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List of works by Hongtao Zhao

Current kinase inhibitors cover a tiny fraction of fragment space.

scientific article published on 10 April 2015

Discovery of BRD4 bromodomain inhibitors by fragment-based high-throughput docking

scientific article

Discovery of ZAP70 inhibitors by high-throughput docking into a conformation of its kinase domain generated by molecular dynamics.

scientific article published on 11 August 2013

Discovery of a Novel Chemotype of Tyrosine Kinase Inhibitors by Fragment-Based Docking and Molecular Dynamics

scientific article

Discovery of dual ZAP70 and Syk kinases inhibitors by docking into a rare C-helix-out conformation of Syk.

scientific article published on 10 February 2014

Discovery of tyrosine kinase inhibitors by docking into an inactive kinase conformation generated by molecular dynamics.

scientific article

Electrochemical biosensors for DNA analysis

scientific article

Enriching screening libraries with bioactive fragment space.

scientific article

Hydrogen bonding penalty upon ligand binding

scientific article

Identification and regulation of the catalytic promiscuity of (-)-γ-lactamase from Microbacterium hydrocarbonoxydans

scientific article published on 17 March 2015

Molecular dynamics in drug design.

scientific article

Multilayer membranes for glucose biosensing via layer-by-layer assembly of multiwall carbon nanotubes and glucose oxidase.

scientific article published on 20 December 2005

PARP1 ADP-ribosylates lysine residues of the core histone tails

scientific article

Structural Analysis of the Binding of Type I, I1/2, and II Inhibitors to Eph Tyrosine Kinases

scientific article

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