List of works - Cyril Rauch

A quantitative systems pharmacology approach, incorporating a novel liver model, for predicting pharmacokinetic drug-drug interactions.

scientific article published on 14 September 2017

Acid-mediated Lipinski's second rule: application to drug design and targeting in cancer

scientific article published on April 2014

C2C12 skeletal muscle cells exposure to phosphatidylcholine triggers IGF-1 like-responses.

scientific article published in January 2005

Can long range mechanical interaction between drugs and membrane proteins define the notion of molecular promiscuity? Application to P-glycoprotein-mediated multidrug resistance (MDR).

scientific article published on 10 July 2013

Cariporide and other new and powerful NHE1 inhibitors as potentially selective anticancer drugs--an integral molecular/biochemical/metabolic/clinical approach after one hundred years of cancer research

scientific article

Cellular acidification as a new approach to cancer treatment and to the understanding and therapeutics of neurodegenerative diseases.

scientific article published on 10 February 2017

Cyclosporin-A inhibits stretch-induced changes in myosin heavy chain expression in C2C12 skeletal muscle cells.

scientific article

Erratum: Glycolysis, tumor metabolism, cancer growth and dissemination. A new pH-based etiopathogenic perspective and therapeutic approach to an old cancer question.

scientific article published on 18 December 2014

Glycolysis, tumor metabolism, cancer growth and dissemination. A new pH-based etiopathogenic perspective and therapeutic approach to an old cancer question

scientific article

Impact of maternal dietary fat supplementation during gestation upon skeletal muscle in neonatal pigs

scientific article

Inward relocation of exogenous phosphatidylserine triggered by IGF-1 in non-apoptotic C2C12 cells is concentration dependent.

scientific article published on November 2005

Mechanism of mucosal permeability enhancement of CriticalSorb® (Solutol® HS15) investigated in vitro in cell cultures.

scientific article published on 5 September 2014

Microenvironment acidity as a major determinant of tumor chemoresistance: Proton pump inhibitors (PPIs) as a novel therapeutic approach.

scientific article published on 22 August 2015

Non-genomic steroid effects: merging membrane fluidity and receptor-mediated responses

scientific article published on 12 September 2007

Nongenomic effects of cisplatin: acute inhibition of mechanosensitive transporters and channels without actin remodeling.

scientific article

On some aspects of the thermodynamic of membrane recycling mediated by fluid phase endocytosis: evaluation of published data and perspectives.

scientific article

On the relationship between drug's size, cell membrane mechanical properties and high levels of multi drug resistance: a comparison to published data

scientific article

Physical and biological characteristics of multi drug resistance (MDR): An integral approach considering pH and drug resistance in cancer

scientific article published on 8 January 2017

Physics of nail conditions: why do ingrown nails always happen in the big toes?

scientific article published on 16 October 2014

Proton dynamics in cancer

scientific article published on 15 June 2010

Proton pump inhibitors for the treatment of cancer in companion animals.

scientific article

Resistance to cancer chemotherapy: failure in drug response from ADME to P-gp.

scientific article published on 15 July 2015

Static stretch promotes MEF2A nuclear translocation and expression of neonatal myosin heavy chain in C2C12 myocytes in a calcineurin- and p38-dependent manner.

scientific article

Stretch-induced activation of ERK in myocytes is p38 and calcineurin-dependent

scientific article published on 01 December 2008

Teaching new dogs old tricks: membrane biophysical properties in drug delivery and resistance.

scientific article published on September 2011

The "multi" of drug resistance explained by oscillating drug transporters, drug-membrane physical interactions and spatial dimensionality.

scientific article published in September 2011

The bio-physics of condensation of divalent cations into the bacterial wall has implications for growth of Gram-positive bacteria

scientific article published on 7 December 2016

Theoretical evaluation of wall teichoic acids in the cavitation-mediated pores formation in Gram-positive bacteria subjected to an electric field

scientific article published on 11 December 2014

Toward a mechanical control of drug delivery. On the relationship between Lipinski's 2nd rule and cytosolic pH changes in doxorubicin resistance levels in cancer cells: a comparison to published data

scientific article

List of works by Cyril Rauch

A quantitative systems pharmacology approach, incorporating a novel liver model, for predicting pharmacokinetic drug-drug interactions.

Acid-mediated Lipinski's second rule: application to drug design and targeting in cancer

C2C12 skeletal muscle cells exposure to phosphatidylcholine triggers IGF-1 like-responses.

Can long range mechanical interaction between drugs and membrane proteins define the notion of molecular promiscuity? Application to P-glycoprotein-mediated multidrug resistance (MDR).

Cariporide and other new and powerful NHE1 inhibitors as potentially selective anticancer drugs--an integral molecular/biochemical/metabolic/clinical approach after one hundred years of cancer research

Cellular acidification as a new approach to cancer treatment and to the understanding and therapeutics of neurodegenerative diseases.

Cyclosporin-A inhibits stretch-induced changes in myosin heavy chain expression in C2C12 skeletal muscle cells.

Erratum: Glycolysis, tumor metabolism, cancer growth and dissemination. A new pH-based etiopathogenic perspective and therapeutic approach to an old cancer question.

Glycolysis, tumor metabolism, cancer growth and dissemination. A new pH-based etiopathogenic perspective and therapeutic approach to an old cancer question

Impact of maternal dietary fat supplementation during gestation upon skeletal muscle in neonatal pigs

Inward relocation of exogenous phosphatidylserine triggered by IGF-1 in non-apoptotic C2C12 cells is concentration dependent.

Mechanism of mucosal permeability enhancement of CriticalSorb® (Solutol® HS15) investigated in vitro in cell cultures.

Microenvironment acidity as a major determinant of tumor chemoresistance: Proton pump inhibitors (PPIs) as a novel therapeutic approach.

Non-genomic steroid effects: merging membrane fluidity and receptor-mediated responses

Nongenomic effects of cisplatin: acute inhibition of mechanosensitive transporters and channels without actin remodeling.

On some aspects of the thermodynamic of membrane recycling mediated by fluid phase endocytosis: evaluation of published data and perspectives.

On the relationship between drug's size, cell membrane mechanical properties and high levels of multi drug resistance: a comparison to published data

Physical and biological characteristics of multi drug resistance (MDR): An integral approach considering pH and drug resistance in cancer

Physics of nail conditions: why do ingrown nails always happen in the big toes?

Proton dynamics in cancer

Proton pump inhibitors for the treatment of cancer in companion animals.

Resistance to cancer chemotherapy: failure in drug response from ADME to P-gp.

Static stretch promotes MEF2A nuclear translocation and expression of neonatal myosin heavy chain in C2C12 myocytes in a calcineurin- and p38-dependent manner.

Stretch-induced activation of ERK in myocytes is p38 and calcineurin-dependent

Teaching new dogs old tricks: membrane biophysical properties in drug delivery and resistance.

The "multi" of drug resistance explained by oscillating drug transporters, drug-membrane physical interactions and spatial dimensionality.

The bio-physics of condensation of divalent cations into the bacterial wall has implications for growth of Gram-positive bacteria

Theoretical evaluation of wall teichoic acids in the cavitation-mediated pores formation in Gram-positive bacteria subjected to an electric field

Toward a mechanical control of drug delivery. On the relationship between Lipinski's 2nd rule and cytosolic pH changes in doxorubicin resistance levels in cancer cells: a comparison to published data