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List of works by Jesus Gil

A genetic screen identifies topoisomerase 1 as a regulator of senescence.

scientific article

A high glycolytic flux supports the proliferative potential of murine embryonic stem cells

scientific article published on 01 March 2007

AP-1 imprints a reversible transcriptional programme of senescent cells

scientific article published on 08 June 2020

Ageing as developmental decay: insights from p16(INK4a.).

scientific article

An Epigenetic Switch: From Senescent Melanocytes to Malignant Melanoma (and Back).

scientific article published in February 2018

An adaptive signaling network in melanoma inflammatory niches confers tolerance to MAPK signaling inhibition

scientific article

Anti-apoptotic and oncogenic properties of the dsRNA-binding protein of vaccinia virus, E3L.

scientific article published on December 2002

Author Correction: AP-1 imprints a reversible transcriptional programme of senescent cells

scientific article published on 16 September 2020

Author Correction: P53 and mTOR signalling determine fitness selection through cell competition during early mouse embryonic development

scientific article published in Nature Communications

Blunting senescence boosts liver regeneration

scientific article published on 01 April 2020

CBX7 and miR-9 are part of an autoregulatory loop controlling p16(INK) (4a).

scientific article published on 29 September 2015

CBX7 controls the growth of normal and tumor-derived prostate cells by repressing the Ink4a/Arf locus.

scientific article

Caspase 9 activation by the dsRNA-dependent protein kinase, PKR: molecular mechanism and relevance.

scientific article published in October 2002

Cellular senescence causes ageing

scientific article published on 01 July 2019

Chemokine signaling via the CXCR2 receptor reinforces senescence

scientific article

Co-regulation of senescence-associated genes by oncogenic homeobox proteins and polycomb repressive complexes

scientific article published on July 2013

Controlling secretion to limit chemoresistance.

scientific article published on August 2016

Coupling shRNA screens with single-cell RNA-seq identifies a dual role for mTOR in reprogramming-induced senescence.

scientific article published on 14 November 2017

Cyclin-dependent kinase inhibitor p21 controls adult neural stem cell expansion by regulating Sox2 gene expression

scientific article published on 20 December 2012

DGCR8-mediated disruption of miRNA biogenesis induces cellular senescence in primary fibroblasts.

scientific article published on 19 July 2013

Epigenetic regulation of the INK4b-ARF-INK4a locus: in sickness and in health

scientific article

Functional crosstalk between Bmi1 and MLL/Hoxa9 axis in establishment of normal hematopoietic and leukemic stem cells

scientific article published on 01 June 2011

Galactose-modified duocarmycin prodrugs as senolytics

scientific article published on 16 March 2020

HMGB2 holds the key to the senescence-associated secretory phenotype

scientific article published on 31 October 2016

IMR90 ER:RAS: A Cell Model of Oncogene-Induced Senescence

scientific article published on 01 January 2019

Identification of functional domains of the interferon-induced enzyme PKR in cells lacking endogenous PKR.

scientific article published on November 1999

Immortalization of primary human prostate epithelial cells by c-Myc.

scientific article

Immunization with recombinant DNA and modified vaccinia virus Ankara (MVA) vectors delivering PSCA and STEAP1 antigens inhibits prostate cancer progression.

scientific article published on 21 December 2010

In vivo regulation of protein synthesis by phosphorylation of the alpha subunit of wheat eukaryotic initiation factor 2

scientific article published on 01 June 2000

Induction of fibroblast senescence generates a non-fibrogenic myofibroblast phenotype that differentially impacts on cancer prognosis

scientific article published on 15 December 2016

Mechanisms and functions of cellular senescence

scientific article published on 2 April 2018

MicroRNA regulation of Cbx7 mediates a switch of Polycomb orthologs during ESC differentiation

scientific article

Mitochondria and senescence: new actors for an old play.

scientific article

Mitochondrial Dysfunction Meets Senescence

scientific article published on 11 February 2016

Mouse polycomb proteins bind differentially to methylated histone H3 and RNA and are enriched in facultative heterochromatin

scientific journal article

Ncoa3 functions as an essential Esrrb coactivator to sustain embryonic stem cell self-renewal and reprogramming

scientific journal article

Oncogenic RAS-induced senescence in human primary thyrocytes: molecular effectors and inflammatory secretome involved.

scientific article published on September 2014

PRC1 complex diversity: where is it taking us?

scientific article

PTBP1-Mediated Alternative Splicing Regulates the Inflammatory Secretome and the Pro-tumorigenic Effects of Senescent Cells

scientific article published on 01 July 2018

Premature senescence in cells from patients with autosomal recessive hypercholesterolemia (ARH): evidence for a role for ARH in mitosis.

scientific article published on 21 July 2011

Primary cilia and senescence: a sensitive issue

scientific article published on January 2014

Prostate carcinogenesis: inflammatory storms

scientific article published on 16 June 2020

Role of polycomb group proteins in stem cell self-renewal and cancer.

scientific article

Role of the chromobox protein CBX7 in lymphomagenesis.

scholarly article

Senescence and aging: Causes, consequences, and therapeutic avenues

scientific article published on 7 November 2017

Senescence as a therapeutically relevant response to CDK4/6 inhibitors

scientific article published on 15 June 2020

Several distinct polycomb complexes regulate and co-localize on the INK4a tumor suppressor locus

scientific article

Stem cell senescence drives age-attenuated induction of pituitary tumours in mouse models of paediatric craniopharyngioma.

scientific article published on 28 November 2017

Synthetic lethal targeting of oncogenic transcription factors in acute leukemia by PARP inhibitors

scientific article published on 23 November 2015

Systems genetics identifies a macrophage cholesterol network associated with physiological wound healing

article

TORn about SASP regulation.

scientific article published on December 2015

TRIM28/KAP1 regulates senescence.

scientific article published on 23 August 2014

The M-type receptor PLA2R regulates senescence through the p53 pathway

scientific article

The catalytic activity of dsRNA-dependent protein kinase, PKR, is required for NF-kappaB activation.

scientific article published in January 2001

The homeoprotein SIX1 controls cellular senescence through the regulation of p16INK4A and differentiation-related genes.

scientific article

The interferon-induced protein kinase (PKR), triggers apoptosis through FADD-mediated activation of caspase 8 in a manner independent of Fas and TNF-alpha receptors.

scientific article published on July 2000

The methyl-CpG-binding protein MECP2 is required for prostate cancer cell growth

scientific article published on 01 March 2006

Tumour compartment transcriptomics demonstrates the activation of inflammatory and odontogenic programmes in human adamantinomatous craniopharyngioma and identifies the MAPK/ERK pathway as a novel therapeutic target

scientific article published on 14 March 2018

Unbiased Characterization of the Senescence-Associated Secretome Using SILAC-Based Quantitative Proteomics

scientific article published on 01 January 2013

Vaccinia Virus E3L Protein Is an Inhibitor of the Interferon (IFN)-Induced 2-5A Synthetase Enzyme

scientific article published on April 10, 1998