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List of works by Sebastiaan Heidt

A Memory B Cell Crossmatch Assay for Quantification of Donor-Specific Memory B Cells in the Peripheral Blood of HLA-Immunized Individuals.

scientific article

A NOVel ELISPOT assay to quantify HLA-specific B cells in HLA-immunized individuals

scientific article published on 05 March 2012

A paired kidney analysis on the impact of pre-transplant anti-HLA antibodies on graft survival

scientific article published on 01 June 2019

A subset of anti-HLA antibodies induces FcγRIIa-dependent platelet activation

scholarly article by Maaike Rijkers et al published October 2018 in Haematologica

Allocation to highly sensitized patients based on acceptable mismatches results in low rejection rates comparable to nonsensitized patients

scientific article published on 01 July 2019

An Easy and Sensitive Method to Profile the Antibody Specificities of HLA-specific Memory B Cells

scientific article published on 01 April 2019

Anti-HLA antibodies with complementary and synergistic interaction geometries promote classical complement activation on platelets

scientific article published on 27 September 2018

Antibodies against ARHGDIB are associated with long-term kidney graft loss

scientific article published on 03 July 2019

Autologous bone marrow derived mesenchymal stromal cell therapy in combination with everolimus to preserve renal structure and function in renal transplant recipients

scientific article

B Cell Immunity in Solid Organ Transplantation.

scientific article published on January 2016

B Cell Markers of Operational Tolerance Can Discriminate Acute Kidney Allograft Rejection From Stable Graft Function

scientific article published on 21 October 2014

B cell repopulation after alemtuzumab induction-transient increase in transitional B cells and long-term dominance of naïve B cells.

scientific article published on 15 March 2012

BIOMARKERS OF OPERATIONAL TOLERANCE IN SOLID ORGAN TRANSPLANTATION.

scientific article published on July 2012

Beneficial Immune Effects of Myeloid-Related Proteins in Kidney Transplant Rejection.

scientific article published on 26 November 2015

Blood cell mRNAs and microRNAs: optimized protocols for extraction and preservation.

scientific article published on 17 January 2013

Calcineurin inhibitors affect B cell antibody responses indirectly by interfering with T cell help.

scientific article published on 18 November 2009

Cross-Reactivity of Virus-Specific CD8+ T Cells Against Allogeneic HLA-C: Possible Implications for Pregnancy Outcome

scientific article published on 06 December 2018

Defining the immunogenicity and antigenicity of HLA epitopes is crucial for optimal epitope matching in clinical renal transplantation

scientific article

Detecting the humoral alloimmune response: we need more than serum antibody screening.

scientific article published on May 2015

Development and Validation of a Multiplex Non-HLA Antibody Assay for the Screening of Kidney Transplant Recipients

scientific article published on 19 December 2018

Differential effects of donor-specific HLA antibodies in living- versus deceased-donor transplantation.

scientific article published on 21 February 2018

Effect of initial immunosuppression on long-term kidney transplant outcome in immunological low-risk patients

scientific article published on 01 August 2019

Epitope-Based HLA Matching: A Useful Strategy With Many Shortcomings to Overcome.

scientific article published in March 2017

Generation and reactivity analysis of human recombinant monoclonal antibodies directed against epitopes on HLA-DR

scientific article published on 28 April 2020

HLA-specific memory B-cell detection in kidney transplantation: Insights and future challenges

scientific article published on 10 May 2020

How can we reduce costs of solid-phase multiplex-bead assays used to determine anti-HLA antibodies?

scientific article published on 18 August 2016

How the definition of acceptable antigens and epitope analysis can facilitate transplantation of highly sensitized patients with excellent long-term graft survival

scientific article published on 01 August 2018

Immunogenetics and immunology of transplantation in Leiden.

scientific article published on 22 September 2014

Increased HLA-G Expression in Term Placenta of Women with a History of Recurrent Miscarriage Despite Their Genetic Predisposition to Decreased HLA-G Levels ⬇️

scientific article published on 01 February 2019

Infectious pathogens may trigger specific allo-HLA reactivity via multiple mechanisms.

scientific article

Kidney allocation based on proven acceptable antigens results in superior graft survival in highly sensitized patients

scientific article published on 22 September 2017

Minimal data reporting standards for serological testing for histocompatibility

scientific article published on 17 August 2018

Monitoring B cell subsets and alloreactivity in kidney transplantation.

scientific article published on 21 February 2015

Monitoring of indirect allorecognition: wishful thinking or solid data?

scientific article

No Evidence for Cross-reactivity of Virus-specific Antibodies With HLA Alloantigens

scientific article published on 13 July 2018

Novel aspects of epitope matching and practical application in kidney transplantation.

scientific article published on 20 October 2017

PIRCHE-II Is Related to Graft Failure after Kidney Transplantation

scientific article published on 5 March 2018

Peripheral blood sampling for the detection of allograft rejection: biomarker identification and validation.

scientific article published on July 2011

Polyclonal B cell activation for accurate analysis of pre-existing antigen-specific memory B cells

scientific article

Presence of intragraft B cells during acute renal allograft rejection is accompanied by changes in peripheral blood B cell subsets

scientific article published on 17 February 2019

Pretransplant C3d-Fixing Donor-Specific Anti-HLA Antibodies Are Not Associated with Increased Risk for Kidney Graft Failure

scientific article published on 26 July 2018

Pretransplant Serum CXCL9 and CXCL10 Levels Fail to Predict Acute Rejection in Kidney Transplant Recipients Receiving Induction Therapy ⬇️

scientific article published on April 27, 2011

Preventing Memory B Cell Formation: A Story of Mice and Men?

scientific article published on 29 June 2016

Proteasome inhibition profoundly affects activated human B cells.

scientific article

Quantification of HLA class II-specific memory B cells in HLA-sensitized individuals.

scientific article published on 27 January 2015

Regulatory B cells: Phenotype, function and role in transplantation

scientific article published on 28 February 2017

Restricted specificity of peripheral alloreactive memory B cells in HLA-sensitized patients awaiting a kidney transplant.

scientific article published on 7 January 2015

Safety of allogeneic bone marrow derived mesenchymal stromal cell therapy in renal transplant recipients: the neptune study

scientific article

T-cell alloreactivity and transplantation outcome: a budding role for heterologous immunity?

scientific article published on August 2015

Technical challenges and clinical relevance of single antigen bead C1q/C3d testing and IgG subclass analysis of human leukocyte antigen antibodies

scientific article published on 24 August 2018

Th17: Contributors to Allograft Rejection and a Barrier to the Induction of Transplantation Tolerance? ⬇️

scientific article published on May 15, 2011

The 25th anniversary of the Eurotransplant Acceptable Mismatch program for highly sensitized patients

scientific article published on 28 August 2015

The long and winding road towards epitope matching in clinical transplantation

scientific article published on 26 November 2018

The number of FoxP3 regulatory T cells in the circulation may be a predictive biomarker for kidney transplant recipients: A multistage systematic review

scientific article published on 01 November 2018

Toward a Sensible Single-antigen Bead Cutoff Based on Kidney Graft Survival

scientific article published on 01 April 2019

Transplantation in highly sensitized patients: challenges and recommendations

scientific article published on 13 July 2018

What is wrong with the regulatory T cells and foetomaternal tolerance in women with recurrent miscarriages?

scientific article published on 3 February 2016

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