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List of works by Marek Łos

9-Benzylidene-naphtho[2,3-b]thiophen-4-ones and benzylidene-9(10H)-anthracenones as novel tubulin interacting agents with high apoptosis-inducing activity.

scientific article published in August 2007

Activation and caspase-mediated inhibition of PARP: a molecular switch between fibroblast necrosis and apoptosis in death receptor signaling.

scientific article published on March 2002

Adenosine and deoxyadenosine induces apoptosis in oestrogen receptor-positive and -negative human breast cancer cells via the intrinsic pathway.

scientific article published on October 2005

Adult stem cells and their trans-differentiation potential--perspectives and therapeutic applications

scientific article

Airway mesenchymal cell death by mevalonate cascade inhibition: integration of autophagy, unfolded protein response and apoptosis focusing on Bcl2 family proteins

scientific article published on 15 March 2014

Akt-mediated phosphorylation of CDK2 regulates its dual role in cell cycle progression and apoptosis

scientific article

An Fc gamma receptor I (CD64)-negative subpopulation of human peripheral blood monocytes is resistant to killing by antigen-activated CD4-positive cytotoxic T cells

scientific article published on 01 September 1997

An efficient approach for the isolation, identification and evaluation of antimicrobial plant components on an analytical scale, demonstrated by the example of Radix imperatoriae.

scientific article published on 9 September 2010

An imidazole functionalized pentameric thiophene displays different staining patterns in normal and malignant cells

scientific article published on 7 October 2015

An overview of Brevinin superfamily: structure, function and clinical perspectives

scientific article published on January 2014

Anti-tumor chemotherapy utilizing peptide-based approaches--apoptotic pathways, kinases, and proteasome as targets.

scientific article

Anticancer drugs of tomorrow: apoptotic pathways as targets for drug design

scientific article

Apoptin, a tumor-selective killer.

scientific article published on 15 April 2009

Apoptin-induced cell death is modulated by Bcl-2 family members and is Apaf-1 dependent.

scientific article published in April 2006

Apoptins: selective anticancer agents.

scientific article

Apoptosis in liver diseases--detection and therapeutic applications.

scientific article

Autoimmunity and apoptosis--therapeutic implications

scientific article published on January 2007

Autophagy and apoptosis dysfunction in neurodegenerative disorders

scientific article

Autophagy, apoptosis, mitoptosis and necrosis: interdependence between those pathways and effects on cancer

scientific article published on 11 December 2012

Bacterial Infections and Osteoclastogenesis Regulators in Men and Women with Cholesteatoma.

scientific article

Brevinin-2R(1) semi-selectively kills cancer cells by a distinct mechanism, which involves the lysosomal-mitochondrial death pathway

scientific article

Cancer stem cell markers in common cancers - therapeutic implications

scientific article published on 03 September 2008

Cancer stem cells as targets for cancer therapy: selected cancers as examples.

scientific article

Cancer stem cells, cancer-initiating cells and methods for their detection

scientific article published on 11 March 2016

Cancer-selective therapy of the future: apoptin and its mechanism of action

scientific article

Cancer-specific toxicity of apoptin is independent of death receptors but involves the loss of mitochondrial membrane potential and the release of mitochondrial cell-death mediators by a Nur77-dependent pathway

scientific article published on October 2005

Caspases and cancer: mechanisms of inactivation and new treatment modalities

scientific article published in June 2004

Caspases--their role in apoptosis and other physiological processes as revealed by knock-out studies.

scientific article

Caspases: more than just killers?

scientific article

Catching chromatin relaxation in act by flow cytometry.

scientific article published on 15 July 2009

Cell survival, cell death and cell cycle pathways are interconnected: implications for cancer therapy

scientific article published on 14 February 2007

Cell type related differences in staining with pentameric thiophene derivatives.

scientific article

Chemosensitivity of solid tumor cellsin vitro is related to activation of the CD95 system

scientific article published on 01 March 1998

Clinical activities of the epidermal growth factor receptor family inhibitors in breast cancer

scientific article published on September 2007

Composite Nanofibers Containing Multiwall Carbon Nanotubes as Biodegradable Membranes in Reconstructive Medicine

scientific article published on 4 January 2019

Correction to: Human Gyrovirus-Apoptin Interferes with the Cell Cycle and Induces G2/M Arrest Prior to Apoptosis

scientific article published on 20 February 2020

Could drugs inhibiting the mevalonate pathway also target cancer stem cells?

scientific article published on 20 February 2016

Cytotoxic effects of intra and extracellular zinc chelation on human breast cancer cells

scientific article published on 10 November 2006

Different faces of hepatocellular carcinoma as a health threat in 21st century

scientific article published on 4 February 2013

Differential vital staining of normal fibroblasts and melanoma cells by an anionic conjugated polyelectrolyte.

scientific article

Direct Mechanical Stimulation of Stem Cells: A Beating Electromechanically Active Scaffold for Cardiac Tissue Engineering.

scientific article published on 29 April 2016

Ehrlichia chaffeensis uses its surface protein EtpE to bind GPI-anchored protein DNase X and trigger entry into mammalian cells

scientific article

Functional characterization of DNase X, a novel endonuclease expressed in muscle cells

scientific article published on 01 June 2000

Functional polymorphisms of FAS and FASL gene and risk of breast cancer - pilot study of 134 cases.

scientific article

Glucose starvation-mediated inhibition of salinomycin induced autophagy amplifies cancer cell specific cell death

scientific article published on April 2015

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

HMGA2 as a functional antagonist of PARP1 inhibitors in tumor cells

scientific article published on 28 November 2018

HSP70/IL-2 Treated NK Cells Effectively Cross the Blood Brain Barrier and Target Tumor Cells in a Rat Model of Induced Glioblastoma Multiforme (GBM)

scientific article published on 25 March 2020

Heterogeneous Mixture of Amniotic Cells is Likely a Better Source of Stem Cells than Adipose Tissue

scientific article published on 16 April 2019

Human Gyrovirus-Apoptin Interferes with the Cell Cycle and Induces G2/M Arrest Prior to Apoptosis.

scientific article published on 6 April 2017

Human induced pluripotent stem cell differentiation and direct transdifferentiation into corneal epithelial-like cells

scientific article published on 2 June 2016

Human-gyrovirus-Apoptin triggers mitochondrial death pathway--Nur77 is required for apoptosis triggering

scientific article published on September 2014

Hydrogen peroxide as a potent activator of T lymphocyte functions

scientific article published on 01 January 1995

Identification of poly(ADP-ribose)polymerase-1 and Ku70/Ku80 as transcriptional regulators of S100A9 gene expression

scientific article

Impact of Antibiotics on the Proliferation and Differentiation of Human Adipose-Derived Mesenchymal Stem Cells.

scientific article published on 24 November 2017

Important differences between topoisomerase-I and -II targeting agents

scientific article published on 14 August 2006

Inhibition of miR301 enhances Akt-mediated cell proliferation by accumulation of PTEN in nucleus and its effects on cell-cycle regulatory proteins.

scientific article published on 8 March 2016

Interaction with PI3-kinase contributes to the cytotoxic activity of apoptin

scientific article

Interconnections between apoptotic, autophagic and necrotic pathways: implications for cancer therapy development

scientific article published on 10 January 2013

LAPTM4B gene polymorphism augments the risk of cancer: Evidence from an updated meta-analysis

scientific article published on 25 September 2018

LMO1 polymorphisms and the risk of neuroblastoma: Assessment of meta-analysis of case-control studies

scientific article published on 12 December 2019

Mapping of apoptin-interaction with BCR-ABL1, and development of apoptin-based targeted therapy

scientific article published in August 2014

Mechanism of apoptosis induced by S100A8/A9 in colon cancer cell lines: the role of ROS and the effect of metal ions.

scientific article published in April 2004

Methods and biomarkers for the diagnosis and prognosis of cancer and other diseases: towards personalized medicine

scientific article published on August 2006

Mevalonate cascade regulation of airway mesenchymal cell autophagy and apoptosis: a dual role for p53

scientific article

Mitoptosis, a novel mitochondrial death mechanism leading predominantly to activation of autophagy

scientific article published on 20 August 2012

Modeling of molecular interaction between apoptin, BCR-Abl and CrkL--an alternative approach to conventional rational drug design

scientific article

Monitoring of autophagy is complicated--salinomycin as an example.

scientific article published on 23 December 2014

Monoclonal and bispecific antibodies as novel therapeutics

scientific article

Neuropathological and genomic characterization of glioblastoma-induced rat model: How similar is it to humans for targeted therapy?

scientific article published on 23 May 2019

New frontiers in the treatment of colorectal cancer: Autophagy and the unfolded protein response as promising targets

scientific article

New potential instrument to fight hepatocellular cancer by restoring p53 ⬇️

scientific article published on May 1, 2011

New, exciting developments in experimental therapies in the early 21st century

scientific article

Novel trends in application of stem cells in skin wound healing

scientific article published on 08 December 2018

Nuclear localized Akt enhances breast cancer stem-like cells through counter-regulation of p21(Waf1/Cip1) and p27(kip1).

scientific article

Obesity: pathophysiology and clinical management

scientific article published on January 2009

Peptide-based approaches to treat asthma, arthritis, other autoimmune diseases and pathologies of the central nervous system.

scientific article

Photodynamic N-TiO2 Nanoparticle Treatment Induces Controlled ROS-mediated Autophagy and Terminal Differentiation of Leukemia Cells

scientific article

Pre-administration of turmeric prevents methotrexate-induced liver toxicity and oxidative stress

scientific article published on 22 July 2015

Prolonged survival and expression of neural markers by bone marrow-derived stem cells transplanted into brain lesions

scientific article published in February 2009

Prospects and limitations of "Click-Chemistry"-based DNA labeling technique employing 5-ethynyl-2'deoxyuridine (EdU).

scientific article published on 30 September 2013

Quercetin as a Natural Therapeutic Candidate for the Treatment of Influenza Virus

scientific article published on 24 December 2020

Rapid extracellular release of cytochrome c is specific for apoptosis and marks cell death in vivo.

scientific article

Rational Design of a Conductive Collagen Heart Patch.

scientific article published on 21 March 2017

Redox events in HTLV-1 Tax-induced apoptotic T-cell death

scientific article

Redox signalling by transcription factors NF-kappa B and AP-1 in lymphocytes.

scientific article

Reprogramming and carcinogenesis--parallels and distinctions

scientific article published on January 2014

Rhodamine 110-Linked Amino Acids and Peptides as Substrates To Measure Caspase Activity upon Apoptosis Induction in Intact Cells†

scientific article published on 01 October 1999

Role of BNIP3 in TNF-induced cell death--TNF upregulates BNIP3 expression

scientific article published on 15 January 2009

Role of reactive oxygen intermediates in activation-induced CD95 (APO-1/Fas) ligand expression

scientific article published on 01 April 1998

Role of the salt bridge between glutamate 546 and arginine 907 in preservation of autoinhibited form of Apaf-1.

scientific article published on 12 August 2015

S100A8/9 induces cell death via a novel, RAGE-independent pathway that involves selective release of Smac/DIABLO and Omi/HtrA2.

scientific article published on 7 November 2007

S100A8/A9 at low concentration promotes tumor cell growth via RAGE ligation and MAP kinase-dependent pathway

scientific article published on 13 March 2008

S100A8/A9 induces autophagy and apoptosis via ROS-mediated cross-talk between mitochondria and lysosomes that involves BNIP3

scientific article

Salinomycin induces activation of autophagy, mitophagy and affects mitochondrial polarity: differences between primary and cancer cells

scientific article

Selected technologies to control genes and their products for experimental and clinical purposes.

scientific article published on May 2007

Serum cytochrome c indicates in vivo apoptosis and can serve as a prognostic marker during cancer therapy

scientific article published in August 2005

Spatiotemporal cytometry-simultaneous analysis of DNA replication and damage.

scientific article published on 4 October 2013

Statin-triggered cell death in primary human lung mesenchymal cells involves p53-PUMA and release of Smac and Omi but not cytochrome c.

scientific article published on 04 January 2010

Stroke, myocardial infarction, acute and chronic inflammatory diseases: caspases and other apoptotic molecules as targets for drug development

scientific article published in May 2004

Structure and properties of slow-resorbing nanofibers obtained by (co-axial) electrospinning as tissue scaffolds in regenerative medicine.

scientific article published on 18 December 2017

Switching Akt: from survival signaling to deadly response

scientific article

Targeting the EGFR pathway for cancer therapy

scientific article published on January 2006

The art of killing: double stroke with apoptin and survivin as a novel approach in cancer therapy

scientific article

The cytoplasmic domain of proEGF negatively regulates motility and elastinolytic activity in thyroid carcinoma cells.

scientific article published on October 2008

The emerging importance of DNA mapping and other comprehensive screening techniques, as tools to identify new drug targets and as a means of (cancer) therapy personalisation.

scientific article

The role of caspases in cryoinjury: caspase inhibition strongly improves the recovery of cryopreserved hematopoietic and other cells

scientific article published on 7 August 2002

The role of caspases in development, immunity, and apoptotic signal transduction: lessons from knockout mice.

scientific article

The role of ceramide in receptor- and stress-induced apoptosis studied in acidic ceramidase-deficient Farber disease cells.

scientific article published in October 2001

The tyrosine kinase lck is required for CD95-independent caspase-8 activation and apoptosis in response to ionizing radiation.

scientific article

Transdifferentiation and reprogramming: Overview of the processes, their similarities and differences

scientific article

Unscheduled Akt-triggered activation of cyclin-dependent kinase 2 as a key effector mechanism of apoptin's anticancer toxicity.

scientific article published on 22 December 2008

Viral modulation of cell death by inhibition of caspases.

scientific article

Virus-triggered autophagy in viral hepatitis - possible novel strategies for drug development

scientific article published on 13 October 2011

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