Search filters

List of works by Michel Kranendonk

Alkylating potential of oxetanes.

scientific article published in July 2010

Altered human CYP3A4 activity caused by Antley-Bixler syndrome-related variants of NADPH-cytochrome P450 oxidoreductase measured in a robust in vitro system

scientific article published on 17 January 2012

Correction: The Hinge Segment of Human NADPH-Cytochrome P450 Reductase in Conformational Switching: The Critical Role of Ionic Strength.

scientific article

Cytochrome P450 expression system for high-throughput real-time detection of genotoxicity: Application to the study of human CYP1A2 variants

scientific article

DNA polymorphisms as modulators of genotoxicity and cancer.

scientific article

Editorial: Role of Protein-Protein Interactions in Metabolism: Genetics, Structure, Function

scientific article published on 27 November 2017

Escherichia coli BTC, a human cytochrome P450 competent tester strain with a high sensitivity towards alkylating agents: involvement of alkyltransferases in the repair of DNA damage induced by aromatic amines.

scientific article

Escherichia coli MTC, a NADPH cytochrome P450 reductase competent mutagenicity tester strain for the expression of human cytochrome P450: comparison of three types of expression systems

scientific article published on 01 February 1999

Escherichia coli MTC, a human NADPH P450 reductase competent mutagenicity tester strain for the expression of human cytochrome P450 isoforms 1A1, 1A2, 2A6, 3A4, or 3A5: catalytic activities and mutagenicity studies

scientific article published on 01 April 1999

Expression of human cytochrome P450 1A2 in Escherichia coli: a system for biotransformation and genotoxicity studies of chemical carcinogens.

scientific article published in May 1998

Functional characterization of eight human cytochrome P450 1A2 gene variants by recombinant protein expression.

scientific article published on 2 February 2010

Genotoxicity and endoreduplication inducing activity of the food flavouring eugenol.

scientific article published on 4 April 2006

Human cytochrome P450 expression in bacteria: Whole-cell high-throughput activity assay for CYP1A2, 2A6 and 3A4

scientific article published in 2018

Human cytochrome P450 oxidoreductase deficiency caused by the Y181D mutation: molecular consequences and rescue of defect.

scientific article

Human sulfotransferase 1A1-dependent mutagenicity of 12-hydroxy-nevirapine: the missing link?

scientific article published on 13 October 2014

Impairment of human CYP1A2-mediated xenobiotic metabolism by Antley-Bixler syndrome variants of cytochrome P450 oxidoreductase.

scientific article published on 20 April 2008

Instability of the Human Cytochrome P450 Reductase A287P Variant Is the Major Contributor to Its Antley-Bixler Syndrome-like Phenotype

scientific article published on 5 August 2016

Interaction Modes of Microsomal Cytochrome P450s with Its Reductase and the Role of Substrate Binding

scientific article published on 11 September 2020

MX100, a new Escherichia coli tester strain for use in genotoxicity studies.

scientific article

Non-specific binding of the fluorescent beta-adrenergic receptor probe alprenolol-NBD

scientific article published on 01 January 1985

Pleiotropy of Progesterone Receptor Membrane Component 1 in Modulation of Cytochrome P450 Activity

scientific article published in 2024

Probing the Role of the Hinge Segment of Cytochrome P450 Oxidoreductase in the Interaction with Cytochrome P450

scientific article published on 06 December 2018

Prototype Systems Containing Human Cytochrome P450 for High-Throughput Real-Time Detection of DNA Damage by Compounds That Form DNA-Reactive Metabolites

scientific article

Simple and sensitive antimalarial drug screening in vitro and in vivo using transgenic luciferase expressing Plasmodium berghei parasites

scientific article published on 12 June 2008

The Hinge Segment of Human NADPH-Cytochrome P450 Reductase in Conformational Switching: The Critical Role of Ionic Strength

scientific article published on 30 October 2017

The stimulatory role of human cytochrome b5 in the bioactivation activities of human CYP1A2, 2A6 and 2E1: a new cell expression system to study cytochrome P450 mediated biotransformation.

scientific article

The stimulatory role of human cytochrome b5 in the bioactivation activities of human CYP1A2, 2A6 and 2E1: a new cell expression system to study cytochrome P450-mediated biotransformation (a corrigendum report on Duarte et al. (2005) Mutagenesis 20,

scientific article published on 08 December 2006

Toxicological Assessment of Cellulose Nanomaterials: Oral Exposure

scientific article published in 2022