List of works by Peter Ghazal

A DNA nanoswitch incorporating the fluorescent base analogue 2-aminopurine detects single nucleotide mismatches in unlabelled targets

scientific article published on 13 July 2009

A comprehensive machine-readable view of the mammalian cholesterol biosynthesis pathway

scientific article published on 10 April 2013

A logic-based diagram of signalling pathways central to macrophage activation

scientific article

A loss of function analysis of host factors influencing Vaccinia virus replication by RNA interference

scientific article published on 5 June 2014

A model of flux regulation in the cholesterol biosynthesis pathway: Immune mediated graduated flux reduction versus statin-like led stepped flux reduction

scientific article published on June 2012

A multiplexed protein microarray for the simultaneous serodiagnosis of human immunodeficiency virus/hepatitis C virus infection and typing of whole blood.

scientific article published on 26 July 2008

A systematic analysis of host factors reveals a Med23-interferon-λ regulatory axis against herpes simplex virus type 1 replication

scientific article

A temporal gate for viral enhancers to co-opt Toll-like-receptor transcriptional activation pathways upon acute infection

scientific article

Ablation of the regulatory IE1 protein of murine cytomegalovirus alters in vivo pro-inflammatory TNF-alpha production during acute infection

scientific article

An Interferon Regulated MicroRNA Provides Broad Cell-Intrinsic Antiviral Immunity through Multihit Host-Directed Targeting of the Sterol Pathway

scientific article

An essential role of the enhancer for murine cytomegalovirus in vivo growth and pathogenesis

scientific article

Assessment of transcriptomal analysis of Varicella-Zoster-virus gene expression in patients with and without post-herpetic neuralgia

scientific article published on 23 July 2010

Bait-and-Switch Molecular Recognition in Nucleic Acid Sensors: Time-Resolved Fluorescence, Single Nucleotide Polymorphism Detection

article published in 2009

CD200 receptor restriction of myeloid cell responses antagonizes antiviral immunity and facilitates cytomegalovirus persistence within mucosal tissue

scientific article published on 5 February 2015

Cell interaction microarray for blood phenotyping

scientific article published on March 2006

Characterization of the sequences of the human cytomegalovirus enhancer that mediate differential regulation by natural and synthetic retinoids

scientific article published on 01 July 1996

Combined agonist-antagonist genome-wide functional screening identifies broadly active antiviral microRNAs

scientific article

Combined genome-wide expression profiling and targeted RNA interference in primary mouse macrophages reveals perturbation of transcriptional networks associated with interferon signalling

scientific article

Complete genome sequence and lytic phase transcription profile of a Coccolithovirus

scientific article

Construction of a large scale integrated map of macrophage pathogen recognition and effector systems

scientific article

Cytomegalovirus-Specific IL-10-Producing CD4+ T Cells Are Governed by Type-I IFN-Induced IL-27 and Promote Virus Persistence

scientific article

DNA Nanoswitch as a Biosensor

scientific article published on 18 May 2007

Deciphering the modulation of gene expression by type I and II interferons combining 4sU-tagging, translational arrest and in silico promoter analysis.

scientific article published on 05 July 2013

Defective interleukin (IL)-18-mediated natural killer and T helper cell type 1 responses in IL-1 receptor-associated kinase (IRAK)-deficient mice

scientific article

Detection of single nucleotide polymorphisms using a DNA Holliday junction nanoswitch—a high-throughput fluorescence lifetime assay

article published in 2010

Development of immunosensors for direct detection of three wound infection biomarkers at point of care using electrochemical impedance spectroscopy

article

Development of non-agglutination microarray blood grouping

article

Dielectrophoretic manipulation of ribosomal RNA.

scientific article

Digital clocks: simple Boolean models can quantitatively describe circadian systems

scientific article published on 12 April 2012

Discrete clusters of virus-encoded micrornas are associated with complementary strands of the genome and the 7.2-kilobase stable intron in murine cytomegalovirus

scientific article (publication date: December 2007)

Dominance of virus over host factors in cross-species activation of human cytomegalovirus early gene expression

scientific article

Draft Genome Sequence of a Pantoea sp. Isolated from a Preterm Neonatal Blood Sepsis Patient

scientific article published on 11 September 2014

Draft Genome Sequence of a Serratia marcescens Strain Isolated from a Preterm Neonatal Blood Sepsis Patient at the Royal Infirmary, Edinburgh, Scotland, United Kingdom.

scientific article published on 11 September 2014

Draft Genome Sequence of a Staphylococcus aureus Isolate Taken from the Blood of a Preterm Neonatal Blood Sepsis Patient

scientific article published on 11 September 2014

Draft Genome Sequence of a Staphylococcus warneri Strain Isolated from a Preterm Neonate Blood Sepsis Patient at the Royal Infirmary, Edinburgh, Scotland

scientific article published on 4 September 2014

Draft Genome Sequence of a Streptococcus agalactiae Strain Isolated from a Preterm Neonate Blood Sepsis Patient at the Royal Infirmary, Edinburgh, Scotland

scientific article published on 4 September 2014

Draft Genome Sequence of an Enterococcus faecalis Strain Isolated from a Neonatal Blood Sepsis Patient

scientific article published on 11 September 2014

Draft Genome Sequences of Six Different Staphylococcus epidermidis Clones, Isolated Individually from Preterm Neonates Presenting with Sepsis at Edinburgh's Royal Infirmary

scientific article published on 14 May 2015

Electrochemical control of a DNA Holliday Junction nanoswitch by Mg2+ ions.

scientific article published on 4 May 2008

Electrodeposition of platinum metal on TiN thin films

Elimination of ie1 significantly attenuates murine cytomegalovirus virulence but does not alter replicative capacity in cell culture

scientific article

Endometrial cysteine-rich secretory protein 3 is inhibited by human chorionic gonadotrophin, and is increased in the decidua of tubal ectopic pregnancy

scientific article published on 12 March 2009

Endometrial inhibin/activin beta-B subunit expression is related to decidualization and is reduced in tubal ectopic pregnancy.

scientific article

Enhancerless cytomegalovirus is capable of establishing a low-level maintenance infection in severely immunodeficient host tissues but fails in exponential growth.

scientific article

Estimation of expression levels in spotted microarrays with saturated pixels

scientific article

Evaluation of a Protein Microarray Method for Immuno‐Typing Erythrocytes in Whole Blood

scientific article published on 01 January 2008

Evaluation of perturbed iron-homeostasis in a prospective cohort of patients with COVID-19

scientific article published on 21 June 2022

Evolutionary Origin of the Interferon-Immune Metabolic Axis: The Sterol-Vitamin D Link

scientific article published on 9 February 2017

Exploiting parallel R in the cloud with SPRINT

scientific article published on 7 December 2012

Extending Signaling Pathways with Protein–Interaction Networks. Application to Apoptosis

scientific article published on 02 March 2012

Fast DNA and protein microarray tests for the diagnosis of hepatitis C virus infection on a single platform

scientific article published in September 2011

Fluorescence Lifetime Imaging of Quantum Dot Labeled DNA Microarrays

scientific article

Forskolin inducibility and tissue-specific expression of the fibronectin promoter

scientific article published on April 1989

GPX-Macrophage Expression Atlas: a database for expression profiles of macrophages challenged with a variety of pro-inflammatory, anti-inflammatory, benign and pathogen insults

scientific article

Gene expression profiling of mid to late secretory phase endometrial biopsies from women with menstrual complaint

scientific article published on August 2006

General and specific alterations in programming of global viral gene expression during infection by VP16 activation-deficient mutants of herpes simplex virus type 1.

scientific article published on December 2002

Genome-wide expression profiling of in vivo-derived bloodstream parasite stages and dynamic analysis of mRNA alterations during synchronous differentiation in Trypanosoma brucei

scientific article

Genome-wide reduction in transcriptomal profiles of varicella-zoster virus vaccine strains compared with parental Oka strain using long oligonucleotide microarrays

scientific article

Genomic Programming of Human Neonatal Dendritic Cells in Congenital Systemic and In Vitro Cytomegalovirus Infection Reveal Plastic and Robust Immune Pathway Biology Responses

scientific article published on 25 September 2017

HBLAST: Parallelised sequence similarity--A Hadoop MapReducable basic local alignment search tool

scientific article published on 24 January 2015

High-resolution gene expression profiling for simultaneous kinetic parameter analysis of RNA synthesis and decay

scientific article published on 24 July 2008

High-throughput sequence analysis of variants of human cytomegalovirus strains Towne and AD169.

scientific article

Host defense against viral infection involves interferon mediated down-regulation of sterol biosynthesis

scientific article

Human cytomegalovirus UL7, a homologue of the SLAM-family receptor CD229, impairs cytokine production

scientific article published on 14 June 2011

Identification of a boundary domain adjacent to the potent human cytomegalovirus enhancer that represses transcription of the divergent UL127 promoter

scientific article

Identification of a human neonatal immune-metabolic network associated with bacterial infection

scientific article

Immediate-early expression of the herpes simplex virus type 1 ICP27 transcript is not critical for efficient replication in vitro or in vivo

scientific article

Immune oxysterols: Role in mycobacterial infection and inflammation

scientific article

Impedimetric detection of single-stranded PCR products derived from methicillin resistant Staphylococcus aureus (MRSA) isolates.

scientific article published on 9 February 2012

Improved silicon nitride surfaces for next-generation microarrays

scientific article published on December 2006

In vivo competence of murine cytomegalovirus under the control of the human cytomegalovirus major immediate-early enhancer in the establishment of latency and reactivation

scientific article published on 06 August 2008

In vivo transduction of photoreceptors or ciliary body by intravitreal injection of pseudotyped adenoviral vectors

scientific article

Inference of transition probabilities between the attractors in Boolean networks with perturbation

Inferring Boolean networks with perturbation from sparse gene expression data: a general model applied to the interferon regulatory network

scientific article

Inhibition of the association of RNA polymerase II with the preinitiation complex by a viral transcriptional repressor

scientific article published on March 1996

Inhibition of the stress-activated kinase, p38, does not affect the virus transcriptional program of herpes simplex virus type 1.

scientific article published in November 2004

Interferon Control of the Sterol Metabolic Network: Bidirectional Molecular Circuitry-Mediating Host Protection

scientific article published on 23 December 2016

Is systems pharmacology ready to impact upon therapy development? A study on the cholesterol biosynthesis pathway

scientific article published on 14 September 2017

Locus-specific gene expression pattern suggests a unique propagation strategy for a giant algal virus

scientific article published in August 2006

Lymphotoxins and cytomegalovirus cooperatively induce interferon-beta, establishing host-virus détente.

scientific article published in October 2001

Meta-Analysis Identification of Highly Robust and Differential Immune-Metabolic Signatures of Systemic Host Response to Acute and Latent Tuberculosis in Children and Adults

scientific article published on 04 October 2018

Microbial exposure drives polyclonal expansion of innate γδ T cells immediately after birth

scientific article published on 20 July 2020

Modelling non-stationary gene regulatory processes with a non-homogeneous Bayesian network and the allocation sampler

article

Modelling of macrophage gene expression in the interferon pathway

article

Molecular profiling of the human testis reveals stringent pathway-specific regulation of RNA expression following gonadotropin suppression and progestogen treatment.

scientific article published on 26 December 2007

Molecular recognition with DNA nanoswitches: effects of single base mutations on structure

scientific article

Multi-factorial analysis of class prediction error: estimating optimal number of biomarkers for various classification rules

scientific article

Multiple sequence-specific transcription factors modulate cytomegalovirus enhancer activity in vitro.

scientific article published on April 1988

Neutrality of the canonical NF-kappaB-dependent pathway for human and murine cytomegalovirus transcription and replication in vitro

scientific article published on January 2004

Optimization of a parallel permutation testing function for the SPRINT R package

scientific article published on 23 June 2011

Oxylipin metabolism is controlled by mitochondrial β-oxidation during bacterial inflammation

scientific article published on 10 January 2022

PDQ Wizard: automated prioritization and characterization of gene and protein lists using biomedical literature

scientific article published on 29 June 2006

PEDRo: a database for storing, searching and disseminating experimental proteomics data

scientific article

Parallel classification and feature selection in microarray data using SPRINT.

scientific article

Peptide-tags for enhanced DNA microarray performance

scientific article

Positional characteristics of fluorophores influencing signal output of a DNA nanoswitch

Promoting coherent minimum reporting guidelines for biological and biomedical investigations: the MIBBI project

scientific article (publication date: August 2008)

Prostaglandin E₂ constrains systemic inflammation through an innate lymphoid cell-IL-22 axis

scientific article published on March 2016

Pulmonary epithelial barrier and immunological functions at birth and in early life - key determinants of the development of asthma? A description of the protocol for the Breathing Together study

article

Purine metabolism controls innate lymphoid cell function and protects against intestinal injury.

scientific article

Quantitative assessment of human whole blood RNA as a potential biomarker for infectious disease

scientific article

Quantitative comparison of the HSV-1 and HSV-2 transcriptomes using DNA microarray analysis.

scientific article published on 31 January 2006

Rapid antibody responses by low-dose, single-step, dendritic cell-targeted immunization

scientific article

Rapid proteasomal elimination of 3-hydroxy-3-methylglutaryl-CoA reductase by interferon-γ in primary macrophages requires endogenous 25-hydroxycholesterol synthesis

scientific article published on 7 March 2015

Recognition of DNA by Synthetic Antibodies

scientific article published in 1994

Regulation of the transcription and replication cycle of human cytomegalovirus is insensitive to genetic elimination of the cognate NF-kappaB binding sites in the enhancer

scientific article published on October 2006

Reversible inhibition of murine cytomegalovirus replication by gamma interferon (IFN-γ) in primary macrophages involves a primed type I IFN-signaling subnetwork for full establishment of an immediate-early antiviral state

scientific article

SPRINT: a new parallel framework for R.

scientific article

STAT2 deficiency and susceptibility to viral illness in humans

scientific journal article

Sex-Differential Non-Vaccine-Specific Immunological Effects of Diphtheria-Tetanus-Pertussis and Measles Vaccination

scientific article

Solution state hybridization detection using time-resolved fluorescence anisotropy of quantum dot-DNA bioconjugates

Statistical methods for analysis of high-throughput RNA interference screens

scientific article

Steroid signalling in human ovarian surface epithelial cells: the response to interleukin-1alpha determined by microarray analysis.

scientific article

Synaptic NMDA receptor activity boosts intrinsic antioxidant defenses

scientific article published on 23 March 2008

Temporal profiling of the coding and noncoding murine cytomegalovirus transcriptomes

scientific article published on 6 April 2011

The Pathway Editor: A tool for managing complex biological networks

The activator protein 1 binding motifs within the human cytomegalovirus major immediate-early enhancer are functionally redundant and act in a cooperative manner with the NF-{kappa}B sites during acute infection

scientific article published on 24 November 2010

The mEPN scheme: an intuitive and flexible graphical system for rendering biological pathways

scientific article

The mouse cytomegalovirus immediate-early 1 gene is not required for establishment of latency or for reactivation in the lungs

scientific article published on 11 February 2009

The neonatal window of opportunity-early priming for life.

scientific article published on 13 December 2017

The stability and characteristics of a DNA Holliday junction switch

article

The transcription factor STAT-1 couples macrophage synthesis of 25-hydroxycholesterol to the interferon antiviral response

scientific article published on 27 December 2012

Time-Resolved FRET and FLIM of Four-way DNA Junctions

scientific article published on 22 September 2006

Time-lapse ultrashort pulse microscopy of infection in three-dimensional versus two-dimensional culture environments reveals enhanced extra-chromosomal virus replication compartment formation

scientific article published on March 2013

Transcriptional responses of murine macrophages to the adenylate cyclase toxin of Bordetella pertussis

scientific article published on 14 August 2007

Transcriptomal analysis of varicella-zoster virus infection using long oligonucleotide-based microarrays

scientific article published on October 2005

Transcriptome profile of murine gammaherpesvirus-68 lytic infection

scientific article published in January 2003

Transplantation of a 17-amino acid alpha-helical DNA-binding domain into an antibody molecule confers sequence-dependent DNA recognition

scientific article

Uterine NK cells regulate endometrial bleeding in women and are suppressed by the progesterone receptor modulator asoprisnil

scientific article published on 02 August 2013

Viral enhancer mimicry of host innate-immune promoters

scientific article

Viral mediated redirection of NEMO/IKKγ to autophagosomes curtails the inflammatory cascade

scientific article published on 2 February 2012

Whole blood gene expression profiling of neonates with confirmed bacterial sepsis

scientific article

Paulina is supported by:

About Paulina

Help