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List of works by Lars Kaderali

A fractional programming approach to efficient DNA melting temperature calculation.

scientific article published on 15 March 2005

A new stochastic model for subgenomic hepatitis C virus replication considers drug resistant mutants

scientific article (publication date: 2014)

A novel, diffusely infiltrative xenograft model of human anaplastic oligodendroglioma with mutations in FUBP1, CIC, and IDH1.

scientific article

AAV8-mediated in vivo overexpression of miR-155 enhances the protective capacity of genetically attenuated malarial parasites

scientific article published on 5 September 2014

ABHD5/CGI-58, the Chanarin-Dorfman Syndrome Protein, Mobilises Lipid Stores for Hepatitis C Virus Production

scientific article (publication date: April 2016)

Accurate prediction of neuroblastoma outcome based on miRNA expression profiles

scientific article

Aging is associated with highly defined epigenetic changes in the human epidermis.

scientific article published on 31 October 2013

An RNAi screen identifies KIF15 as a novel regulator of the endocytic trafficking of integrin

scientific article published on 21 March 2014

An integrative approach for a network based meta-analysis of viral RNAi screens

scientific article published on 13 February 2015

Apolipoprotein E codetermines tissue tropism of hepatitis C virus and is crucial for viral cell-to-cell transmission by contributing to a postenvelopment step of assembly

scientific article published on 30 October 2013

Autoantibodies against the exocrine pancreas in autoimmune pancreatitis: gene and protein expression profiling and immunoassays identify pancreatic enzymes as a major target of the inflammatory process.

scientific article

Biological signature characteristics of primary isolates from human immunodeficiency virus type 1 group O in ex vivo human tonsil histocultures.

scientific article

CASPAR: a hierarchical bayesian approach to predict survival times in cancer from gene expression data

scientific article

Cell entry, efficient RNA replication, and production of infectious hepatitis C virus progeny in mouse liver-derived cells.

scientific article published on 18 November 2013

Clearance of persistent hepatitis C virus infection in humanized mice using a claudin-1-targeting monoclonal antibody

scientific article published on 23 March 2015

Comparison of microbiomes from different niches of upper and lower airways in children and adolescents with cystic fibrosis

scientific article

Computational strategies to combat COVID-19: useful tools to accelerate SARS-CoV-2 and coronavirus research

scientific article published on 04 November 2020

Concomitant DNA methylation and transcriptome signatures define epidermal responses to acute solar UV radiation

scientific article published on 31 July 2020

Constitutional de novo and postzygotic mutations in isolated cases of cerebral cavernous malformations

scientific article published on 20 December 2016

Correction: A Novel, Diffusely Infiltrative Xenograft Model of Human Anaplastic Oligodendroglioma with Mutations in FUBP1, CIC, and IDH1.

scientific article published on 6 August 2013

Corrigendum: SAMHD1 is a biomarker for cytarabine response and a therapeutic target in acute myeloid leukemia

article

Deciphering the Origin and Evolution of Hepatitis B Viruses by Means of a Family of Non-enveloped Fish Viruses

scientific article published on 24 August 2017

Detecting host factors involved in virus infection by observing the clustering of infected cells in siRNA screening images

scientific article published on September 2010

Detecting non-uniform clusters in large-scale interaction graphs.

scientific article published on 19 September 2013

Dynamic oscillation of translation and stress granule formation mark the cellular response to virus infection

scientific article published on July 2012

Dynamic probabilistic threshold networks to infer signaling pathways from time-course perturbation data

scientific article

Flunarizine prevents hepatitis C virus membrane fusion in a genotype-dependent manner by targeting the potential fusion peptide within E1.

scientific article published on 6 August 2015

From experimental setup to bioinformatics: an RNAi screening platform to identify host factors involved in HIV-1 replication

scientific article

Genome-Wide DNA Alterations in X-Irradiated Human Gingiva Fibroblasts

scientific article published on 12 August 2020

Hepatitis C virus complete life cycle screen for identification of small molecules with pro- or antiviral activity.

scientific article

Hepatitis C virus replication depends on endosomal cholesterol homeostasis

scientific article published on 18 October 2017

High-throughput RNA interference screens integrative analysis: Towards a comprehensive understanding of the virus-host interplay.

scientific article published on May 2013

High-throughput sequencing of the entire genomic regions of CCM1/KRIT1, CCM2 and CCM3/PDCD10 to search for pathogenic deep-intronic splice mutations in cerebral cavernous malformations.

scientific article published on 20 June 2017

Host factor prioritization for pan-viral genetic perturbation screens using random intercept models and network propagation

scientific article published on 10 February 2020

Hub-centered gene network reconstruction using automatic relevance determination

scientific article

Identification of HNRNPK as regulator of hepatitis C virus particle production

scientific article

Identification of type I and type II interferon-induced effectors controlling hepatitis C virus replication.

scientific article published on 14 October 2012

Impact of raltegravir on HIV-1 RNA and DNA forms following initiation of antiretroviral therapy in treatment-naive patients

scientific article published on 23 June 2014

Incorporation of primary patient-derived glycoproteins into authentic infectious hepatitis C virus particles.

scientific article published on 24 June 2014

Inferring causal molecular networks: empirical assessment through a community-based effort

scientific article

Isolate-dependent use of claudins for cell entry by hepatitis C virus

scientific article published on January 2014

MAP-kinase regulated cytosolic phospholipase A2 activity is essential for production of infectious hepatitis C virus particles

scientific article

Mathematical modeling of hepatitis C RNA replication, exosome secretion and virus release

scientific article published on 05 November 2020

Mining quasi-bicliques from HIV-1-human protein interaction network: a multiobjective biclustering approach

scientific article published on March 2013

Modeling transcriptomic age using knowledge-primed artificial neural networks

scientific article published in 2021

Molecular mechanism of signal perception and integration by the innate immune sensor retinoic acid-inducible gene-I (RIG-I).

scientific article

Multi-scale model for hepatitis C viral load kinetics under treatment with direct acting antivirals

scientific article published on 23 September 2015

Normalizing for individual cell population context in the analysis of high-content cellular screens

scientific article

Novel CIC point mutations and an exon-spanning, homozygous deletion identified in oligodendroglial tumors by a comprehensive genomic approach including transcriptome sequencing

scientific article

Oral Health and Quality of Life in Old Age: A Cross-Sectional Pilot Project in Germany and Poland

scientific article

Phosphorylation-Dependent Feedback Inhibition of RIG-I by DAPK1 Identified by Kinome-wide siRNA Screening

scientific article published on 14 January 2017

Postoperative course and prognostic value of circulating angiogenic cytokines after pancreatic cancer resection

scientific article published on 17 August 2017

Primer design for multiplexed genotyping.

scientific article published on January 2007

Prognostic impact of gene expression-based classification for neuroblastoma.

scientific article published on 21 June 2010

Proteome analysis of the HIV-1 Gag interactome

scientific article published on 10 June 2014

Quantitative Proteomics Identifies Serum Response Factor Binding Protein 1 as a Host Factor for Hepatitis C Virus Entry

scientific article published on 23 July 2015

Quantitative interpretation of PF4/heparin‐EIA optical densities in predicting platelet‐activating VITT antibodies

scientific article published in 2022

RNAither, an automated pipeline for the statistical analysis of high-throughput RNAi screens

scientific article

Reanalysis of neuroblastoma expression profiling data using improved methodology and extended follow-up increases validity of outcome prediction

scientific article

Reconstructing nonlinear dynamic models of gene regulation using stochastic sampling

scientific article

Reconstructing signaling pathways from RNAi data using probabilistic Boolean threshold networks

scientific article

Reconstruction of cellular signal transduction networks using perturbation assays and linear programming.

scientific article

Recruitment and activation of a lipid kinase by hepatitis C virus NS5A is essential for integrity of the membranous replication compartment

scientific article

Reduced DNA methylation patterning and transcriptional connectivity define human skin aging.

scientific article published on 23 March 2016

Replication vesicles are load- and choke-points in the hepatitis C virus lifecycle

scientific article

Retrospective survival analysis of 237 consecutive patients with multiple pulmonary metastases from advanced renal cell carcinoma exclusively resected by a 1318-nm laser

scientific article published on 14 May 2015

Rif2 promotes a telomere fold-back structure through Rpd3L recruitment in budding yeast

scientific article

Role of hypervariable region 1 for the interplay of hepatitis C virus with entry factors and lipoproteins

scientific article published on 20 August 2014

SAMHD1 is a biomarker for cytarabine response and a therapeutic target in acute myeloid leukemia.

scientific article

Selecting signature oligonucleotides to identify organisms using DNA arrays

scientific article published in October 2002

Several Human Liver Cell Expressed Apolipoproteins Complement HCV Virus Production with Varying Efficacy Conferring Differential Specific Infectivity to Released Viruses

scientific article published on 30 July 2015

Subclassification and individual survival time prediction from gene expression data of neuroblastoma patients by using CASPAR.

scientific article

Systems biology of viral infection.

scientific article published in June 2016

Tec-kinase-mediated phosphorylation of fibroblast growth factor 2 is essential for unconventional secretion

scientific article published on 10 March 2010

The SUMOylation Pathway Restricts Gene Transduction by Adeno-Associated Viruses

scientific article published in December 2015

The biological age linked to oxidative stress modifies breast cancer aggressiveness.

scientific article published on 14 March 2018

Transcriptome analysis reveals a classical interferon signature induced by IFNλ4 in human primary cells.

scientific article

Translating expression profiling into a clinically feasible test to predict neuroblastoma outcome

scientific article published in March 2007

Whither systems medicine?

scientific article published on 2 March 2018

hepatitis c Virus p7 is critical for capsid assembly and envelopment

scientific article

lpNet: a linear programming approach to reconstruct signal transduction networks.

scientific article

miR-17-5p regulates endocytic trafficking through targeting TBC1D2/Armus

scientific article

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