List of works - Andrew S Moore

A phase I/II trial of AT9283, a selective inhibitor of aurora kinase in children with relapsed or refractory acute leukemia: challenges to run early phase clinical trials for children with leukemia.

scientific article published on December 2016

A stable-isotope HPLC-MS/MS method to simplify storage of human whole blood samples for glutathione assay

scientific article published on 27 April 2012

ALK2 inhibitors display beneficial effects in preclinical models of mutant diffuse intrinsic pontine glioma

article

Activation of protein phosphatase 2A in FLT3+ acute myeloid leukemia cells enhances the cytotoxicity of FLT3 tyrosine kinase inhibitors.

scientific article published on 18 June 2016

Adaptation of the plasma inhibitory activity assay to detect Aurora, ABL and FLT3 kinase inhibition by AT9283 in pediatric leukemia.

scientific article published on 12 June 2011

Assessing the feasibility and validity of the Toronto Childhood Cancer Stage Guidelines: a population-based registry study

scientific article published on 01 February 2018

Aurora kinase inhibitors: novel small molecules with promising activity in acute myeloid and Philadelphia-positive leukemias.

scientific article published on 11 February 2010

BIRC5 (survivin) splice variant expression correlates with refractory disease and poor outcome in pediatric acute myeloid leukemia: a report from the Children's Oncology Group

scientific article published on 11 October 2013

Changes in cancer incidence and survival among Aboriginal and Torres Strait Islander children in Australia, 1997–2016

scientific article published in 2021

Development of a targeted sequencing approach to identify prognostic, predictive and diagnostic markers in paediatric solid tumours

scientific article published on 6 December 2017

Differential expression of MUC4, GPR110 and IL2RA defines two groups of CRLF2-rearranged acute lymphoblastic leukemia patients with distinct secondary lesions

scientific article published on 30 August 2017

EphA2 Is a Therapy Target in EphA2-Positive Leukemias but Is Not Essential for Normal Hematopoiesis or Leukemia

scientific article published on 17 June 2015

EphA3 as a target for antibody immunotherapy in acute lymphoblastic leukemia

scientific article published on 6 December 2016

Erratum to: Population pharmacokinetic modelling of doxorubicin and doxorubicinol in children with cancer: is there a relationship with cardiac troponin profiles?

scientific article

Functional diversity and cooperativity between subclonal populations of pediatric glioblastoma and diffuse intrinsic pontine glioma cells.

scientific article

HG-76SPATIAL AND TEMPORAL HOMOGENEITY OF DRIVER MUTATIONS IN DIFFUSE INTRINSIC PONTINE GLIOMA.

scientific article published on 30 May 2016

Hematopoietic stem cell transplantation for children with acute myeloid leukemia in second remission: A report from the Australasian Bone Marrow Transplant Recipient Registry and the Australian and New Zealand Children's Haematology Oncology Group

scientific article published on 20 May 2019

High prevalence of relapse in children with Philadelphia-like acute lymphoblastic leukemia despite risk-adapted treatment

scientific article published on 21 September 2017

Infant high grade gliomas comprise multiple subgroups characterized by novel targetable gene fusions and favorable outcomes

scientific article published on 01 April 2020

Integrated (epi)-Genomic Analyses Identify Subgroup-Specific Therapeutic Targets in CNS Rhabdoid Tumors

scientific article

Integrated Molecular Meta-Analysis of 1,000 Pediatric High-Grade and Diffuse Intrinsic Pontine Glioma

scientific article published on 26 September 2017

Intertumoral Heterogeneity within Medulloblastoma Subgroups

scientific article published on June 2017

Invasive fungal infections in children with acute lymphoblastic leukaemia: Results from four Australian centres, 2003-2013

scientific article published on 16 July 2019

Localised peripheral primitive neuroectodermal tumour (PNET) of the conjunctiva

scientific article published on 01 October 2009

Molecular Minimal Residual Disease Monitoring in Acute Myeloid Leukemia: Challenges and Future Directions.

scientific article published on 21 April 2018

New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs

scientific article

Novel therapies for children with acute myeloid leukaemia.

scientific article published on 08 April 2013

Optimization of Imidazo[4,5- b ]pyridine-Based Kinase Inhibitors: Identification of a Dual FLT3/Aurora Kinase Inhibitor as an Orally Bioavailable Preclinical Development Candidate for the Treatment of Acute Myeloid Leukemia

scientific article

Outcome of children relapsing after first allogeneic haematopoietic stem cell transplantation for acute myeloid leukaemia: a retrospective I-BFM analysis of 333 children

scientific article published on 03 February 2020

PTEN deletion drives acute myeloid leukemia resistance to MEK inhibitors

scientific article published on 08 October 2019

Pattern of Relapse and Treatment Response in WNT-Activated Medulloblastoma

scientific article published on 01 June 2020

Population pharmacokinetic modelling of doxorubicin and doxorubicinol in children with cancer: is there a relationship with cardiac troponin profiles?

scientific article published on 25 April 2017

Prognostic value of medulloblastoma extent of resection after accounting for molecular subgroup: a retrospective integrated clinical and molecular analysis

scientific article published on 11 March 2016

Quizartinib-resistant FLT3-ITD acute myeloid leukemia cells are sensitive to the FLT3-Aurora kinase inhibitor CCT241736

scientific article published on 01 April 2020

Second primary cancers in people who had cancer as children: an Australian Childhood Cancer Registry population-based study

scientific article published on 19 November 2019

Selective FLT3 inhibition of FLT3-ITD+ acute myeloid leukaemia resulting in secondary D835Y mutation: a model for emerging clinical resistance patterns

scientific article

Spatial and temporal homogeneity of driver mutations in diffuse intrinsic pontine glioma

scientific article published on 6 April 2016

Stage at diagnosis for children with blood cancers in Australia: Application of the Toronto Paediatric Cancer Stage Guidelines in a population-based national childhood cancer registry

scientific article published on 25 February 2019

Targetable kinase-activating lesions in Ph-like acute lymphoblastic leukemia

scientific article

Targeted Next-Generation Sequencing for Detecting MLL Gene Fusions in Leukemia.

scientific article published on 13 November 2017

Targeting survivin with YM155 (Sepantronium Bromide): a novel therapeutic strategy for paediatric acute myeloid leukaemia

scientific article published on 23 January 2015

Telomerase inhibition effectively targets mouse and human AML stem cells and delays relapse following chemotherapy

scientific article

The MLL recombinome of acute leukemias in 2017.

scientific article published on 13 July 2017

The incidence of childhood cancer in Australia, 1983-2015, and projections to 2035

scientific article published on 26 December 2019

The outcomes and treatment burden of childhood acute myeloid leukaemia in Australia, 1997-2008: A report from the Australian Paediatric Cancer Registry.

scientific article published on 8 April 2015

The ten-year evolutionary trajectory of a highly recurrent paediatric high grade neuroepithelial tumour with MN1:BEND2 fusion

scientific article published on 18 January 2018

Therapy-related acute myeloid leukemia following treatment for cancer in childhood: A population-based registry study

scientific article published on 05 September 2018

Vincristine pharmacodynamics and pharmacogenetics in children with cancer: a limited-sampling, population modelling approach

scientific article published on 09 June 2011

Vincristine sulfate liposomal injection for acute lymphoblastic leukemia

scientific article

Vincristine: Can its therapeutic index be enhanced?

scientific article published on December 2009

Whole genome, transcriptome and methylome profiling enhances actionable target discovery in high-risk pediatric cancer

scientific article published on 05 October 2020

List of works by Andrew S Moore

A phase I/II trial of AT9283, a selective inhibitor of aurora kinase in children with relapsed or refractory acute leukemia: challenges to run early phase clinical trials for children with leukemia.

A stable-isotope HPLC-MS/MS method to simplify storage of human whole blood samples for glutathione assay

ALK2 inhibitors display beneficial effects in preclinical models of mutant diffuse intrinsic pontine glioma

Activation of protein phosphatase 2A in FLT3+ acute myeloid leukemia cells enhances the cytotoxicity of FLT3 tyrosine kinase inhibitors.

Adaptation of the plasma inhibitory activity assay to detect Aurora, ABL and FLT3 kinase inhibition by AT9283 in pediatric leukemia.

Assessing the feasibility and validity of the Toronto Childhood Cancer Stage Guidelines: a population-based registry study

Aurora kinase inhibitors: novel small molecules with promising activity in acute myeloid and Philadelphia-positive leukemias.

BIRC5 (survivin) splice variant expression correlates with refractory disease and poor outcome in pediatric acute myeloid leukemia: a report from the Children's Oncology Group

Changes in cancer incidence and survival among Aboriginal and Torres Strait Islander children in Australia, 1997–2016

Development of a targeted sequencing approach to identify prognostic, predictive and diagnostic markers in paediatric solid tumours

Differential expression of MUC4, GPR110 and IL2RA defines two groups of CRLF2-rearranged acute lymphoblastic leukemia patients with distinct secondary lesions

EphA2 Is a Therapy Target in EphA2-Positive Leukemias but Is Not Essential for Normal Hematopoiesis or Leukemia

EphA3 as a target for antibody immunotherapy in acute lymphoblastic leukemia

Erratum to: Population pharmacokinetic modelling of doxorubicin and doxorubicinol in children with cancer: is there a relationship with cardiac troponin profiles?

Functional diversity and cooperativity between subclonal populations of pediatric glioblastoma and diffuse intrinsic pontine glioma cells.

HG-76SPATIAL AND TEMPORAL HOMOGENEITY OF DRIVER MUTATIONS IN DIFFUSE INTRINSIC PONTINE GLIOMA.

Hematopoietic stem cell transplantation for children with acute myeloid leukemia in second remission: A report from the Australasian Bone Marrow Transplant Recipient Registry and the Australian and New Zealand Children's Haematology Oncology Group

High prevalence of relapse in children with Philadelphia-like acute lymphoblastic leukemia despite risk-adapted treatment

Infant high grade gliomas comprise multiple subgroups characterized by novel targetable gene fusions and favorable outcomes

Integrated (epi)-Genomic Analyses Identify Subgroup-Specific Therapeutic Targets in CNS Rhabdoid Tumors

Integrated Molecular Meta-Analysis of 1,000 Pediatric High-Grade and Diffuse Intrinsic Pontine Glioma

Intertumoral Heterogeneity within Medulloblastoma Subgroups

Invasive fungal infections in children with acute lymphoblastic leukaemia: Results from four Australian centres, 2003-2013

Localised peripheral primitive neuroectodermal tumour (PNET) of the conjunctiva

Molecular Minimal Residual Disease Monitoring in Acute Myeloid Leukemia: Challenges and Future Directions.

New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs

Novel therapies for children with acute myeloid leukaemia.

Optimization of Imidazo[4,5- b ]pyridine-Based Kinase Inhibitors: Identification of a Dual FLT3/Aurora Kinase Inhibitor as an Orally Bioavailable Preclinical Development Candidate for the Treatment of Acute Myeloid Leukemia

Outcome of children relapsing after first allogeneic haematopoietic stem cell transplantation for acute myeloid leukaemia: a retrospective I-BFM analysis of 333 children

PTEN deletion drives acute myeloid leukemia resistance to MEK inhibitors

Pattern of Relapse and Treatment Response in WNT-Activated Medulloblastoma

Population pharmacokinetic modelling of doxorubicin and doxorubicinol in children with cancer: is there a relationship with cardiac troponin profiles?

Prognostic value of medulloblastoma extent of resection after accounting for molecular subgroup: a retrospective integrated clinical and molecular analysis

Quizartinib-resistant FLT3-ITD acute myeloid leukemia cells are sensitive to the FLT3-Aurora kinase inhibitor CCT241736

Second primary cancers in people who had cancer as children: an Australian Childhood Cancer Registry population-based study

Selective FLT3 inhibition of FLT3-ITD+ acute myeloid leukaemia resulting in secondary D835Y mutation: a model for emerging clinical resistance patterns

Spatial and temporal homogeneity of driver mutations in diffuse intrinsic pontine glioma

Stage at diagnosis for children with blood cancers in Australia: Application of the Toronto Paediatric Cancer Stage Guidelines in a population-based national childhood cancer registry

Targetable kinase-activating lesions in Ph-like acute lymphoblastic leukemia

Targeted Next-Generation Sequencing for Detecting MLL Gene Fusions in Leukemia.

Targeting survivin with YM155 (Sepantronium Bromide): a novel therapeutic strategy for paediatric acute myeloid leukaemia

Telomerase inhibition effectively targets mouse and human AML stem cells and delays relapse following chemotherapy

The MLL recombinome of acute leukemias in 2017.

The incidence of childhood cancer in Australia, 1983-2015, and projections to 2035

The outcomes and treatment burden of childhood acute myeloid leukaemia in Australia, 1997-2008: A report from the Australian Paediatric Cancer Registry.

The ten-year evolutionary trajectory of a highly recurrent paediatric high grade neuroepithelial tumour with MN1:BEND2 fusion

Therapy-related acute myeloid leukemia following treatment for cancer in childhood: A population-based registry study

Vincristine pharmacodynamics and pharmacogenetics in children with cancer: a limited-sampling, population modelling approach

Vincristine sulfate liposomal injection for acute lymphoblastic leukemia

Vincristine: Can its therapeutic index be enhanced?

Whole genome, transcriptome and methylome profiling enhances actionable target discovery in high-risk pediatric cancer