List of works - Alfonso Zambon

"Hexacarboxytrindanes": benzene rings with homotopic faces as scaffolds for the construction of D3 chiral architectures

scientific article published in December 2005

441 The discovery of novel, highly potent inhibitors of BRAF

article

A novel mechanism for the fluxional behaviour of [Pd(η2-tetramethylethylenetetracarboxylate)(2-methylthiomethylpyridine)]

A novel protocol for the one-pot borylation/Suzuki reaction provides easy access to hinge-binding groups for kinase inhibitors

scientific article published in December 2015

A novel, selective, and efficacious nanomolar pyridopyrazinone inhibitor of V600EBRAF.

scientific article

Abstract 3704: Novel panRAF inhibitors active in melanomas that are resistant to BRAF-selective, or BRAF-selective/MEK inhibitor combinations

article

BRAF as a therapeutic target: a patent review (2006 - 2012).

scientific article published on 07 January 2013

BRAF inhibitors based on an imidazo[4,5]pyridin-2-one scaffold and a meta substituted middle ring

scientific article

BRAF inhibitors induce metastasis in RAS mutant or inhibitor-resistant melanoma cells by reactivating MEK and ERK signaling

scientific article published on 25 March 2014

Characterization of compound 584, an Abl kinase inhibitor with lasting effects

scientific article

Chiral Polycyclic Ketones via Desymmetrization of Dihaloolefins

scientific article published on 03 May 2007

Correction to: Journal of Investigative Dermatology (2013) 133, 274–276; doi:10.1038/jid.2012.268; published online 16 August 2012

article

Corrections to Pyridoimidazolones as Novel Potent Inhibitors of v-Raf Murine Sarcoma Viral Oncogene Homologue B1 (BRAF)

article

Development and exploitation of CK2 inhibitors

scientific article published on June 2005

Development of novel, highly potent inhibitors of V-RAF murine sarcoma viral oncogene homologue B1 (BRAF): increasing cellular potency through optimization of a distal heteroaromatic group

scientific article

Discovery of Novel α-Carboline Inhibitors of the Anaplastic Lymphoma Kinase

scientific article published on 11 May 2022

Efficient access to 5-substituted thiazoles by a novel metallotropic rearrangement

Efficient cyclotrimerization of bicyclic vic-bromostannylalkenes promoted by copper(I) thiophen-2-carboxylate

scientific article published in November 2002

Gatekeeper mutations mediate resistance to BRAF-targeted therapies.

scientific article published on June 2010

Inhibiting EGF receptor or SRC family kinase signaling overcomes BRAF inhibitor resistance in melanoma

scientific article published on 14 December 2012

Internal motions in a fulleropyrrolidine tertiary amide with axial chirality

scientific article

Isolation and Characterization of All Eight Bisadducts of Fulleropyrrolidine Derivatives

scientific article published on 01 April 2001

Novel hinge binder improves activity and pharmacokinetic properties of BRAF inhibitors

scientific article published in August 2010

Novel potent BRAF inhibitors: toward 1 nM compounds through optimization of the central phenyl ring.

scientific article published in July 2009

Novel tricyclic pyrazole BRAF inhibitors with imidazole or furan central scaffolds.

scientific article

Paradox-breaking RAF inhibitors that also target SRC are effective in drug-resistant BRAF mutant melanoma

scientific article

Potent BRAF kinase inhibitors based on 2,4,5-trisubstituted imidazole with naphthyl and benzothiophene 4-substituents

scientific article published on 3 January 2013

Pyridoimidazolones as novel potent inhibitors of v-Raf murine sarcoma viral oncogene homologue B1 (BRAF).

scientific article published on April 2009

Qualitative and quantitative discrimination of fake and true alkene rotation processes in pd(η2-olefin) complexes. A new bimolecular mechanism

article by Vittorio Lucchini et al published June 2009 in Inorganica Chimica Acta

Small molecule inhibitors of BRAF in clinical trials

scientific article published on 03 December 2011

Study on the toxicity of phenolic and phenoxy herbicides using the submitochondrial particle assay.

scientific article published on 14 July 2005

Substituted aniline interaction with submitochondrial particles and quantitative structure-activity relationships

scientific article published in February 2002

Surface acidity modifications induced by thermal treatments and acid leaching on microcrystalline H-BEA zeolite. A FTIR, XRD and MAS-NMR study

Synthesis and evaluation of antiparasitic activities of new 4-[5-(4-phenoxyphenyl)-2H-pyrazol-3-yl]morpholine derivatives

scientific article published on 20 October 2007

Synthesis and evaluation of new chiral diols based on the dicyclopentadiene skeleton

Synthesis of the syn and anti isomer of 1,4,5,8,9,12-hexahydro-2,3,6,7,10,11-hexamethylidene-1,4:5,8:9,12-trimethano triphenylene and Diels–Alder reactivity of the syn isomer

Synthesis, structure-activity relationship and crystallographic studies of 3-substituted indolin-2-one RET inhibitors

scientific article

Tris-Annelated Benzenes Selectively Perfunctionalized on One Side Only: Hexachlorobenzotrinorbornadiene as a Versatile Scaffold for the Construction of Molecular Domes

List of works by Alfonso Zambon

"Hexacarboxytrindanes": benzene rings with homotopic faces as scaffolds for the construction of D3 chiral architectures

441 The discovery of novel, highly potent inhibitors of BRAF

A novel mechanism for the fluxional behaviour of [Pd(η2-tetramethylethylenetetracarboxylate)(2-methylthiomethylpyridine)]

A novel protocol for the one-pot borylation/Suzuki reaction provides easy access to hinge-binding groups for kinase inhibitors

A novel, selective, and efficacious nanomolar pyridopyrazinone inhibitor of V600EBRAF.

Abstract 3704: Novel panRAF inhibitors active in melanomas that are resistant to BRAF-selective, or BRAF-selective/MEK inhibitor combinations

BRAF as a therapeutic target: a patent review (2006 - 2012).

BRAF inhibitors based on an imidazo[4,5]pyridin-2-one scaffold and a meta substituted middle ring

BRAF inhibitors induce metastasis in RAS mutant or inhibitor-resistant melanoma cells by reactivating MEK and ERK signaling

Characterization of compound 584, an Abl kinase inhibitor with lasting effects

Chiral Polycyclic Ketones via Desymmetrization of Dihaloolefins

Correction to: Journal of Investigative Dermatology (2013) 133, 274–276; doi:10.1038/jid.2012.268; published online 16 August 2012

Corrections to Pyridoimidazolones as Novel Potent Inhibitors of v-Raf Murine Sarcoma Viral Oncogene Homologue B1 (BRAF)

Development and exploitation of CK2 inhibitors

Development of novel, highly potent inhibitors of V-RAF murine sarcoma viral oncogene homologue B1 (BRAF): increasing cellular potency through optimization of a distal heteroaromatic group

Discovery of Novel α-Carboline Inhibitors of the Anaplastic Lymphoma Kinase

Efficient access to 5-substituted thiazoles by a novel metallotropic rearrangement

Efficient cyclotrimerization of bicyclic vic-bromostannylalkenes promoted by copper(I) thiophen-2-carboxylate

Gatekeeper mutations mediate resistance to BRAF-targeted therapies.

Inhibiting EGF receptor or SRC family kinase signaling overcomes BRAF inhibitor resistance in melanoma

Internal motions in a fulleropyrrolidine tertiary amide with axial chirality

Isolation and Characterization of All Eight Bisadducts of Fulleropyrrolidine Derivatives

Novel hinge binder improves activity and pharmacokinetic properties of BRAF inhibitors

Novel potent BRAF inhibitors: toward 1 nM compounds through optimization of the central phenyl ring.

Novel tricyclic pyrazole BRAF inhibitors with imidazole or furan central scaffolds.

Paradox-breaking RAF inhibitors that also target SRC are effective in drug-resistant BRAF mutant melanoma

Potent BRAF kinase inhibitors based on 2,4,5-trisubstituted imidazole with naphthyl and benzothiophene 4-substituents

Pyridoimidazolones as novel potent inhibitors of v-Raf murine sarcoma viral oncogene homologue B1 (BRAF).

Qualitative and quantitative discrimination of fake and true alkene rotation processes in pd(η2-olefin) complexes. A new bimolecular mechanism

Small molecule inhibitors of BRAF in clinical trials

Study on the toxicity of phenolic and phenoxy herbicides using the submitochondrial particle assay.

Substituted aniline interaction with submitochondrial particles and quantitative structure-activity relationships

Surface acidity modifications induced by thermal treatments and acid leaching on microcrystalline H-BEA zeolite. A FTIR, XRD and MAS-NMR study

Synthesis and evaluation of antiparasitic activities of new 4-[5-(4-phenoxyphenyl)-2H-pyrazol-3-yl]morpholine derivatives

Synthesis and evaluation of new chiral diols based on the dicyclopentadiene skeleton

Synthesis of the syn and anti isomer of 1,4,5,8,9,12-hexahydro-2,3,6,7,10,11-hexamethylidene-1,4:5,8:9,12-trimethano triphenylene and Diels–Alder reactivity of the syn isomer

Synthesis, structure-activity relationship and crystallographic studies of 3-substituted indolin-2-one RET inhibitors

Tris-Annelated Benzenes Selectively Perfunctionalized on One Side Only: Hexachlorobenzotrinorbornadiene as a Versatile Scaffold for the Construction of Molecular Domes