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List of works by Jingshan Ren

3'-Azido-3'-deoxythymidine drug resistance mutations in HIV-1 reverse transcriptase can induce long range conformational changes

scientific article

A RANKL mutant used as an inter-species vaccine for efficient immunotherapy of osteoporosis.

scientific article

A family of insertion mutations between codons 67 and 70 of human immunodeficiency virus type 1 reverse transcriptase confer multinucleoside analog resistance.

scientific article published on August 1999

A pipeline for the production of antibody fragments for structural studies using transient expression in HEK 293T cells

scientific article

A plate-based high-throughput assay for virus stability and vaccine formulation

scientific article published on 26 June 2012

A sensor-adaptor mechanism for enterovirus uncoating from structures of EV71

scientific article

Antiepileptic Drug Carbamazepine Binds to a Novel Pocket on the Wnt Receptor Frizzled-8

scientific article published on 25 February 2020

Binding of (5S)-penicilloic acid to penicillin binding protein 3

scientific article

Binding of the second generation non-nucleoside inhibitor S-1153 to HIV-1 reverse transcriptase involves extensive main chain hydrogen bonding

scientific article

Cachd1 interacts with Wnt receptors and regulates neuronal asymmetry in the zebrafish brain

scientific article published on 02 May 2024

Caffeine inhibits Notum activity by binding at the catalytic pocket

scientific article published on 08 October 2020

Cloning, expression, purification, and crystallisation of HIV-2 reverse transcriptase

article

Complexes of HIV-1 reverse transcriptase with inhibitors of the HEPT series reveal conformational changes relevant to the design of potent non-nucleoside inhibitors

scientific article

Continuous and Discontinuous Changes in the Unit Cell of HIV-1 Reverse Transcriptase Crystals on Dehydration

article

Correction to "Structure-Based in Silico Screening Identifies a Potent Ebolavirus Inhibitor from a Traditional Chinese Medicine Library"

scientific article published on 28 October 2019

Crystal Structures of Penicillin-Binding Protein 3 from Pseudomonas aeruginosa: Comparison of Native and Antibiotic-Bound Forms

scientific article

Crystal structure and mechanistic implications of 1-aminocyclopropane-1-carboxylic acid oxidase--the ethylene-forming enzyme.

scientific article

Crystal structure of CC3 (TIP30): implications for its role as a tumor suppressor

scientific article (publication date: 6 May 2005)

Crystal structure of SANOS, a bacterial nitric oxide synthase oxygenase protein from Staphylococcus aureus

scientific article

Crystal structure of human wildtype and S581L-mutant glycyl-tRNA synthetase, an enzyme underlying distal spinal muscular atrophy

scientific article

Crystal structure of human α-lactalbumin at 1·7 Å resolution

scientific article published on 01 September 1991

Crystal structure of nitrogen regulatory protein IIANtr from Neisseria meningitidis.

scientific article

Crystal structure of signal regulatory protein gamma (SIRPγ) in complex with an antibody Fab fragment

scientific article

Crystal structure of the Murray Valley encephalitis virus NS5 methyltransferase domain in complex with cap analogues

scientific article

Crystal structure of varicella zoster virus thymidine kinase

scientific article (publication date: 4 July 2003)

Crystal structures of HIV-1 reverse transcriptase in complex with carboxanilide derivatives

scientific article

Crystal structures of HIV-1 reverse transcriptases mutated at codons 100, 106 and 108 and mechanisms of resistance to non-nucleoside inhibitors.

scientific article published in February 2004

Crystal structures of Zidovudine- or Lamivudine-resistant human immunodeficiency virus type 1 reverse transcriptases containing mutations at codons 41, 184, and 215.

scientific article

Crystal structures of penicillin-binding protein 3 in complexes with azlocillin and cefoperazone in both acylated and deacylated forms

scientific article published on 23 January 2016

Crystallization and preliminary X-ray analysis of CrgA, a LysR-type transcriptional regulator from pathogenic Neisseria meningitidis MC58

scientific article published on 9 August 2008

Crystallization and preliminary X-ray analysis of mouse RANK and its complex with RANKL ⬇️

scientific article published on 22 May 2009

Crystallization and preliminary X-ray analysis of the human respiratory syncytial virus nucleocapsid protein

scientific article published on 28 October 2008

Crystallographic analysis of the binding modes of thiazoloisoindolinone non-nucleoside inhibitors to HIV-1 reverse transcriptase and comparison with modeling studies

scientific article

Crystallographic studies of shikimate binding and induced conformational changes in Mycobacterium tuberculosis shikimate kinase

scientific article published in September 2004

Design of MKC-442 (emivirine) analogues with improved activity against drug-resistant HIV mutants

scientific article

Design of non-nucleoside inhibitors of HIV-1 reverse transcriptase with improved drug resistance properties. 1.

scientific article

Design of non-nucleoside inhibitors of HIV-1 reverse transcriptase with improved drug resistance properties. 2.

scientific article

Exploiting fast detectors to enter a new dimension in room-temperature crystallography

scientific article

Expression, purification and crystallization of Aspergillus nidulans NmrA, a negative regulatory protein involved in nitrogen-metabolite repression

scientific article published on 25 October 2001

GTP cyclohydrolase II structure and mechanism

scientific article published on 22 August 2005

Generation and characterisation of recombinant FMDV antibodies: Applications for advancing diagnostic and laboratory assays

scientific article published in PLoS ONE

Glutathione facilitates enterovirus assembly by binding at a druggable pocket

scientific article published on 03 January 2020

HIV reverse transcriptase structures: designing new inhibitors and understanding mechanisms of drug resistance

scientific article

Hand-foot-and-mouth disease virus receptor KREMEN1 binds the canyon of Coxsackie Virus A10

scientific article published on 07 January 2020

Hepatitis A Virus Capsid Structure

scientific article published on 01 May 2019

Hepatitis A virus and the origins of picornaviruses

scientific article

High resolution structures of HIV-1 RT from four RT-inhibitor complexes

scientific article

High-speed fixed-target serial virus crystallography ⬇️

scientific article

In situ macromolecular crystallography using microbeams

scientific article published on 17 April 2012

Ligand-induced conformational changes and a mechanism for domain closure in Aspergillus nidulans dehydroquinate synthase

scientific article (publication date: 14 March 2003)

Lysosome sorting of β-glucocerebrosidase by LIMP-2 is targeted by the mannose 6-phosphate receptor

scientific article

Mechanism of inhibition of HIV-1 reverse transcriptase by non-nucleoside inhibitors

scientific article

Modulation of the ligand binding properties of the transcription repressor NmrA by GATA-containing DNA and site-directed mutagenesis

scientific article published on 10 November 2004

Molecular architecture and ligand recognition determinants for T4 RNA ligase

scientific article published in November 2005

More-powerful virus inhibitors from structure-based analysis of HEV71 capsid-binding molecules

scientific article

Neutralization of SARS-CoV-2 by Destruction of the Prefusion Spike

scientific article published on 19 June 2020

Novel structural features in two ZHX homeodomains derived from a systematic study of single and multiple domains

scientific article

Outrunning free radicals in room-temperature macromolecular crystallography

scientific article published on 15 June 2012

Phenylethylthiazolylthiourea (PETT) non-nucleoside inhibitors of HIV-1 and HIV-2 reverse transcriptases. Structural and biochemical analyses

scientific article

Picornavirus uncoating intermediate captured in atomic detail

scientific article

Potent neutralization of hepatitis A virus reveals a receptor mimic mechanism and the receptor recognition site

scientific article published on 10 January 2017

Rational Engineering of Recombinant Picornavirus Capsids to Produce Safe, Protective Vaccine Antigen

scientific article

Redundant Late Domain Functions of Tandem VP2 YPXL Motifs in Nonlytic Cellular Egress of Quasi-enveloped Hepatitis A Virus

scholarly article by Olga González-López et al published 1 December 2018 in Journal of Virology

Relationship of potency and resilience to drug resistant mutations for GW420867X revealed by crystal structures of inhibitor complexes for wild-type, Leu100Ile, Lys101Glu, and Tyr188Cys mutant HIV-1 reverse transcriptases

scientific article

SAT2 Foot-and-Mouth Disease Virus Structurally Modified for Increased Thermostability

scientific article published on 15 March 2017

Semi-automated microseeding of nanolitre crystallization experiments

scientific article

Structural analysis of the recognition of the negative regulator NmrA and DNA by the zinc finger from the GATA-type transcription factor AreA

scientific article

Structural and functional analysis of protective antibodies targeting the threefold plateau of enterovirus 71

scientific article published on 16 October 2020

Structural and functional insights of RANKL-RANK interaction and signaling

scientific article

Structural basis for drug resistance mechanisms for non-nucleoside inhibitors of HIV reverse transcriptase

scientific article published on 03 March 2008

Structural basis for the improved drug resistance profile of new generation benzophenone non-nucleoside HIV-1 reverse transcriptase inhibitors

scientific article

Structural basis for the neutralization of SARS-CoV-2 by an antibody from a convalescent patient

scientific article published on 31 July 2020

Structural basis for the resilience of efavirenz (DMP-266) to drug resistance mutations in HIV-1 reverse transcriptase

scientific article

Structural characterization of melatonin as an inhibitor of the Wnt deacylase Notum

scientific article published on 24 January 2020

Structural insights into mechanisms of non-nucleoside drug resistance for HIV-1 reverse transcriptases mutated at codons 101 or 138

scientific article published on 01 August 2006

Structural mechanisms of drug resistance for mutations at codons 181 and 188 in HIV-1 reverse transcriptase and the improved resilience of second generation non-nucleoside inhibitors

scientific article

Structural origins of the selectivity of the trifunctional oxygenase clavaminic acid synthase

scientific article

Structure Elucidation of Coxsackievirus A16 in Complex with GPP3 Informs a Systematic Review of Highly Potent Capsid Binders to Enteroviruses

scientific article

Structure and functionality in flavivirus NS-proteins: perspectives for drug design

scientific article

Structure determination from a single high-pressure-frozen virus crystal

scientific article published on 19 January 2013

Structure of HIV-2 reverse transcriptase at 2.35-A resolution and the mechanism of resistance to non-nucleoside inhibitors.

scientific article

Structure of Ljungan virus provides insight into genome packaging of this picornavirus.

scientific article

Structure of Staphylococcus aureus cytidine monophosphate kinase in complex with cytidine 5'-monophosphate

scientific article published on 24 July 2006

Structure of glycosylated NPC1 luminal domain C reveals insights into NPC2 and Ebola virus interactions

scientific article

Structure of human Aichi virus and implications for receptor binding

scientific article

Structure of the Nucleoprotein Binding Domain of Mokola Virus Phosphoprotein

scientific article

Structure of the Wnt signaling enhancer LYPD6 and its interactions with the Wnt coreceptor LRP6

scientific article published on 24 August 2018

Structure of the cold-shock domain protein fromNeisseria meningitidisreveals a strand-exchanged dimer

scientific article

Structure of the regulatory domain of the LysR family regulator NMB2055 (MetR-like protein) from Neisseria meningitidis

scientific article

Structure-Based in Silico Screening Identifies a Potent Ebolavirus Inhibitor from a Traditional Chinese Medicine Library

article

Structure-based energetics of protein interfaces guides foot-and-mouth disease virus vaccine design

scientific article

Structures of Coxsackievirus A16 Capsids with Native Antigenicity: Implications for Particle Expansion, Receptor Binding, and Immunogenicity

scientific article

Structures of Ebola Virus Glycoprotein Complexes with Tricyclic Antidepressant and Antipsychotic Drugs

scholarly article by Yuguang Zhao et al published 14 June 2018 in Journal of Medicinal Chemistry

Structures of R- and T-state Escherichia coli aspartokinase III. Mechanisms of the allosteric transition and inhibition by lysine

scientific article

Structures of S. aureus thymidylate kinase reveal an atypical active site configuration and an intermediate conformational state upon substrate binding

scientific article published on 7 March 2006

Structures of an alanine racemase fromBacillus anthracis(BA0252) in the presence and absence of (R)-1-aminoethylphosphonic acid (L-Ala-P)

scientific article

Structures of foot and mouth disease virus pentamers: Insight into capsid dissociation and unexpected pentamer reassociation

scientific article published on 22 September 2017

Structures of respiratory syncytial virus nucleocapsid protein from two crystal forms: details of potential packing interactions in the native helical form

scientific article

Target identification and mode of action of four chemically divergent drugs against Ebola virus infection

scientific article published on 22 December 2017

The N-glycosidase mechanism of ribosome-inactivating proteins implied by crystal structures of alpha-momorcharin

scientific article

The affinity of human RANK binding to its ligand RANKL.

scientific article

The crystal structure of NGO0477 from Neisseria gonorrhoeae reveals a novel protein fold incorporating a helix-turn-helix motif

scientific article

The human otubain2-ubiquitin structure provides insights into the cleavage specificity of poly-ubiquitin-linkages

scientific article published on 15 January 2015

The phenylmethylthiazolylthiourea nonnucleoside reverse transcriptase (RT) inhibitor MSK-076 selects for a resistance mutation in the active site of human immunodeficiency virus type 2 RT.

scientific article

The role of the light chain in the structure and binding activity of two cattle antibodies that neutralize bovine respiratory syncytial virus

scientific article published on 14 May 2019

The structure and transcriptional analysis of a global regulator from Neisseria meningitidis

scientific article

The structure of CrgA from Neisseria meningitidis reveals a new octameric assembly state for LysR transcriptional regulators

scientific article

The structure of HIV-1 reverse transcriptase complexed with 9-chloro-TIBO: lessons for inhibitor design

scientific article

The structure of NMB1585, a MarR-family regulator from Neisseria meningitidis

scientific article

The structure of a reduced form of OxyR from Neisseria meningitidis

scientific article

The structure of the negative transcriptional regulator NmrA reveals a structural superfamily which includes the short-chain dehydrogenase/reductases

scientific article

Toremifene interacts with and destabilizes the Ebola virus glycoprotein

scientific article published on 29 June 2016

Unexpected mode of engagement between enterovirus 71 and its receptor SCARB2 ⬇️

scientific article published on 10 December 2018

Unique features in the structure of the complex between HIV-1 reverse transcriptase and the bis(heteroaryl)piperazine (BHAP) U-90152 explain resistance mutations for this nonnucleoside inhibitor

scientific article

Universal detection of foot and mouth disease virus based on the conserved VP0 protein

article by Silvia Loureiro et al published 25 July 2018 in Wellcome Open Research

iASPP mediates p53 selectivity through a modular mechanism fine-tuning DNA recognition

scientific article published on 08 August 2019

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