Immune system deregulation in hypertensive patients chronically RAS suppressed developing albuminuria.

Cardiovascular risk study in patients with renin-angiotensin system blockade by means of the proteone of circulating extracellular vesicles

Characterization and analysis of human arterial tissue secretome by 2-DE and nLC-MS/MS.

Characterization of membrane and cytosolic proteins of erythrocytes

Characterization of the human visceral adipose tissue secretome

Citric Acid Metabolism in Resistant Hypertension: Underlying Mechanisms and Metabolic Prediction of Treatment Response

Colon cancer modulation by a diabetic environment: A single institutional experience

Corrigendum to “Novel liquid chromatography–mass spectrometry method for sensitive determination of the mustard allergen Sin a 1 in food” [Food Chem. 183 (2015) 58–63]

Cytoskeleton deregulation and impairment in amino acids and energy metabolism in early atherosclerosis at aortic tissue with reflection in plasma

Deregulation of smooth muscle cell cytoskeleton within the human atherosclerotic coronary media layer.

Development of an optimal protocol for the proteomic analysis of stenotic and healthy aortic valves

Diabetes-mediated promotion of colon mucosa carcinogenesis is associated with mitochondrial dysfunction

Diabetic nephropathy induces changes in the proteome of human urinary exosomes as revealed by label-free comparative analysis

Differential analysis of protein expression of Bifidobacterium grown on different carbohydrates

Differential metabolic profile associated with the condition of normoalbuminuria in the hypertensive population

Endothelial Regulator of Calcineurin 1 Promotes Barrier Integrity and Modulates Histamine-Induced Barrier Dysfunction in Anaphylaxis.

Erratum to: KLK1 and ZG16B proteins and arginine–proline metabolism identified as novel targets to monitor atherosclerosis, acute coronary syndrome and recovery

Exosomes: a potential key target in cardio-renal syndrome

Hypertensive patients exhibit an altered metabolism. A specific metabolite signature in urine is able to predict albuminuria progression

Identification of a urine metabolomic signature in patients with advanced-stage chronic kidney disease

Identification of six cardiovascular risk biomarkers in the young population: A promising tool for early prevention

Immune system deregulation in hypertensive patients chronically RAS suppressed developing albuminuria.

KLK1 and ZG16B proteins and arginine-proline metabolism identified as novel targets to monitor atherosclerosis, acute coronary syndrome and recovery

Kalirin and CHD7: novel endothelial dysfunction indicators in circulating extracellular vesicles from hypertensive patients with albuminuria

Kidney tissue proteomics reveals regucalcin downregulation in response to diabetic nephropathy with reflection in urinary exosomes

Laser microdissection and saturation labeling DIGE method for the analysis of human arteries.

Lifetime cardiovascular risk is associated with a multimarker score of systemic oxidative status in young adults independently of traditional risk factors

Lipid and protein maps defining arterial layers in atherosclerotic aorta.

Metabolomic profiling for identification of novel potential biomarkers in cardiovascular diseases.

Modification of the secretion pattern of proteases, inflammatory mediators, and extracellular matrix proteins by human aortic valve is key in severe aortic stenosis

Molecular anatomy of ascending aorta in atherosclerosis by MS Imaging: Specific lipid and protein patterns reflect pathology.

Molecular evidence of field cancerization initiated by diabetes in colon cancer patients

Molecular histology of arteries: mass spectrometry imaging as a novel ex vivo tool to investigate atherosclerosis.

Novel liquid chromatography-mass spectrometry method for sensitive determination of the mustard allergen Sin a 1 in food

Novel molecular plasma signatures on cardiovascular disease can stratify patients throughout life

Osteoprotegerin in exosome-like vesicles from human cultured tubular cells and urine

Oxidized Low-Density Lipoprotein Associates with Ventricular Stress in Young Adults and Triggers Intracellular Ca<sup>2+</sup> Alterations in Adult Ventricular Cardiomyocytes

Patients with calcific aortic stenosis exhibit systemic molecular evidence of ischemia, enhanced coagulation, oxidative stress and impaired cholesterol transport

Pharmacoproteomics in cardiac hypertrophy and atherosclerosis.

Plasma Molecular Signatures in Hypertensive Patients With Renin-Angiotensin System Suppression: New Predictors of Renal Damage and De Novo Albuminuria Indicators

Plasma metabolomics reveals a potential panel of biomarkers for early diagnosis in acute coronary syndrome

Potential role of new molecular plasma signatures on cardiovascular risk stratification in asymptomatic individuals.

Prediction of development and maintenance of high albuminuria during chronic renin-angiotensin suppression by plasma proteomics

Prediction of the early response to spironolactone in resistant hypertension by the combination of matrix metalloproteinase-9 activity and arterial stiffness parameters

Proteomic Analysis of Blood Extracellular Vesicles in Cardiovascular Disease by LC-MS/MS Analysis

Proteomic analysis of urinary exosomes in cardiovascular and associated kidney diseases by two-dimensional electrophoresis and LC-MS/MS.

Proteomics analysis of Hodgkin lymphoma: identification of new players involved in the cross-talk between HRS cells and infiltrating lymphocytes

Proteomics profiling of urine with surface enhanced laser desorption/ionization time of flight mass spectrometry

Rapid, Automated, and Specific Immunoassay to Directly Measure Matrix Metalloproteinase-9-Tissue Inhibitor of Metalloproteinase-1 Interactions in Human Plasma Using AlphaLISA Technology: A New Alternative to Classical ELISA

Recent advances in atherosclerosis-based proteomics: new biomarkers and a future perspective.

Sample Stability and Protein Composition of Saliva: Implications for Its Use as a Diagnostic Fluid

Secretome analysis of atherosclerotic and non-atherosclerotic arteries reveals dynamic extracellular remodeling during pathogenesis

Secretome of human aortic valves

The Authors Reply:

Tissue proteomics in atherosclerosis: elucidating the molecular mechanisms of cardiovascular diseases.

Translational science in albuminuria: a new view of de novo albuminuria under chronic RAS suppression

Two-Dimensional Electrophoresis and Identification by Mass Spectrometry.

Urinary Kininogen-1 and Retinol binding protein-4 respond to Acute Kidney Injury: predictors of patient prognosis?

Urinary alpha-1 antitrypsin and CD59 glycoprotein predict albuminuria development in hypertensive patients under chronic renin-angiotensin system suppression

Urinary exosomes reveal protein signatures in hypertensive patients with albuminuria

Urinary metabolic signatures reflect cardiovascular risk in the young, middle-aged, and elderly populations

Urine 2DE proteome analysis in healthy condition and kidney disease

Urine Haptoglobin and Haptoglobin-Related Protein Predict Response to Spironolactone in Patients With Resistant Hypertension

Urine metabolomics insight into acute kidney injury point to oxidative stress disruptions in energy generation and H2S availability