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List of works by Celia Greenwood

A Bayesian hierarchical model for improving measurement of 5mC and 5hmC levels: Toward revealing associations between phenotypes and methylation states

scientific article published in 2022

A flexible copula-based approach for the analysis of secondary phenotypes in ascertained samples

scientific article published on 23 December 2019

A hidden markov model for identifying differentially methylated sites in bisulfite sequencing data

scientific article published on 09 October 2018

A method for analyzing multiple continuous phenotypes in rare variant association studies allowing for flexible correlations in variant effects ⬇️

scientific article published on 10 February 2016

A preclinical trial and molecularly-annotated patient cohort identify predictive biomarkers in homologous recombination deficient pancreatic cancer

scientific article published on 14 August 2020

A rare variant association test in family-based designs and non-normal quantitative traits.

scientific article

A region-based gene association study combined with a leave-one-out sensitivity analysis identifies SMG1 as a pancreatic cancer susceptibility gene

scientific article published on 30 August 2019

A smoothed EM-algorithm for DNA methylation profiles from sequencing-based methods in cell lines or for a single cell type

scientific article published on 23 October 2017

A tree-based model for allele-sharing-based linkage analysis in human complex diseases.

scientific article published in February 2006

Adjusted sequence kernel association test for rare variants controlling for cryptic and family relatedness.

scientific article published on 25 March 2013

An evaluation of methods correcting for cell-type heterogeneity in DNA methylation studies

scientific article published on 3 May 2016

Analysis of genomic abnormalities in tumors: a review of available methods for Illumina two-color SNP genotyping and evaluation of performance.

scientific article published on 25 April 2013

Assessing transmission ratio distortion in extended families: a comparison of analysis methods

scientific article

Association between Variants in Atopy-Related Immunologic Candidate Genes and Pancreatic Cancer Risk

scientific article published on 6 May 2015

Association between the interleukin-1 family gene cluster and psoriatic arthritis

scientific article published on 01 July 2006

Association of toll-like receptor 4 variants and ankylosing spondylitis: a case-control study

article

At the interface

scientific article published on 10 January 2020

Breast and ovarian cancer: Y do we forget about dad?

scientific article published on 01 December 2010

Breast and ovarian cancer: the forgotten paternal contribution.

scientific article published on 19 April 2011

Carcinoembryonic Antigen Cell Adhesion Molecule 1 long isoform modulates malignancy of poorly differentiated colon cancer cells.

scientific article published on 9 February 2015

Characterization of a novel founderMSH6mutation causing Lynch syndrome in the French Canadian population

article

Chromosome 3 anomalies investigated by genome wide SNP analysis of benign, low malignant potential and low grade ovarian serous tumours

scientific article

Chromosome-breakage genomic instability and chromothripsis in breast cancer

scientific article

Combined polygenic risk scores of different psychiatric traits predict general and specific psychopathology in childhood

scientific article published in 2021

Constitutive differences in gene expression profiles parallel genetic patterns of susceptibility to tuberculosis in mice.

scientific article published on June 2006

Constrained instruments and their application to Mendelian randomization with pleiotropy

scientific article published on 12 January 2019

Corrections to the parameterization of constraints on allele sharing in sibling pairs alter covariate-parameter estimates but not sharing-probability estimates or power of tests for linkage.

scientific article published on January 2005

Corrigendum: Exploring the potential benefits of stratified false discovery rates for region-based testing of association with rare genetic variation.

scientific article

Data integration in genetics and genomics: methods and challenges

scientific article (publication date: 12 January 2009)

Development of a polygenic risk score to improve screening for fracture risk: A genetic risk prediction study

scientific article published on 02 July 2020

Differential gene profiling in acute lung injury identifies injury-specific gene expression.

scientific article published on March 2008

Effect of genome-wide genotyping and reference panels on rare variants imputation

scientific article published on 24 July 2012

Efficient p-value estimation in massively parallel testing problems.

scientific article published on 27 February 2008

Elevated rates of schizophrenia in a familial sample with mental illness and intellectual disability

scientific article

EphA2 signaling is impacted by carcinoembryonic antigen cell adhesion molecule 1-L expression in colorectal cancer liver metastasis in a cell context-dependent manner

scientific article published in November 2017

Erratum: Whole-genome sequence-based analysis of thyroid function

scientific article published on 20 May 2015

Estimating genome-wide significance for whole-genome sequencing studies

scientific article published on 14 February 2014

Estimating the effects of copy-number variants on intelligence using hierarchical Bayesian models

scientific article published on 11 August 2020

Evaluation of genetic and environmental effects using GEE and APM methods.

scientific article published in January 1995

Evidence of linkage to chromosome 1 for early age of onset of rheumatoid arthritis and HLA marker DRB1 genotype in NARAC data

scientific article

Exome-wide rare variant analyses of two bone mineral density phenotypes: the challenges of analyzing rare genetic variation

scientific article published on 9 January 2018

Exploring the potential benefits of stratified false discovery rates for region-based testing of association with rare genetic variation

scientific article published on 29 January 2014

Filaggrin gene mutation associations with peanut allergy persist despite variations in peanut allergy diagnostic criteria or asthma status

scientific article published on 16 May 2013

Functional normalization of 450k methylation array data improves replication in large cancer studies.

scientific article

Gene Coexpression Analyses Differentiate Networks Associated with Diverse Cancers Harboring TP53 Missense or Null Mutations

scientific article published on 03 August 2016

Gene genealogies for genetic association mapping, with application to Crohn's disease.

scientific article published on 2 December 2013

Gene networks show associations with seed region connectivity.

scientific article

Genetic Landscapes of Relapsed and Refractory Diffuse Large B-Cell Lymphomas.

scientific article

Genetic architecture: the shape of the genetic contribution to human traits and disease

scientific article published on 11 December 2017

Genome-wide analysis of gene dosage in 24,092 individuals estimates that 10,000 genes modulate cognitive ability

scientific article published on 07 January 2021

Germ-line DNA copy number variation frequencies in a large North American population

scientific article published on 19 July 2007

Haplotype inference using a Bayesian Hidden Markov model.

scientific article published in December 2007

High resolution mapping in the major histocompatibility complex region identifies multiple independent novel loci for psoriatic arthritis ⬇️

scientific article published on January 17, 2011

How old is this mutation? - a study of three Ashkenazi Jewish founder mutations.

scientific article

Identification of 153 new loci associated with heel bone mineral density and functional involvement of GPC6 in osteoporosis.

scientific article published on 4 September 2017

Identification of a Radiosensitivity Molecular Signature Induced by Enzalutamide in Hormone-sensitive and Hormone-resistant Prostate Cancer Cells.

scientific article published on 20 June 2019

Identifying cis- and trans-acting single-nucleotide polymorphisms controlling lymphocyte gene expression in humans

scientific article

Inactivation of Interferon Regulatory Factor 1 Causes Susceptibility to Colitis-Associated Colorectal Cancer

scientific article published on 11 December 2019

Incorporation of covariates into genome scanning using sib-pair analysis in bipolar affective disorder ⬇️

scientific article published on January 1, 1997

Inheritance patterns of maternal alleles in imprinted regions of the mouse genome at different stages of development

scientific article published on 01 January 2002

Interleukin 1 polymorphisms in patients with ankylosing spondylitis in Korea

article

Jackknife bias reduction for polychotomous logistic regression.

scientific article published in March 1997

Joint analysis of multiple blood pressure phenotypes in GAW19 data by using a multivariate rare-variant association test.

scientific article

Lack of association of SLC22A4, SLC22A5, SLC9A3R1 and RUNX1 variants in psoriatic arthritis

scientific article published on 15 March 2005

Mapping cis-acting regulatory variation in recombinant congenic strains

article

Microarray meta-analysis identifies acute lung injury biomarkers in donor lungs that predict development of primary graft failure in recipients

scientific article

Model-Free Linkage Analysis of a Binary Trait.

scientific article published in January 2017

Model-free linkage analysis of a binary trait

scientific article published on 01 January 2012

Multiple regression methods show great potential for rare variant association tests.

scientific article

Novel approaches to discovery of biomarkers in rheumatoid arthritis: comment on the article by Oswald et al

scientific article published on 01 May 2015

Novel insights into systemic autoimmune rheumatic diseases using shared molecular signatures and an integrative analysis

scientific article published on 7 April 2017

Optimal selection of markers for validation or replication from genome-wide association studies

scientific article published on 01 July 2007

Outcome-Related Differences in Gene Expression Profiles of High-Grade Serous Ovarian Cancers Following Neoadjuvant Chemotherapy

scientific article published on 17 September 2019

Pathway analysis for genetic association studies: to do, or not to do? That is the question

scientific article published on 17 June 2014

Pedigree selection and tests of linkage in a Hutterite asthma pedigree.

scientific article published on January 2001

Phase 2 study of panobinostat with or without rituximab in relapsed diffuse large B-cell lymphoma

scientific article published on 10 May 2016

Polymorphisms in Toll-Like Receptor 4 Are Not Associated with Asthma or Atopy-related Phenotypes

scientific article published on 25 September 2002

Racial differences in survival of patients on dialysis.

scientific article

Rare susceptibility variants for bipolar disorder suggest a role for G protein-coupled receptors.

scientific article published on 21 November 2017

Re: Familial aggregation of clinical and neurocognitive features in sibling pairs with and without schizophrenia.

scientific article published on 17 November 2009

Resistance to different anthracycline chemotherapeutics elicits distinct and actionable primary metabolic dependencies in breast cancer

scientific article published in 2021

Response to: Correcting for cell-type effects in DNA methylation studies: reference-based method outperforms latent variable approaches in empirical studies.

scientific article

Salt, blood pressure, and cointervention

scientific article published on 01 December 1997

Significant proportion of breast and/or ovarian cancer families of French Canadian descent harbor 1 of 5BRCA1 andBRCA2 mutations

article

Simultaneous SNP selection and adjustment for population structure in high dimensional prediction models

scientific article published on 04 May 2020

Software Application Profile: RVPedigree: a suite of family-based rare variant association tests for normally and non-normally distributed quantitative traits.

scientific article

Somatic point mutations occurring early in development: a monozygotic twin study.

scientific article

Specific variants in the MLH1 gene region may drive DNA methylation, loss of protein expression, and MSI-H colorectal cancer

scientific article

Stability of the human sperm DNA methylome to folic acid fortification and short-term supplementation

scientific article published on 18 December 2016

Statistical issues in a metaregression analysis of randomized trials: impact on the dietary sodium intake and blood pressure relationship.

scientific article published in June 1999

Tests for differential gene expression using weights in oligonucleotide microarray experiments

scientific article published on 22 February 2006

The G84E mutation of HOXB13 is associated with increased risk for prostate cancer: results from the REDUCE trial

scientific article published on 7 February 2013

The Genetic and Molecular Analyses of RAD51C and RAD51D Identifies Rare Variants Implicated in Hereditary Ovarian Cancer from a Genetically Unique Population

scientific article published on 30 April 2022

The HNPCC associated MSH2*1906G-->C founder mutation probably originated between 1440 CE and 1715 CE in the Ashkenazi Jewish population.

scientific article

The causal effect of vitamin D binding protein (DBP) levels on calcemic and cardiometabolic diseases: a Mendelian randomization study

scientific article (publication date: October 2014)

The performance of a new local false discovery rate method on tests of association between coronary artery disease (CAD) and genome-wide genetic variants.

scientific article published on 20 September 2017

The protein phosphatase 2A regulatory subunit PR70 is a gonosomal melanoma tumor suppressor gene.

scientific article

The validity of circulating microRNAs in oncology: five years of challenges and contradictions.

scientific article published on 06 March 2014

Toward Precision Medicine: TBC1D4 Disruption Is Common Among the Inuit and Leads to Underdiagnosis of Type 2 Diabetes

scientific article published on 25 August 2016

Using gene genealogies to detect rare variants associated with complex traits.

scientific article published on 15 August 2014

Using the ratio of means as the effect size measure in combining results of microarray experiments.

scientific article

VEGF, FGF1, FGF2 and EGF gene polymorphisms and psoriatic arthritis

scientific article

Validation of linkage by sampling based on environmental exposures

scientific article published on 01 January 1999

Value of homogenous populations for gene identification in complex rheumatic diseases

scientific article published on 01 June 2005

Variants of the SFTPA1 and SFTPA2 genes and susceptibility to tuberculosis in Ethiopia.

scientific article published on 15 November 2005

Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits

scientific article published on 23 May 2017

Whole-genome sequence-based analysis of thyroid function.

scientific article

Whole-genome sequencing identifies EN1 as a determinant of bone density and fracture

scientific article

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