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List of works by Christopher A. Cottrell

An HIV-1 antibody from an elite neutralizer implicates the fusion peptide as a site of vulnerability

scientific article

Autologous Antibody Responses to an HIV Envelope Glycan Hole Are Not Easily Broadened in Rabbits

scientific article published on 17 March 2020

Closing and opening holes in the glycan shield of HIV-1 envelope glycoprotein SOSIP trimers can redirect the neutralizing antibody response to the newly unmasked epitopes

article

Conformational Plasticity in the HIV-1 Fusion Peptide Facilitates Recognition by Broadly Neutralizing Antibodies

scientific article published on 01 June 2019

Cryo-EM structure of circumsporozoite protein with a vaccine-elicited antibody is stabilized by somatically mutated inter-Fab contacts

scientific article published on 10 October 2018

Elicitation of Robust Tier 2 Neutralizing Antibody Responses in Nonhuman Primates by HIV Envelope Trimer Immunization Using Optimized Approaches

scientific article

Elicitation of potent serum neutralizing antibody responses in rabbits by immunization with an HIV-1 clade C trimeric Env derived from an Indian elite neutralizer

scientific article published on 07 April 2021

Enhancing and shaping the immunogenicity of native-like HIV-1 envelope trimers with a two-component protein nanoparticle

scientific article published on 19 September 2019

Epitopes for neutralizing antibodies induced by HIV-1 envelope glycoprotein BG505 SOSIP trimers in rabbits and macaques.

scientific article published on 23 February 2018

From structure to sequence: Antibody discovery using cryoEM

scientific article published on 19 January 2022

HIV envelope trimer-elicited autologous neutralizing antibodies bind a region overlapping the N332 glycan supersite

scientific article published on 05 June 2020

Holes in the Glycan Shield of the Native HIV Envelope Are a Target of Trimer-Elicited Neutralizing Antibodies

scientific article published on 17 August 2016

Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.

scientific article published on 14 August 2017

Improving the Immunogenicity of Native-like HIV-1 Envelope Trimers by Hyperstabilization

scientific article

Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates

scientific article published on 31 August 2020

Networks of HIV-1 Envelope Glycans Maintain Antibody Epitopes in the Face of Glycan Additions and Deletions

scientific article published on 12 May 2020

Neutralizing antibody responses induced by HIV-1 envelope glycoprotein SOSIP trimers derived from elite neutralizers

scientific article published on 30 September 2020

Potent anti-influenza H7 human monoclonal antibody induces separation of hemagglutinin receptor-binding head domains

scientific article published on 04 February 2019

Pre-fusion structure of a human coronavirus spike protein.

scientific article

Publisher Correction: Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis

scientific article published in Scientific Reports

Receptor binding and proteolysis do not induce large conformational changes in the SARS-CoV spike

scientific article published on 31 March 2018

Similarities and differences between native HIV-1 envelope glycoprotein trimers and stabilized soluble trimer mimetics

scientific article published on 15 July 2019

Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis

scientific article published in Scientific Reports

Structural and functional evaluation of de novo-designed, two-component nanoparticle carriers for HIV Env trimer immunogens

scientific article published on 11 August 2020

Structural basis of glycan276-dependent recognition by HIV-1 broadly neutralizing antibodies

scientific article published on 01 November 2021

Structure-based design of native-like HIV-1 envelope trimers to silence non-neutralizing epitopes and eliminate CD4 binding.

scientific article published on 21 November 2017

Structures of Ebola virus GP and sGP in complex with therapeutic antibodies

scientific article published on 08 August 2016

Targeting HIV Env immunogens to B cell follicles in nonhuman primates through immune complex or protein nanoparticle formulations

scientific article published on 05 August 2020

Vaccination induces HIV broadly neutralizing antibody precursors in humans ⬇️

journal article published in 2022

Vaccination with Glycan-Modified HIV NFL Envelope Trimer-Liposomes Elicits Broadly Neutralizing Antibodies to Multiple Sites of Vulnerability

scientific article published on 12 November 2019

Vaccine priming of rare HIV broadly neutralizing antibody precursors in nonhuman primates

scientific article published in 2024

Vaccine-Induced Protection from Homologous Tier 2 SHIV Challenge in Nonhuman Primates Depends on Serum-Neutralizing Antibody Titers

scholarly article by Matthias G Pauthner et al published 15 January 2019 in Immunity

Visualization of the HIV-1 Env Glycan Shield Across Scales

scientific article published on 12 November 2019

Visualization of the HIV-1 Env glycan shield across scales

scientific article published on 22 October 2020

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