List of works - Peter Vogel

A Perfect Storm: Increased Colonization and Failure of Vaccination Leads to Severe Secondary Bacterial Infection in Influenza Virus-Infected Obese Mice

scientific article published on 19 September 2017

A Single Point Mutation (Y89F) within the Non-Structural Protein 1 of Influenza A Viruses Limits Epithelial Cell Tropism and Virulence in Mice

article by Eike R. Hrincius et al published June 2012 in The American Journal of Pathology

A live-attenuated pneumococcal vaccine elicits CD4+ T-cell dependent class switching and provides serotype independent protection against acute otitis media

scientific article published on January 2014

A mouse model of hereditary folate malabsorption: deletion of the PCFT gene leads to systemic folate deficiency.

scientific article

A novel cytotoxic sequence contributes to influenza A viral protein PB1-F2 pathogenicity and predisposition to secondary bacterial infection

scientific article published on 30 October 2013

ASK Family Kinases Are Required for Optimal NLRP3 Inflammasome Priming

scientific article published on 15 January 2018

Abcb11 deficiency induces cholestasis coupled to impaired β-fatty acid oxidation in mice

scientific article

Acute Lung Injury Results from Innate Sensing of Viruses by an ER Stress Pathway

scientific article

Aerosolized specific antibody protects mice from lung injury associated with aerosolized ricin exposure

scientific article published on 01 September 1996

Allergic inflammation alters the lung microbiome and hinders synergistic co-infection with H1N1 influenza virus and Streptococcus pneumoniae in C57BL/6 mice

scientific article published on 18 December 2019

An NLRP3 inflammasome-triggered Th2-biased adaptive immune response promotes leishmaniasis

scientific article

Antibody-secreting cells in respiratory tract tissues in the absence of eosinophils as supportive partners

scientific article published on 18 July 2016

Astrovirus infects actively secreting goblet cells and alters the gut mucus barrier

scientific article published on 29 April 2020

Autophagy enforces functional integrity of regulatory T cells by coupling environmental cues and metabolic homeostasis

scientific article published on 25 January 2016

CRISPR screens unveil signal hubs for nutrient licensing of T cell immunity

scientific article published on 18 November 2021

Cardiomyopathy associated with angiomatous pheochromocytoma in a rhesus macaque (Macaca mulatta).

scientific article published in July 2003

Characterization of a multicopy family of genes encoding a surface-expressed serine endoprotease in rat Pneumocystis carinii

scientific article published on 01 July 1999

Comparative neurovirulence and tissue tropism of wild-type and attenuated strains of Venezuelan equine encephalitis virus administered by aerosol in C3H/HeN and BALB/c mice.

scientific article published in September 1998

Comparative pathology of murine mucolipidosis types II and IIIC

scientific article

Competitive Fitness of Influenza B Viruses Possessing E119A and H274Y Neuraminidase Inhibitor Resistance-Associated Substitutions in Ferrets

scientific article

Compromised respiratory function in lethal influenza infection is characterized by the depletion of type I alveolar epithelial cells beyond threshold levels

scientific article published on 25 January 2013

Concerted activation of the AIM2 and NLRP3 inflammasomes orchestrates host protection against Aspergillus infection

scientific article

Congenital hydrocephalus in genetically engineered mice

scientific journal article

Critical Role for the DNA Sensor AIM2 in Stem Cell Proliferation and Cancer

scientific article published on 18 June 2015

Critical roles of mTORC1 signaling and metabolic reprogramming for M-CSF-mediated myelopoiesis.

scientific article published on 7 August 2017

Cryptogenic organizing pneumonia in Tomm5(-/-) mice

scientific article published on 11 June 2012

Cutting edge: STING mediates protection against colorectal tumorigenesis by governing the magnitude of intestinal inflammation

scientific article

DAI Senses Influenza A Virus Genomic RNA and Activates RIPK3-Dependent Cell Death

scientific article

DOCK2 confers immunity and intestinal colonization resistance to Citrobacter rodentium infection

scientific article published on 13 June 2016

Data from CAR T-cell Design-dependent Remodeling of the Brain Tumor Immune Microenvironment Modulates Tumor-associated Macrophages and Anti-glioma Activity

Determination of the virulence of the pigmentation-deficient and pigmentation-/plasminogen activator-deficient strains of Yersinia pestis in non-human primate and mouse models of pneumonic plague.

scientific article

Development of Mast Cell and Eosinophil Hyperplasia and HLH/MAS-Like Disease in NSG-SGM3 Mice Receiving Human CD34+ Hematopoietic Stem Cells or Patient-Derived Leukemia Xenografts

scientific article published on 19 November 2020

Dietary modulation of the microbiome affects autoinflammatory disease

scientific article

Differential host response, rather than early viral replication efficiency, correlates with pathogenicity caused by influenza viruses

scientific article

Drak2 is not required for tumor surveillance and suppression

scientific article

Drug transporters on arachnoid barrier cells contribute to the blood-cerebrospinal fluid barrier.

scientific article published on 8 January 2013

Dynamics of Sendai virus spread, clearance, and immunotherapeutic efficacy after hematopoietic cell transplant imaged non-invasively in mice

scientific article published in November 2017

Early toxicology signal generation in the mouse.

scientific article published on 19 March 2010

Enhanced susceptibility of Ago1/3 double-null mice to influenza A virus infection.

scientific article published on 8 February 2012

Exogenous remodeling of lung resident macrophages protects against infectious consequences of bone marrow-suppressive chemotherapy

scientific article published on 26 September 2016

Exploring the elephant: histopathology in high-throughput phenotyping of mutant mice

scientific article published on 25 October 2011

Expression of variants of the major surface glycoprotein of Pneumocystis carinii

scientific article

Extracellular Signal-Regulated Kinase Signaling in CD4-Expressing Cells Inhibits Osteochondromas

scientific article

Exuberant fibroblast activity compromises lung function via ADAMTS4

scientific article published on 28 October 2020

GREMLIN 2 Mutations and Dental Anomalies.

scientific article

GSDMD is critical for autoinflammatory pathology in a mouse model of Familial Mediterranean Fever.

scientific article

Galactosaminogalactan activates the inflammasome to provide host protection

scientific article published on 02 December 2020

Genetic characterization and pathogenic potential of H10 avian influenza viruses isolated from live poultry markets in Bangladesh

scientific article published in Scientific Reports

Genetic deletion of Mst1 alters T cell function and protects against autoimmunity

scientific article

H1N1 influenza viruses varying widely in hemagglutinin stability transmit efficiently from swine to swine and to ferrets

scientific article

HIF1alpha-dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells

scientific article

Histopathology is required to identify and characterize myopathies in high-throughput phenotype screening of genetically engineered mice

scientific article published on 16 July 2021

Homeostasis and transitional activation of regulatory T cells require c-Myc

scientific article published on 01 January 2020

Human H7N9 and H5N1 influenza viruses differ in induction of cytokines and tissue tropism.

scientific article

IL-10 engages macrophages to shift Th17 cytokine dependency and pathogenicity during T-cell-mediated colitis

scientific article

IL-18 production downstream of the Nlrp3 inflammasome confers protection against colorectal tumor formation

scientific article

IL-1β and Caspase-1 Drive Autoinflammatory Disease Independently of IL-1α or Caspase-8 in a Mouse Model of Familial Mediterranean Fever

scientific article

Immune inhibitory molecules LAG-3 and PD-1 synergistically regulate T-cell function to promote tumoral immune escape

scientific article

Impaired wound healing predisposes obese mice to severe influenza virus infection

scientific article

Improved glycemic control in mice lacking Sglt1 and Sglt2.

scientific article published on 13 November 2012

Incomplete inhibition of sphingosine 1-phosphate lyase modulates immune system function yet prevents early lethality and non-lymphoid lesions

scientific article

Innate immune priming in the absence of TAK1 drives RIPK1 kinase activity-independent pyroptosis, apoptosis, necroptosis, and inflammatory disease

scientific article published on 01 March 2020

Interferon inducible GBPs restrict Burkholderia thailandensis motility induced cell-cell fusion

scientific article published on 09 March 2020

Keratinocyte migration in the developing eyelid requires LIMK2

scientific article

Keratinocytes contribute intrinsically to psoriasis upon loss of Tnip1 function.

scientific article published on 26 September 2016

Lipid signalling enforces functional specialization of T<sub>reg</sub> cells in tumours

scientific article published on 24 February 2021

Lipid-lowering effects of anti-angiopoietin-like 4 antibody recapitulate the lipid phenotype found in angiopoietin-like 4 knockout mice

scientific article (publication date: 10 July 2007)

MYCN amplification and ATRX mutations are incompatible in neuroblastoma

scientific article published on 14 February 2020

Metabolic heterogeneity underlies reciprocal fates of TH17 cell stemness and plasticity.

scientific article published on 19 December 2018

Mice lacking alpha/beta subunits of GlcNAc-1-phosphotransferase exhibit growth retardation, retinal degeneration, and secretory cell lesions

scientific article

Mouse model of sublethal and lethal intraperitoneal glanders (Burkholderia mallei)

scientific article published on 01 November 2000

NLRP6 negatively regulates innate immunity and host defence against bacterial pathogens

scientific journal article

Negative regulation of the NLRP3 inflammasome by A20 protects against arthritis

scientific article

Nonstructural protein 1 (NS1)-mediated inhibition of c-Abl results in acute lung injury and priming for bacterial co-infections: insights into 1918 H1N1 pandemic?

scientific article

Ocular albinism and hypopigmentation defects in Slc24a5-/- mice.

scientific article published in March 2008

PATHBIO: an international training program for precision mouse phenotyping

scientific article published on 22 February 2020

Pathology of congenital generalized lipodystrophy in Agpat2-/- mice

scientific article published on 04 November 2010

Patrolling monocytes promote the pathogenesis of early lupus-like glomerulonephritis

scientific article published on 29 April 2019

Predicting human disease mutations and identifying drug targets from mouse gene knockout phenotyping campaigns.

scientific article published on 7 May 2019

Profound obesity secondary to hyperphagia in mice lacking kinase suppressor of ras 2

scientific article published on 02 December 2010

Progressive Degenerative Myopathy and Myosteatosis in ASNSD1-Deficient Mice

scientific article published on 08 July 2020

Publisher Correction: Exuberant fibroblast activity compromises lung function via ADAMTS4

scientific article published on 18 November 2020

Publisher Correction: Galactosaminogalactan activates the inflammasome to provide host protection

scientific article published on 21 December 2020

Pyrin Inflammasome Regulates Tight Junction Integrity to Restrict Colitis and Tumorigenesis

scientific article published in December 2017

RIP1-driven autoinflammation targets IL-1α independently of inflammasomes and RIP3.

scientific article published on 26 May 2013

Rapalog resistance is associated with mesenchymal-type changes in Tsc2-null cells

scientific article published on 28 February 2019

Rapid postmortem invasion of cecal mucosa of macaques by nonpathogenic Entamoeba chattoni.

scientific article published in December 1996

Reactive oxygen species regulate caspase-11 expression and activation of the non-canonical NLRP3 inflammasome during enteric pathogen infection

scientific article

Receptor interacting protein kinase 2-mediated mitophagy regulates inflammasome activation during virus infection

scientific article published on 24 March 2013

Recipient myeloid-derived immunomodulatory cells induce PD-1 ligand-dependent donor CD4+Foxp3+ regulatory T cell proliferation and donor-recipient immune tolerance after murine nonmyeloablative bone marrow transplantation

scientific article published on 4 November 2013

Regulators of the proteasome pathway, Uch37 and Rpn13, play distinct roles in mouse development

scientific journal article

Relationships among dissemination of primary parainfluenza virus infection in the respiratory tract, mucosal and peripheral immune responses, and protection from reinfection: a noninvasive bioluminescence-imaging study

scientific article

Replication and pathogenic potential of influenza A virus subtypes H3, H7, and H15 from free-range ducks in Bangladesh in mammals.

scientific article

Requirement for antiapoptotic MCL-1 during early erythropoiesis

Role of inflammasomes in host defense against Citrobacter rodentium infection

scientific article

SIL1, the endoplasmic-reticulum-localized BiP co-chaperone, plays a crucial role in maintaining skeletal muscle proteostasis and physiology.

scientific article published on 9 April 2018

Salmonella exploits NLRP12-dependent innate immune signaling to suppress host defenses during infection

scientific article published on 17 December 2013

Signaling via the kinase p38α programs dendritic cells to drive TH17 differentiation and autoimmune inflammation

scientific article published on 8 January 2012

Situs inversus in Dpcd/Poll-/-, Nme7-/- , and Pkd1l1-/- mice

scientific journal article

Spectrum of Posttransplant Lymphoproliferations in NSG Mice and Their Association With EBV Infection After Engraftment of Pediatric Solid Tumors

scientific article published on 23 March 2020

Spontaneous acute tumor lysis syndrome as a cause of early deaths in short-term carcinogenicity studies using p53 +/- mice

scientific article published on 30 April 2010

Spontaneous acute tumor lysis syndrome in a DBA/1J mouse: a case report and review.

scientific article published on September 2003

Stability and function of regulatory T cells is maintained by a neuropilin-1-semaphorin-4a axis.

scientific article

Targeted disruption of leucine-rich repeat kinase 1 but not leucine-rich repeat kinase 2 in mice causes severe osteopetrosis

scientific journal article

The Agents of Biological Warfare ⬇️

scientific article published on August 6, 1997

The Hemagglutinin Stem-Binding Monoclonal Antibody VIS410 Controls Influenza Virus-Induced Acute Respiratory Distress Syndrome

scientific article published on 19 January 2016

The NLRP12 Sensor Negatively Regulates Autoinflammatory Disease by Modulating Interleukin-4 Production in T Cells

scientific article

The NLRP3 inflammasome protects against loss of epithelial integrity and mortality during experimental colitis

scientific article

The NOD-like receptor NLRP12 attenuates colon inflammation and tumorigenesis.

scientific article

The severity of hereditary porphyria is modulated by the porphyrin exporter and Lan antigen ABCB6.

scientific article published on 10 August 2016

The weaned pig as a model for Doxorubicin-induced mucositis

scientific article published on 21 October 2014

Toll or interleukin-1 receptor (TIR) domain-containing adaptor inducing interferon-β (TRIF)-mediated caspase-11 protease production integrates Toll-like receptor 4 (TLR4) protein- and Nlrp3 inflammasome-mediated host defense against enteropathogens

scientific article

Toxicity of the staphylococcal enterotoxin B mutants with histidine-to-tyrosine substitutions.

scientific article published in May 2003

Transforming growth factor beta-activated kinase 1 (TAK1)-dependent checkpoint in the survival of dendritic cells promotes immune homeostasis and function.

scientific article published on 23 January 2012

Tyrosine Kinase SYK Licenses MyD88 Adaptor Protein to Instigate IL-1α-Mediated Inflammatory Disease

scientific article

ZBP1-dependent inflammatory cell death, PANoptosis, and cytokine storm disrupt IFN therapeutic efficacy during coronavirus infection

scientific article published on 19 May 2022

mTOR coordinates transcriptional programs and mitochondrial metabolism of activated Treg subsets to protect tissue homeostasis.

scientific article

mTORC1 couples immune signals and metabolic programming to establish T(reg)-cell function

scientific article published on 30 June 2013

List of works by Peter Vogel

A Perfect Storm: Increased Colonization and Failure of Vaccination Leads to Severe Secondary Bacterial Infection in Influenza Virus-Infected Obese Mice

A Single Point Mutation (Y89F) within the Non-Structural Protein 1 of Influenza A Viruses Limits Epithelial Cell Tropism and Virulence in Mice

A live-attenuated pneumococcal vaccine elicits CD4+ T-cell dependent class switching and provides serotype independent protection against acute otitis media

A mouse model of hereditary folate malabsorption: deletion of the PCFT gene leads to systemic folate deficiency.

A novel cytotoxic sequence contributes to influenza A viral protein PB1-F2 pathogenicity and predisposition to secondary bacterial infection

ASK Family Kinases Are Required for Optimal NLRP3 Inflammasome Priming

Abcb11 deficiency induces cholestasis coupled to impaired β-fatty acid oxidation in mice

Acute Lung Injury Results from Innate Sensing of Viruses by an ER Stress Pathway

Aerosolized specific antibody protects mice from lung injury associated with aerosolized ricin exposure

Allergic inflammation alters the lung microbiome and hinders synergistic co-infection with H1N1 influenza virus and Streptococcus pneumoniae in C57BL/6 mice

An NLRP3 inflammasome-triggered Th2-biased adaptive immune response promotes leishmaniasis

Antibody-secreting cells in respiratory tract tissues in the absence of eosinophils as supportive partners

Astrovirus infects actively secreting goblet cells and alters the gut mucus barrier

Autophagy enforces functional integrity of regulatory T cells by coupling environmental cues and metabolic homeostasis

CRISPR screens unveil signal hubs for nutrient licensing of T cell immunity

Cardiomyopathy associated with angiomatous pheochromocytoma in a rhesus macaque (Macaca mulatta).

Characterization of a multicopy family of genes encoding a surface-expressed serine endoprotease in rat Pneumocystis carinii

Comparative neurovirulence and tissue tropism of wild-type and attenuated strains of Venezuelan equine encephalitis virus administered by aerosol in C3H/HeN and BALB/c mice.

Comparative pathology of murine mucolipidosis types II and IIIC

Competitive Fitness of Influenza B Viruses Possessing E119A and H274Y Neuraminidase Inhibitor Resistance-Associated Substitutions in Ferrets

Compromised respiratory function in lethal influenza infection is characterized by the depletion of type I alveolar epithelial cells beyond threshold levels

Concerted activation of the AIM2 and NLRP3 inflammasomes orchestrates host protection against Aspergillus infection

Congenital hydrocephalus in genetically engineered mice

Critical Role for the DNA Sensor AIM2 in Stem Cell Proliferation and Cancer

Critical roles of mTORC1 signaling and metabolic reprogramming for M-CSF-mediated myelopoiesis.

Cryptogenic organizing pneumonia in Tomm5(-/-) mice

Cutting edge: STING mediates protection against colorectal tumorigenesis by governing the magnitude of intestinal inflammation

DAI Senses Influenza A Virus Genomic RNA and Activates RIPK3-Dependent Cell Death

DOCK2 confers immunity and intestinal colonization resistance to Citrobacter rodentium infection

Data from CAR T-cell Design-dependent Remodeling of the Brain Tumor Immune Microenvironment Modulates Tumor-associated Macrophages and Anti-glioma Activity

Determination of the virulence of the pigmentation-deficient and pigmentation-/plasminogen activator-deficient strains of Yersinia pestis in non-human primate and mouse models of pneumonic plague.

Development of Mast Cell and Eosinophil Hyperplasia and HLH/MAS-Like Disease in NSG-SGM3 Mice Receiving Human CD34+ Hematopoietic Stem Cells or Patient-Derived Leukemia Xenografts

Dietary modulation of the microbiome affects autoinflammatory disease

Differential host response, rather than early viral replication efficiency, correlates with pathogenicity caused by influenza viruses

Drak2 is not required for tumor surveillance and suppression

Drug transporters on arachnoid barrier cells contribute to the blood-cerebrospinal fluid barrier.

Dynamics of Sendai virus spread, clearance, and immunotherapeutic efficacy after hematopoietic cell transplant imaged non-invasively in mice

Early toxicology signal generation in the mouse.

Enhanced susceptibility of Ago1/3 double-null mice to influenza A virus infection.

Exogenous remodeling of lung resident macrophages protects against infectious consequences of bone marrow-suppressive chemotherapy

Exploring the elephant: histopathology in high-throughput phenotyping of mutant mice

Expression of variants of the major surface glycoprotein of Pneumocystis carinii

Extracellular Signal-Regulated Kinase Signaling in CD4-Expressing Cells Inhibits Osteochondromas

Exuberant fibroblast activity compromises lung function via ADAMTS4

GREMLIN 2 Mutations and Dental Anomalies.

GSDMD is critical for autoinflammatory pathology in a mouse model of Familial Mediterranean Fever.

Galactosaminogalactan activates the inflammasome to provide host protection

Genetic characterization and pathogenic potential of H10 avian influenza viruses isolated from live poultry markets in Bangladesh

Genetic deletion of Mst1 alters T cell function and protects against autoimmunity

H1N1 influenza viruses varying widely in hemagglutinin stability transmit efficiently from swine to swine and to ferrets

HIF1alpha-dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells

Histopathology is required to identify and characterize myopathies in high-throughput phenotype screening of genetically engineered mice

Homeostasis and transitional activation of regulatory T cells require c-Myc

Human H7N9 and H5N1 influenza viruses differ in induction of cytokines and tissue tropism.

IL-10 engages macrophages to shift Th17 cytokine dependency and pathogenicity during T-cell-mediated colitis

IL-18 production downstream of the Nlrp3 inflammasome confers protection against colorectal tumor formation

IL-1β and Caspase-1 Drive Autoinflammatory Disease Independently of IL-1α or Caspase-8 in a Mouse Model of Familial Mediterranean Fever

Immune inhibitory molecules LAG-3 and PD-1 synergistically regulate T-cell function to promote tumoral immune escape

Impaired wound healing predisposes obese mice to severe influenza virus infection

Improved glycemic control in mice lacking Sglt1 and Sglt2.

Incomplete inhibition of sphingosine 1-phosphate lyase modulates immune system function yet prevents early lethality and non-lymphoid lesions

Innate immune priming in the absence of TAK1 drives RIPK1 kinase activity-independent pyroptosis, apoptosis, necroptosis, and inflammatory disease

Interferon inducible GBPs restrict Burkholderia thailandensis motility induced cell-cell fusion

Keratinocyte migration in the developing eyelid requires LIMK2

Keratinocytes contribute intrinsically to psoriasis upon loss of Tnip1 function.

Lipid signalling enforces functional specialization of T<sub>reg</sub> cells in tumours

Lipid-lowering effects of anti-angiopoietin-like 4 antibody recapitulate the lipid phenotype found in angiopoietin-like 4 knockout mice

MYCN amplification and ATRX mutations are incompatible in neuroblastoma

Metabolic heterogeneity underlies reciprocal fates of TH17 cell stemness and plasticity.

Mice lacking alpha/beta subunits of GlcNAc-1-phosphotransferase exhibit growth retardation, retinal degeneration, and secretory cell lesions

Mouse model of sublethal and lethal intraperitoneal glanders (Burkholderia mallei)

NLRP6 negatively regulates innate immunity and host defence against bacterial pathogens

Negative regulation of the NLRP3 inflammasome by A20 protects against arthritis

Nonstructural protein 1 (NS1)-mediated inhibition of c-Abl results in acute lung injury and priming for bacterial co-infections: insights into 1918 H1N1 pandemic?

Ocular albinism and hypopigmentation defects in Slc24a5-/- mice.

PATHBIO: an international training program for precision mouse phenotyping

Pathology of congenital generalized lipodystrophy in Agpat2-/- mice

Patrolling monocytes promote the pathogenesis of early lupus-like glomerulonephritis

Predicting human disease mutations and identifying drug targets from mouse gene knockout phenotyping campaigns.