List of works - David Simmons

A positive feedback loop involving Gcm1 and Fzd5 directs chorionic branching morphogenesis in the placenta

scientific article

Alcohol exposure impairs trophoblast survival and alters subtype-specific gene expression in vitro

scientific article published on 25 August 2016

Anatomy of the Mouse Placenta Throughout Gestation

Anterograde neuronal circuit tracing using a genetically modified herpes simplex virus expressing EGFP.

scientific article

Branching morphogenesis during development of placental villi

scientific article published on September 2006

C5a receptor signaling prevents folate deficiency-induced neural tube defects in mice

scientific article published on 18 February 2013

Cell-cell adhesion defects in Mrj mutant trophoblast cells are associated with failure to pattern the chorion during early placental development

scientific journal article

Cell-extrinsic requirement for sulfate in regulating hippocampal neurogenesis

scientific article published on 13 July 2020

Chorioallantoic morphogenesis and formation of the placental villous tree.

scientific article

Complement C5aR1 Signaling Promotes Polarization and Proliferation of Embryonic Neural Progenitor Cells through PKCζ.

scientific article published on 28 April 2017

Crim1 has an essential role in glycogen trophoblast cell and sinusoidal-trophoblast giant cell development in the placenta.

scientific article published on 5 January 2012

Deletion of the Syncytin A receptor Ly6e impairs syncytiotrophoblast fusion and placental morphogenesis causing embryonic lethality in mice.

scientific article

Determinants of trophoblast lineage and cell subtype specification in the mouse placenta

scientific article

Distinct brainstem and forebrain circuits receiving tracheal sensory neuron inputs revealed using a novel conditional anterograde transsynaptic viral tracing system.

scientific article published on May 2015

Diverse subtypes and developmental origins of trophoblast giant cells in the mouse placenta

scientific article published on 10 January 2007

Early patterning of the chorion leads to the trilaminar trophoblast cell structure in the placental labyrinth

scientific article

Epithelial magnesium transport by TRPM6 is essential for prenatal development and adult survival

scientific article (publication date: 19 December 2016)

Evidence for multiple sensory circuits in the brain arising from the respiratory system: an anterograde viral tract tracing study in rodents

scientific article

Expression of Cystatin C in the rat endometrium during the peri-implantation period

scientific journal article

Expression of aldehyde dehydrogenase family 1, member A3 in glycogen trophoblast cells of the murine placenta

scientific article published on 13 December 2014

Expression, regulation and putative nutrient-sensing function of taste GPCRs in the heart

scientific article

Fetal loss and hyposulfataemia in pregnant NaS1 transporter null mice

scientific article published on 8 March 2011

Genes, development and evolution of the placenta.

scientific article

Genetic ablation of placental sinusoidal trophoblast giant cells causes fetal growth restriction and embryonic lethality

scientific article published on 30 May 2015

Genome-wide transcriptomic analysis of the forebrain of postnatal Slc13a4<sup>+/-</sup> mice

publication published on 13 July 2021

Human placental sulfate transporter mRNA profiling from term pregnancies identifies abundant SLC13A4 in syncytiotrophoblasts and SLC26A2 in cytotrophoblasts

scientific article published in April 2013

Loss of Rearranged L-Myc Fusion (RLF) results in defects in heart development in the mouse.

scientific article published on 5 December 2016

Ly6e expression is restricted to syncytiotrophoblast cells of the mouse placenta.

scientific article published on 2 July 2013

Maternal corticosterone exposure in the mouse has sex-specific effects on placental growth and mRNA expression.

scientific article published on 23 August 2012

Molecular analysis of sequence and splice variants of the human SLC13A4 sulfate transporter

scientific article

Molecular analysis of the human SLC13A4 sulfate transporter gene promoter.

scientific article published on 26 February 2013

PLET1 (C11orf34), a highly expressed and processed novel gene in pig and mouse placenta, is transcribed but poorly spliced in human

scientific article published on July 2004

Periconceptional alcohol exposure causes female-specific perturbations to trophoblast differentiation and placental formation in the rat

scientific article published on 10 June 2019

Perinatal exposure to high dietary advanced glycation end products in transgenic NOD8.3 mice leads to pancreatic beta cell dysfunction.

scientific article published on 20 November 2017

Placental and fetal cysteine dioxygenase gene expression in mouse gestation.

scientific article

Placental vasculogenesis is regulated by keratin-mediated hyperoxia in murine decidual tissues

scientific article

Placental, renal, and ileal sulfate transporter gene expression in mouse gestation

scientific article published on 23 August 2012

Postimplantation Development of the Chorioallantoic Placenta

article

Postnatal N-acetylcysteine administration rescues impaired social behaviors and neurogenesis in Slc13a4 haploinsufficient mice.

scientific article published on 5 April 2019

Rat endometrial Vdup1 expression: changes related to sensitization for the decidual cell reaction and hormonal control

scientific journal article

Regulation of trophoblast invasion - a workshop report

scientific article published on 20 February 2008

Review: Alterations in placental glycogen deposition in complicated pregnancies: Current preclinical and clinical evidence

scientific article published on 11 January 2017

Review: Nutrient sulfate supply from mother to fetus: Placental adaptive responses during human and animal gestation.

scientific article published on 4 January 2017

Review: Sexual dimorphism in the formation, function and adaptation of the placenta

scientific article published on 8 December 2016

Secondary Placental Defects in Cxadr Mutant Mice

scientific article published on 29 May 2019

Sex differences in rat placental development: from pre-implantation to late gestation

scientific article

Sex specific changes in placental growth and MAPK following short term maternal dexamethasone exposure in the mouse.

scientific article published on 5 October 2011

Sp1/Sp3 compound heterozygous mice are not viable: impaired erythropoiesis and severe placental defects

scientific journal article

Spatial and temporal expression of the 23 murine Prolactin/Placental Lactogen-related genes is not associated with their position in the locus

scientific article

TRPM7 is the central gatekeeper of intestinal mineral absorption essential for postnatal survival

article published in the Proceedings of the National Academy of Sciences of the United States of America

The basic helix-loop-helix transcription factor Hand1 regulates mouse development as a homodimer

scientific journal article

The effect of hyperpolarization-activated cyclic nucleotide-gated ion channel inhibitors on the vagal control of guinea pig airway smooth muscle tone

scientific article

The effects of gestational age and maternal hypoxia on the placental renin angiotensin system in the mouse.

scientific article published on 16 September 2014

Triheptanoin protects against status epilepticus-induced hippocampal mitochondrial dysfunctions, oxidative stress and neuronal degeneration

scientific article

List of works by David Simmons

A positive feedback loop involving Gcm1 and Fzd5 directs chorionic branching morphogenesis in the placenta

Alcohol exposure impairs trophoblast survival and alters subtype-specific gene expression in vitro

Anatomy of the Mouse Placenta Throughout Gestation

Anterograde neuronal circuit tracing using a genetically modified herpes simplex virus expressing EGFP.

Branching morphogenesis during development of placental villi

C5a receptor signaling prevents folate deficiency-induced neural tube defects in mice

Cell-cell adhesion defects in Mrj mutant trophoblast cells are associated with failure to pattern the chorion during early placental development

Cell-extrinsic requirement for sulfate in regulating hippocampal neurogenesis

Chorioallantoic morphogenesis and formation of the placental villous tree.

Complement C5aR1 Signaling Promotes Polarization and Proliferation of Embryonic Neural Progenitor Cells through PKCζ.

Crim1 has an essential role in glycogen trophoblast cell and sinusoidal-trophoblast giant cell development in the placenta.

Deletion of the Syncytin A receptor Ly6e impairs syncytiotrophoblast fusion and placental morphogenesis causing embryonic lethality in mice.

Determinants of trophoblast lineage and cell subtype specification in the mouse placenta

Distinct brainstem and forebrain circuits receiving tracheal sensory neuron inputs revealed using a novel conditional anterograde transsynaptic viral tracing system.

Diverse subtypes and developmental origins of trophoblast giant cells in the mouse placenta

Early patterning of the chorion leads to the trilaminar trophoblast cell structure in the placental labyrinth

Epithelial magnesium transport by TRPM6 is essential for prenatal development and adult survival

Evidence for multiple sensory circuits in the brain arising from the respiratory system: an anterograde viral tract tracing study in rodents

Expression of Cystatin C in the rat endometrium during the peri-implantation period

Expression of aldehyde dehydrogenase family 1, member A3 in glycogen trophoblast cells of the murine placenta

Expression, regulation and putative nutrient-sensing function of taste GPCRs in the heart

Fetal loss and hyposulfataemia in pregnant NaS1 transporter null mice

Genes, development and evolution of the placenta.

Genetic ablation of placental sinusoidal trophoblast giant cells causes fetal growth restriction and embryonic lethality

Genome-wide transcriptomic analysis of the forebrain of postnatal Slc13a4<sup>+/-</sup> mice

Human placental sulfate transporter mRNA profiling from term pregnancies identifies abundant SLC13A4 in syncytiotrophoblasts and SLC26A2 in cytotrophoblasts

Loss of Rearranged L-Myc Fusion (RLF) results in defects in heart development in the mouse.

Ly6e expression is restricted to syncytiotrophoblast cells of the mouse placenta.

Maternal corticosterone exposure in the mouse has sex-specific effects on placental growth and mRNA expression.

Molecular analysis of sequence and splice variants of the human SLC13A4 sulfate transporter

Molecular analysis of the human SLC13A4 sulfate transporter gene promoter.

PLET1 (C11orf34), a highly expressed and processed novel gene in pig and mouse placenta, is transcribed but poorly spliced in human

Periconceptional alcohol exposure causes female-specific perturbations to trophoblast differentiation and placental formation in the rat

Perinatal exposure to high dietary advanced glycation end products in transgenic NOD8.3 mice leads to pancreatic beta cell dysfunction.

Placental and fetal cysteine dioxygenase gene expression in mouse gestation.

Placental vasculogenesis is regulated by keratin-mediated hyperoxia in murine decidual tissues

Placental, renal, and ileal sulfate transporter gene expression in mouse gestation

Postimplantation Development of the Chorioallantoic Placenta

Postnatal N-acetylcysteine administration rescues impaired social behaviors and neurogenesis in Slc13a4 haploinsufficient mice.

Rat endometrial Vdup1 expression: changes related to sensitization for the decidual cell reaction and hormonal control

Regulation of trophoblast invasion - a workshop report

Review: Alterations in placental glycogen deposition in complicated pregnancies: Current preclinical and clinical evidence

Review: Nutrient sulfate supply from mother to fetus: Placental adaptive responses during human and animal gestation.

Review: Sexual dimorphism in the formation, function and adaptation of the placenta

Secondary Placental Defects in Cxadr Mutant Mice

Sex differences in rat placental development: from pre-implantation to late gestation

Sex specific changes in placental growth and MAPK following short term maternal dexamethasone exposure in the mouse.

Sp1/Sp3 compound heterozygous mice are not viable: impaired erythropoiesis and severe placental defects

Spatial and temporal expression of the 23 murine Prolactin/Placental Lactogen-related genes is not associated with their position in the locus

TRPM7 is the central gatekeeper of intestinal mineral absorption essential for postnatal survival

The basic helix-loop-helix transcription factor Hand1 regulates mouse development as a homodimer

The effect of hyperpolarization-activated cyclic nucleotide-gated ion channel inhibitors on the vagal control of guinea pig airway smooth muscle tone

The effects of gestational age and maternal hypoxia on the placental renin angiotensin system in the mouse.

Triheptanoin protects against status epilepticus-induced hippocampal mitochondrial dysfunctions, oxidative stress and neuronal degeneration