List of works - Helmout Modjtahedi

A comprehensive review of the preclinical efficacy profile of the ErbB family blocker afatinib in cancer

scientific article

Aberrant DNA methylation of PTPRG as one possible mechanism of its under-expression in CML patients in the State of Qatar

scientific article published on 23 July 2020

Acquired resistance of pancreatic cancer cells to treatment with gemcitabine and HER-inhibitors is accompanied by increased sensitivity to STAT3 inhibition.

scientific article published on 5 January 2016

Acquired resistance to anti-EGFR mAb ICR62 in cancer cells is accompanied by an increased EGFR expression, HER-2/HER-3 signalling and sensitivity to pan HER blockers.

scientific article published on 15 September 2015

Amplification and expression of EGFR and ERBB2 in Wilms tumor

scientific article published on 01 October 2009

Analysis of the immunomodulatory properties of two heat-killed mycobacterial preparations in a human whole blood model

scientific article

Anti-tumour activity of afatinib, an irreversible ErbB family blocker, in human pancreatic tumour cells

scientific article published on 4 October 2011

Antitumor activity of combinations of antibodies directed against different epitopes on the extracellular domain of the human EGF receptor

scientific article published on 01 January 1993

Co-expression of HER family members in patients with Dukes' C and D colon cancer and their impacts on patient prognosis and survival

scientific article

Development and application of two novel monoclonal antibodies against overexpressed CD26 and integrin α3 in human pancreatic cancer

scientific article published on 17 January 2020

EGF mediates monocyte chemotaxis and macrophage proliferation and EGF receptor is expressed in atherosclerotic plaques

article

Epidermal growth factor receptor inhibitors in cancer treatment: advances, challenges and opportunities.

scientific article

Epitope mapping of epidermal growth factor receptor (EGFR) monoclonal antibody and induction of growth-inhibitory polyclonal antibodies by vaccination with EGFR mimotope

scientific article

Expression pattern and targeting of HER family members and IGF-IR in pancreatic cancer.

scientific article published on June 2012

GA201: a novel humanized and glycoengineered anti-EGFR antibody--letter.

scientific article published in February 2014

Growth response of human colorectal tumour cell lines to treatment with afatinib (BIBW2992), an irreversible erbB family blocker, and its association with expression of HER family members ⬇️

scientific article published on May 25, 2011

Immunohistochemical discrimination of wild-type EGFR from EGFRvIII in fixed tumour specimens using anti-EGFR mAbs ICR9 and ICR10 ⬇️

scientific article published on February 7, 2012

Immunotherapy of human tumour xenografts overexpressing the EGF receptor with rat antibodies that block growth factor-receptor interaction ⬇️

scientific article published on February 1, 1993

Impact of the putative cancer stem cell markers and growth factor receptor expression on the sensitivity of ovarian cancer cells to treatment with various forms of small molecule tyrosine kinase inhibitors and cytotoxic drugs.

scientific article published on 05 September 2016

Inhibitory Effects of Culinary Herbs and Spices on the Growth of HCA-7 Colorectal Cancer Cells and Their COX-2 Expression.

scientific article

Molecular therapy of head and neck cancer.

scientific article

Periadventitial delivery of anti-EGF receptor antibody inhibits neointimal macrophage accumulation after angioplasty in a hypercholesterolaemic rabbit

scientific article published on 11 December 2009

Production and characterization of a new antibody specific for the mutant EGF receptor, EGFRvIII, in Camelus bactrianus.

scientific article

Production of a novel camel single-domain antibody specific for the type III mutant EGFR.

scientific article

Prognostic significance and targeting of HER family in colorectal cancer ⬇️

scientific article published on January 1, 2013

Responses of human colorectal tumor cells to treatment with the anti-epidermal growth factor receptor monoclonal antibody ICR62 used alone and in combination with the EGFR tyrosine kinase inhibitor gefitinib.

scientific article published on August 2006

Resveratrol 3-O-D-glucuronide and resveratrol 4'-O-D-glucuronide inhibit colon cancer cell growth: evidence for a role of A3 adenosine receptors, cyclin D1 depletion, and G1 cell cycle arrest.

scientific article published on 7 May 2013

Synergistic effects of various Her inhibitors in combination with IGF-1R, C-MET and Src targeting agents in breast cancer cell lines

scientific article

The epidermal growth factor receptors and their family of ligands: their putative role in atherogenesis

scientific article

The expression of p53, c-erbB-1 and c-erbB-2 molecules and their correlation with prognostic markers in patients with head and neck tumors

scientific article published on 01 October 2002

Therapeutic application of monoclonal antibodies in cancer: advances and challenges

scientific article published on 31 October 2012

Treatment with a combination of the ErbB (HER) family blocker afatinib and the IGF-IR inhibitor, NVP-AEW541 induces synergistic growth inhibition of human pancreatic cancer cells.

scientific article

Vascular endothelial growth factor family members are differentially regulated by c-erbB signaling in head and neck squamous carcinoma cells.

scientific article published on January 2000

List of works by Helmout Modjtahedi

A comprehensive review of the preclinical efficacy profile of the ErbB family blocker afatinib in cancer

Aberrant DNA methylation of PTPRG as one possible mechanism of its under-expression in CML patients in the State of Qatar

Acquired resistance of pancreatic cancer cells to treatment with gemcitabine and HER-inhibitors is accompanied by increased sensitivity to STAT3 inhibition.

Acquired resistance to anti-EGFR mAb ICR62 in cancer cells is accompanied by an increased EGFR expression, HER-2/HER-3 signalling and sensitivity to pan HER blockers.

Amplification and expression of EGFR and ERBB2 in Wilms tumor

Analysis of the immunomodulatory properties of two heat-killed mycobacterial preparations in a human whole blood model

Anti-tumour activity of afatinib, an irreversible ErbB family blocker, in human pancreatic tumour cells

Antitumor activity of combinations of antibodies directed against different epitopes on the extracellular domain of the human EGF receptor

Co-expression of HER family members in patients with Dukes' C and D colon cancer and their impacts on patient prognosis and survival

Development and application of two novel monoclonal antibodies against overexpressed CD26 and integrin α3 in human pancreatic cancer

EGF mediates monocyte chemotaxis and macrophage proliferation and EGF receptor is expressed in atherosclerotic plaques

Epidermal growth factor receptor inhibitors in cancer treatment: advances, challenges and opportunities.

Epitope mapping of epidermal growth factor receptor (EGFR) monoclonal antibody and induction of growth-inhibitory polyclonal antibodies by vaccination with EGFR mimotope

Expression pattern and targeting of HER family members and IGF-IR in pancreatic cancer.

GA201: a novel humanized and glycoengineered anti-EGFR antibody--letter.

Growth response of human colorectal tumour cell lines to treatment with afatinib (BIBW2992), an irreversible erbB family blocker, and its association with expression of HER family members ⬇️

Immunohistochemical discrimination of wild-type EGFR from EGFRvIII in fixed tumour specimens using anti-EGFR mAbs ICR9 and ICR10 ⬇️

Immunotherapy of human tumour xenografts overexpressing the EGF receptor with rat antibodies that block growth factor-receptor interaction ⬇️

Impact of the putative cancer stem cell markers and growth factor receptor expression on the sensitivity of ovarian cancer cells to treatment with various forms of small molecule tyrosine kinase inhibitors and cytotoxic drugs.

Inhibitory Effects of Culinary Herbs and Spices on the Growth of HCA-7 Colorectal Cancer Cells and Their COX-2 Expression.

Molecular therapy of head and neck cancer.

Periadventitial delivery of anti-EGF receptor antibody inhibits neointimal macrophage accumulation after angioplasty in a hypercholesterolaemic rabbit

Production and characterization of a new antibody specific for the mutant EGF receptor, EGFRvIII, in Camelus bactrianus.

Production of a novel camel single-domain antibody specific for the type III mutant EGFR.

Prognostic significance and targeting of HER family in colorectal cancer ⬇️

Responses of human colorectal tumor cells to treatment with the anti-epidermal growth factor receptor monoclonal antibody ICR62 used alone and in combination with the EGFR tyrosine kinase inhibitor gefitinib.

Resveratrol 3-O-D-glucuronide and resveratrol 4'-O-D-glucuronide inhibit colon cancer cell growth: evidence for a role of A3 adenosine receptors, cyclin D1 depletion, and G1 cell cycle arrest.

Synergistic effects of various Her inhibitors in combination with IGF-1R, C-MET and Src targeting agents in breast cancer cell lines

The epidermal growth factor receptors and their family of ligands: their putative role in atherogenesis

The expression of p53, c-erbB-1 and c-erbB-2 molecules and their correlation with prognostic markers in patients with head and neck tumors

Therapeutic application of monoclonal antibodies in cancer: advances and challenges

Treatment with a combination of the ErbB (HER) family blocker afatinib and the IGF-IR inhibitor, NVP-AEW541 induces synergistic growth inhibition of human pancreatic cancer cells.

Vascular endothelial growth factor family members are differentially regulated by c-erbB signaling in head and neck squamous carcinoma cells.