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List of works by Susan O Meakin

A differential role of extracellular signal-regulated kinase in stimulated PC12 pheochromocytoma cell movement

article published in 2001

Acidic substitution of the activation loop tyrosines in TrkA supports nerve growth factor-dependent, but not nerve growth factor-independent, differentiation and cell cycle arrest in the human neuroblastoma cell line, SY5Y.

scientific article published on November 2003

Activity-dependent interaction of the intracellular domain of rat trkA with intermediate filament proteins, the beta-6 proteasomal subunit, Ras-GRF1, and the p162 subunit of eIF3

scientific journal article

Arf6 controls beta-amyloid production by regulating macropinocytosis of the Amyloid Precursor Protein to lysosomes

scientific article

Cyclic phosphatidic acid elicits neurotrophin‐like actions in embryonic hippocampal neurons ⬇️

scientific article published on December 1, 2003

Deletions in the extracellular domain of rat trkA lead to an altered differentiative phenotype in neurotrophin responsive cells

scientific article published on 01 May 1996

Direct binding of the signaling adapter protein Grb2 to the activation loop tyrosines on the nerve growth factor receptor tyrosine kinase, TrkA

scientific article (publication date: 16 June 2000)

Ectopic expression of the TrkA receptor in adult dopaminergic mesencephalic neurons promotes retrograde axonal NGF transport and NGF-dependent neuroprotection.

scientific article published on October 2003

Genomic organization and comparative sequence analysis of the mouse and human FRS2, FRS3 genes

scientific article published on 01 March 2003

Human tumorous imaginal disc 1 (TID1) associates with Trk receptor tyrosine kinases and regulates neurite outgrowth in nnr5-TrkA cells.

scientific article

Imaging chemical exchange saturation transfer (CEST) effects following tumor-selective acidification using lonidamine.

scientific article published on 23 March 2015

In vivo detection of MRI-PARACEST agents in mouse brain tumors at 9.4 T.

scientific article

Nerve growth factor activation of the TrkA receptor induces cell death, by macropinocytosis, in medulloblastoma Daoy cells

scientific article

Nesca, a novel neuronal adapter protein, links the molecular motor kinesin with the pre‐synaptic membrane protein, syntaxin‐1, in hippocampal neurons ⬇️

scientific article published on April 2, 2012

Neurotrophin-dependent tyrosine phosphorylation of Ras guanine-releasing factor 1 and associated neurite outgrowth is dependent on the HIKE domain of TrkA.

scientific article

Overexpression of the signaling adapter FRS2 reconstitutes the cell cycle deficit of a nerve growth factor non-responsive TrkA receptor mutant.

scientific article

PC12nnr5 cells expressing TrkA receptors undergo morphological but not cholinergic phenotypic differentiation in response to nerve growth factor

scientific article published in February 2002

Quantitative tissue pH measurement during cerebral ischemia using amine and amide concentration-independent detection (AACID) with MRI.

scientific article

Ras guanine nucleotide releasing factor 1 (RasGrf1) enhancement of Trk receptor-mediated neurite outgrowth requires activation of both H-Ras and Rac.

scientific article published on 29 June 2012

Role and expression of FRS2 and FRS3 in prostate cancer

scientific article

ShcB and ShcC activation by the Trk family of receptor tyrosine kinases

scientific article (publication date: 19 July 2002)

Subpopulations of rat B2(+) neuroblasts exhibit differential neurotrophin responsiveness during sympathetic development

scientific article published on 01 February 2000

The fibroblast growth factor receptor substrate 3 adapter is a developmentally regulated microtubule-associated protein expressed in migrating and differentiated neurons.

scientific article published on 24 November 2009

The nerve growth factor family of receptors

scientific article published on September 1, 1992

The signaling adapter, FRS2, facilitates neuronal branching in primary cortical neurons via both Grb2- and Shp2-dependent mechanisms

scientific article

The signaling adapters fibroblast growth factor receptor substrate 2 and 3 are activated by the thyroid TRK oncoproteins.

scientific article

Trk receptor binding and neurotrophin/fibroblast growth factor (FGF)-dependent activation of the FGF receptor substrate (FRS)-3

scientific article published on 21 March 2006

TrkB Regulates N-Methyl-D-Aspartate Receptor Signaling by Uncoupling and Recruiting the Brain-Specific Guanine Nucleotide Exchange Factor, RasGrf1

scientific article published on 13 December 2018

Trypanosome trans-sialidase targets TrkA tyrosine kinase receptor and induces receptor internalization and activation.

scientific article published on 7 July 2004

Unravelling the Mechanism of TrkA-Induced Cell Death by Macropinocytosis in Medulloblastoma Daoy Cells

scientific article published on 8 August 2016

p75 Co-receptors regulate ligand-dependent and ligand-independent Trk receptor activation, in part by altering Trk docking subdomains.

scientific article

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