List of works - Giuseppe Penna

1,25-Dihydroxyvitamin D3 selectively modulates tolerogenic properties in myeloid but not plasmacytoid dendritic cells

scientific article

A gut-vascular barrier controls the systemic dissemination of bacteria.

scientific article published in November 2015

A vitamin D analog down-regulates proinflammatory chemokine production by pancreatic islets inhibiting T cell recruitment and type 1 diabetes development.

scientific article

BALB/c and C57BL/6 Mice Differ in Polyreactive IgA Abundance, which Impacts the Generation of Antigen-Specific IgA and Microbiota Diversity

scientific article published on 5 September 2015

Calcitriol derivatives with two different side chains at C-20 III. An epimeric pair of the gemini family with unprecedented antiproliferative effects on tumor cells and renin mRNA expression inhibition.

scientific article published on 24 January 2007

Chronic inflammation in the pathogenesis of benign prostatic hyperplasia.

scientific article published on 08 June 2009

Coagulation induced by C3aR-dependent NETosis drives protumorigenic neutrophils during small intestinal tumorigenesis.

scientific article

Control of autoimmune diseases by the vitamin D endocrine system

scientific article published on July 2008

Cutting edge: differential chemokine production by myeloid and plasmacytoid dendritic cells

scientific article published on 01 December 2002

Cutting edge: selective usage of chemokine receptors by plasmacytoid dendritic cells

scientific article published on 01 August 2001

Delivery to the central nervous system of a nonreplicative herpes simplex type 1 vector engineered with the interleukin 4 gene protects rhesus monkeys from hyperacute autoimmune encephalomyelitis

scientific article published on May 2001

Dendritic cell tolerogenicity: a key mechanism in immunomodulation by vitamin D receptor agonists.

scientific article published in May 2009

Dendritic cells as key targets for immunomodulation by Vitamin D receptor ligands

scientific article

Deviation of pancreas-infiltrating cells to Th2 by interleukin-12 antagonist administration inhibits autoimmune diabetes

scientific article published on 01 September 1997

Dichotomy of short and long thymic stromal lymphopoietin isoforms in inflammatory disorders of the bowel and skin

scientific article

Differential migration behavior and chemokine production by myeloid and plasmacytoid dendritic cells.

scientific article

Early Th1 response in unprimed nonobese diabetic mice to the tyrosine phosphatase-like insulinoma-associated protein 2, an autoantigen in type 1 diabetes

scientific article published on 01 December 2000

Efficacy of a potent and safe vitamin D receptor agonist for the treatment of inflammatory bowel disease

scientific article published on 27 March 2010

Expression of the inhibitory receptor ILT3 on dendritic cells is dispensable for induction of CD4+Foxp3+ regulatory T cells by 1,25-dihydroxyvitamin D3.

scientific article

Farnesoid X receptor activation inhibits inflammation and preserves the intestinal barrier in inflammatory bowel disease

scientific journal article

Functional maturation of adult mouse resting microglia into an APC is promoted by granulocyte-macrophage colony-stimulating factor and interaction with Th1 cells

scientific article published on 01 February 2000

Genomic diversity and immunomodulatory activity of Lactobacillus plantarum isolated from dairy products

scientific article published on 30 May 2017

Human benign prostatic hyperplasia stromal cells as inducers and targets of chronic immuno-mediated inflammation.

scientific article published on April 2009

Human immunodeficiency virus type 1 gp120 and other activation stimuli are highly effective in triggering alpha interferon and CC chemokine production in circulating plasmacytoid but not myeloid dendritic cells.

scientific article

IL-12 production by central nervous system microglia is inhibited by astrocytes ⬇️

scientific article published on August 15, 1997

Induction of macrophage-derived chemokine/CCL22 expression in experimental autoimmune encephalomyelitis and cultured microglia: implications for disease regulation

scientific article published on 01 September 2002

Induction of transplantation tolerance by 1,25-dihydroxyvitamin D(3).

scientific article

Inhibition of costimulatory pathways for T-cell activation by 1,25-dihydroxyvitamin D(3).

scientific article published in May 2001

Inhibition of prostate growth and inflammation by the vitamin D receptor agonist BXL-628 (elocalcitol)

scientific article published in March 2007

Lactobacillus paracasei CBA L74 metabolic products and fermented milk for infant formula have anti-inflammatory activity on dendritic cells in vitro and protective effects against colitis and an enteric pathogen in vivo

scientific article

Manipulating dendritic cells to induce regulatory T cells.

scientific article

Oral tolerance can be established via gap junction transfer of fed antigens from CX3CR1⁺ macrophages to CD103⁺ dendritic cells

scientific article published on 23 January 2014

Pharmacological induction of tolerogenic dendritic cells and regulatory T cells.

scientific article published on April 2004

Polymorphisms in the Il12b gene affect structure and expression of IL-12 in NOD and other autoimmune-prone mouse strains.

scientific article

Probiotic and postbiotic activity in health and disease: comparison on a novel polarised ex-vivo organ culture model

scientific article

Seminal plasma cytokines and chemokines in prostate inflammation: interleukin 8 as a predictive biomarker in chronic prostatitis/chronic pelvic pain syndrome and benign prostatic hyperplasia

scientific article

Spontaneous and prostatic steroid binding protein peptide-induced autoimmune prostatitis in the nonobese diabetic mouse

scientific article published on 01 August 2007

Synthesis and anti-inflammatory properties of 1alpha,25-dihydroxy-16-ene-20-cyclopropyl-24-oxo-vitamin D3, a hypocalcemic, stable metabolite of 1alpha,25-dihydroxy-16-ene-20-cyclopropyl-vitamin D3.

scientific article published on April 2009

The EGFR-specific antibody cetuximab combined with chemotherapy triggers immunogenic cell death.

scientific article published on 2 May 2016

The vitamin D receptor agonist elocalcitol inhibits IL-8-dependent benign prostatic hyperplasia stromal cell proliferation and inflammatory response by targeting the RhoA/Rho kinase and NF-kappaB pathways

scientific article

Thiol antioxidants inhibit the formation of the interleukin-12 heterodimer: a novel mechanism for the inhibition of IL-12 production.

scientific article

Tolerogenic dendritic cells induced by vitamin D receptor ligands enhance regulatory T cells inhibiting allograft rejection and autoimmune diseases.

scientific article

Treatment of experimental autoimmune prostatitis in nonobese diabetic mice by the vitamin D receptor agonist elocalcitol

scientific article

Vitamin D receptor agonists as anti-inflammatory agents

scientific article published on 01 July 2007

Vitamin D receptor agonists in the treatment of autoimmune diseases: selective targeting of myeloid but not plasmacytoid dendritic cells

scientific article published on December 2007

Vitamin D receptor agonists target static, dynamic, and inflammatory components of benign prostatic hyperplasia

scientific article published on April 2010

Vitamin D receptor agonists, cancer and the immune system: an intricate relationship

scientific article

List of works by Giuseppe Penna

1,25-Dihydroxyvitamin D3 selectively modulates tolerogenic properties in myeloid but not plasmacytoid dendritic cells

A gut-vascular barrier controls the systemic dissemination of bacteria.

A vitamin D analog down-regulates proinflammatory chemokine production by pancreatic islets inhibiting T cell recruitment and type 1 diabetes development.

BALB/c and C57BL/6 Mice Differ in Polyreactive IgA Abundance, which Impacts the Generation of Antigen-Specific IgA and Microbiota Diversity

Calcitriol derivatives with two different side chains at C-20 III. An epimeric pair of the gemini family with unprecedented antiproliferative effects on tumor cells and renin mRNA expression inhibition.

Chronic inflammation in the pathogenesis of benign prostatic hyperplasia.

Coagulation induced by C3aR-dependent NETosis drives protumorigenic neutrophils during small intestinal tumorigenesis.

Control of autoimmune diseases by the vitamin D endocrine system

Cutting edge: differential chemokine production by myeloid and plasmacytoid dendritic cells

Cutting edge: selective usage of chemokine receptors by plasmacytoid dendritic cells

Delivery to the central nervous system of a nonreplicative herpes simplex type 1 vector engineered with the interleukin 4 gene protects rhesus monkeys from hyperacute autoimmune encephalomyelitis

Dendritic cell tolerogenicity: a key mechanism in immunomodulation by vitamin D receptor agonists.

Dendritic cells as key targets for immunomodulation by Vitamin D receptor ligands

Deviation of pancreas-infiltrating cells to Th2 by interleukin-12 antagonist administration inhibits autoimmune diabetes

Dichotomy of short and long thymic stromal lymphopoietin isoforms in inflammatory disorders of the bowel and skin

Differential migration behavior and chemokine production by myeloid and plasmacytoid dendritic cells.

Early Th1 response in unprimed nonobese diabetic mice to the tyrosine phosphatase-like insulinoma-associated protein 2, an autoantigen in type 1 diabetes

Efficacy of a potent and safe vitamin D receptor agonist for the treatment of inflammatory bowel disease

Expression of the inhibitory receptor ILT3 on dendritic cells is dispensable for induction of CD4+Foxp3+ regulatory T cells by 1,25-dihydroxyvitamin D3.

Farnesoid X receptor activation inhibits inflammation and preserves the intestinal barrier in inflammatory bowel disease

Functional maturation of adult mouse resting microglia into an APC is promoted by granulocyte-macrophage colony-stimulating factor and interaction with Th1 cells

Genomic diversity and immunomodulatory activity of Lactobacillus plantarum isolated from dairy products

Human benign prostatic hyperplasia stromal cells as inducers and targets of chronic immuno-mediated inflammation.

Human immunodeficiency virus type 1 gp120 and other activation stimuli are highly effective in triggering alpha interferon and CC chemokine production in circulating plasmacytoid but not myeloid dendritic cells.

IL-12 production by central nervous system microglia is inhibited by astrocytes ⬇️

Induction of macrophage-derived chemokine/CCL22 expression in experimental autoimmune encephalomyelitis and cultured microglia: implications for disease regulation

Induction of transplantation tolerance by 1,25-dihydroxyvitamin D(3).

Inhibition of costimulatory pathways for T-cell activation by 1,25-dihydroxyvitamin D(3).

Inhibition of prostate growth and inflammation by the vitamin D receptor agonist BXL-628 (elocalcitol)

Lactobacillus paracasei CBA L74 metabolic products and fermented milk for infant formula have anti-inflammatory activity on dendritic cells in vitro and protective effects against colitis and an enteric pathogen in vivo

Manipulating dendritic cells to induce regulatory T cells.

Oral tolerance can be established via gap junction transfer of fed antigens from CX3CR1⁺ macrophages to CD103⁺ dendritic cells

Pharmacological induction of tolerogenic dendritic cells and regulatory T cells.

Polymorphisms in the Il12b gene affect structure and expression of IL-12 in NOD and other autoimmune-prone mouse strains.

Probiotic and postbiotic activity in health and disease: comparison on a novel polarised ex-vivo organ culture model

Seminal plasma cytokines and chemokines in prostate inflammation: interleukin 8 as a predictive biomarker in chronic prostatitis/chronic pelvic pain syndrome and benign prostatic hyperplasia

Spontaneous and prostatic steroid binding protein peptide-induced autoimmune prostatitis in the nonobese diabetic mouse

Synthesis and anti-inflammatory properties of 1alpha,25-dihydroxy-16-ene-20-cyclopropyl-24-oxo-vitamin D3, a hypocalcemic, stable metabolite of 1alpha,25-dihydroxy-16-ene-20-cyclopropyl-vitamin D3.

The EGFR-specific antibody cetuximab combined with chemotherapy triggers immunogenic cell death.

The vitamin D receptor agonist elocalcitol inhibits IL-8-dependent benign prostatic hyperplasia stromal cell proliferation and inflammatory response by targeting the RhoA/Rho kinase and NF-kappaB pathways

Thiol antioxidants inhibit the formation of the interleukin-12 heterodimer: a novel mechanism for the inhibition of IL-12 production.

Tolerogenic dendritic cells induced by vitamin D receptor ligands enhance regulatory T cells inhibiting allograft rejection and autoimmune diseases.

Treatment of experimental autoimmune prostatitis in nonobese diabetic mice by the vitamin D receptor agonist elocalcitol

Vitamin D receptor agonists as anti-inflammatory agents

Vitamin D receptor agonists in the treatment of autoimmune diseases: selective targeting of myeloid but not plasmacytoid dendritic cells

Vitamin D receptor agonists target static, dynamic, and inflammatory components of benign prostatic hyperplasia

Vitamin D receptor agonists, cancer and the immune system: an intricate relationship