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List of works by Wu-Chou Su

A Randomized Phase 2 Study Comparing the Combination of Ficlatuzumab and Gefitinib with Gefitinib Alone in Asian Patients with Advanced Stage Pulmonary Adenocarcinoma

scientific article published on 20 July 2016

A multicenter phase II study of biweekly capecitabine in combination with oxaliplatin as first-line chemotherapy in patients with locally advanced or metastatic gastric cancer

scientific article

A multinational phase 2 study of nanoliposomal irinotecan sucrosofate (PEP02, MM-398) for patients with gemcitabine-refractory metastatic pancreatic cancer ⬇️

scientific article published on July 23, 2013

A new photothermal therapeutic agent: core-free nanostructured Au x Ag1-x dendrites

scientific article

A novel derivative of betulinic acid, SYK023, suppresses lung cancer growth and malignancy

scientific article

A polymorphism in the APE1 gene promoter is associated with lung cancer risk

scientific article published on 01 January 2009

AZD9291 in EGFR inhibitor-resistant non-small-cell lung cancer

scientific article

Activity and safety of AZD3759 in EGFR-mutant non-small-cell lung cancer with CNS metastases (BLOOM): a phase 1, open-label, dose-escalation and dose-expansion study

scientific article published on 17 October 2017

Afatinib for patients with lung adenocarcinoma and epidermal growth factor receptor mutations (LUX-Lung 2): a phase 2 trial ⬇️

scientific article published on March 26, 2012

Afatinib versus cisplatin-based chemotherapy for EGFR mutation-positive lung adenocarcinoma (LUX-Lung 3 and LUX-Lung 6): analysis of overall survival data from two randomised, phase 3 trials

scientific article

Afatinib versus placebo for patients with advanced, metastatic non-small-cell lung cancer after failure of erlotinib, gefitinib, or both, and one or two lines of chemotherapy (LUX-Lung 1): a phase 2b/3 randomised trial ⬇️

scientific article published on March 26, 2012

An increase in glucosylceramide synthase induces Bcl-xL-mediated cell survival in vinorelbine-resistant lung adenocarcinoma cells

scientific article

An open, multi-centre, phase II clinical trial to evaluate the efficacy and safety of paclitaxel, UFT, and leucovorin in patients with advanced gastric cancer

scientific article published on 27 June 2006

An open-label safety study of first-line bevacizumab in combination with standard chemotherapy in Chinese patients with metastatic colorectal cancer treated in an expanded access program in Taiwan.

scientific article published on 16 March 2013

An open-label, single-arm, phase 2 trial of the Polo-like kinase inhibitor volasertib (BI 6727) in patients with locally advanced or metastatic urothelial cancer

scientific article

Analysis of heritability and shared heritability based on genome-wide association studies for thirteen cancer types

journal article published in 2015

Annexin A2 silencing induces G2 arrest of non-small cell lung cancer cells through p53-dependent and -independent mechanisms.

scientific article published on 2 August 2012

Antibody-free isolation of rare cancer cells from blood based on 3D lateral dielectrophoresis.

scientific article published in June 2015

Autocrine IL-6-induced Stat3 activation contributes to the pathogenesis of lung adenocarcinoma and malignant pleural effusion.

scientific article published on 6 March 2006

Betulinic Acid Decreases Specificity Protein 1 (Sp1) Level via Increasing the Sumoylation of Sp1 to Inhibit Lung Cancer Growth ⬇️

scientific article published on September 5, 2012

Bevacizumab with erlotinib as first-line therapy in Asian patients with advanced hepatocellular carcinoma: a multicenter phase II study

scientific article

CDKN1A-mediated responsiveness of MLL-AF4-positive acute lymphoblastic leukemia to Aurora kinase-A inhibitors.

scientific article published on 13 January 2014

Cabozantinib in hepatocellular carcinoma: results of a phase 2 placebo-controlled randomized discontinuation study

scientific article

Chemotherapy with cisplatin and continuous infusion of 5-fluorouracil and bleomycin for recurrent and metastatic nasopharyngeal carcinoma in Taiwan

scientific article published on 01 July 1993

Circulating interleukin-6 level is a prognostic marker for survival in advanced nonsmall cell lung cancer patients treated with chemotherapy.

scientific article published on 29 October 2012

Comparison of expected health impacts for major cancers: integration of incidence rate and loss of quality-adjusted life expectancy

scientific article published on 30 December 2014

Constitutive STAT5 activation correlates with better survival in cervical cancer patients treated with radiation therapy

scientific article published on 06 February 2011

Constitutive activation of STAT3 and STAT5 is present in the majority of nasopharyngeal carcinoma and correlates with better prognosis

scientific article published on July 2003

Cost effectiveness of cancer treatment in Taiwan

scientific article published on 11 June 2016

Cost-effectiveness of implementing computed tomography screening for lung cancer in Taiwan.

scientific article published on 04 April 2017

Cytomegalovirus-related neutropenic enterocolitis with negative CMV antigenemia as the initial presentation in an acute myeloid leukemia patient

scientific article published on 29 August 2008

Dynamic changes in quality of life after three first-line therapies for EGFR mutation-positive advanced non-small-cell lung cancer

scientific article published on 5 February 2018

Dysregulation of Rab37-Mediated Cross-talk between Cancer Cells and Endothelial Cells via Thrombospondin-1 Promotes Tumor Neovasculature and Metastasis

scientific article published on 15 November 2016

EGF-mediated inhibition of ubiquitin-specific peptidase 24 expression has a crucial role in tumorigenesis

scientific article

EGFR exon 19 in‐frame deletion and polymorphisms of DNA repair genes in never‐smoking female lung adenocarcinoma patients ⬇️

scientific article published on June 28, 2012

Elevated BCRP/ABCG2 expression confers acquired resistance to gefitinib in wild-type EGFR-expressing cells

scientific article

Elucidating Quantum Confinement in Graphene Oxide Dots Based On Excitation-Wavelength-Independent Photoluminescence.

scientific article published on 18 May 2016

Emerging platforms using liquid biopsy to detect EGFR mutations in lung cancer

scientific article

Epidermal Growth Factor Receptor Mutation and Anaplastic Lymphoma Kinase Gene Fusion: Detection in Malignant Pleural Effusion by RNA or PNA Analysis.

scientific article

Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor Treatment Response in Advanced Lung Adenocarcinomas with G719X/L861Q/S768I Mutations.

scientific article published on May 2015

Epidermal growth factor receptor mutation status in stage I lung adenocarcinoma with different image patterns.

scientific article published on June 2011

Epidermal growth factor-activated aryl hydrocarbon receptor nuclear translocator/HIF-1{beta} signal pathway up-regulates cyclooxygenase-2 gene expression associated with squamous cell carcinoma

scientific article published on 09 February 2009

Estimating the lifelong health impact and financial burdens of different types of lung cancer

scientific article

Estimation of loss of quality-adjusted life expectancy (QALE) for patients with operable versus inoperable lung cancer: adjusting quality-of-life and lead-time bias for utility of surgery.

scientific article published on 18 August 2014

Estrogen Receptor Gene Polymorphisms and Lung Adenocarcinoma Risk in Never-Smoking Women

scientific article published on 21 August 2015

Expression of S100A4 and Met: potential predictors for metastasis and survival in early-stage breast cancer.

scientific article published in January 2004

Expression of fibroblast growth factor-1 and fibroblast growth factor-2 in normal liver and hepatocellular carcinoma

scientific article published on 01 October 1998

Expression of oncogene products HER2/Neu and Ras and fibrosis-related growth factors bFGF, TGF-beta, and PDGF in bile from biliary malignancies and inflammatory disorders.

scientific article published in July 2001

Gastric perforation secondary to regression of lung adenocarcinoma after gefitinib treatment.

scientific article published on 19 November 2012

Genome-Wide Association Study of Genetic Predictors of Overall Survival for Non–Small Cell Lung Cancer in Never Smokers ⬇️

scientific article published on May 23, 2013

Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia

scientific journal article

Germ cell tumor with somatic-type malignancy presenting as right facial swelling in a young woman

scientific article published on 05 July 2011

Global Oct4 target gene analysis reveals novel downstream PTEN and TNC genes required for drug-resistance and metastasis in lung cancer

scientific article

Health-related quality of life after first-line anti-cancer treatments for advanced non-small cell lung cancer in clinical practice.

scientific article published on 7 November 2015

High-dose chemotherapy and hematopoietic stem cell transplantation for patients with nasopharyngeal cancer: a feasibility study

scientific article published on 01 July 2003

Hormone replacement therapy and lung cancer risk in Chinese.

scientific article published in October 2007

Hypoxia and metabolic phenotypes during breast carcinogenesis: expression of HIF-1alpha, GLUT1, and CAIX.

scientific article

Hypoxia-inducible factor-1alpha correlates with MET and metastasis in node-negative breast cancer

scientific article published on 21 September 2006

Implantable venous port-related infections in cancer patients.

scientific article published on 16 January 2004

Imputation and subset-based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p15.33

journal article published in 2014

Incidence and predictors of anticipatory nausea and vomiting in Asia Pacific clinical practice--a longitudinal analysis.

scientific article published on 13 August 2014

Increased expression of nitric oxide synthase and cyclooxygenase-2 is associated with poor survival in cervical cancer treated with radiotherapy.

scientific article published on 15 August 2005

Inhibiting glucosylceramide synthase facilitates the radiosensitizing effects of vinorelbine in lung adenocarcinoma cells

scientific article published on 13 April 2014

Interactions between household air pollution and GWAS-identified lung cancer susceptibility markers in the Female Lung Cancer Consortium in Asia (FLCCA).

scientific article published on 8 January 2015

Liquid biopsy genotyping in lung cancer: ready for clinical utility?

scientific article

Long-term results of a phase II trial with frontline concurrent chemoradiotherapy followed by consolidation chemotherapy for localized nasal natural killer/T-cell lymphoma

scientific article published on 10 October 2014

Low incidence of thromboembolism in relapsed/refractory myeloma patients treated with thalidomide without thromboprophylaxis in Taiwan ⬇️

scientific article published on June 17, 2012

MMP7-mediated cleavage of nucleolin at Asp255 induces MMP9 expression to promote tumor malignancy

scientific article published on 17 March 2014

Meta-analysis of genome-wide association studies identifies multiple lung cancer susceptibility loci in never-smoking Asian women

scientific article

Modulation of Biomarker Expression by Osimertinib: Results of the Paired Tumor Biopsy Cohorts of the AURA Phase I Trial

scientific article published on 24 July 2017

Near-diploid transitional cell carcinoma: a preliminary report

scientific article published on 01 January 1994

Noninvasive saliva-based EGFR gene mutation detection in patients with lung cancer.

scientific article

Novel arylhydrazone-conjugated gold nanoparticles with DNA-cleaving ability: the first DNA-nicking nanomaterial

scientific article published on 23 October 2007

Nucleocytoplasmic transport blockage by SV40 peptide-modified gold nanoparticles induces cellular autophagy

scientific article published on 8 October 2012

Nucleolin regulates c-Jun/Sp1-dependent transcriptional activation of cPLA2alpha in phorbol ester-treated non-small cell lung cancer A549 cells

scientific article

Oncoprotein ZNF322A transcriptionally deregulates alpha-adducin, cyclin D1 and p53 to promote tumor growth and metastasis in lung cancer

scientific article published on 17 August 2015

Osimertinib in Pretreated T790M-Positive Advanced Non-Small-Cell Lung Cancer: AURA Study Phase II Extension Component

scientific article

Osimertinib in Untreated EGFR-Mutated Advanced Non-Small-Cell Lung Cancer

scientific article published on 18 November 2017

Phase 2 trial of afatinib, an ErbB family blocker, in solid tumors genetically screened for target activation.

scientific article published on 14 June 2013

Phase II Multicentered Study of Low-Dose Everolimus plus Cisplatin and Weekly 24-Hour Infusion of High-Dose 5-Fluorouracil and Leucovorin as First-Line Treatment for Patients with Advanced Gastric Cancer

Phase II evaluation of LY2603618, a first-generation CHK1 inhibitor, in combination with pemetrexed in patients with advanced or metastatic non-small cell lung cancer.

scientific article published on 27 June 2016

Phase III study of afatinib or cisplatin plus pemetrexed in patients with metastatic lung adenocarcinoma with EGFR mutations.

scientific article

Positive feedback regulation between IL10 and EGFR promotes lung cancer formation

scientific article published on 03 March 2016

Predictive and prognostic value of human copper transporter 1 (hCtr1) in patients with stage III non-small-cell lung cancer receiving first-line platinum-based doublet chemotherapy ⬇️

scientific article published on July 23, 2011

Preemptive use of interferon or lamivudine for hepatitis B reactivation in patients with aggressive lymphoma receiving chemotherapy.

scientific article published on 5 December 2003

Prognostic Value of Whole-Body Total Lesion Glycolysis at Pretreatment FDG PET/CT in Non–Small Cell Lung Cancer ⬇️

scientific article published on June 12, 2012

Prognostic significance of co-expression of RON and MET receptors in node-negative breast cancer patients.

scientific article

Proteomic analysis of human pleural effusion

scientific article published on 01 March 2005

Proteomic profiling of human pleural effusion using two-dimensional nano liquid chromatography tandem mass spectrometry

scientific article published on 01 July 2005

Randomised clinical trial: comparison of two everolimus dosing schedules in patients with advanced hepatocellular carcinoma.

scientific article

Rapid engraftment of mast cells of donor origin in a case of acute myeloid leukemia with mast cell leukemia after allogeneic stem cell transplantation

scientific article published on 01 July 2003

Rasch models suggested the satisfactory psychometric properties of the World Health Organization Quality of Life-Brief among lung cancer patients.

scientific article published on 8 September 2015

Risk factors for primary lung cancer among never smokers by gender in a matched case-control study.

scientific article published on 22 May 2012

STAT1 activation by venous malformations mutant Tie2-R849W antagonizes VEGF-A-mediated angiogenic response partly via reduced bFGF production ⬇️

scientific article published on October 21, 2012

Safety and Efficacy of Buparlisib (BKM120) in Patients with PI3K Pathway-Activated Non-Small Cell Lung Cancer: Results from the Phase II BASALT-1 Study

scientific article

Signal transducer and activator of transcription 3 activation up-regulates interleukin-6 autocrine production: a biochemical and genetic study of established cancer cell lines and clinical isolated human cancer cells.

scientific article

Sp1 expression regulates lung tumor progression.

scientific article

Sp1-mediated microRNA-182 expression regulates lung cancer progression.

scientific article published on February 2014

Successful AZD9291 Therapy in Advanced Non-Small Cell Lung Cancer after Failure of HM61713

scientific article published on 01 June 2017

Successful matched-unrelated bone marrow transplantation in a patient with beta-thalassemia major

scientific article published on 01 October 2002

Surfactant-assisted hollowing of Cu nanoparticles involving halide-induced corrosion-oxidation processes

scientific article published on 01 May 2006

Syntheses of Platinum-Sulindac Complexes and Their Nanoparticles as Targeted Anticancer Drugs.

scientific article published on 11 January 2016

Targeted Paclitaxel by conjugation to iron oxide and gold nanoparticles.

scientific article

The Emergent Landscape of Detecting EGFR Mutations Using Circulating Tumor DNA in Lung Cancer.

scientific article

The c.1085A>G Genetic Variant of CSF1R Gene Regulates Tumor Immunity by Altering the Proliferation, Polarization, and Function of Macrophages

scientific article published on 19 July 2017

The down regulation of target genes by photo activated DNA nanoscissors.

scientific article

The expression and prognostic significance of platelet-derived growth factor receptor alpha in mature T- and natural killer-cell lymphomas

scientific article published on 17 July 2008

The impact of EGFR mutations on the incidence and survival of stages I to III NSCLC patients with subsequent brain metastasis

scientific article published on 15 February 2018

The increment in standardized uptake value determined using dual-phase 18F-FDG PET is a promising prognostic factor in non-small-cell lung cancer.

scientific article published on 7 June 2013

Triweekly reduced-dose docetaxel combined with cisplatin in recurrent/metastatic head and neck squamous cell carcinoma: a multicenter phase II study.

scientific article published on 12 April 2011

Upregulation of tissue factor by activated Stat3 contributes to malignant pleural effusion generation via enhancing tumor metastasis and vascular permeability in lung adenocarcinoma

scientific article

Variants of ubiquitin-specific peptidase 24 play a crucial role in lung cancer malignancy

scientific article

Vinca alkaloids cause aberrant ROS-mediated JNK activation, Mcl-1 downregulation, DNA damage, mitochondrial dysfunction, and apoptosis in lung adenocarcinoma cells ⬇️

scientific article published on January 20, 2012

Vinflunine-gemcitabine versus vinflunine-carboplatin as first-line chemotherapy in cisplatin-unfit patients with advanced urothelial carcinoma: results of an international randomized phase II trial (JASINT1)

scientific article published on 16 December 2015

Water-Dissolvable Sodium Sulfate Nanowires as a Versatile Template for the Fabrication of Polyelectrolyte- and Metal-Based Nanotubes

scientific article published on 01 September 2006

Wheat germ agglutinin-induced paraptosis-like cell death and protective autophagy is mediated by autophagy-linked FYVE inhibition

scientific article published on 24 August 2017

p53 and c-erbB-2 but not bcl-2 are predictive of metastasis-free survival in breast cancer patients receiving post-mastectomy adjuvant radiotherapy in Taiwan

scientific article published on 01 September 2002

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