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List of works by Aaron G Smith

A growth hormone receptor SNP promotes lung cancer by impairment of SOCS2-mediated degradation

scientific article

A polymorphism in IRF4 affects human pigmentation through a tyrosinase-dependent MITF/TFAP2A pathway

scientific article

Assessing the influence of soil freeze–thaw cycles on catchment water storage–flux–age interactions using a tracer-aided ecohydrological model

BRN2, a POUerful driver of melanoma phenotype switching and metastasis

scientific article published on 05 June 2018

Catchment Functioning Under Prolonged Drought Stress: Tracer‐Aided Ecohydrological Modeling in an Intensively Managed Agricultural Catchment

scientific article

Chromosomal structure of the human TYRP1 and TYRP2 loci and comparison of the tyrosinase-related protein gene family

scientific article

Co-expression of SOX9 and SOX10 during melanocytic differentiation in vitro.

scientific article

Domains of Brn-2 that mediate homodimerization and interaction with general and melanocytic transcription factors

scientific article

Expansion of the lateral ventricles and ependymal deficits underlie the hydrocephalus evident in mice lacking the transcription factor NFIX.

scientific article published on 7 May 2015

Genetic variation in IRF4 expression modulates growth characteristics, tyrosinase expression and interferon-gamma response in melanocytic cells.

scientific article

Halofenate is a selective peroxisome proliferator-activated receptor gamma modulator with antidiabetic activity.

scientific article published on September 2006

MC1R and NR4A receptors in cellular stress and DNA repair: implications for UVR protection

scientific article published on July 2014

Melanocortin-1 receptor signaling markedly induces the expression of the NR4A nuclear receptor subgroup in melanocytic cells

scientific article

Modelling ecohydrological feedbacks in forest and grassland plots under a prolonged drought anomaly in Central Europe 2018–2020

NFIA controls telencephalic progenitor cell differentiation through repression of the Notch effector Hes1.

scientific article published on July 2010

NFIB Mediates BRN2 Driven Melanoma Cell Migration and Invasion Through Regulation of EZH2 and MITF.

scientific article

NFIB-mediated repression of the epigenetic factor Ezh2 regulates cortical development

scientific article published on February 2014

NFIX Regulates Proliferation and Migration Within the Murine SVZ Neurogenic Niche

scientific article

NFIX regulates neural progenitor cell differentiation during hippocampal morphogenesis

scientific article published on 04 October 2012

NR4A2 Promotes DNA Double-strand Break Repair Upon Exposure to UVR.

scientific article published on 12 June 2017

Non-DNA binding, dominant-negative, human PPARgamma mutations cause lipodystrophic insulin resistance

scientific article published on October 2006

Nuclear factor one transcription factors as epigenetic regulators in cancer.

scientific article published on 11 January 2017

Nuclear receptor function in skin health and disease: therapeutic opportunities in the orphan and adopted receptor classes.

scientific article published on 20 August 2016

Orphan nuclear receptors: therapeutic opportunities in skeletal muscle.

scientific article published on August 2006

PPARgamma agonists attenuate proliferation and modulate Wnt/beta-catenin signalling in melanoma cells.

scientific article published on 6 September 2008

PRMT2 and RORγ expression are associated with breast cancer survival outcomes

scientific article

Quantifying the effects of land use and model scale on water partitioning and water ages using tracer-aided ecohydrological models

Quantifying the effects of urban green space on water partitioning and ages using an isotope-based ecohydrological model

Reciprocal Regulation of BRN2 and NOTCH1/2 Signaling Synergistically Drives Melanoma Cell Migration and Invasion

scientific article published in 2022

Redox regulation of Brn-2/N-Oct-3 POU domain DNA binding activity and proteolytic formation of N-Oct-5 during melanoma cell nuclear extraction.

scientific article

Regulation of NR4A nuclear receptor expression by oncogenic BRAF in melanoma cells.

scientific article published on 31 March 2011

Riparian wetland rehabilitation and beaver re-colonization impacts on hydrological processes and water quality in a lowland agricultural catchment

scientific article published on 07 September 2019

Skeletal muscle and nuclear hormone receptors: implications for cardiovascular and metabolic disease

scientific article

Spatially distributed tracer-aided runoff modelling and dynamics of storage and water ages in a permafrost-influenced catchment

scientific article

Stable isotopes of water reveal differences in plant – soil water relationships across northern environments

The NR4A2 nuclear receptor is recruited to novel nuclear foci in response to UV irradiation and participates in nucleotide excision repair

scientific article

The recycling endosome protein Rab17 regulates melanocytic filopodia formation and melanosome trafficking

scientific journal article

Tyrosine agonists reverse the molecular defects associated with dominant-negative mutations in human peroxisome proliferator-activated receptor gamma.

scientific article published on 4 December 2003

Using isotopes to incorporate tree water storage and mixing dynamics into a distributed ecohydrologic modelling framework

Using soil water isotopes to infer the influence of contrasting urban green space on ecohydrological partitioning

scientific article

Using stable isotopes to estimate travel times in a data-sparse Arctic catchment: Challenges and possible solutions

article