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List of works by Massimo Palmarini

"Frozen evolution" of an RNA virus suggests accidental release as a potential cause of arbovirus re-emergence

scientific article published on 28 April 2020

"Ménage à Trois": the evolutionary interplay between JSRV, enJSRVs and domestic sheep

scientific article

134 A cellular restriction factor blocking replication of an emerging bunyavirus in human cells: clues for cross-species barriers?

scientific article

A Moloney murine leukemia virus driven by the Jaagsiekte sheep retrovirus enhancers shows enhanced specificity for infectivity in lung epithelial cells

scientific article published on December 2005

A large animal model to evaluate the effects of Hsp90 inhibitors for the treatment of lung adenocarcinoma.

scientific article published on 24 October 2007

A new era of virus bioinformatics

scientific article published on 08 May 2018

A paradigm for virus-host coevolution: sequential counter-adaptations between endogenous and exogenous retroviruses

scientific article (publication date: November 2007)

A phosphatidylinositol 3-kinase docking site in the cytoplasmic tail of the Jaagsiekte sheep retrovirus transmembrane protein is essential for envelope-induced transformation of NIH 3T3 cells

scientific article published on November 2001

A plasmid DNA-launched SARS-CoV-2 reverse genetics system and coronavirus toolkit for COVID-19 research

scientific article

A prenylated dsRNA sensor protects against severe COVID-19

scientific article

A single amino acid substitution in a segment of the CA protein within Gag that has similarity to human immunodeficiency virus type 1 blocks infectivity of a human endogenous retrovirus K provirus in the human genome

scientific article

A synthetic biology approach for a vaccine platform against known and newly emerging serotypes of bluetongue virus

scientific article published on 20 August 2014

A veterinary twist on pathogen biology

scientific article published in February 2007

An accessory open reading frame (orf-x) of jaagsiekte sheep retrovirus is conserved between different virus isolates

scientific article published on January 2000

Analysis of integration sites of Jaagsiekte sheep retrovirus in ovine pulmonary adenocarcinoma

scientific article published on August 2004

Application of next generation sequencing in mammalian embryogenomics: Lessons learned from endogenous betaretroviruses of sheep ⬇️

scientific article (publication date: September 2012)

Association of Country Income Level With the Characteristics and Outcomes of Critically Ill Patients Hospitalized With Acute Kidney Injury and COVID-19

scientific article published in 2023

Association of RON tyrosine kinase with the Jaagsiekte sheep retrovirus envelope glycoprotein

scientific article published on 28 February 2006

Association of jaagsiekte sheep retrovirus with pulmonary carcinoma in Sardinian moufflon (Ovis musimon).

scientific article published on August 2001

Author Correction: Genomic epidemiology reveals multiple introductions of SARS-CoV-2 from mainland Europe into Scotland ⬇️

correction of a scholarly article

Bluetongue Virus NS4 Protein Is an Interferon Antagonist and a Determinant of Virus Virulence

scientific article

Bluetongue virus serotype 27: detection and characterization of two novel variants in Corsica, France.

scientific article published on 19 July 2016

Bluetongue virus spread in Europe is a consequence of climatic, landscape and vertebrate host factors as revealed by phylogeographic inference

scientific article published in October 2017

Bluetongue: a rich history filled with many landmarks in virology……and more to be uncovered!

scientific article published in March 2014

COVID-19 symptoms at hospital admission vary with age and sex: results from the ISARIC prospective multinational observational study

scientific article

Cellular Differentiation and Proliferation in the Ovine Lung during Gestation and Early Postnatal Development ⬇️

scientific article published on January 26, 2013

Characterisation of in-hospital complications associated with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol UK: a prospective, multicentre cohort study

scientific article published in 2021

Characterization of a second open reading frame in genome segment 10 of bluetongue virus

scientific article published on 19 August 2015

Co-infections, secondary infections, and antimicrobial use in patients hospitalised with COVID-19 during the first pandemic wave from the ISARIC WHO CCP-UK study: a multicentre, prospective cohort study

scientific article published in 2021

Coevolution of endogenous betaretroviruses of sheep and their host

scientific article

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms

scientific article published on 15 October 2020

Determinants of bluetongue virus virulence in murine models of disease

scientific article published on 24 August 2011

Development and validation of the ISARIC 4C Deterioration model for adults hospitalised with COVID-19: a prospective cohort study

scientific article published in 2021

Direct transformation of rodent fibroblasts by jaagsiekte sheep retrovirus DNA

scholarly article

DisCVR: Rapid viral diagnosis from high-throughput sequencing data

scientific article published on 01 July 2019

DisCVR: Rapid viral diagnosis from high-throughput sequencing data

scientific article published on 24 January 2019

Drosophila melanogaster as a model organism for bluetongue virus replication and tropism

scientific article

Endogenous betaretroviruses of sheep: teaching new lessons in retroviral interference and adaptation

scientific article published on January 2004

Endogenous retroviruses in trophoblast differentiation and placental development

scientific article published in October 2010

Endogenous retroviruses of sheep: a model system for understanding physiological adaptation to an evolving ruminant genome

scientific article published on 01 January 2010

Endogenous retroviruses of sheep: a model system for understanding physiological adaptation to an evolving ruminant genome.

scientific article

Endogenous retroviruses regulate periimplantation placental growth and differentiation

scholarly article

Endogenous retroviruses related to jaagsiekte sheep retrovirus

scientific article

Envelope-induced cell transformation by ovine betaretroviruses

scientific article

Enzootic intranasal tumour of goats in Italy

article

Epithelial tumour cells in the lungs of sheep with pulmonary adenomatosis are major sites of replication for Jaagsiekte retrovirus ⬇️

scientific article published on November 1, 1995

Evidence for a protein related immunologically to the jaagsiekte sheep retrovirus in some human lung tumours

scientific article published on August 2000

Expression of Endogenous Betaretroviruses in the Ovine Uterus: Effects of Neonatal Age, Estrous Cycle, Pregnancy, and Progesterone ⬇️

scientific article published on December 1, 2001

Expression of the jaagsiekte sheep retrovirus envelope glycoprotein is sufficient to induce lung tumors in sheep

scientific article

Follicular dendritic cell disruption as a novel mechanism of virus-induced immunosuppression

scientific article published on 26 September 2016

Friendly viruses: the special relationship between endogenous retroviruses and their host

scientific article published in October 2009

Fundamental properties of the mammalian innate immune system revealed by multispecies comparison of type I interferon responses.

scientific article published on 18 December 2017

Genome Sequences of Five African Swine Fever Virus Genotype IX Isolates from Domestic Pigs in Uganda

scientific article published on 04 October 2018

Genomic epidemiology reveals multiple introductions of SARS-CoV-2 from mainland Europe into Scotland

scholarly article

HNF-3beta is a critical factor for the expression of the Jaagsiekte sheep retrovirus long terminal repeat in type II pneumocytes but not in Clara cells

scientific article

Heparan Sulfate Proteoglycan Is an Important Attachment Factor for Cell Entry of Akabane and Schmallenberg Viruses

scientific article published on 24 May 2017

Host species barriers to Jaagsiekte sheep retrovirus replication and carcinogenesis.

scientific article published on 31 July 2013

Identification and Characterization of a Novel Non-Structural Protein of Bluetongue Virus ⬇️

scientific article published on December 29, 2011

Immunophenotyping of Sheep Paraffin-Embedded Peripheral Lymph Nodes

scientific article published on 11 December 2018

Immunophenotyping of inflammatory cells associated with Schmallenberg virus infection of the central nervous system of ruminants.

scientific article

Implementation of corticosteroids in treatment of COVID-19 in the ISARIC WHO Clinical Characterisation Protocol UK: prospective, cohort study

scientific article published in 2022

In memoriam--Richard M. Elliott (1954-2015)

scientific article

In vitro infection of ovine cell lines by Jaagsiekte sheep retrovirus.

scientific article published on December 1999

In vitro selection of Remdesivir resistance suggests evolutionary predictability of SARS-CoV-2

scientific article published on 17 September 2021

In vivo tumorigenesis by Jaagsiekte sheep retrovirus (JSRV) requires Y590 in Env TM, but not full-length orfX open reading frame

scientific article

Infection of lung epithelial cells and induction of pulmonary adenocarcinoma is not the most common outcome of naturally occurring JSRV infection during the commercial lifespan of sheep

scientific article published on 01 July 2005

Interplay between ovine bone marrow stromal cell antigen 2/tetherin and endogenous retroviruses

scientific article

Introduction : Potential applications of pathogen genomics.

scientific article published in April 2016

Isolation of an infectious endogenous retrovirus in a proportion of live attenuated vaccines for pets

scientific article

Jaagsiekte retrovirus establishes a disseminated infection of the lymphoid tissues of sheep affected by pulmonary adenomatosis

scientific article published in December 1996

Jaagsiekte retrovirus is widely distributed both in T and B lymphocytes and in mononuclear phagocytes of sheep with naturally and experimentally acquired pulmonary adenomatosis

scientific article

Jaagsiekte sheep retrovirus is necessary and sufficient to induce a contagious lung cancer in sheep

scientific article

Jaagsiekte sheep retrovirus is not detected in human lung adenocarcinomas expressing antigens related to the Gag polyprotein of betaretroviruses

scientific article published on 24 September 2007

Lack of a specific immune response against a recombinant capsid protein of Jaagsiekte sheep retrovirus in sheep and goats naturally affected by enzootic nasal tumour or sheep pulmonary adenomatosis

scientific article published in February 1998

Lack of schmallenberg virus in ruminant brain tissues archived from 1961 to 2010 in Germany

scientific article published on 06 December 2013

Late Ebola virus relapse causing meningoencephalitis: a case report

scientific article

Late viral interference induced by transdominant Gag of an endogenous retrovirus

scholarly article

Lung adenocarcinoma originates from retrovirus infection of proliferating type 2 pneumocytes during pulmonary post-natal development or tissue repair

scientific article

Mechanisms of late restriction induced by an endogenous retrovirus.

scientific article published on 15 August 2007

Molecular biology of jaagsiekte sheep retrovirus

scientific article (publication date: 2003)

Molecular cloning and functional analysis of three type D endogenous retroviruses of sheep reveal a different cell tropism from that of the highly related exogenous jaagsiekte sheep retrovirus

scientific article

Multiple genome segments determine virulence of bluetongue virus serotype 8

scientific article published on 11 March 2015

Multitasking: Making the Most out of the Retroviral Envelope ⬇️

scientific article published on August 2, 2010

Mutations in the Schmallenberg Virus Gc Glycoprotein Facilitate Cellular Protein Synthesis Shutoff and Restore Pathogenicity of NSs Deletion Mutants in Mice

scientific article published on 16 March 2016

Mutations that adapt SARS-CoV-2 to mink or ferret do not increase fitness in the human airway

scientific article published on 19 January 2022

NSs protein of Schmallenberg virus counteracts the antiviral response of the cell by inhibiting its transcriptional machinery

scientific article published on 14 May 2014

Non-steroidal anti-inflammatory drug use and outcomes of COVID-19 in the ISARIC Clinical Characterisation Protocol UK cohort: a matched, prospective cohort study

scientific article published in 2021

Nonstructural Protein NSs of Schmallenberg Virus Is Targeted to the Nucleolus and Induces Nucleolar Disorganization

scientific article

Ovine endogenous betaretroviruses (enJSRVs) and placental morphogenesis

scientific article

PCR-based detection and partial characterization of a retrovirus associated with contagious intranasal tumors of sheep and goats

scientific article

Pregnancy recognition and conceptus implantation in domestic ruminants: roles of progesterone, interferons and endogenous retroviruses.

scientific article published on January 2007

Publisher Correction: Genomic epidemiology reveals multiple introductions of SARS-CoV-2 from mainland Europe into Scotland ⬇️

correction of a scholarly article

RNA interference targets arbovirus replication in Culicoides cells

scientific article

Reassortment between two serologically unrelated bluetongue virus strains is flexible and can involve any genome segment

scientific article

Receptor usage and fetal expression of ovine endogenous betaretroviruses: implications for coevolution of endogenous and exogenous retroviruses

scientific article

Relevance of Akt phosphorylation in cell transformation induced by Jaagsiekte sheep retrovirus

scientific article published in July 2003

Requirements for veterinary research and the recruitment of veterinary surgeons into research

scientific article published on 01 September 2007

Retrovirus-Induced Ovine Pulmonary Adenocarcinoma, an Animal Model for Lung Cancer ⬇️

scientific article published on November 7, 2001

Revealing the history of sheep domestication using retrovirus integrations

scientific article

Risk of adverse outcomes in patients with underlying respiratory conditions admitted to hospital with COVID-19: a national, multicentre prospective cohort study using the ISARIC WHO Clinical Characterisation Protocol UK

scientific article published in 2021

SARS-CoV-2-specific nasal IgA wanes 9 months after hospitalisation with COVID-19 and is not induced by subsequent vaccination

scientific article published in 2023

Schmallenberg virus pathogenesis, tropism and interaction with the innate immune system of the host.

scientific article

Sensitivity to BST-2 restriction correlates with Orthobunyavirus host range

scientific article

Sheep endogenous betaretroviruses (enJSRVs) and the hyaluronidase 2 (HYAL2) receptor in the ovine uterus and conceptus

scientific article

Sheep pulmonary adenomatosis: A unique model of retrovirus associated lung cancer ⬇️

scientific article published on December 1, 1997

Skeletal muscle hypoplasia represents the only significant lesion in peripheral organs of ruminants infected with Schmallenberg virus during gestation.

scientific article published on 26 June 2014

Spliced and prematurely polyadenylated Jaagsiekte sheep retrovirus-specific RNAs from infected or transfected cells

scientific article published on March 2002

Structure of the capsid amino-terminal domain from the betaretrovirus, Jaagsiekte sheep retrovirus

scientific article

TMPRSS2 promotes SARS-CoV-2 evasion from NCOA7-mediated restriction

scholarly article by Hataf Khan published in November 2021

TRIM69 Inhibits Vesicular Stomatitis Indiana Virus

scientific article published on 30 September 2019

Testicular degeneration and infertility following arbovirus infection

article

The P681H mutation in the Spike glycoprotein confers Type I interferon resistance in the SARS-CoV-2 alpha (B.1.1.7) variant

scientific article published on 10 November 2021

The Signal Peptide of a Recently Integrated Endogenous Sheep Betaretrovirus Envelope Plays a Major Role in Eluding Gag-Mediated Late Restriction ⬇️

scientific article published on May 18, 2011

The antiviral state has shaped the CpG composition of the vertebrate interferome to avoid self-targeting

scientific article published on 07 September 2021

The exogenous form of Jaagsiekte retrovirus is specifically associated with a contagious lung cancer of sheep

scientific article published on March 1996

The hyper-transmissible SARS-CoV-2 Omicron variant exhibits significant antigenic change, vaccine escape and a switch in cell entry mechanism

The long terminal repeat of Jaagsiekte sheep retrovirus is preferentially active in differentiated epithelial cells of the lungs

scientific article published on July 2000

The sheep tetherin paralog oBST2B blocks envelope glycoprotein incorporation into nascent retroviral virions

scientific article

The signal peptide of a simple retrovirus envelope functions as a posttranscriptional regulator of viral gene expression

scientific article

The transdominant endogenous retrovirus enJS56A1 associates with and blocks intracellular trafficking of Jaagsiekte sheep retrovirus Gag

scientific article published on 29 November 2006

The value of open-source clinical science in pandemic response: lessons from ISARIC

scientific article published in 2021

Transcriptome analysis reveals the host response to Schmallenberg virus in bovine cells and antagonistic effects of the NSs protein

scientific article published on 19 April 2015

Transformation and oncogenesis by jaagsiekte sheep retrovirus

scientific article

Transformation of rodent fibroblasts by the jaagsiekte sheep retrovirus envelope is receptor independent and does not require the surface domain.

scientific article

Transmission of Schmallenberg virus in a housed dairy herd in the UK.

scientific article

Transplacental transmission of field and rescued strains of BTV-2 and BTV-8 in experimentally infected sheep

scientific article published on 05 September 2013

Turnover Rate of NS3 Proteins Modulates Bluetongue Virus Replication Kinetics in a Host-Specific Manner

scientific article

Viral particles of endogenous betaretroviruses are released in the sheep uterus and infect the conceptus trophectoderm in a transspecies embryo transfer model.

scientific article

Virologists-Heroes need weapons.

scientific article published on 8 February 2018

Virus and host factors affecting the clinical outcome of bluetongue virus infection.

scientific article

Widespread Reassortment Shapes the Evolution and Epidemiology of Bluetongue Virus following European Invasion ⬇️

scientific article published on 7 August 2015

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