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List of works by Theodore P Nicolaides

A Kinase Inhibitor Targeted to mTORC1 Drives Regression in Glioblastoma.

scientific article published on March 2017

A dual phosphoinositide-3-kinase alpha/mTOR inhibitor cooperates with blockade of epidermal growth factor receptor in PTEN-mutant glioma

scientific article published on September 2007

Acquired resistance to BRAF inhibition in BRAFV600E mutant gliomas

scientific article published on 07 September 2016

Activating NRF1-BRAF and ATG7-RAF1 fusions in anaplastic pleomorphic xanthoastrocytoma without BRAF p.V600E mutation

scientific article

Bromodomain Inhibitor Review: Bromodomain and Extra-terminal Family Protein Inhibitors as a Potential New Therapy in Central Nervous System Tumors

scientific article

Cell surface Notch ligand DLL3 is a therapeutic target in isocitrate dehydrogenase mutant glioma

scientific article published on 05 November 2018

Characterization of a diffuse intrinsic pontine glioma cell line: implications for future investigations and treatment ⬇️

scientific article published on September 17, 2012

Combined BRAFV600E and MEK blockade for BRAFV600E-mutant gliomas.

scientific article published on 15 November 2016

Concurrent MEK targeted therapy prevents MAPK pathway reactivation during BRAFV600E targeted inhibition in a novel syngeneic murine glioma model

scientific article published on 03 October 2016

Cooperative interactions of BRAF V600E kinase and CDKN2A locus deficiency in pediatric malignant astrocytoma as a basis for rational therapy ⬇️

scientific article published on May 14, 2012

Deep sequencing of WNT-activated medulloblastomas reveals secondary SHH pathway activation.

scientific article published on 12 February 2018

Delayed Fluorodeoxyglucose Positron Emission Tomography Imaging in the Differentiation of Tumor Recurrence and Radiation Necrosis in Pediatric Central Nervous System Tumors: Case Report and Review of the Literature

scientific article published on 26 September 2018

Driving Neuronal Differentiation through Reversal of an ERK1/2-miR-124-SOX9 Axis Abrogates Glioblastoma Aggressiveness

scientific article published on 01 August 2019

EGFR blockade prevents glioma escape from BRAFV600E targeted therapy

scientific article

Erratum to: Survival advantage combining a BRAF inhibitor and radiation in BRAF V600E-mutant glioma.

scientific article

Evaluation of Three Morphologically Distinct Virus-Like Particles as Nanocarriers for Convection-Enhanced Drug Delivery to Glioblastoma

Feasibility, safety, and indications for surgical biopsy of intrinsic brainstem tumors in children.

scientific article

High-dose chemotherapy with autologous stem-cell rescue in the treatment of patients with recurrent non-cerebellar primitive neuroectodermal tumors.

scientific article published in March 2004

Inhibiting 4EBP1 in glioblastoma.

scientific article

Intratumoral therapy of glioblastoma multiforme using genetically engineered transferrin for drug delivery.

scientific article

Kinetics of inhibitor cycling underlie therapeutic disparities between EGFR-driven lung and brain cancers

scientific article published on 31 March 2012

Mechanisms of Resistance to EGFR Inhibition Reveal Metabolic Vulnerabilities in Human GBM

scientific article published on 03 July 2019

Metastatic Diffuse Intrinsic Pontine Glioma to the Peritoneal Cavity Via Ventriculoperitoneal Shunt: Case Report and Literature Review

scientific article published on 27 April 2015

Metastatic clival chordoma: a case report of multiple extraneural metastases following resection and proton beam radiotherapy in a 5-year old boy.

scientific article

Molecular profiling and targeted therapy in pediatric gliomas: review and consensus recommendations

scientific article published on 26 February 2019

NT113, a pan-ERBB inhibitor with high brain penetrance, inhibits the growth of glioblastoma xenografts with EGFR amplification

scientific article

Precision knockdown of EGFR gene expression using radio frequency electromagnetic energy.

scientific article published on 22 April 2017

Pure germinomas of the central nervous system: treatment strategies and outcomes

scientific article

Reirradiation and PD-1 inhibition with nivolumab for the treatment of recurrent diffuse intrinsic pontine glioma: a single-institution experience

scientific article published on 11 September 2018

Suprasellar Germinoma Presenting with Slipped Capital Femoral Epiphysis: Case Report.

scientific article published on 16 December 2017

Surveillance Screening in Li-Fraumeni Syndrome: Raising Awareness of False Positives.

scientific article

Survival advantage combining a BRAF inhibitor and radiation in BRAF V600E-mutant glioma

scientific article published on 18 September 2015

Targeted next-generation sequencing of pediatric neuro-oncology patients improves diagnosis, identifies pathogenic germline mutations, and directs targeted therapy.

scientific article

Targeted therapy for BRAFV600E malignant astrocytoma.

scientific article published on 28 October 2011

Targeting a Plk1-Controlled Polarity Checkpoint in Therapy-Resistant Glioblastoma-Propagating Cells

scientific article

The genetic landscape of anaplastic pleomorphic xanthoastrocytoma

scientific article published on 06 November 2018

Therapeutic and Prognostic Implications of BRAF V600E in Pediatric Low-Grade Gliomas

scientific article published on 20 July 2017

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