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List of works by Massimo Squatrito

53BP1 is a haploinsufficient tumor suppressor and protects cells from radiation response in glioma

scientific article published on 21 August 2012

A kinase-deficient NTRK2 splice variant predominates in glioma and amplifies several oncogenic signaling pathways

scientific article published on 12 June 2020

An essential role for p38 MAPK in cerebellar granule neuron precursor proliferation

scientific article published on April 2012

Astrocyte-specific expression patterns associated with the PDGF-induced glioma microenvironment.

scientific article

DNA damage response and growth factor signaling pathways in gliomagenesis and therapeutic resistance

scientific article

Defective DNA double-strand break repair underlies enhanced tumorigenesis and chromosomal instability in p27-deficient mice with growth factor-induced oligodendrogliomas.

scientific article

Dual mode of degradation of Cdc25 A phosphatase

scientific article

EBP1 is a nucleolar growth-regulating protein that is part of pre-ribosomal ribonucleoprotein complexes

scientific article

EGFR feedback-inhibition by Ran-binding protein 6 is disrupted in cancer

scientific article

Ebp1 is a dsRNA-binding protein associated with ribosomes that modulates eIF2alpha phosphorylation.

scientific article

GlioVis data portal for visualization and analysis of brain tumor expression datasets

scientific article published on 9 November 2016

Glioblastoma and glioblastoma stem cells are dependent on functional MTH1.

scientific article published on 20 July 2017

Histone acetyltransferase PCAF is required for Hedgehog-Gli-dependent transcription and cancer cell proliferation

scientific article published on 13 August 2013

Influenza virus infection causes global RNAPII termination defects

Inhibition of TRF1 Telomere Protein Impairs Tumor Initiation and Progression in Glioblastoma Mouse Models and Patient-Derived Xenografts

scientific article published in November 2017

LIF regulates CXCL9 in tumor-associated macrophages and prevents CD8+ T cell tumor-infiltration impairing anti-PD1 therapy

scientific article published on 11 June 2019

Loss of ATM/Chk2/p53 pathway components accelerates tumor development and contributes to radiation resistance in gliomas

scientific article published on December 2010

MEF promotes stemness in the pathogenesis of gliomas

scientific article published on December 2012

MGMT genomic rearrangements contribute to chemotherapy resistance in gliomas

scientific article published on 04 August 2020

Most human non-GCIMP glioblastoma subtypes evolve from a common proneural-like precursor glioma

scientific article

Oncogenic YAP promotes radioresistance and genomic instability in medulloblastoma through IGF2-mediated Akt activation

scientific article published on 29 August 2011

PDGFRA gene rearrangements are frequent genetic events in PDGFRA-amplified glioblastomas

scientific article

Perivascular nitric oxide activates notch signaling and promotes stem-like character in PDGF-induced glioma cells

scientific article

Radiation resistance and stem-like cells in brain tumors.

scientific article published in December 2006

Somatic genome editing with the RCAS-TVA-CRISPR-Cas9 system for precision tumor modeling

scientific article published on 13 April 2018

Splicing factor hnRNPH drives an oncogenic splicing switch in gliomas

scientific article

TMIC-22. DECIPHERING GLIOMA INTRINSIC TRANSCRIPTIONAL SUBTYPES IDENTIFIES TUMOR EVOLUTION ASSOCIATES WITH CHANGES IN IMMUNE-MICROENVIRONMENT

scientific article published on 6 November 2017

Take It Down a NOTCH in Forebrain Tumors.

scientific article published in December 2015

Targeting MT1-MMP as an ImmunoPET-Based Strategy for Imaging Gliomas

scientific article

Tip60 in DNA damage response and growth control: many tricks in one HAT.

scientific article published on 9 August 2006

Tip60 is a haplo-insufficient tumour suppressor required for an oncogene-induced DNA damage response

scientific article published in Nature

Tumor Evolution of Glioma-Intrinsic Gene Expression Subtypes Associates with Immunological Changes in the Microenvironment.

scientific article published in July 2017

Tumor Evolution of Glioma-Intrinsic Gene Expression Subtypes Associates with Immunological Changes in the Microenvironment.

scientific article