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List of works by Yannis Dotsikas

A GC-MS method for the determination of furanylfentanyl and ocfentanil in whole blood with full validation

scientific article published on 22 October 2018

Achievements in robotic automation of solvent extraction and related approaches for bioanalysis of pharmaceuticals

scientific article published on 19 June 2018

An improved and fully validated LC-MS/MS method for the simultaneous quantification of simvastatin and simvastatin acid in human plasma

scientific article

An improved high-throughput liquid chromatographic/tandem mass spectrometric method for terbinafine quantification in human plasma, using automated liquid-liquid extraction based on 96-well format plates

scientific article

Analysis of potential genotoxic impurities in rabeprazole active pharmaceutical ingredient via Liquid Chromatography-tandem Mass Spectrometry, following quality-by-design principles for method development.

scientific article published on 12 November 2017

Application of a semi-automated 96-well format solid-phase extraction, column-switching, fluorescence detection protocol for the determination of alendronate in human urine samples obtained from a bioequivalence study

scientific article published on 11 October 2006

Application of avidin-biotin technology for the characterization of a model hapten-protein conjugate.

scientific article

Baseline Correction for HPLC Chromatograms by Using Free Open-Source Software

scientific article published in 2023

Birth weight related blood concentrations of the neurotransmission amino acids glutamine plus glutamate, phenylalanine and tyrosine in full-term breastfed infants perinatally

scientific article published on 01 March 2020

Birth weight related essential, non-essential and conditionally essential amino acid blood concentrations in 12,000 breastfed full-term infants perinatally

scientific article published on 14 September 2020

Characterization of the molecular spectrum of Medium-Chain Acyl-CoA Dehydrogenase Deficiency in a Greek newborns cohort: Identification of a novel variant ⬇️

scientific article published on June 6, 2012

Chemometrically assisted development and validation of LC-MS/MS method for the analysis of potential genotoxic impurities in meropenem active pharmaceutical ingredient

scientific article published on 29 June 2017

Classical galactosemia patients can achieve high IQ scores

scientific article published on 01 April 2019

Clinical diagnostic Next-Generation sequencing: the case of CFTR carrier screening.

scientific article published on 15 April 2015

Clinical validation of cutoff target ranges in newborn screening of metabolic disorders by tandem mass spectrometry: a worldwide collaborative project

scientific article published in March 2011

Comparative In Vitro Controlled Release Studies on the Chronobiotic Hormone Melatonin from Cyclodextrins-Containing Matrices and Cyclodextrin: Melatonin Complexes.

scientific article published on 28 July 2017

Comparison of hydrophilic interaction and reversed-phase liquid chromatography coupled with tandem mass spectrometric detection for the determination of three pharmaceuticals in human plasma

scientific article

Development and validation of a rapid 96-well format based liquid-liquid extraction and liquid chromatography-tandem mass spectrometry analysis method for ondansetron in human plasma

scientific article published on 11 April 2006

Development and validation of an improved high-throughput method for the determination of anastrozole in human plasma by LC-MS/MS and atmospheric pressure chemical ionization

scientific article

Development of a high-throughput method for the determination of itraconazole and its hydroxy metabolite in human plasma, employing automated liquid-liquid extraction based on 96-well format plates and LC/MS/MS.

scientific article

Dried plasma spots as an alternative sample collection technique for the quantitative LC-MS/MS determination of gabapentin.

scientific article published on 9 August 2010

Early screening of FTO and MC4R variants in newborns of Greek origin

scientific article published on 01 May 2015

Effect of the luminol signal enhancer selection on the curve parameters of an immunoassay and the chemiluminescence intensity and kinetics.

scientific article

Effects of derivatization reagents consisting of n-alkyl chloroformate/n-alcohol combinations in LC-ESI-MS/MS analysis of zwitterionic antiepileptic drugs

scientific article published on 07 May 2013

Efficient determination and evaluation of model cyclodextrin complex binding constants by electrospray mass spectrometry

scientific article published in October 2003

Enhanced interpretation of newborn screening results without analyte cutoff values.

scientific article published on 16 February 2012

Expanded newborn screening in Greece: 30 months of experience.

scientific article published on 19 August 2010

Glucose-6-Phosphate Dehydrogenase (G6PD) deficiency in Greek newborns: the Mediterranean C563T mutation screening

scientific article published on 24 January 2014

Hawkinsinuria in two unrelated Greek newborns: identification of a novel variant, biochemical findings and treatment

scientific article published on 01 January 2016

Hematocrit effect on dried blood spots in adults: a computational study and theoretical considerations

scientific article published on 01 June 2019

High incidence of partial biotinidase deficiency cases in newborns of Greek origin ⬇️

scientific article published on April 30, 2013

Identification of five mutations in a patient with galactose metabolic disorders.

scientific article

Improved performance of antigen-HRP conjugate-based immunoassays after the addition of anti-HRP antibody and application of a liposomal chemiluminescence marker

scientific article published on 01 January 2012

Inclusional complex study between 6-p-toluidinylnaphthalene-2-sulfonate and 2-hydroxypropyl-beta-cyclodextrin.

scientific article published in July 2002

Liquid chromatography coupled to quadrupole-time of flight tandem mass spectrometry based quantitative structure-retention relationships of amino acid analogues derivatized via n-propyl chloroformate mediated reaction

scientific article published on 21 May 2015

Mutational analysis for biotinidase deficiency of a Greek patients' cohort ascertained through expanded newborn screening

scientific article published on 20 October 2011

Mutational analysis of GALT gene in Greek patients with galactosaemia: identification of two novel mutations and clinical evaluation.

scientific article published on 23 June 2017

Nutrition and medical support during pregnancy and lactation in women with inborn errors of intermediary metabolism disorders (IEMDs)

scientific article published on 01 January 2020

Partial biotinidase deficiency: identification of a single novel mutation (p.H314R) in a Greek newborn

scientific article published on 01 March 2016

Quantitation of brinzolamide in dried blood spots by a novel LC-QTOF-MS/MS method

scientific article published on 28 November 2015

Quantitation of pregabalin in dried blood spots and dried plasma spots by validated LC-MS/MS methods

scientific article published on 19 February 2015

Quantitation of the arginine family amino acids in the blood of full-term infants perinatally in relation to their birth weight

scientific article published on 01 August 2019

Quantitative determination of donepezil in human plasma by liquid chromatography/tandem mass spectrometry employing an automated liquid-liquid extraction based on 96-well format plates. Application to a bioequivalence study

scientific article published on 17 November 2006

Rare cases of galactose metabolic disorders: identification of more than two mutations per patient.

scientific article

Safety and pharmacokinetics of oseltamivir for prophylaxis of neonates exposed to influenza H1N1

scientific article published on 01 May 2012

Simultaneous determination of losartan, EXP-3174 and hydrochlorothiazide in plasma via fully automated 96-well-format-based solid-phase extraction and liquid chromatography-negative electrospray tandem mass spectrometry

scientific article published on 21 November 2006

Stepwise optimization approach for improving LC-MS/MS analysis of zwitterionic antiepileptic drugs with implementation of experimental design.

scientific article published in July 2013

Study of the effect of CYP2C19 polymorphisms on omeprazole pharmacokinetics by utilizing validated LC-MS/MS and Real Time-PCR methods

scientific article published on 27 June 2016

The novel GABA adamantane derivative (AdGABA): design, synthesis, and activity relationship with gabapentin.

scientific article

The significant role of amino acids during pregnancy: nutritional support

scientific article published on 30 July 2018

The significant role of carnitine and fatty acids during pregnancy, lactation and perinatal period. Nutritional support in specific groups of pregnant women

scientific article published on 01 November 2019

Turbulent flow and ternary column-switching on-line clean-up system for high-throughput quantification of risperidone and its main metabolite in plasma by LC-MS/MS: application to a bioequivalence study

scientific article

Validation of a fully automated high throughput liquid chromatographic/tandem mass spectrometric method for roxithromycin quantification in human plasma. Application to a bioequivalence study

scientific article

Validation of a novel LC-MS/MS method for the quantitation of colistin A and B in human plasma

scientific article published on 02 December 2010

Vigabatrin in dried plasma spots: validation of a novel LC-MS/MS method and application to clinical practice

scientific article published on 27 May 2014

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