Search filters

List of works by Constantine S. Tam

'Leukaemic' presentation of metastatic Merkel cell carcinoma

scientific article published on 01 May 2005

A case of systemic anaplastic lymphoma kinase-negative anaplastic large cell lymphoma associated with hypereosinophilia, granulomatous myositis and vasculitis.

scientific article

A multicentre retrospective comparison of central nervous system prophylaxis strategies among patients with high-risk diffuse large B-cell lymphoma

scientific article published on 29 July 2014

A new model for predicting infectious complications during fludarabine-based combination chemotherapy among patients with indolent lymphoid malignancies.

scientific article published in November 2004

A new prognostic score for CLL.

scientific article published in July 2014

A novel way to consolidate incomplete responses in chronic lymphocytic leukemia/small lymphocytic lymphoma

scientific article published on 15 October 2015

ABVD versus BEACOPP for Hodgkin's Lymphoma ⬇️

scientific article published on October 20, 2011

All is not lost--the improving outcome of patients with chronic lymphocytic leukaemia failing frontline therapy with fludarabine, cyclophosphamide and rituximab

scientific article published on 28 June 2013

Allogeneic immunity and anti-CD20 therapy: a potent combination in the treatment of a patient with Richter transformation of chronic lymphocytic leukemia ⬇️

scientific article published on June 26, 2012

Ante-mortem diagnosis of localized invasive esophageal aspergillosis in a patient with acute myeloid leukemia.

scientific article

Association between early peak temperature and mortality in neutropenic sepsis

scientific article published on 18 December 2014

Atrial fibrillation in CLL patients treated with ibrutinib. An international retrospective study.

scientific article published on 9 September 2016

Autologous and allogeneic stem cell transplantation: rising therapeutic promise for mantle cell lymphoma

scientific article published on August 2009

Autologous stem cell transplantation for untreated transformed indolent B-cell lymphoma in first remission: an international, multi-centre propensity-score-matched study

scientific article published on 16 October 2020

B-CLL cells acquire APC- and CTL-like phenotypic characteristics after stimulation with CpG ODN and IL-21

scientific article

CD38 expression in CLL: a dynamic marker of prognosis

scientific article published on 07 May 2013

Cardiac side effects of bruton tyrosine kinase (BTK) inhibitors.

scientific article

Central nervous system immune reconstitution inflammatory syndrome after ibrutinib therapy for Richter transformation.

scientific article

Characteristics and outcome of patients with relapsed/refractory Hodgkin lymphoma following front-line escalated BEACOPP-based chemotherapy: a report from the Australasian Lymphoma Alliance

scientific article published on 28 August 2020

Charting the path to the cure of chronic lymphocytic leukemia: consolidation strategies currently lead the way.

scientific article published in October 2009

Chemoimmunotherapy may overcome the adverse prognostic significance of 11q deletion in previously untreated patients with chronic lymphocytic leukemia

scientific article

Chemotherapy Versus Autologous Stem-Cell Transplantation for the Treatment of Transformed Follicular Lymphoma in the Rituximab Era ⬇️

scientific article published on August 5, 2013

Choosing and sequencing novel drugs in CLL: dealing with an embarrassment of riches?

scientific article

Chronic lymphocytic leukaemia CD20 expression is dependent on the genetic subtype: a study of quantitative flow cytometry and fluorescent in-situ hybridization in 510 patients

scientific article

Chronic lymphocytic leukemia presenting as an intracranial epidural mass in a patient with myeloproliferative neoplasm associated with JAK2 V617F mutation

scientific article published on 19 November 2012

Chronic lymphoproliferative disorders and secondary cancers in the era of purine analogues and beyond

scientific article published on 22 November 2020

Circulating tumour DNA reflects treatment response and clonal evolution in chronic lymphocytic leukaemia.

scientific article published on 17 March 2017

Clinicopathological features and outcomes of progression of CLL on the BCL2 inhibitor venetoclax.

scientific article

Comment on Lipsky et al.: Incidence and Risk Factors of Bleeding-Related Adverse Events in Patients with Chronic Lymphocytic Leukemia Treated with Ibrutinib

scientific article published on March 2016

Consensus guidelines for antifungal prophylaxis in haematological malignancy and haemopoietic stem cell transplantation, 2014.

scientific article

Consensus guidelines for the diagnosis and management of patients with classic hairy cell leukemia

scientific article

Cytokine-driven loss of plasmacytoid dendritic cell function in chronic lymphocytic leukemia

scientific article

Dancing partners at the ball: Rational selection of next generation anti-CD20 antibodies for combination therapy of chronic lymphocytic leukemia in the novel agents era.

scientific article

De novo deletion 17p13.1 chronic lymphocytic leukemia shows significant clinical heterogeneity: the M. D. Anderson and Mayo Clinic experience

scientific article published on 04 May 2009

Defining the appropriate starting dose of lenalidomide in chronic lymphocytic leukemia: remember the old fable of the hare and the tortoise

scientific article published on 17 February 2016

Diagnostic techniques and therapeutic challenges in patients with TP53 dysfunctional chronic lymphocytic leukemia.

scientific article published on 31 May 2012

Disseminated visceral varicella zoster virus presenting with the constellation of colonic pseudo-obstruction, acalculous cholecystitis and syndrome of inappropriate ADH secretion

scientific article published in February 2016

Dose-reduced fludarabine, cyclophosphamide and rituximab is well tolerated in older patients with chronic lymphocytic leukemia and has preserved therapeutic efficacy.

scientific article published on 13 October 2015

Dynamic model for predicting death within 12 months in patients with primary or post-polycythemia vera/essential thrombocythemia myelofibrosis

scientific article published on 28 September 2009

Effective treatment of Waldenström macroglobulinemia associated pure red cell aplasia with standard antilymphomatous chemotherapy.

scientific article published on 28 August 2013

Efficacy and safety of ruxolitinib in the treatment of patients with myelofibrosis.

scientific article published on January 2015

Evaluation of 230 patients with relapsed/refractory deletion 17p chronic lymphocytic leukaemia treated with ibrutinib from 3 clinical trials

scientific article published on 05 June 2018

Excellent outcomes in older patients with primary CNS lymphoma treated with R-MPV/cytarabine without whole brain radiotherapy or autologous stem cell transplantation therapy

scientific article published on 27 September 2020

Extended follow-up and impact of high-risk prognostic factors from the phase 3 RESONATE study in patients with previously treated CLL/SLL. ⬇️

scientific article

Externally validated predictive clinical model for untreated del(17p13.1) chronic lymphocytic leukemia patients

scientific article published on 22 July 2015

FDG PET in follicular lymphoma: more than a staging test?

scientific article published on 16 January 2017

Factors predicting the identification of new organisms in follow-up blood cultures drawn during episodes of neutropenic sepsis

scientific article published on 23 June 2017

Failure to achieve a major cytogenetic response by 12 months defines inadequate response in patients receiving nilotinib or dasatinib as second or subsequent line therapy for chronic myeloid leukemia

scientific article published on 20 May 2008

Fludarabine and cyclophosphamide using an attenuated dose schedule is a highly effective regimen for patients with indolent lymphoid malignancies.

scientific article published on May 2004

Fludarabine based combinations are highly effective as first-line or salvage treatment in patients with Waldenström macroglobulinemia.

scientific article published on 12 October 2010

Fludarabine, cyclophosphamide, and rituximab chemotherapy followed by rituximab maintenance in follicular lymphoma: high efficacy may come at a cost?

scientific article published on 01 May 2011

Fludarabine, cyclophosphamide, and rituximab for the treatment of patients with chronic lymphocytic leukemia or indolent non-Hodgkin lymphoma.

scientific article published on June 2006

Fludarabine, cyclophosphamide, and rituximab treatment achieves long-term disease-free survival in IGHV-mutated chronic lymphocytic leukemia

scientific article published on 22 October 2015

Global measures of peripheral blood-derived DNA methylation as a risk factor in the development of mature B-cell neoplasms

scientific article published on 18 December 2015

Hepatitis-B reactivation and rituximab-containing chemotherapy: an increasingly complex clinical challenge

scientific article published on 01 September 2010

High incidence of Pneumocystis jirovecii pneumonia in patients receiving biweekly rituximab and cyclophosphamide, adriamycin, vincristine, and prednisone

scientific article published in May 2010

High prevalence of antibiotic allergies in cladribine-treated patients with hairy cell leukemia - lessons for immunopathogenesis and prescribing

scientific article published on 01 July 2019

High-dose therapy and autologous stem cell transplantation may only be applicable to selected patients with secondary CNS diffuse large B-cell lymphoma.

scientific article published on 29 July 2016

High-risk diffuse large B-cell lymphoma: can we do better than rituximab, cyclophosphamide, doxorubicin, vincristine and prednisone?

scientific article published on 21 May 2013

How applicable is fludarabine, cyclophosphamide and rituximab to the elderly?

scientific article

Ibrutinib as Initial Therapy for Patients with Chronic Lymphocytic Leukemia ⬇️

scientific article

Ibrutinib for patients with rituximab-refractory Waldenström's macroglobulinaemia (iNNOVATE): an open-label substudy of an international, multicentre, phase 3 trial.

scientific article

Ibrutinib for the treatment of Bing-Neel syndrome: a multicenter study

scientific article published on 06 December 2018

Ibrutinib inhibits collagen-mediated but not ADP-mediated platelet aggregation.

scientific article published on 20 August 2014

Ibrutinib may impair serological responses to influenza vaccination

scientific article published on 28 June 2017

Ibrutinib monotherapy as effective treatment of central nervous system involvement by chronic lymphocytic leukaemia

scientific article published on 25 February 2016

Ibrutinib plus Venetoclax for the Treatment of Mantle-Cell Lymphoma

scientific article published in March 2018

Ibrutinib treatment affects collagen and von Willebrand factor-dependent platelet functions.

scientific article published on 10 October 2014

Ibrutinib versus ofatumumab in previously treated chronic lymphoid leukemia

scientific article

Immune impacts of Bruton tyrosine kinase inhibitors in chronic lymphocytic leukemia patients: are we closer to a holy grail?

scientific article published on 08 September 2020

Immunohistochemical detection of ZAP70 in chronic lymphocytic leukemia predicts immunoglobulin heavy chain gene mutation status and time to progression

scientific article

In defence of the use of modern chemotherapy regimens for the treatment of patients with chronic lymphocytic leukaemia.

scientific article published in December 2009

Infections in patients with chronic lymphocytic leukaemia: Mitigating risk in the era of targeted therapies.

scientific article

Investigational Janus kinase inhibitors.

scientific article

Lack of durable disease control with chemotherapy for mycosis fungoides and Sézary syndrome: a comparative study of systemic therapy

scientific article published on 21 October 2014

Late-onset Pneumocystis jirovecii pneumonia post-fludarabine, cyclophosphamide and rituximab: implications for prophylaxis

scientific article published on 15 June 2013

Leukaemic subtype of marginal zone lymphoma: a presentation of three cases and literature review.

scientific article published on April 2004

Limited clinical benefit for surveillance PET-CT scanning in patients with histologically transformed lymphoma in complete metabolic remission following primary therapy

scientific article published on 05 March 2014

Long-term outcome of patients with chronic myeloid leukemia treated with second-generation tyrosine kinase inhibitors after imatinib failure is predicted by the in vitro sensitivity of BCR-ABL kinase domain mutations

scientific article

Long-term results of first salvage treatment in CLL patients treated initially with FCR (fludarabine, cyclophosphamide, rituximab)

scientific article

Long-term results of the fludarabine, cyclophosphamide, and rituximab regimen as initial therapy of chronic lymphocytic leukemia

scientific article published on 14 April 2008

Maintenance therapy in CLL: resolving the controversy

scientific article published on 16 June 2016

Management of high risk chronic lymphocytic leukaemia (CLL) patients in Australia

scientific article published in December 2017

Management of patients with previously untreated chronic lymphocytic leukaemia with obinutuzumab and chlorambucil

scientific article

Mature results of the M. D. Anderson Cancer Center risk-adapted transplantation strategy in mantle cell lymphoma

scientific article

Microvesicles in chronic lymphocytic leukemia: ready for prime time in the clinic?

scientific article published in June 2017

Modifying the immune system to treat chronic lymphocytic leukemia

scientific article published on 15 November 2011

Myelosuppression after frontline fludarabine, cyclophosphamide, and rituximab in patients with chronic lymphocytic leukemia: analysis of persistent and new-onset cytopenia

scientific article

New angles of attack in the fight against chronic lymphocytic leukemia: the advent of novel non-chemotherapeutic agents.

scientific article published on September 2010

Novel agents versus chemotherapy as frontline treatment of CLL.

scientific article

Out of sight, out of mind: an audit of inferior vena cava filter insertion and clinical follow up in an Australian institution and literature review.

scientific article published on April 2013

Peripheral T cell and natural killer (NK) T cell lymphomas: a clinicopathological study from a single Australian centre.

scientific article published on 20 June 2012

Phase 1 study of the selective BTK inhibitor zanubrutinib in B-cell malignancies and safety and efficacy evaluation in CLL

scientific article published on 24 July 2019

Phase I evaluation of XL019, an oral, potent, and selective JAK2 inhibitor

scientific article published on 11 December 2013

Phase I trial of nelarabine in indolent leukemias

scientific article

Plasmablastic Richter transformation as a resistance mechanism for chronic lymphocytic leukaemia treated with BCR signalling inhibitors

scientific article published on 15 May 2016

Practical management of myelofibrosis with ruxolitinib.

scientific article

Practical recommendations for the choice of anticoagulants in the management of patients with atrial fibrillation on ibrutinib.

scientific article

Predicting survival in chronic lymphocytic leukemia ⬇️

scientific article published on March 1, 2012

Prognostic interaction between thrombocytosis and JAK2 V617F mutation in the WHO subcategories of myelodysplastic/myeloproliferative disease-unclassifiable and refractory anemia with ringed sideroblasts and marked thrombocytosis

scientific article published on 06 December 2007

Progress in BCL2 inhibition for patients with chronic lymphocytic leukemia

scientific article published on 6 February 2016

Protein kinase C isoform expression in chronic lymphocytic leukemia: a potential target for therapy? ⬇️

scientific article published on April 19, 2013

Rapid resolution of Mycobacterium marinum chronic skin infection during lenalidomide therapy for chronic lymphocytic leukemia

scientific article published in April 2008

Recommendations for the diagnosis and initial evaluation of patients with Waldenström Macroglobulinaemia: A Task Force from the 8th International Workshop on Waldenström Macroglobulinaemia

scientific article published on 05 July 2016

Relevance of the immunoglobulin VH somatic mutation status in patients with chronic lymphocytic leukemia treated with fludarabine, cyclophosphamide, and rituximab (FCR) or related chemoimmunotherapy regimens

scientific article published on 02 December 2008

Rituximab is associated with improved survival for aggressive B cell CNS lymphoma ⬇️

scientific article published on March 15, 2013

Selection of rituximab dosage in chronic lymphocytic leukemia: where is the evidence? ⬇️

scientific article published on September 28, 2012

Severe hemolysis and transfusion reactions after treatment with BGB-3111 and PD-1 antibody for Waldenström Macroglobulinemia.

scientific article published on 8 February 2018

Severe treatment-resistant autoimmune haemolytic anaemia following ipilimumab in a patient with metastatic melanoma and CLL

scientific article published on 21 November 2020

Splenectomy in patients with myeloproliferative neoplasms: efficacy, complications and impact on survival and transformation

scientific article

Src family kinases and their role in hematological malignancies

scientific article

Survey of antifungal prophylaxis and fungal diagnostic tests employed in malignant haematology and haemopoietic stem cell transplantation (HSCT) in Australia and New Zealand

scientific article

TIDEL-II: first-line use of imatinib in CML with early switch to nilotinib for failure to achieve time-dependent molecular targets

scientific article published on 17 December 2014

The BAFF receptor TACI controls IL-10 production by regulatory B cells and CLL B cells

scientific article

The BCL2 selective inhibitor venetoclax induces rapid onset apoptosis of CLL cells in patients via a TP53-independent mechanism.

scientific article published on 11 April 2016

The absolute percent deviation of IGHV mutation rather than a 98% cut-off predicts survival of chronic lymphocytic leukaemia patients treated with fludarabine, cyclophosphamide and rituximab

scientific article published on 21 November 2017

The efficacy and stem cell toxicity of cladribine and rituximab in the treatment of patients with chronic lymphocytic leukemia: are all purine analogs created equal?

scientific article published in April 2010

The infectious consequences of rituximab addition to fludarabine-containing regimens

scientific article published in April 2006

The influence of increasing age on the deliverability and toxicity of fludarabine-based combination chemotherapy regimens in patients with indolent lymphoproliferative disorders.

scientific article

The natural history and treatment outcome of blast phase BCR-ABL- myeloproliferative neoplasms

scientific article published on 19 June 2008

The natural history of fludarabine-refractory chronic lymphocytic leukemia patients who fail alemtuzumab or have bulky lymphadenopathy

scientific article published in October 2007

The oral iron chelator deferasirox inhibits NF-κB mediated gene expression without impacting on proximal activation: implications for myelodysplasia and aplastic anaemia.

scientific article published on October 2014

The positive effect of deferasirox on erythropoiesis in a patient with a dual diagnosis of myelofibrosis and diffuse large B-cell lymphoma

scientific article published on 23 March 2017

The rare entity of chronic lymphocytic leukemia in Chinese patients: is it the same disease as in Western patients?

scientific article published on 01 October 2008

The role of cytogenetic abnormalities as a prognostic marker in primary myelofibrosis: applicability at the time of diagnosis and later during disease course

scientific article published on 8 January 2009

The utility and limitations of (18)F-fluorodeoxyglucose positron emission tomography with computed tomography in patients with primary mediastinal B-cell lymphoma: single institution experience and literature review.

scientific article published on 16 June 2014

Therapy-related myelodysplastic syndrome and acute myeloid leukemia following fludarabine combination chemotherapy.

scientific article published on 21 October 2010

Thrombosis of the corpora cavernosa complicating lenalidomide therapy of myelofibrosis

scientific article published on 17 September 2007

Treatment of patients with Waldenström macroglobulinaemia: clinical practice guidelines from the Myeloma Foundation of Australia Medical and Scientific Advisory Group.

scientific article published in January 2017

Tumor Lysis Syndrome in Chronic Lymphocytic Leukemia with Novel Targeted Agents.

scientific article published on 29 August 2017

Tumour debulking and reduction in predicted risk of tumour lysis syndrome with single-agent ibrutinib in patients with chronic lymphocytic leukaemia

scientific article published on 10 February 2019

Use of anticoagulants and antiplatelet in patients with chronic lymphocytic leukaemia treated with single-agent ibrutinib.

scientific article published on 10 April 2017

Use of empiric antimicrobial therapy in neutropenic fever. Australian Consensus Guidelines 2011 Steering Committee.

scientific article published on January 2011

Venetoclax plus rituximab in relapsed or refractory chronic lymphocytic leukaemia: a phase 1b study

scientific article

Venous thromboembolism prevention in patients undergoing colorectal surgery for cancer ⬇️

scientific article published on June 19, 2013

Zanubrutinib for the treatment of Waldenström Macroglobulinemia

scientific article published on 09 December 2020

p53 expression by immunohistochemistry is an important determinant of survival in patients with chronic lymphocytic leukemia receiving frontline chemo-immunotherapy

scientific article published on October 2009

Paulina is supported by:

About Paulina

Help