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List of works by George K. Radda

A new hyperpolarized C ketone body probe reveals an increase in acetoacetate utilization in the diabetic rat heart

Abnormal cardiac and skeletal muscle energy metabolism in patients with type 2 diabetes

scientific article

Abnormal cardiac morphology, function and energy metabolism in the dystrophic mdx mouse: an MRI and MRS study

scientific article

Accumulation of 2-deoxy-D-glucose-6-phosphate as a measure of glucose uptake in the isolated perfused heart: a 31P NMR study

scientific article

An analysis of cancer research funding in the UK.

scientific article published in February 2003

Bone marrow-derived stromal cells home to and remain in the infarcted rat heart but fail to improve function: an in vivo cine-MRI study.

scientific article published on 6 June 2008

Brain bioenergetics and cognitive ability

scientific article published in September 2003

Determining the in vivo regulation of cardiac pyruvate dehydrogenase based on label flux from hyperpolarised [1‐13C]pyruvate ⬇️

scientific article published on March 8, 2011

Downregulating serine hydroxymethyltransferase 2 (SHMT2) suppresses tumorigenesis in human hepatocellular carcinoma

scientific article published on 6 July 2016

FoxO1 inhibits leptin regulation of pro-opiomelanocortin promoter activity by blocking STAT3 interaction with specificity protein 1.

scientific article

FoxO1 negatively regulates leptin-induced POMC transcription through its direct interaction with STAT3

scientific article published on 01 March 2015

From gene function to improved health: genome research in the United Kingdom

scientific article published on 8 January 2004

Gastrointestinal transit measurements in mice with 99mTc-DTPA-labeled activated charcoal using NanoSPECT-CT.

scientific article

Gender differences in hypertrophy, insulin resistance and ischemic injury in the aging type 2 diabetic rat heart

scientific article

Glucose intolerance and impaired insulin secretion in pancreas-specific signal transducer and activator of transcription-3 knockout mice are associated with microvascular alterations in the pancreas

scientific article

Image promotion

scientific article published in Nature

Imaging metabolic syndrome

scientific article

Impaired in vivo mitochondrial Krebs cycle activity after myocardial infarction assessed using hyperpolarized magnetic resonance spectroscopy.

scientific article published on 8 September 2014

Impaired insulin secretion and glucose intolerance in synaptotagmin-7 null mutant mice

scientific article

In Vivo Hyperpolarized Carbon-13 Magnetic Resonance Spectroscopy Reveals Increased Pyruvate Carboxylase Flux in an Insulin-Resistant Mouse Model ⬇️

scientific article published on January 10, 2013

In vivo assessment of pyruvate dehydrogenase flux in the heart using hyperpolarized carbon-13 magnetic resonance

scholarly article

Increased Lipolysis and Energy Expenditure in a Mouse Model with Severely Impaired Glucagon Secretion ⬇️

scientific article published on October 27, 2011

Initial steps of insulin signaling and glucose transport are defective in the type 2 diabetic rat heart

scientific article published on February 2004

Insulin resistance, abnormal energy metabolism and increased ischemic damage in the chronically infarcted rat heart.

scientific article published on 10 March 2006

Iron particles for noninvasive monitoring of bone marrow stromal cell engraftment into, and isolation of viable engrafted donor cells from, the heart

scientific article published on 20 April 2006

Loss of BCAA Catabolism during Carcinogenesis Enhances mTORC1 Activity and Promotes Tumor Development and Progression

scientific article published on 17 January 2019

Measuring intracellular pH in the heart using hyperpolarized carbon dioxide and bicarbonate: a 13C and 31P magnetic resonance spectroscopy study

scientific article

Misfolded Protein Linked Strategies Toward Biomarker Development for Neurodegenerative Diseases

scientific article published on 24 July 2018

Molecular imaging perspectives

scientific article published on June 2005

Nanotheranostic agents for neurodegenerative diseases

scientific article published on 15 December 2020

Neonatal overnutrition in mice exacerbates high-fat diet-induced metabolic perturbations ⬇️

scientific article published on October 4, 2013

Neuronal calcium sensor synaptotagmin-9 is not involved in the regulation of glucose homeostasis or insulin secretion

scientific article

Oxygenation dependence of the transverse relaxation time of water protons in whole blood at high field

scientific article

PPAR-alpha activation required for decreased glucose uptake and increased susceptibility to injury during ischemia

scientific article published on 21 January 2005

Public views of UK Population Biomedical Collection are being taken into account

scientific article

Real-time assessment of Krebs cycle metabolism using hyperpolarized 13C magnetic resonance spectroscopy.

scientific article published on 27 March 2009

Reduced body weight and increased energy expenditure in transgenic mice over-expressing soluble leptin receptor

scientific article

Regulation of adipogenesis by cytoskeleton remodelling is facilitated by acetyltransferase MEC-17-dependent acetylation of α-tubulin

scientific journal article

Robust hyperpolarized (13)C metabolic imaging with selective non-excitation of pyruvate (SNEP).

scientific article published on 28 June 2015

Role of pyruvate dehydrogenase inhibition in the development of hypertrophy in the hyperthyroid rat heart: a combined magnetic resonance imaging and hyperpolarized magnetic resonance spectroscopy study.

scientific article

Science in Europe. Biomedical research and international collaboration

scientific article

Seipin differentially regulates lipogenesis and adipogenesis through a conserved core sequence and an evolutionarily acquired C-terminus

scientific article

Simultaneous determination of low free Mg2+ and pH in human sickle cells using 31P NMR spectroscopy

scientific article published on 23 September 2002

Spatial localization of high resolution 31P spectra with a surface coil

Straight talk with...George Radda. Interview by David Cyranoski

scientific article published in May 2011

Suppression of Adipogenesis by Pathogenic Seipin Mutant Is Associated with Inflammatory Response ⬇️

scientific article published on March 8, 2013

Synaptotagmin-7 is a principal Ca2+ sensor for Ca2+ -induced glucagon exocytosis in pancreas

scientific article

The cycling of acetyl-coenzyme A through acetylcarnitine buffers cardiac substrate supply: a hyperpolarized 13C magnetic resonance study.

scientific article

The effect of hyperpolarized tracer concentration on myocardial uptake and metabolism

scientific article published in May 2009

The mechanism underlying the positive inotropic effect of angiotensin II in the isolated perfused rabbit heart: a 31P NMR study

scientific article published in June 2003

Transposon mutagenesis identifies genes driving hepatocellular carcinoma in a chronic hepatitis B mouse model

scientific article

Uncoupling proteins in human heart

scientific article published in November 2004

Validation of the in vivo assessment of pyruvate dehydrogenase activity using hyperpolarised 13C MRS.

scientific article published on 26 August 2010

Visualization and isolation of Langerhans islets by a fluorescent probe PiY.

scientific article published on 28 May 2013

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