List of works - Jiahai Shi

A novel de novo mutation in ATP1A3 and childhood-onset schizophrenia

scientific article published on September 2016

A respiratory chain controlled signal transduction cascade in the mitochondrial intermembrane space mediates hydrogen peroxide signaling

scientific article

AIFM1 mutation presenting with fatal encephalomyopathy and mitochondrial disease in an infant

scientific article published on March 2017

Clinical heterogeneity associated with KCNA1 mutations include cataplexy and nonataxic presentations

scientific article published on 22 September 2015

Crystal Structure and NMR Binding Reveal That Two Small Molecule Antagonists Target the High Affinity Ephrin-binding Channel of the EphA4 Receptor

scientific article

Dissection study on the severe acute respiratory syndrome 3C-like protease reveals the critical role of the extra domain in dimerization of the enzyme: defining the extra domain as a new target for design of highly specific protease inhibitors

scientific article

Dynamically-driven enhancement of the catalytic machinery of the SARS 3C-like protease by the S284-T285-I286/A mutations on the extra domain

scientific article

Dynamically-driven inactivation of the catalytic machinery of the SARS 3C-like protease by the N214A mutation on the extra domain

scientific article

Efficient CRISPR-Cas9 mediated gene disruption in primary erythroid progenitor cells

scientific article published on 11 March 2016

Elimination of the native structure and solubility of the hVAPB MSP domain by the Pro56Ser mutation that causes amyotrophic lateral sclerosis

scientific article

Engineered red blood cells as carriers for systemic delivery of a wide array of functional probes

scientific article

Epithelial Sodium Channel ENaC is a Modifier of the Long Term Non-progressive Phenotype Associated with F508del CFTR Mutations

scientific article published on 14 July 2017

Global discovery of erythroid long noncoding RNAs reveals novel regulators of red cell maturation

scientific article

Histones to the cytosol: exportin 7 is essential for normal terminal erythroid nuclear maturation

scientific article

Homozygous EEF1A2 mutation causes dilated cardiomyopathy, failure to thrive, global developmental delay, epilepsy and early death

scientific article

Hyperammonemia as a Presenting Feature in Two Siblings with FBXL4 Variants.

scientific article

Identification, recombinant production and structural characterization of four silk proteins from the Asiatic honeybee Apis cerana

scientific article published on 3 April 2008

JAK2 V617F stimulates proliferation of erythropoietin-dependent erythroid progenitors and delays their differentiation by activating Stat1 and other nonerythroid signaling pathways

scientific article published on 26 July 2016

Mechanism for Controlling the Dimer-Monomer Switch and Coupling Dimerization to Catalysis of the Severe Acute Respiratory Syndrome Coronavirus 3C-Like Protease

scientific article

Muscleblind-like 1 (Mbnl1) regulates pre-mRNA alternative splicing during terminal erythropoiesis

scientific article

Mutations in the substrate binding glycine-rich loop of the mitochondrial processing peptidase-α protein (PMPCA) cause a severe mitochondrial disease

scientific article published on May 2016

NMR structure and dynamics of human ephrin-B2 ectodomain: the functionally critical C-D and G-H loops are highly dynamic in solution

scientific article

Novel mutation in CNTNAP1 results in congenital hypomyelinating neuropathy

scientific article published on 26 September 2016

Resurrecting abandoned proteins with pure water: CD and NMR studies of protein fragments solubilized in salt-free water

scientific article

SLC6A1 Mutation and Ketogenic Diet in Epilepsy With Myoclonic-Atonic Seizures

scientific article published on 28 July 2016

Structural Characterization of the EphA4-Ephrin-B2 Complex Reveals New Features Enabling Eph-Ephrin Binding Promiscuity

scientific article

Structural characterization of the human Nogo-A functional domains. Solution structure of Nogo-40, a Nogo-66 receptor antagonist enhancing injured spinal cord regeneration

scientific article

Structural characterization reveals that viperin is a radical S-adenosyl-L-methionine (SAM) enzyme

scientific article

Structural, stability, dynamic and binding properties of the ALS-causing T46I mutant of the hVAPB MSP domain as revealed by NMR and MD simulations

scientific article

The catalysis of the SARS 3C-like protease is under extensive regulation by its extra domain

scientific article published in March 2006

Transcriptional divergence and conservation of human and mouse erythropoiesis

scientific article published on 03 March 2014

Unique structure and dynamics of the EphA5 ligand binding domain mediate its binding specificity as revealed by X-ray crystallography, NMR and MD simulations

scientific article

Wdr26 regulates nuclear condensation in developing erythroblasts

scientific article published on 01 January 2020

X-linked macrocytic dyserythropoietic anemia in females with an ALAS2 mutation

scientific article

List of works by Jiahai Shi

A novel de novo mutation in ATP1A3 and childhood-onset schizophrenia

A respiratory chain controlled signal transduction cascade in the mitochondrial intermembrane space mediates hydrogen peroxide signaling

AIFM1 mutation presenting with fatal encephalomyopathy and mitochondrial disease in an infant

Clinical heterogeneity associated with KCNA1 mutations include cataplexy and nonataxic presentations

Crystal Structure and NMR Binding Reveal That Two Small Molecule Antagonists Target the High Affinity Ephrin-binding Channel of the EphA4 Receptor

Dissection study on the severe acute respiratory syndrome 3C-like protease reveals the critical role of the extra domain in dimerization of the enzyme: defining the extra domain as a new target for design of highly specific protease inhibitors

Dynamically-driven enhancement of the catalytic machinery of the SARS 3C-like protease by the S284-T285-I286/A mutations on the extra domain

Dynamically-driven inactivation of the catalytic machinery of the SARS 3C-like protease by the N214A mutation on the extra domain

Efficient CRISPR-Cas9 mediated gene disruption in primary erythroid progenitor cells

Elimination of the native structure and solubility of the hVAPB MSP domain by the Pro56Ser mutation that causes amyotrophic lateral sclerosis

Engineered red blood cells as carriers for systemic delivery of a wide array of functional probes

Epithelial Sodium Channel ENaC is a Modifier of the Long Term Non-progressive Phenotype Associated with F508del CFTR Mutations

Global discovery of erythroid long noncoding RNAs reveals novel regulators of red cell maturation

Histones to the cytosol: exportin 7 is essential for normal terminal erythroid nuclear maturation

Homozygous EEF1A2 mutation causes dilated cardiomyopathy, failure to thrive, global developmental delay, epilepsy and early death

Hyperammonemia as a Presenting Feature in Two Siblings with FBXL4 Variants.

Identification, recombinant production and structural characterization of four silk proteins from the Asiatic honeybee Apis cerana

JAK2 V617F stimulates proliferation of erythropoietin-dependent erythroid progenitors and delays their differentiation by activating Stat1 and other nonerythroid signaling pathways

Mechanism for Controlling the Dimer-Monomer Switch and Coupling Dimerization to Catalysis of the Severe Acute Respiratory Syndrome Coronavirus 3C-Like Protease

Muscleblind-like 1 (Mbnl1) regulates pre-mRNA alternative splicing during terminal erythropoiesis

Mutations in the substrate binding glycine-rich loop of the mitochondrial processing peptidase-α protein (PMPCA) cause a severe mitochondrial disease

NMR structure and dynamics of human ephrin-B2 ectodomain: the functionally critical C-D and G-H loops are highly dynamic in solution

Novel mutation in CNTNAP1 results in congenital hypomyelinating neuropathy

Resurrecting abandoned proteins with pure water: CD and NMR studies of protein fragments solubilized in salt-free water

SLC6A1 Mutation and Ketogenic Diet in Epilepsy With Myoclonic-Atonic Seizures

Structural Characterization of the EphA4-Ephrin-B2 Complex Reveals New Features Enabling Eph-Ephrin Binding Promiscuity

Structural characterization of the human Nogo-A functional domains. Solution structure of Nogo-40, a Nogo-66 receptor antagonist enhancing injured spinal cord regeneration

Structural characterization reveals that viperin is a radical S-adenosyl-L-methionine (SAM) enzyme

Structural, stability, dynamic and binding properties of the ALS-causing T46I mutant of the hVAPB MSP domain as revealed by NMR and MD simulations

The catalysis of the SARS 3C-like protease is under extensive regulation by its extra domain

Transcriptional divergence and conservation of human and mouse erythropoiesis

Unique structure and dynamics of the EphA5 ligand binding domain mediate its binding specificity as revealed by X-ray crystallography, NMR and MD simulations

Wdr26 regulates nuclear condensation in developing erythroblasts

X-linked macrocytic dyserythropoietic anemia in females with an ALAS2 mutation