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List of works by Young-Soo Hong

(Aryloxyacetylamino)benzoic acid analogues: A new class of hypoxia-inducible factor-1 inhibitors.

scientific article published on March 2007

6-alkylsalicylic acid analogues inhibit in vitro ATPase activity of heat shock protein 90 ⬇️

scientific article published on December 30, 2010

A new dimeric neolignan from Magnolia grandiflora L. seeds.

scientific article published on 6 September 2014

A peroxisome proliferator-activated receptor-gamma agonist and other constituents from Chromolaena odorata.

scientific article published on 25 February 2009

A pipecolic acid-rich branched cyclic depsipeptide ulleungamide C from a Streptomyces species induces G0/G1 cell cycle arrest in promyelocytic leukemia cells

scientific article published on 18 November 2020

Abietane diterpenes from Salvia miltiorrhiza inhibit the activation of hypoxia-inducible factor-1.

scientific article

Anti-angiogenic Activities of Novel Isocoumarins, AGI-7 and Sescandelin

scientific article published on 01 May 2001

Anti-tumor activity of WK88-1, a novel geldanamycin derivative, in gefitinib-resistant non-small cell lung cancers with Met amplification.

scientific article published on 25 September 2014

Antibacterial Cyclic Lipopeptide Enamidonins with an Enamide-Linked Acyl Chain from a Streptomyces Species

scientific article published on 19 October 2018

Anticancer effects of the Hsp90 inhibitor 17-demethoxy-reblastatin in human breast cancer MDA-MB-231 cells.

scientific article published on July 2014

Antifungal activity of salaceyin A against Colletotrichum orbiculare and Phytophthora capsici.

scientific article published in August 2007

Antioxidant benzoylated flavan-3-ol glycoside from Celastrus orbiculatus.

scientific article

Artificial biosynthesis of phenylpropanoic acids in a tyrosine overproducing Escherichia coli strain ⬇️

scientific article published on December 3, 2012

Artificial de novo biosynthesis of hydroxystyrene derivatives in a tyrosine overproducing Escherichia coli strain

scientific article published on 10 June 2015

Biosynthesis of Novel Glucosides Geldanamycin Analogs by Enzymatic Synthesis.

scientific article

Biosynthesis of methylated resveratrol analogs through the construction of an artificial biosynthetic pathway in E. coli.

scientific article

Biosynthesis of plant-specific phenylpropanoids by construction of an artificial biosynthetic pathway in Escherichia coli

scientific article

Biosynthesis of rubradirin as an ansamycin antibiotic from Streptomyces achromogenes var. rubradiris NRRL3061.

scientific article published on 14 December 2007

Biosynthesis of the heat-shock protein 90 inhibitor geldanamycin: new insight into the formation of the benzoquinone moiety

scientific article

Blockade of nuclear factor-kappaB signaling pathway and anti-inflammatory activity of cardamomin, a chalcone analog from Alpinia conchigera

scientific article

Boseongazepines A-C, pyrrolobenzodiazepine derivatives from a Streptomyces sp. 11A057.

scientific article

Catenulisporolides, Glycosylated Triene Macrolides from the Chemically Underexploited Actinomycete Catenulispora Species

scientific article published on 31 October 2018

Cephalochromin, a FabI-directed antibacterial of microbial origin.

scientific article published on 31 August 2007

Construction of an Artificial Biosynthetic Pathway for Zingerone Production in <i>Escherichia coli</i> Using Benzalacetone Synthase from <i>Piper methysticum</i>

scientific article published in 2021

Construction of artificial biosynthetic pathways for resveratrol glucoside derivatives

scientific article published in May 2014

Cytotoxic 6-alkylsalicylic acids from the endophytic Streptomyces laceyi. ⬇️

scientific article published on December 2006

De novo biosynthesis of pterostilbene in an Escherichia coli strain using a new resveratrol O-methyltransferase from Arabidopsis.

scientific article published on 15 February 2017

Enzymatic Biosynthesis of Novel Resveratrol Glucoside and Glycoside Derivatives.

scientific article

Enzymatic glycosylation of nonbenzoquinone geldanamycin analogs via Bacillus UDP-glycosyltransferase.

scientific article published on 24 August 2012

Enzymatic synthesis of novel isobavachalcone glucosides via a UDP-glycosyltransferase

scientific article

Geldanamycin inhibits TGF-beta signaling through induction of Hsp70.

scientific article

Genomics-Driven Discovery of Chlorinated Cyclic Hexapeptides Ulleungmycins A and B from a Streptomyces Species.

scientific article published on 30 October 2017

HFE polymorphisms influence the response to chemotherapeutic agents via induction of p16INK4A ⬇️

scientific article published on April 7, 2011

Haenamindole, an unusual diketopiperazine derivative from a marine-derived Penicillium sp. KCB12F005.

scientific article

Harzianums A and B produced by a fungal strain, Hypocrea sp. F000527, and their cytotoxicity against tumor cell lines.

scientific article

Highly oxygenated angucycline from Streptomyces sp. KCB15JA014

scientific article published on 10 July 2020

Hsp90 inhibition by WK88-1 potently suppresses the growth of gefitinib-resistant H1975 cells harboring the T790M mutation in EGFR.

scientific article published on 28 April 2014

Hypoxia-inducible factor-1 inhibitory benzofurans and chalcone-derived diels-alder adducts from Morus species.

scientific article

Identification of Three Positive Regulators in the Geldanamycin PKS Gene Cluster of Streptomyces hygroscopicus JCM4427

scientific article published on November 1, 2010

Identification of new geldanamycin derivatives from unexplored microbial culture extracts using a MS/MS library.

scientific article

In vivo antitumor efficacy and cardiotoxicity of novel anthracycline ID6105 (11-hydroxy-aclacinomycin X, Hyrubicin).

scientific article published on 21 September 2005

Inactivation of the carbamoyltransferase gene refines post-polyketide synthase modification steps in the biosynthesis of the antitumor agent geldanamycin.

scientific article published in September 2004

Inhibition of NF-κB activation through targeting IκB kinase by celastrol, a quinone methide triterpenoid

scientific article published on 18 September 2006

Inhibition of indoleamine 2,3-dioxygenase by thielavin derivatives from a soil fungus, Coniochaeta sp. 10F058.

scientific article

Isolation of new streptimidone derivatives, glutarimide antibiotics from Streptomyces sp. W3002 using LC-MS-guided screening

scientific article published on 18 December 2019

Lignans from Saururus chinensis inhibiting the transcription factor NF-kappaB.

scientific article published in October 2003

Mechanism of the pH-induced conformational change in the sensor domain of the DraK Histidine kinase via the E83, E105, and E107 residues

scientific article

Metabolic engineering for resveratrol derivative biosynthesis in Escherichia coli

scientific article

Mode of action of torilin in multidrug-resistant cancer cell lines.

scientific article published in May 1998

Mutasynthesis of geldanamycin by the disruption of a gene producing starter unit: generation of structural diversity at the benzoquinone ring

scientific article published in September 2007

New Anthracycline Metabolites Produced by the Aklavinone 11-Hydroxylase Gene in Streptomyces galilaeus ATCC 31133 ⬇️

article

New Cyclic Lipopeptides of the Iturin Class Produced by Saltern-Derived Bacillus sp. KCB14S006. ⬇️

scientific article published on 2 April 2016

New Geldanamycin Analogs from Streptomyces hygroscopicus

scientific article published on 01 November 2012

New non-quinone geldanamycin analogs from genetically engineered Streptomyces hygroscopicus. ⬇️

scientific article published on 30 March 2011

Non-Benzoquinone Geldanamycin Analog, WK-88-1, Induces Apoptosis in Human Breast Cancer Cell Lines

scientific article published on 01 April 2018

Non-benzoquinone geldanamycin analogs trigger various forms of death in human breast cancer cells

scientific article published on 22 September 2016

Optimization of Artificial Curcumin Biosynthesis in E. coli by Randomized 5'-UTR Sequences To Control the Multienzyme Pathway

scientific article published on 04 September 2018

Pharmacokinetics of 11-hydroxyaclacinomycin X (ID-6105), a novel anthracycline, after i.v. bolus multiple administration in rats.

scientific article published on April 2005

Phenolic constituents of Amorpha fruticosa that inhibit NF-kappaB activation and related gene expression.

scientific article

Polyketides and Anthranilic Acid Possessing 6-Deoxy-α-l-talopyranose from a Streptomyces Species.

scientific article

Pregnane Glycoside Multidrug-Resistance Modulators fromCynanchumwilfordii

scientific article published on 01 April 1999

Production of Bacterial Quorum Sensing Antagonists, Caffeoyl- and Feruloyl-HSL, by an Artificial Biosynthetic Pathway

scientific article published on 14 October 2017

Production of phenylacetyl-homoserine lactone analogs by artificial biosynthetic pathway in Escherichia coli

scientific article

Rational biosynthetic engineering for optimization of geldanamycin analogues

scientific article (publication date: 4 May 2009)

Sauchinone, a lignan from Saururus chinensis, suppresses iNOS expression through the inhibition of transactivation activity of RelA of NF-kappaB.

scientific article published in December 2003

Sesquiterpene Esters fromCelastrus orbiculatusand Their Structure−Activity Relationship on the Modulation of Multidrug Resistance

scientific article published on 01 May 1999

Stachybotrysin, an Osteoclast Differentiation Inhibitor from the Marine-Derived Fungus Stachybotrys sp. KCB13F013.

scientific article

Structures and biological activities of azaphilones produced by Penicillium sp. KCB11A109 from a ginseng field

scientific article published in February 2016

Suppression of RelA/p65 transactivation activity by a lignoid manassantin isolated from Saururus chinensis

scientific article published on 01 November 2003

Synthesis and anticancer activity of geldanamycin derivatives derived from biosynthetically generated metabolites

scientific article published on 30 November 2007

Synthesis of (aryloxyacetylamino)-isonicotinic/nicotinic acid analogues as potent hypoxia-inducible factor (HIF)-1alpha inhibitors.

scientific article

The first total synthesis of moracin O and moracin P, and establishment of the absolute configuration of moracin O.

scientific article published on 4 March 2009

Two new furanoditerpenes from Saururus chinenesis and their effects on the activation of peroxisome proliferator-activated receptor gamma.

scientific article published on April 2002

Ulleungamides A and B, Modified α,β-Dehydropipecolic Acid Containing Cyclic Depsipeptides from Streptomyces sp. KCB13F003.

scientific article published on 11 August 2015

Ulleungdin, a Lasso Peptide with Cancer Cell Migration Inhibitory Activity Discovered by the Genome Mining Approach

scientific article published on 25 September 2018

pH-dependent structural change of the extracellular sensor domain of the DraK histidine kinase from Streptomyces coelicolor.

scientific article published on 12 January 2013

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