List of works - Chiara Agrati

"Immuknow" to measurement of cell-mediated immunity in renal transplant recipients undergoing short-term evaluation

scientific article published on May 2011

A Novel 8-Color Flow Cytometry Panel to Study Activation, Maturation and Senescence of CD4 and CD8 T Lymphocytes in HIV-Infected Individuals at Different Stages of Disease

article

A new procedure to analyze polymorphonuclear myeloid derived suppressor cells in cryopreserved samples cells by flow cytometry

scientific article published on 30 August 2018

Accumulation of dysfunctional effector CD8+T cells in the liver of patients with chronic HCV infection

Activation of Vgamma9Vdelta2 T cells by non-peptidic antigens induces the inhibition of subgenomic HCV replication

scientific article published on 16 December 2005

Acute human immunodeficiency virus replication causes a rapid and persistent impairment of Vgamma9Vdelta2 T cells in chronically infected patients undergoing structured treatment interruption

scientific article published on 16 August 2002

Administration of PLP139-151 Primes T Cells Distinct from Those Spontaneously Responsive In Vitro to This Antigen

scientific article published on 01 May 2008

Anti-severe acute respiratory syndrome coronavirus immune responses: the role played by V gamma 9V delta 2 T cells

scientific article published on 27 March 2006

Antiviral reactivities of gammadelta T cells

scientific article

Association of profoundly impaired immune competence in H1N1v-infected patients with a severe or fatal clinical course

scientific article

Bone Marrow CD34+ Progenitor Cells from HIV-Infected Patients Show an Impaired T Cell Differentiation Potential Related to Proinflammatory Cytokines.

scientific article published on 26 January 2017

Bone marrow CD34+ progenitor cells may harbour HIV-DNA even in successfully treated patients.

scientific article published on 11 November 2014

Brain localization of Kaposi's sarcoma in a patient treated by combination antiretroviral therapy

scientific article

CD3zeta down-modulation may explain Vgamma9Vdelta2 T lymphocyte anergy in HIV-infected patients

scientific article

Cellular and humoral cross-immunity against two H3N2v influenza strains in presumably unexposed healthy and HIV-infected subjects.

scientific article

Cellular and humoral immune responses to pandemic influenza vaccine in healthy and in highly active antiretroviral therapy-treated HIV patients

scientific article

Chronic HIV-infected patients show an impaired dendritic cells differentiation of bone marrow CD34⁺ cells

scientific article published on December 2013

Co-stimulatory molecule CD80 expression may correlate with anti-HCV treatment outcome

scientific article published on 30 August 2010

Coordinate induction of IFN-alpha and -gamma by SARS-CoV also in the absence of virus replication.

scientific article

Corrigendum to "Multicentre Harmonisation of a Six-Colour Flow Cytometry Panel for Naïve/Memory T Cell Immunomonitoring"

scientific article published on 10 August 2020

Cross-subtype immunity against avian influenza in persons recently vaccinated for influenza

scientific article

Cutting edge: TGF-beta1 and IL-15 Induce FOXP3+ gammadelta regulatory T cells in the presence of antigen stimulation

scientific article

Dendritic cells activation is associated with sustained virological response to telaprevir treatment of HCV-infected patients.

scientific article

Diagnostic performances of clinical laboratory tests using Triton X-100 to reduce the biohazard associated with routine testing of Ebola virus-infected patients

scientific article published on 6 June 2015

Different Cytokine Production and Effector/Memory Dynamics of αβ+ or γδ+ T-Cell Subsets in the Peripheral Blood of Patients with Active Pulmonary Tuberculosis ⬇️

scientific article published on September 1, 2003

Different features of Vδ2 T and NK cells in fatal and non-fatal human Ebola infections

scientific article

Do human T cells respond to M tuberculosis protein antigens?

scholarly article by Rita Casetti et al published 1 December 2008 in Blood

Early ART in primary HIV infection may also preserve lymphopoiesis capability in circulating haematopoietic progenitor cells: a case report.

scientific article published on 20 January 2015

Expansion of pre-terminally differentiated CD8 T cells in chronic HIV-positive patients presenting a rapid viral rebound during structured treatment interruption

scientific article published in December 2002

Expression of muscarinic m2 receptor mRNA in dorsal root ganglia of neonatal rat.

scientific article

GB virus type C cross-reactivity in clinical samples with a low hepatitis C virus antibody positive response

scientific article published on 01 February 2019

Granulocytic Myeloid-Derived Suppressor Cells Increased in Early Phases of Primary HIV Infection Depending on TRAIL Plasma Level

scientific article published on 2 January 2017

HCV-DAA therapy impacts on extracellular vesicles miRNAs content and on their immunomodulating properties

scientific article published on 22 January 2018

HIV impairs CD34+-derived monocytic precursor differentiation into functional dendritic cells

scientific article

HIV infection of monocytes-derived dendritic cells inhibits Vγ9Vδ2 T cells functions

scientific article

HIV-Specific CD8 T Cells Producing CCL-4 Are Associated With Worse Immune Reconstitution During Chronic Infection

scientific article published on 7 April 2017

HLA-E Up-Regulation Induced by HIV Infection May Directly Contribute to CD94-Mediated Impairment of NK Cells

article

Highly active antiretroviral therapy restores CD4+ Vbeta T-cell repertoire in patients with primary acute HIV infection but not in treatment-naive HIV+ patients with severe chronic infection

scientific article published in March 2004

Human Zika infection induces a reduction of IFN-γ producing CD4 T-cells and a parallel expansion of effector Vδ2 T-cells

scientific article published on 24 July 2017

IL-18 and Stem Cell Factor affect hematopoietic progenitor cells in HIV-infected patients treated during primary HIV infection

scientific article published on 8 January 2018

Impact of ART on dynamics of growth factors and cytokines in primary HIV infection

scientific article published on 19 September 2019

In HIV-infected patients, some differential alterations of CD4 and CD8 T cell homeostasis may not be restored by >=7 years of highly active antiretroviral therapy, in spite of good CD4 T cell repopulation

article

In HIV-positive patients, myeloid-derived suppressor cells induce T-cell anergy by suppressing CD3ζ expression through ELF-1 inhibition.

scientific article published on 9 September 2015

In HIV/HCV co-infected patients T regulatory and myeloid-derived suppressor cells persist after successful treatment with directly acting antivirals

scientific article

In Human Immunodeficiency Virus primary infection, early combined antiretroviral therapy reduced γδ T-cell activation but failed to restore their polyfunctionality

scientific article published on 08 July 2019

In vivo effects of zoledronic acid on peripheral gammadelta T lymphocytes in early breast cancer patients

scientific article published on 6 May 2008

In vivo interferon-alpha/ribavirin treatment modulates Vγ9Vδ2 T-cell function during chronic HCV infection

scientific article published on 11 January 2013

Influence of GB virus type C and HIV coinfection on gamma delta T cells

scientific article published on January 2005

Influenza Pandemics, Immune Cross‐Reactivity, and Pandemic Control Strategies

scientific article published in 2008

Interferon-α improves phosphoantigen-induced Vγ9Vδ2 T-cells interferon-γ production during chronic HCV infection

scientific article (publication date: 2012)

Interferon‐γ–Mediated Antiviral Immunity against Orthopoxvirus Infection Is Provided by γδ T Cells

scientific article published in 2006

Intrahepatic Vγ9Vδ2 T-cells from HCV-infected patients show an exhausted phenotype but can inhibit HCV replication.

scientific article

Intrahepatic natural immunity and HCV immunopathogenesis.

scientific article

Longitudinal characterization of dysfunctional T cell-activation during human acute Ebola infection.

scientific article published on 31 March 2016

Measles Cases during Ebola Outbreak, West Africa, 2013-2106.

scientific article

Modulation of polyfunctional HIV-specific CD8 T cells in patients responding differently to antiretroviral therapy.

scientific article published in April 2014

Molecular characterization of hepatitis A outbreak in the province of Rome, Lazio region, Italy, January-July 2013.

scientific article published on 28 January 2014

Molecular mechanisms of Ebola virus pathogenesis: focus on cell death

scientific article

Multicentre Harmonisation of a Six-Colour Flow Cytometry Panel for Naïve/Memory T Cell Immunomonitoring

scientific article published on 12 April 2020

Multicompartment vectors as novel drug delivery systems: selective activation of Tγδ lymphocytes after zoledronic acid delivery

article published in 2011

Murine hepatocyte cell lines promote expansion and differentiation of NK cells from stem cell precursors

scientific article published on June 2004

Myeloid Derived Suppressor Cells Expansion Persists After Early ART and May Affect CD4 T Cell Recovery

Myeloid-Derived Suppressor Cells Specifically Suppress IFN-γ Production and Antitumor Cytotoxic Activity of Vδ2 T Cells.

scientific article published on 6 June 2018

Naïve/Effector CD4 T cell ratio as a useful predictive marker of immune reconstitution in late presenter HIV patients: A multicenter study

scientific article published on 23 December 2019

Non-Pathogenic Mycobacterium smegmatis Induces the Differentiation of Human Monocytes Directly into Fully Mature Dendritic Cells

Occupational transmission of an Orthopoxvirus infection during an outbreak in a colony of Macaca tonkeana in Lazio Region, Italy, 2015.

scientific article published on 7 March 2018

P-glycoprotein expression by peripheral blood mononuclear cells from human immunodeficiency virus-infected patients is independent from response to highly active antiretroviral therapy

scientific article published on January 2003

Persistent gamma delta T-cell dysfunction in HCV/HIV co-infection despite direct-acting antiviral therapy-induced cure

scientific article published on 12 February 2020

Plasma trough concentrations of antiretrovirals in HIV-infected persons treated with direct-acting antiviral agents for hepatitis C in the real world

scientific article published on 2 November 2017

Primary and Chronic HIV Infection Differently Modulates Mucosal Vδ1 and Vδ2 T-Cells Differentiation Profile and Effector Functions.

scientific article published on 18 June 2015

Steatosis and intrahepatic lymphocyte recruitment in hepatitis C virus transgenic mice

scientific article published on June 2004

T-Cell response profiling to biological threat agents including the SARS coronavirus

scientific article published in July 2005

The Loss of CMV-Specific CD27 − T-Cell Effectors in a Patient with Recurrences of CMV Retinitis Is Independent of HIV-1 Viremia

article

The basal activation state of DC subsets correlates with anti-HCV treatment outcome in HCV/HIV co-infected patients

scientific article published on 3 December 2010

UPLC-MS/MS method for the simultaneous quantification of sofosbuvir, sofosbuvir metabolite (GS-331007) and daclatasvir in plasma of HIV/HCV co-infected patients

scientific article published on 12 December 2017

Unawareness of HCV serostatus among persons newly diagnosed with HIV

scientific article published on 06 February 2019

Unexpected human cases of cutaneous anthrax in Latium region, Italy, August 2017: integrated human-animal investigation of epidemiological, clinical, microbiological and ecological factors

scientific article published on 01 June 2019

Unique human immune signature of Ebola virus disease in Guinea

scientific article

Vgamma9Vdelta2 T cell-mediated non-cytolytic antiviral mechanisms and their potential for cell-based therapy

scientific article

Vγ9Vδ2 T-Cell Polyfunctionality Is Differently Modulated in HAART-Treated HIV Patients according to CD4 T-Cell Count

scientific article published on 10 July 2015

ZIKV Infection Induces an Inflammatory Response but Fails to Activate Types I, II, and III IFN Response in Human PBMC.

scientific article

Zoledronic acid and interleukin-2 treatment improves immunocompetence in HIV-infected persons by activating Vgamma9Vdelta2 T cells

scientific article published in March 2009

List of works by Chiara Agrati

"Immuknow" to measurement of cell-mediated immunity in renal transplant recipients undergoing short-term evaluation

A Novel 8-Color Flow Cytometry Panel to Study Activation, Maturation and Senescence of CD4 and CD8 T Lymphocytes in HIV-Infected Individuals at Different Stages of Disease

A new procedure to analyze polymorphonuclear myeloid derived suppressor cells in cryopreserved samples cells by flow cytometry

Accumulation of dysfunctional effector CD8+T cells in the liver of patients with chronic HCV infection

Activation of Vgamma9Vdelta2 T cells by non-peptidic antigens induces the inhibition of subgenomic HCV replication

Acute human immunodeficiency virus replication causes a rapid and persistent impairment of Vgamma9Vdelta2 T cells in chronically infected patients undergoing structured treatment interruption

Administration of PLP139-151 Primes T Cells Distinct from Those Spontaneously Responsive In Vitro to This Antigen

Anti-severe acute respiratory syndrome coronavirus immune responses: the role played by V gamma 9V delta 2 T cells

Antiviral reactivities of gammadelta T cells

Association of profoundly impaired immune competence in H1N1v-infected patients with a severe or fatal clinical course

Bone Marrow CD34+ Progenitor Cells from HIV-Infected Patients Show an Impaired T Cell Differentiation Potential Related to Proinflammatory Cytokines.

Bone marrow CD34+ progenitor cells may harbour HIV-DNA even in successfully treated patients.

Brain localization of Kaposi's sarcoma in a patient treated by combination antiretroviral therapy

CD3zeta down-modulation may explain Vgamma9Vdelta2 T lymphocyte anergy in HIV-infected patients

Cellular and humoral cross-immunity against two H3N2v influenza strains in presumably unexposed healthy and HIV-infected subjects.

Cellular and humoral immune responses to pandemic influenza vaccine in healthy and in highly active antiretroviral therapy-treated HIV patients

Chronic HIV-infected patients show an impaired dendritic cells differentiation of bone marrow CD34⁺ cells

Co-stimulatory molecule CD80 expression may correlate with anti-HCV treatment outcome

Coordinate induction of IFN-alpha and -gamma by SARS-CoV also in the absence of virus replication.

Corrigendum to "Multicentre Harmonisation of a Six-Colour Flow Cytometry Panel for Naïve/Memory T Cell Immunomonitoring"

Cross-subtype immunity against avian influenza in persons recently vaccinated for influenza

Cutting edge: TGF-beta1 and IL-15 Induce FOXP3+ gammadelta regulatory T cells in the presence of antigen stimulation

Dendritic cells activation is associated with sustained virological response to telaprevir treatment of HCV-infected patients.

Diagnostic performances of clinical laboratory tests using Triton X-100 to reduce the biohazard associated with routine testing of Ebola virus-infected patients

Different Cytokine Production and Effector/Memory Dynamics of αβ+ or γδ+ T-Cell Subsets in the Peripheral Blood of Patients with Active Pulmonary Tuberculosis ⬇️

Different features of Vδ2 T and NK cells in fatal and non-fatal human Ebola infections

Do human T cells respond to M tuberculosis protein antigens?

Early ART in primary HIV infection may also preserve lymphopoiesis capability in circulating haematopoietic progenitor cells: a case report.

Expansion of pre-terminally differentiated CD8 T cells in chronic HIV-positive patients presenting a rapid viral rebound during structured treatment interruption

Expression of muscarinic m2 receptor mRNA in dorsal root ganglia of neonatal rat.

GB virus type C cross-reactivity in clinical samples with a low hepatitis C virus antibody positive response

Granulocytic Myeloid-Derived Suppressor Cells Increased in Early Phases of Primary HIV Infection Depending on TRAIL Plasma Level

HCV-DAA therapy impacts on extracellular vesicles miRNAs content and on their immunomodulating properties

HIV impairs CD34+-derived monocytic precursor differentiation into functional dendritic cells

HIV infection of monocytes-derived dendritic cells inhibits Vγ9Vδ2 T cells functions

HIV-Specific CD8 T Cells Producing CCL-4 Are Associated With Worse Immune Reconstitution During Chronic Infection

HLA-E Up-Regulation Induced by HIV Infection May Directly Contribute to CD94-Mediated Impairment of NK Cells

Highly active antiretroviral therapy restores CD4+ Vbeta T-cell repertoire in patients with primary acute HIV infection but not in treatment-naive HIV+ patients with severe chronic infection

Human Zika infection induces a reduction of IFN-γ producing CD4 T-cells and a parallel expansion of effector Vδ2 T-cells

IL-18 and Stem Cell Factor affect hematopoietic progenitor cells in HIV-infected patients treated during primary HIV infection

Impact of ART on dynamics of growth factors and cytokines in primary HIV infection

In HIV-infected patients, some differential alterations of CD4 and CD8 T cell homeostasis may not be restored by >=7 years of highly active antiretroviral therapy, in spite of good CD4 T cell repopulation

In HIV-positive patients, myeloid-derived suppressor cells induce T-cell anergy by suppressing CD3ζ expression through ELF-1 inhibition.

In HIV/HCV co-infected patients T regulatory and myeloid-derived suppressor cells persist after successful treatment with directly acting antivirals

In Human Immunodeficiency Virus primary infection, early combined antiretroviral therapy reduced γδ T-cell activation but failed to restore their polyfunctionality

In vivo effects of zoledronic acid on peripheral gammadelta T lymphocytes in early breast cancer patients

In vivo interferon-alpha/ribavirin treatment modulates Vγ9Vδ2 T-cell function during chronic HCV infection

Influence of GB virus type C and HIV coinfection on gamma delta T cells

Influenza Pandemics, Immune Cross‐Reactivity, and Pandemic Control Strategies

Interferon-α improves phosphoantigen-induced Vγ9Vδ2 T-cells interferon-γ production during chronic HCV infection

Interferon‐γ–Mediated Antiviral Immunity against Orthopoxvirus Infection Is Provided by γδ T Cells

Intrahepatic Vγ9Vδ2 T-cells from HCV-infected patients show an exhausted phenotype but can inhibit HCV replication.

Intrahepatic natural immunity and HCV immunopathogenesis.

Longitudinal characterization of dysfunctional T cell-activation during human acute Ebola infection.

Measles Cases during Ebola Outbreak, West Africa, 2013-2106.

Modulation of polyfunctional HIV-specific CD8 T cells in patients responding differently to antiretroviral therapy.

Molecular characterization of hepatitis A outbreak in the province of Rome, Lazio region, Italy, January-July 2013.

Molecular mechanisms of Ebola virus pathogenesis: focus on cell death

Multicentre Harmonisation of a Six-Colour Flow Cytometry Panel for Naïve/Memory T Cell Immunomonitoring

Multicompartment vectors as novel drug delivery systems: selective activation of Tγδ lymphocytes after zoledronic acid delivery

Murine hepatocyte cell lines promote expansion and differentiation of NK cells from stem cell precursors

Myeloid Derived Suppressor Cells Expansion Persists After Early ART and May Affect CD4 T Cell Recovery

Myeloid-Derived Suppressor Cells Specifically Suppress IFN-γ Production and Antitumor Cytotoxic Activity of Vδ2 T Cells.

Naïve/Effector CD4 T cell ratio as a useful predictive marker of immune reconstitution in late presenter HIV patients: A multicenter study

Non-Pathogenic Mycobacterium smegmatis Induces the Differentiation of Human Monocytes Directly into Fully Mature Dendritic Cells

Occupational transmission of an Orthopoxvirus infection during an outbreak in a colony of Macaca tonkeana in Lazio Region, Italy, 2015.

P-glycoprotein expression by peripheral blood mononuclear cells from human immunodeficiency virus-infected patients is independent from response to highly active antiretroviral therapy

Persistent gamma delta T-cell dysfunction in HCV/HIV co-infection despite direct-acting antiviral therapy-induced cure

Plasma trough concentrations of antiretrovirals in HIV-infected persons treated with direct-acting antiviral agents for hepatitis C in the real world

Primary and Chronic HIV Infection Differently Modulates Mucosal Vδ1 and Vδ2 T-Cells Differentiation Profile and Effector Functions.

Steatosis and intrahepatic lymphocyte recruitment in hepatitis C virus transgenic mice

T-Cell response profiling to biological threat agents including the SARS coronavirus

The Loss of CMV-Specific CD27 − T-Cell Effectors in a Patient with Recurrences of CMV Retinitis Is Independent of HIV-1 Viremia

The basal activation state of DC subsets correlates with anti-HCV treatment outcome in HCV/HIV co-infected patients

UPLC-MS/MS method for the simultaneous quantification of sofosbuvir, sofosbuvir metabolite (GS-331007) and daclatasvir in plasma of HIV/HCV co-infected patients

Unawareness of HCV serostatus among persons newly diagnosed with HIV

Unexpected human cases of cutaneous anthrax in Latium region, Italy, August 2017: integrated human-animal investigation of epidemiological, clinical, microbiological and ecological factors

Unique human immune signature of Ebola virus disease in Guinea

Vgamma9Vdelta2 T cell-mediated non-cytolytic antiviral mechanisms and their potential for cell-based therapy