List of works - Patrick L. Sinn

Adherens junction protein nectin-4 is the epithelial receptor for measles virus

scientific article

Advances in cell and gene-based therapies for cystic fibrosis lung disease

scientific article

CFTR gene transfer with AAV improves early cystic fibrosis pig phenotypes

scientific article published on 08 September 2016

Cell-to-Cell Contact and Nectin-4 Govern Spread of Measles Virus from Primary Human Myeloid Cells to Primary Human Airway Epithelial Cells

scientific article published on 18 May 2016

Connections matter--how viruses use cell–cell adhesion components

scientific article

Correction for Singh et al., The Nectin-4/Afadin Protein Complex and Intercellular Membrane Pores Contribute to Rapid Spread of Measles Virus in Primary Human Airway Epithelia

scientific article published on 26 February 2016

Cystic Fibrosis Gene Therapy: Looking Back, Looking Forward

article

Different roles of the three loops forming the adhesive interface of nectin-4 in measles virus binding and cell entry, nectin-4 homodimerization, and heterodimerization with nectin-1

scientific article

Enhanced gene expression conferred by stepwise modification of a nonprimate lentiviral vector

scientific article published in December 2007

Extracellular Vesicle-Mediated siRNA Delivery, Protein Delivery, and CFTR Complementation in Well-Differentiated Human Airway Epithelial Cells

scientific article published on 26 March 2020

Ferret and pig models of cystic fibrosis: prospects and promise for gene therapy

scientific article

Gene therapy progress and prospects: development of improved lentiviral and retroviral vectors--design, biosafety, and production.

scientific article

Gene transfer to airway epithelia using feline immunodeficiency virus-based lentivirus vectors

scientific article published in January 2002

Gene transfer to respiratory epithelia with lentivirus pseudotyped with Jaagsiekte sheep retrovirus envelope glycoprotein

scientific article

Genetic therapies for cystic fibrosis lung disease

scientific article

Highly Regulated Cell Type-restricted Expression of Human Renin in Mice Containing 140- or 160-Kilobase Pair P1 Phage Artificial Chromosome Transgenes

scientific article published in Journal of Biological Chemistry

Human, Pig, and Mouse Interferon-Induced Transmembrane Proteins Partially Restrict Pseudotyped Lentiviral Vectors

scientific article published on 22 March 2016

Hybrid nonviral/viral vector systems for improved piggyBac DNA transposon in vivo delivery

scientific article

Identification of three human renin mRNA isoforms from alternative tissue-specific transcriptional initiation

scientific article published on 29 June 2000

In vivo gene transfer using a nonprimate lentiviral vector pseudotyped with Ross River Virus glycoproteins

scientific article

In vivo imaging of gene transfer to the respiratory tract

scientific article published on 21 December 2007

In vivo mouse studies with bioluminescence tomography

article

In vivo tomographic imaging based on bioluminescence

Inclusion of Jaagsiekte sheep retrovirus proviral elements markedly increases lentivirus vector pseudotyping efficiency

scientific article

Integrin α6β4 identifies human distal lung epithelial progenitor cells with potential as a cell-based therapy for cystic fibrosis lung disease

scientific article (publication date: 2013)

Interferon-γ Inhibits Ebola Virus Infection

scientific article

Intrapulmonary Versus Nasal Transduction of Murine Airways With GP64-pseudotyped Viral Vectors

scientific article published on 29 January 2013

Lentiviral Vectors Pseudotyped with Filoviral Glycoproteins

scientific article published on January 2017

Lentiviral vector gene transfer to porcine airways

scientific article

Lentiviral-mediated phenotypic correction of cystic fibrosis pigs

scientific article published on September 2016

Lentivirus vector can be readministered to nasal epithelia without blocking immune responses

scientific article published on 03 September 2008

Lentivirus vectors pseudotyped with filoviral envelope glycoproteins transduce airway epithelia from the apical surface independently of folate receptor alpha

scientific article

Long-term correction of hemophilia A mice following lentiviral mediated delivery of an optimized canine factor VIII gene.

scientific article published on 14 September 2017

Measles virus blind to its epithelial cell receptor remains virulent in rhesus monkeys but cannot cross the airway epithelium and is not shed

scientific article published on July 2008

Measles virus preferentially transduces the basolateral surface of well-differentiated human airway epithelia

scientific article

Novel GP64 envelope variants for improved delivery to human airway epithelial cells.

scientific article published on 7 September 2017

Persistent gene expression in mouse nasal epithelia following feline immunodeficiency virus-based vector gene transfer

scientific article

Progress and prospects: prospects of repeated pulmonary administration of viral vectors.

scientific article published on 30 July 2009

Rho GTPases modulate entry of Ebola virus and vesicular stomatitis virus pseudotyped vectors

scientific article published on 22 July 2009

T-cell immunoglobulin and mucin domain 1 (TIM-1) is a receptor for Zaire Ebolavirus and Lake Victoria Marburgvirus

scientific article

The Nectin-4/Afadin Protein Complex and Intercellular Membrane Pores Contribute to Rapid Spread of Measles Virus in Primary Human Airway Epithelia

scientific article (publication date: 29 April 2015)

The use of carboxymethylcellulose gel to increase non-viral gene transfer in mouse airways

scientific article

Transcriptional targeting in the airway using novel gene regulatory elements

scientific article

Tyrosine kinase receptor Axl enhances entry of Zaire ebolavirus without direct interactions with the viral glycoprotein

scientific article

Viscoelastic Gel Formulations Enhance Airway Epithelial Gene Transfer with Viral Vectors

article

piggyBac transposase tools for genome engineering

scientific article published on 30 May 2013

piggyBac-mediated phenotypic correction of factor VIII deficiency

scientific article

List of works by Patrick L. Sinn

Adherens junction protein nectin-4 is the epithelial receptor for measles virus

Advances in cell and gene-based therapies for cystic fibrosis lung disease

CFTR gene transfer with AAV improves early cystic fibrosis pig phenotypes

Cell-to-Cell Contact and Nectin-4 Govern Spread of Measles Virus from Primary Human Myeloid Cells to Primary Human Airway Epithelial Cells

Connections matter--how viruses use cell–cell adhesion components

Correction for Singh et al., The Nectin-4/Afadin Protein Complex and Intercellular Membrane Pores Contribute to Rapid Spread of Measles Virus in Primary Human Airway Epithelia

Cystic Fibrosis Gene Therapy: Looking Back, Looking Forward

Different roles of the three loops forming the adhesive interface of nectin-4 in measles virus binding and cell entry, nectin-4 homodimerization, and heterodimerization with nectin-1

Enhanced gene expression conferred by stepwise modification of a nonprimate lentiviral vector

Extracellular Vesicle-Mediated siRNA Delivery, Protein Delivery, and CFTR Complementation in Well-Differentiated Human Airway Epithelial Cells

Ferret and pig models of cystic fibrosis: prospects and promise for gene therapy

Gene therapy progress and prospects: development of improved lentiviral and retroviral vectors--design, biosafety, and production.

Gene transfer to airway epithelia using feline immunodeficiency virus-based lentivirus vectors

Gene transfer to respiratory epithelia with lentivirus pseudotyped with Jaagsiekte sheep retrovirus envelope glycoprotein

Genetic therapies for cystic fibrosis lung disease

Highly Regulated Cell Type-restricted Expression of Human Renin in Mice Containing 140- or 160-Kilobase Pair P1 Phage Artificial Chromosome Transgenes

Human, Pig, and Mouse Interferon-Induced Transmembrane Proteins Partially Restrict Pseudotyped Lentiviral Vectors

Hybrid nonviral/viral vector systems for improved piggyBac DNA transposon in vivo delivery

Identification of three human renin mRNA isoforms from alternative tissue-specific transcriptional initiation

In vivo gene transfer using a nonprimate lentiviral vector pseudotyped with Ross River Virus glycoproteins

In vivo imaging of gene transfer to the respiratory tract

In vivo mouse studies with bioluminescence tomography

In vivo tomographic imaging based on bioluminescence

Inclusion of Jaagsiekte sheep retrovirus proviral elements markedly increases lentivirus vector pseudotyping efficiency

Integrin α6β4 identifies human distal lung epithelial progenitor cells with potential as a cell-based therapy for cystic fibrosis lung disease

Interferon-γ Inhibits Ebola Virus Infection

Intrapulmonary Versus Nasal Transduction of Murine Airways With GP64-pseudotyped Viral Vectors

Lentiviral Vectors Pseudotyped with Filoviral Glycoproteins

Lentiviral vector gene transfer to porcine airways

Lentiviral-mediated phenotypic correction of cystic fibrosis pigs

Lentivirus vector can be readministered to nasal epithelia without blocking immune responses

Lentivirus vectors pseudotyped with filoviral envelope glycoproteins transduce airway epithelia from the apical surface independently of folate receptor alpha

Long-term correction of hemophilia A mice following lentiviral mediated delivery of an optimized canine factor VIII gene.

Measles virus blind to its epithelial cell receptor remains virulent in rhesus monkeys but cannot cross the airway epithelium and is not shed

Measles virus preferentially transduces the basolateral surface of well-differentiated human airway epithelia

Novel GP64 envelope variants for improved delivery to human airway epithelial cells.

Persistent gene expression in mouse nasal epithelia following feline immunodeficiency virus-based vector gene transfer

Progress and prospects: prospects of repeated pulmonary administration of viral vectors.

Rho GTPases modulate entry of Ebola virus and vesicular stomatitis virus pseudotyped vectors

T-cell immunoglobulin and mucin domain 1 (TIM-1) is a receptor for Zaire Ebolavirus and Lake Victoria Marburgvirus

The Nectin-4/Afadin Protein Complex and Intercellular Membrane Pores Contribute to Rapid Spread of Measles Virus in Primary Human Airway Epithelia

The use of carboxymethylcellulose gel to increase non-viral gene transfer in mouse airways

Transcriptional targeting in the airway using novel gene regulatory elements

Tyrosine kinase receptor Axl enhances entry of Zaire ebolavirus without direct interactions with the viral glycoprotein

Viscoelastic Gel Formulations Enhance Airway Epithelial Gene Transfer with Viral Vectors

piggyBac transposase tools for genome engineering

piggyBac-mediated phenotypic correction of factor VIII deficiency