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List of works by Daniel J Gough

A STAT3-mediated metabolic switch is involved in tumour transformation and STAT3 addiction.

scientific article

A Synthetic Lethal Interaction between Glutathione Synthesis and Mitochondrial Reactive Oxygen Species Provides a Tumor-Specific Vulnerability Dependent on STAT3.

scientific article published on 17 August 2015

A novel c-Jun-dependent signal transduction pathway necessary for the transcriptional activation of interferon gamma response genes

scientific article published on 14 November 2006

A phase IIa study of HA-irinotecan, formulation of hyaluronic acid and irinotecan targeting CD44 in extensive-stage small cell lung cancer.

scientific article

Constitutive type I interferon modulates homeostatic balance through tonic signaling

scientific article

Cre-dependent DNA recombination activates a STING-dependent innate immune response

scientific article published on 10 May 2016

Cyclin-dependent kinase 7 is a therapeutic target in high-grade glioma.

scientific article published on 15 May 2017

Deep multi-region whole-genome sequencing reveals heterogeneity and gene-by-environment interactions in treatment-naive, metastatic lung cancer

article

Discovery and Validation of Novel Protein Biomarkers in Ovarian Cancer Patient Urine

scientific article published on 9 February 2018

Endometrial Mesenchymal Stem/Stromal Cells Modulate the Macrophage Response to Implanted Polyamide/Gelatin Composite Mesh in Immunocompromised and Immunocompetent Mice.

scientific article

Functional crosstalk between type I and II interferon through the regulated expression of STAT1.

scientific article

IFNgamma signaling-does it mean JAK-STAT?

scientific article published on 16 October 2008

JNK Activation of BIM Promotes Hepatic Oxidative Stress, Steatosis, and Insulin Resistance in Obesity.

scientific article

Mitochondrial DNA copy number is regulated by DNA methylation and demethylation of POLGA in stem and cancer cells and their differentiated progeny

scientific article

Mitochondrial DNA haplotypes induce differential patterns of DNA methylation that result in differential chromosomal gene expression patterns.

scientific article published on 11 September 2017

Mitochondrial STAT3 supports Ras-dependent oncogenic transformation.

scientific article published on June 2009

Mitochondrial STAT3: Powering up a potent factor

scientific article

Mitochondrial arginase-2 is essential for IL-10 metabolic reprogramming of inflammatory macrophages

scientific article published on 05 March 2021

Nongenomic STAT5-dependent effects on Golgi apparatus and endoplasmic reticulum structure and function

scientific article published on 7 December 2011

STAT3 serine phosphorylation is required for TLR4 metabolic reprogramming and IL-1β expression

scientific article published on 30 July 2020

STAT3 supports experimental K-RasG12D-induced murine myeloproliferative neoplasms dependent on serine phosphorylation.

scientific article

STAT3: a multifaceted oncoprotein

scientific article published on 01 April 2018

The JAK/STAT pathway in obesity and diabetes

scientific article published on 12 March 2016

The MEK-ERK pathway is necessary for serine phosphorylation of mitochondrial STAT3 and Ras-mediated transformation

scientific article

The Role of p202 in Regulating Hematopoietic Cell Proliferation and Differentiation

scientific article published on 01 January 2008

The tumor suppressor Hic1 maintains chromosomal stability independent of Tp53.

scientific article

Therapeutically exploiting STAT3 activity in cancer - using tissue repair as a road map

scientific article published on 01 February 2019

Toll-like receptor 2 regulates metabolic reprogramming in gastric cancer via superoxide dismutase 2

scientific article published on 07 January 2019

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