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List of works by George Perry

1,3-propanediol binds deep inside the channel to inhibit water permeation through aquaporins

scientific article published on 20 October 2015

2009 award recipients--Peter C. Burger, MD, Pierluigi Gambetti, MD, and Nicholas K. Gonatas, MD.

scientific article published in November 2009

4-Hydroxynonenal contributes to NGF withdrawal-induced neuronal apoptosis

article published in 2003

4-Hydroxynonenal-derived advanced lipid peroxidation end products are increased in Alzheimer's disease

scientific article published in May 1997

4-Oxo-2-nonenal is both more neurotoxic and more protein reactive than 4-hydroxy-2-nonenal

scientific article published on August 2005

4-hydroxynonenal contributes to NGF withdrawal-induced neuronal apoptosis

scientific article published in May 2003

A clinical study of lupron depot in the treatment of women with Alzheimer's disease: preservation of cognitive function in patients taking an acetylcholinesterase inhibitor and treated with high dose lupron over 48 weeks

scientific article

A low-molecular-weight ferroxidase is increased in the CSF of sCJD cases: CSF ferroxidase and transferrin as diagnostic biomarkers for sCJD.

scientific article published on 16 April 2013

A metabolic basis for Alzheimer disease

scientific article published on October 2003

A multilevel view of the development of Alzheimer's Disease

scientific article published on 24 November 2020

A new model of oxidative stress in rat pups

scientific article

A novel approach to the identification and quantitative elemental analysis of amyloid deposits--insights into the pathology of Alzheimer's disease

scientific article published in March 2009

A novel endogenous indole protects rodent mitochondria and extends rotifer lifespan

scientific article

A novel origin for granulovacuolar degeneration in aging and Alzheimer's disease: parallels to stress granules

scientific article

A novel perspective on tau in Alzheimer's disease

scientific article published on September 2011

A second look into the oxidant mechanisms in Alzheimer's disease

scientific article

A suicide note from Alzheimer disease neurons?

scientific article published in August 1998

A synergistic dysfunction of mitochondrial fission/fusion dynamics and mitophagy in Alzheimer's disease

scientific article

ADF/cofilin-actin rods and synaptic loss in Alzheimer's disease

ADVANCED GLYCATION AND LIPID MODIFICATION OF ROSENTHAL FIBERS IN ALEXANDERʼS DISEASE

AGEs/RAGE complex upregulates BACE1 via NF-κB pathway activation

scientific article published on 17 July 2010

APP transgenesis: approaches toward the development of animal models for Alzheimer disease neuropathology

scientific article

Aberrant expression of metabotropic glutamate receptor 2 in the vulnerable neurons of Alzheimer's disease

scientific article published on 11 February 2004

Aberrant localization of importin alpha1 in hippocampal neurons in Alzheimer disease

scientific article published on 27 October 2006

Aberrant phosphoinositide metabolism in Alzheimer's disease

scientific article

Abnormal localization of iron regulatory protein in Alzheimer's disease ⬇️

scientific article published on March 30, 1998

Abnormal mitochondrial dynamics and neurodegenerative diseases

scientific article published on 30 September 2009

Abnormal mitochondrial dynamics in the pathogenesis of Alzheimer's disease

scientific article

Abnormal mitochondrial dynamics--a novel therapeutic target for Alzheimer's disease?

scientific article published on 27 January 2010

Abnormal tau-reactive filaments in olfactory mucosa in biopsy specimens of patients with probable Alzheimer's disease

scientific article published in March 1991

Abortive apoptosis in Alzheimer's disease

scientific article

Accelerated alpha-synuclein aggregation after differentiation of SH-SY5Y neuroblastoma cells

scientific article published on July 2004

Accumulation of intraneuronal amyloid-β is common in normal brain

scientific article

Accumulation of the beta amyloid precursor protein at sites of ischemic injury in rat brain.

scientific article published in February 1993

Acetylcholinesterase and its association with heparan sulphate proteoglycans in cortical amyloid deposits of Alzheimer's disease

scientific article published in November 1992

Activation and redistribution of c-jun N-terminal kinase/stress activated protein kinase in degenerating neurons in Alzheimer's disease

scientific article published in January 2001

Activation of MKK6, an upstream activator of p38, in Alzheimer's disease

scientific article

Activation of NADPH oxidase in Alzheimer's disease brains

scientific article published in June 2000

Activation of P38 kinase links π phosphorylation, oxidative stress and cell cycle-related events in Alzheimer disease

Activation of neuronal extracellular receptor kinase (ERK) in Alzheimer disease links oxidative stress to abnormal phosphorylation

scientific article

Active glycation in neurofibrillary pathology of Alzheimer disease: N(epsilon)-(carboxymethyl) lysine and hexitol-lysine

scientific article published in July 2001

Advanced Maillard Reaction End Products, Free Radicals, and Protein Oxidation in Alzheimer's Diseasea

Advanced Maillard reaction end products are associated with Alzheimer disease pathology

scientific article published on June 1994

Advanced Maillard reaction end products, free radicals, and protein oxidation in Alzheimer's disease

scientific article published on November 1994

Advanced glycation modification of Rosenthal fibers in patients with Alexander disease ⬇️

scientific article published on August 8, 1997

Advanced lipid peroxidation end-products in Alexander's disease

scientific article published in March 1998

Advances in Alzheimer's Diagnosis and Therapy: The Implications of Nanotechnology

scientific article published on 27 June 2017

Adventiously-bound redox active iron and copper are at the center of oxidative damage in Alzheimer disease

scientific article

Affinity and path of binding xylopyranose unto E. coli xylose permease

scientific article published on 11 October 2017

Alexander disease: Alzheimer disease of the developing brain?

scientific article published in October 1999

All-trans retinoic acid as a novel therapeutic strategy for Alzheimer's disease

scientific article

Alpha 1-antitrypsin and alpha 1-antichymotrypsin are in the lesions of Alzheimer's disease

scientific article published in February 1992

Alpha 1-trypsin immunoreactivity in Alzheimer disease

scientific article published in June 1993

Alteration of neuritic cytoarchitecture in Alzheimer disease

scientific article published on January 1989

Alteration of phospholipase C-delta protein level and specific activity in Alzheimer's disease

scientific article published in June 1995

Alteration of proteins regulating apoptosis, Bcl-2, Bcl-x, Bax, Bak, Bad, ICH-1 and CPP32, in Alzheimer's disease

scientific article published in January 1998

Alterations of low molecular weight acid phosphatase protein level in Alzheimer's disease

scientific article published in November 1995

Alterations of the X Chromosome in Lymphocytes of Alzheimer's Disease Patients

scientific article

Altered redox balance in disease: Can we change the new equilibria?

Alternative neural circuitry that might be impaired in the development of Alzheimer disease

scientific article

Alz 50 recognizes abnormal filaments in Alzheimer's disease and progressive supranuclear palsy

scientific article published in September 1988

Alzheimer Disease Pathology in Middle Age Reveals a Spatial-Temporal Disconnect Between Amyloid-β and Phosphorylated Tau

scientific article

Alzheimer Disease and Oxidative Stress

scientific article

Alzheimer Disease: Oxidative Stress and Compensatory Responses

article

Alzheimer disease and the role of free radicals in the pathogenesis of the disease

scientific article published on February 2008

Alzheimer disease pathology as a host response

scientific article published on June 2008

Alzheimer disease research in the 21st century: past and current failures, new perspectives and funding priorities

scientific article published on 04 May 2016

Alzheimer disease, the two-hit hypothesis: an update

scientific article published on 27 October 2006

Alzheimer disease: an imbalance of proteolytic regulation?

scientific article published in April 1994

Alzheimer disease: evidence for a central pathogenic role of iron-mediated reactive oxygen species

scientific article published on April 2004

Alzheimer disease: protein-protein interaction and oxidative stress

scientific article published on January 1, 1996

Alzheimer's Disease

Alzheimer's Disease: Advances for a New Century

scholarly article by George Perry et al published 27 December 2012 in Journal of Alzheimer's Disease

Alzheimer's Disease: An Overview☆

scholarly article published 2014

Alzheimer's and Parkinson's Disease Novel Therapeutic Target

scientific article published in 2017

Alzheimer's disease and prion proteins: a meeting made in muscle.

scientific article published on December 1994

Alzheimer's disease and vascular deficiency: lessons from imaging studies and down syndrome

scientific article published on 15 February 2012

Alzheimer's disease: an intracellular movement disorder?

scientific article published in September 2005

Alzheimer's disease: cerebrovascular dysfunction, oxidative stress, and advanced clinical therapies

scientific article published on October 2008

Alzheimer's disease: diverse aspects of mitochondrial malfunctioning

scientific article

Alzheimer's disease: the two-hit hypothesis

scientific article published on April 2004

Alzheimer's plaques re-created in a test tube: Further insights into the mechanism of amyloid plaque formation

Alzheimer-specific epitopes of tau represent lipid peroxidation-induced conformations

scientific article

Alzheimers Disease and Oxidative Stress: The Old Problem Remains Unsolved

scholarly article published 1 March 2005

Alzheimer’s Disease: An Overview

article

Alzheimer’s disease therapy: a moving target

Amyloid Beta and tau proteins as therapeutic targets for Alzheimer's disease treatment: rethinking the current strategy

scientific article published on 8 March 2012

Amyloid P component and other acute-phase proteins associated with cerebellar A beta-deposits in Alzheimer's disease

scientific article published in December 1993

Amyloid beta: the alternate hypothesis

scientific article

Amyloid precursor protein in cell cultures: a 130 kDa polypeptide

scientific article published in January 1989

Amyloid precursor protein in senile plaques of Alzheimer disease

scientific article published in September 1988

Amyloid β peptides modify the expression of antioxidant repair enzymes and a potassium channel in the septohippocampal system

scientific article published on 07 March 2013

Amyloid β-mediated Zn2+ influx into dentate granule cells transiently induces a short-term cognitive deficit

scientific article published on 23 December 2014

Amyloid-beta and tau serve antioxidant functions in the aging and Alzheimer brain

scientific article

Amyloid-beta deposition in Alzheimer transgenic mice is associated with oxidative stress

scientific article published in May 1998

Amyloid-beta in Alzheimer Disease: The Null versus the Alternate Hypotheses

article

Amyloid-beta in Alzheimer's disease: the horse or the cart? Pathogenic or protective?

scientific article

Amyloid-beta vaccination: testing the amyloid hypothesis?: heads we win, tails you lose!

scientific article published on September 2006

Amyloid-beta, BACE, and oxidative stress in Alzheimer's disease, a commentary on "The different aggregation state of beta-amyloid 1-42 mediates different effects on oxidative stress, neurodegeneration and BACE-1 expression"

scientific article published on 04 May 2006

Amyloid-beta, tau alterations and mitochondrial dysfunction in Alzheimer disease: the chickens or the eggs?

scientific article

Amyloid-beta-derived diffusible ligands cause impaired axonal transport of mitochondria in neurons

scientific article published on 13 February 2010

Amyloid-beta-induced toxicity of primary neurons is dependent upon differentiation-associated increases in tau and cyclin-dependent kinase 5 expression

scientific article published in February 2004

Amyloid-beta: a (life) preserver for the brain

scientific article published in November 2002

Amyloid-beta: a vascular sealant that protects against hemorrhage?

scientific article

Amyloid-β Deposition in Alzheimer Transgenic Mice Is Associated with Oxidative Stress

article published in 2002

Amyloid-β junkies

scientific article published in The Lancet

Amyloid-β peptide structure in aqueous solution varies with fragment size

scientific article

Amyloid-β: a chameleon walking in two worlds: a review of the trophic and toxic properties of amyloid-β

article

Amyloidosis, advanced glycation end products and Alzheimer disease

scientific article published in August 1995

Amyloids, Aggregates and Neuronal Inclusions: Good or Bad News for Neurons?

article

Amyotrophic lateral sclerosis: a novel hypothesis involving a gained 'loss of function' in the JNK/SAPK pathway

scientific article

An Inducible Alpha-Synuclein Expressing Neuronal Cell Line Model for Parkinson's Disease1

scientific article published on 01 January 2018

Analysis of post-translational modifications in Alzheimer's disease by mass spectrometry

scientific article published on 24 November 2018

Analysis of the Relationship Between Metalloprotease-9 and Tau Protein in Alzheimer's Disease

scientific article published on 06 June 2020

Anthocyanins: Possible role as Multitarget therapeutic agents for prevention and therapy of chronic diseases.

scientific article

Antibodies to neurofibrillary tangles of Alzheimer's disease raised from human and animal neurofilament fractions

scientific article published in October 1983

Antibodies to potato virus Y bind the amyloid beta peptide: immunohistochemical and NMR studies

scientific article published on 27 May 2008

Antibodies to the neuronal cytoskeleton are elicited by Alzheimer paired helical filament fractions

scientific article

Antigen-antibody dissociation in Alzheimer disease: a novel approach to diagnosis

scientific article

Antimicrobial peptide β-defensin-1 expression is upregulated in Alzheimer's brain

scientific article published on 18 October 2013

Antioxidant approaches for the treatment of Alzheimer's disease

scientific article published on July 2010

Antioxidant protection and neurodegenerative disease: the role of amyloid-beta and tau.

scientific article

Antioxidant therapy in Alzheimer's disease: theory and practice

scientific article

Apolipoprotein E4 prevents growth of malaria at the intraerythrocyte stage: implications for differences in racial susceptibility to Alzheimer's disease

scientific article

Apoptosis in Alzheimer disease: a mathematical improbability

scientific article published on September 2006

Apoptotic and Oxidative Indicators in Alzheimer's Disease

scholarly article

Apoptotic promoters and inhibitors in Alzheimer's disease: Who wins out?

scientific article

Applicability of in vivo staging of regional amyloid burden in a cognitively normal cohort with subjective memory complaints: the INSIGHT-preAD study

scientific article published on 31 January 2019

Are Alzheimer's Disease and Aging Evolutionary?

scholarly article by George Perry et al published 6 May 2013 in Journal of Alzheimer's Disease

Arson. Tracking the culprit in Alzheimer's disease

scientific article

Artifactual strain-specific signs of incipient brain amyloidosis in APP transgenic mice

scientific article published in March 1996

Assembly in vitro of tau protein and its implications in Alzheimer's disease.

scientific article

Association of Mitochondrial Signaling in Alzheimer’s Disease and Hypoxia

Association of cerebrospinal fluid α-synuclein with total and phospho-tau181 protein concentrations and brain amyloid load in cognitively normal subjective memory complainers stratified by Alzheimer's disease biomarkers

scientific article published on 26 July 2018

Association of heparan sulfate proteoglycan with the neurofibrillary tangles of Alzheimer's disease

scientific article published on November 1991

Astrocytes regulate microglial phagocytosis of senile plaque cores of Alzheimer's disease

scientific article

Atherosclerotic lesions and mitochondria DNA deletions in brain microvessels as a central target for the development of human AD and AD-like pathology in aged transgenic mice

scientific article published in November 2002

Atherosclerotic lesions and mitochondria DNA deletions in brain microvessels: implication in the pathogenesis of Alzheimer's disease

scientific article published on January 2008

Atherosclerotic lesions are associated with increased immunoreactivity for inducible nitric oxide synthase and endothelin-1 in thoracic aortic intimal cells of hyperlipidemic Watanabe rabbits.

scientific article

Autophagocytosis of mitochondria is prominent in Alzheimer disease

scientific article

Autophagocytosis of mitochondria is prominent in Alzheimer disease

Autophagy in Alzheimer's disease

scientific article published on July 2010

Autophagy in Alzheimer’s disease: A Cleaning Service Out-of-order?

BARHL1 Is Downregulated in Alzheimer's Disease and May Regulate Cognitive Functions through ESR1 and Multiple Pathways

scientific article published on 28 September 2017

BRCA1 may modulate neuronal cell cycle re-entry in Alzheimer disease

scientific article published on 12 May 2007

Basic fibroblast growth factor binding is a marker for extracellular neurofibrillary tangles in Alzheimer disease

scientific article published in July 1991

Basic fibroblast growth factor binds to filamentous inclusions of neurodegenerative diseases

scientific article published in May 1992

Behavioral Abnormality Induced by Enhanced Hypothalamo-Pituitary-Adrenocortical Axis Activity under Dietary Zinc Deficiency and Its Usefulness as a Model

scientific article

Beta protein immunoreactivity is found in the majority of neurofibrillary tangles of Alzheimer's disease ⬇️

scientific article published on February 1, 1992

Beta-amyloid 1-42 monomers, but not oligomers, produce PHF-like conformation of Tau protein

scientific article published on 12 July 2016

Beta-site APP cleaving enzyme up-regulation induced by 4-hydroxynonenal is mediated by stress-activated protein kinases pathways.

scientific article published on February 2005

Beyond estrogen: targeting gonadotropin hormones in the treatment of Alzheimer's disease

scientific article published in August 2004

Biochemistry of neurodegeneration

scientific article published in January 2001

Biomarkers in Alzheimer's disease: past, present and future

scientific article

Birth of JAD: 20 Years Later.

scientific article published in January 2018

Brain Composition: Age-Related Changes

article

Brain and brawn: parallels in oxidative strength

scientific article

CD3 in Lewy pathology: does the abnormal recall of neurodevelopmental processes underlie Parkinson's disease

scientific article

CI-ATPase and Na+/K(+)-ATPase activities in Alzheimer's disease brains

scientific article published in October 1998

Ca2+-stimulated production of H2O2 from naphthoquinone oxidation in Arbacia eggs

article

Call for Elan to publish Alzheimer's trial details

scientific article published in April 2002

Carnosine: a versatile antioxidant and antiglycating agent

scientific article

Causes and consequences of oxidative stress in Alzheimer's disease

scientific article

Causes of oxidative stress in Alzheimer disease.

scientific article published on September 2007

Causes versus effects: the increasing complexities of Alzheimer's disease pathogenesis

scientific article

Cell cycle re-entry mediated neurodegeneration and its treatment role in the pathogenesis of Alzheimer's disease

scientific article published on 09 December 2008

Cellular Respiration and Tumor Suppressor Genes

article

Cellular prion protein is essential for oligomeric amyloid-β-induced neuronal cell death

scientific article published on 18 November 2011

Cerebral amyloid angiopathy: major contributor or decorative response to Alzheimer's disease pathogenesis

scientific article published on May 2004

Cerebral hemorrhage and amyloid-beta

scientific article published in February 2003

Cerebrotendinous xanthomatosis: a critical update

article published in 2008

Cerebrotendinous xanthomatosis: case report with evidence of oxidative stress

scientific article

Cerebrovascular and mitochondrial abnormalities in Alzheimer's disease: a brief overview

scientific article

Cerebrovascular muscle atrophy is a feature of Alzheimer's disease

scientific article published in April 1998

Cerebrovascular requirement for sealant, anti-coagulant and remodeling molecules that allow for the maintenance of vascular integrity and blood supply

article

Challenging the amyloid cascade hypothesis: senile plaques and amyloid-beta as protective adaptations to Alzheimer disease

scientific article published in June 2004

Chapter 19. Targeting Oxidative Mechanisms in Alzheimer Disease

Chapter 5 - Development of iron chelator-nanoparticle conjugates as potential therapeutic agents for Alzheimer disease

scientific article published on 08 December 2009

Characterization of Proteins Present in Isolated Senile Plaques from Alzheimer's Diseased Brains by MALDI-TOF MS with MS/MS.

scientific article published on 4 January 2018

Characterization of the association of phospholipase C-delta with Alzheimer neurofibrillary tangles

scientific article published on January 1995

Chemistry and biochemistry of oxidative stress in neurodegenerative disease

scientific article

Chitin-like polysaccharides in Alzheimer's disease brains

scientific article

Chlamydia pneumoniae promotes dysfunction of pancreatic beta cells

scientific article

Cholesterol homeostasis markers are localized to mouse hippocampal pyramidal and granule layers

scientific article published on August 2010

Cholesterol, oxidative stress, and Alzheimer's disease: expanding the horizons of pathogenesis

scientific article

Chondroitin sulfate proteoglycans are associated with the lesions of Alzheimer's disease

scientific article

Chronic antioxidant therapy reduces oxidative stress in a mouse model of Alzheimer's disease

scientific article published on February 2009

Chronic effects of mild neurotrauma: putting the cart before the horse?

scientific article

Chronic or late lyme neuroborreliosis: present and future

scientific article published on 5 October 2012

Chronic oxidative stress causes increased tau phosphorylation in M17 neuroblastoma cells

scientific article

Chronological primacy of oxidative stress in Alzheimer disease

scientific article published in May 2005

Ciprofloxacin Does Not Exert Nephrotoxicity in Rats

scholarly article

Cleavage and conformational changes of tau protein follow phosphorylation during Alzheimer's disease

scientific article published in April 2008

Cloning’s Promise

Clusterin up-regulation following sub-lethal oxidative stress and lipid peroxidation in human neuroblastoma cells

scientific article published on 7 February 2006

Coexistence of cytokeratin, vimentin and neurofilament protein in human choroid plexus. An immunohistochemical study of intermediate filaments in neuroepithelial tissues

scientific article published in January 1986

Cognitive decline due to excess synaptic Zn(2+) signaling in the hippocampus

scientific article published on 27 February 2014

Cognitive impairment in multiple system atrophy: a position statement by the Neuropsychology Task Force of the MDS Multiple System Atrophy (MODIMSA) study group

scientific article

Commentary on “Perspective on a pathogenesis and treatment of Alzheimer’s disease.” Therapeutic strategies for Alzheimer’s disease: The need for a new era of innovation

article

Commentary: "Ceramide and cholesterol: possible connections between normal aging of the brain and Alzheimer's disease. Just hypotheses or molecular pathways to be identified?" by Claudio Costantini, Rekha M.K. Kolasani, and Luigi Puglielli.

scientific article published in July 2005

Comparative biology and pathology of oxidative stress in Alzheimer and other neurodegenerative diseases: beyond damage and response

scientific article

Compensatory responses induced by oxidative stress in Alzheimer disease

scientific article

Competitive regulation of aβredox activity by copper and zinc: Parallels in the pathogenetic mechanisms of Alzheimer's disease and familial amyotrophic lateral sclerosis

scholarly article by Math P. Cuajungco et al published May 2000 in Neurobiology of Aging

Concealment of epitope by reduction and alkylation in prion protein

scientific article published in January 2005

Conformational changes and cleavage of tau in Pick bodies parallel the early processing of tau found in Alzheimer pathology

scientific article

Consequences of RNA oxidation on protein synthesis rate and fidelity: implications for the pathophysiology of neuropsychiatric disorders

scientific article

Contribution of redox-active iron and copper to oxidative damage in Alzheimer disease

scientific article published in July 2004

Contributors

Copernicus revisited: amyloid beta in Alzheimer's disease

scientific article

Copper Induces Apoptosis of Neuroblastoma Cells Via Post-translational Regulation of the Expression of Bcl-2-family Proteins and the tx Mouse is a Better Model of Hepatic than Brain Cu Toxicity

scientific article published on 20 January 2008

Copper mediates dityrosine cross-linking of Alzheimer's amyloid-beta

scientific article

Correction to: Transplantation of Human Chorion-Derived Cholinergic Progenitor Cells: a Novel Treatment for Neurological Disorders

scientific article published on 26 April 2018

Corrigendum

scholarly article published in Brain Research

Curcumin/melatonin hybrid 5-(4-hydroxy-phenyl)-3-oxo-pentanoic acid [2-(5-methoxy-1H-indol-3-yl)-ethyl]-amide ameliorates AD-like pathology in the APP/PS1 mouse model

scientific article published on 20 April 2015

Current Hypotheses and Research Milestones in Alzheimer's Disease

scholarly article published 2009

Current approaches in the treatment of Alzheimer's disease

scientific article published on 17 March 2008

Current needs for human and medical genomics research infrastructure in low and middle income countries

scientific article published on 06 January 2016

Cytochemical Demonstration of Oxidative Damage in Alzheimer Disease by Immunochemical Enhancement of the Carbonyl Reaction with 2,4-Dinitrophenylhydrazine ⬇️

scientific article published on June 1, 1998

DLP1-dependent mitochondrial fragmentation mediates 1-methyl-4-phenylpyridinium toxicity in neurons: implications for Parkinson's disease

scientific article published on 14 June 2011

DNA damage in Alzheimer disease lymphocytes and its relation to premature centromere division

scientific article

DOES THE OXIDATIVE STRESS AND CEREBRAL ATHEROSCLEROSIS INITIATE BRAIN HYPOPERFUSION AND THE DEVELOPMENT OF ALZHEIMER DISEASE?

Dangers of the amyloid-β vaccination

Decline in mitochondrial bioenergetics underlies central insulin resistance in streptozocin-induced model of sporadic Alzheimer's disease

scholarly article by Sónia Correia et al published July 2011 in Alzheimer's and Dementia

Deconstructing mitochondrial dysfunction in Alzheimer disease

scientific article published on 11 June 2013

Decreased constitutive nitric oxide synthase, but increased inducible nitric oxide synthase and endothelin-1 immunoreactivity in aortic endothelial cells of donryu rats on a cholesterol-enriched diet

scientific article published in September 2000

Degeneration of vascular muscle cells in cerebral amyloid angiopathy of Alzheimer disease

scientific article published in September 1993

Dementia Pugilistica Revisited

scientific article published on 8 October 2017

Dementia with argyrophilic grains

scientific article published in December 1991

Demonstration of a novel neurofilament associated antigen with the neurofibrillary pathology of Alzheimer and related diseases

scientific article published in August 1991

Detection and localization of markers of oxidative stress by in situ methods: application in the study of Alzheimer disease

scientific article published in January 2010

Diabetes mellitus and Alzheimer's disease: glycation as a biochemical link

scientific article published in February 1996

Diet and oxidative stress: a novel synthesis of epidemiological data on Alzheimer's disease

scientific article

Dietary flavonoids: Nano delivery and nanoparticles for cancer therapy

scientific article published on 24 August 2019

Differences in structure and function between human and murine tau

scientific article published on 12 August 2018

Differential activation of neuronal ERK, JNK/SAPK and p38 in Alzheimer disease: the ‘two hit’ hypothesis ⬇️

scientific article published on December 1, 2001

Differential network analyses of Alzheimer's disease identify early events in Alzheimer's disease pathology

scientific article

Differential regulation of glutamate receptors in Alzheimer's disease

scientific article

Dimethylargininase, a nitric oxide regulatory protein, in Alzheimer disease

scientific article published in November 1998

Diminished O-GlcNAcylation in Alzheimer's disease is strongly correlated with mitochondrial anomalies

scientific article published on 06 November 2018

Dissociated Aβ antibody level in newly diagnosed Alzheimer's disease: A population-based study

article

Dissociated amyloid-beta antibody levels as a serum biomarker for the progression of Alzheimer's disease: a population-based study

scientific article

Distribution, levels, and activation of MEK1 in Alzheimer's disease

scientific article published on 01 July 2003

Disturbance in AMP-activated protein kinase (AMPK) signaling pathway in Alzheimer's disease

Divalent metal transporter, iron, and Parkinson's disease: a pathological relationship

scientific article

Do neurons have a choice in death?

scientific article published on January 2001

Do β-defensins and other antimicrobial peptides play a role in neuroimmune function and neurodegeneration?

scientific article published on 19 April 2012

Down-regulation of aminolevulinate synthase, the rate-limiting enzyme for heme biosynthesis in Alzheimer's disease

scientific article

Drug discovery for neurodegenerative diseases: challenges and novel biochemical targets dedicated to the memory of Mark A. Smith for his inspiring contribution to Alzheimer's disease

scientific article published in January 2011

Drug-Abuse Nanotechnology: Opportunities and Challenges

scientific article published on 31 May 2018

Dysfunctional tubular endoplasmic reticulum constitutes a pathological feature of Alzheimer's disease

scientific article published on December 2015

Dysregulation of leptin signaling in Alzheimer disease: evidence for neuronal leptin resistance

scientific article published on 21 August 2013

Dystrophic neurites infiltrate extracellular neurofibrillary tangles in Alzheimer disease

scientific article published in September 1991

ESCRT-0 dysfunction compromises autophagic degradation of protein aggregates and facilitates ER stress-mediated neurodegeneration via apoptotic and necroptotic pathways.

scientific article published on 26 April 2016

Early AGEing and Alzheimer's

scientific article published in March 1995

Ectopic expression of phospho-Smad2 in Alzheimer's disease: uncoupling of the transforming growth factor-beta pathway?

scientific article published in December 2006

Ectopic localization of FOXO3a protein in Lewy bodies in Lewy body dementia and Parkinson's disease

scientific article published on 23 July 2009

Ectopic localization of phosphorylated histone H3 in Alzheimer's disease: a mitotic catastrophe?

scientific article published on 26 February 2003

Editorial (A New Era for Medicinal Chemistry) ⬇️

scientific article published on 01 January 2012

Editorial [Special Issue in Honor of the 70th Birthday of Dr. Atta-ur-Rahman, FRS]

Editors & Editorial Board

Editors & Editorial Board

Effect of quinones on microtubule polymerization: a link between oxidative stress and cytoskeletal alterations in Alzheimer's disease

scientific article published on 13 December 2004

Effect of the herbicide 4-CPA on human erythrocyte antioxidant enzymes in vitro

scientific article published in January 2001

Effect of the lipid peroxidation product acrolein on tau phosphorylation in neural cells

scientific article published on March 2003

Elastase is associated with the neurofibrillary pathology of Alzheimer disease: a putative link between proteolytic imbalance and oxidative stress ⬇️

scientific article published on January 1, 1996

Electron microscopic localization of Alzheimer neurofibrillary tangle components recognized by an antiserum to paired helical filaments.

scientific article published in March 1986

Elevated expression of a regulator of the G2/M phase of the cell cycle, neuronal CIP-1-associated regulator of cyclin B, in Alzheimer's disease

scientific article

Elevated luteinizing hormone expression colocalizes with neurons vulnerable to Alzheimer's disease pathology

scientific article published in November 2002

Elevation of {beta}-amyloid 1-42 autoantibodies in the blood of amnestic patients with mild cognitive impairment

scientific article published in July 2010

Elongation affinity, activation barrier, and stability of Aβ42 oligomers/fibrils in physiological saline

scientific article published on 17 April 2017

Emerging evidence for the neuroprotective role of alpha-synuclein

scientific article

Enhanced Phosphorylation of Bax and Its Translocation into Mitochondria in the Brains of Individuals Affiliated with Alzheimer's Disease

scientific article published on 16 November 2017

Erythrocyte, plasma, and serum antioxidant activities in untreated toxic multinodular goiter patients

scientific article published in March 2001

Estrogen bows to a new master: the role of gonadotropins in Alzheimer pathogenesis

scientific article

Estrogen receptor-α is localized to neurofibrillary tangles in Alzheimer's disease

scientific article published on 3 February 2016

Estrogen replacement and risk of Alzheimer disease

scientific article published in The Journal of the American Medical Association

Ethanol-fixed, paraffin-embedded tissue imaging: implications for Alzheimer's disease research

scientific article published on 17 August 2020

Ethics review as a catalyst for progress

scientific article published on January 2014

Evaluation of Metabolic and Synaptic Dysfunction Hypotheses of Alzheimer's Disease (AD): A Meta-Analysis of CSF Markers

scientific article published on 21 September 2017

Evidence for Oxidative Damage in the Autistic Brain

article

Evidence for a novel heme-binding protein, HasAh, in Alzheimer disease

scientific article published in January 2000

Evidence for oxidative stress in Pick disease and corticobasal degeneration

scientific article

Evidence for the novel expression of human kallikrein-related peptidase 3, prostate-specific antigen, in the brain.

scientific article published on 20 October 2008

Evidence for the progression through S-phase in the ectopic cell cycle re-entry of neurons in Alzheimer disease

scientific article published on April 2009

Evidence for the role of gonadotropin hormones in the development of Alzheimer disease

scientific article

Evidence for the role of luteinizing hormone in Alzheimer disease

scientific article published on December 2007

Evidence of DNA damage in Alzheimer disease: phosphorylation of histone H2AX in astrocytes

scientific article published on 23 April 2008

Evidence of oxidative stress and in vivo neurotoxicity of beta-amyloid in a transgenic mouse model of Alzheimer's disease: a chronic oxidative paradigm for testing antioxidant therapies in vivo ⬇️

scientific article published on April 1, 1998

Evidence that the beta-amyloid plaques of Alzheimer's disease represent the redox-silencing and entombment of abeta by zinc

scientific article

Expression Profiling of Cytokine, Cholinergic Markers, and Amyloid-β Deposition in the APPSWE/PS1dE9 Mouse Model of Alzheimer's Disease Pathology.

scientific article published in January 2018

Expression of CD74 is increased in neurofibrillary tangles in Alzheimer's disease

scientific article published on 11 September 2008

Expression of growth hormone in the baboon eye.

scientific article

Extracellular neurofibrillary tangles reflect neuronal loss and provide further evidence of extensive protein cross-linking in Alzheimer disease ⬇️

scientific article published on January 1, 1995

Faculty of 1000 evaluation for A copper-binding site in the cytoplasmic domain of BACE1 identifies a possible link to metal homoeostasis and oxidative stress in Alzheimer's disease

scholarly article published 2 August 2007

Faculty of 1000 evaluation for A frameshift deletion in peripherin gene associated with amyotrophic lateral sclerosis

article

Faculty of 1000 evaluation for A new function of microtubule-associated protein tau: involvement in chromosome stability

Faculty of 1000 evaluation for ALS-causing SOD1 mutants generate vascular changes prior to motor neuron degeneration

Faculty of 1000 evaluation for Aberrant neuronal and mitochondrial proteins in hippocampus of transgenic mice overexpressing human Cu/Zn superoxide dismutase 1

Faculty of 1000 evaluation for Abeta immunotherapy leads to clearance of early, but not late, hyperphosphorylated tau aggregates via the proteasome

Faculty of 1000 evaluation for Abeta is targeted to the vasculature in a mouse model of hereditary cerebral hemorrhage with amyloidosis

Faculty of 1000 evaluation for Aging-related increase in oxidative stress correlates with developmental pattern of beta-secretase activity and beta-amyloid plaque formation in transgenic Tg2576 mice with Alzheimer-like pathology

scholarly article published 17 February 2005

Faculty of 1000 evaluation for Alpha-synuclein has structural and functional similarities to small heat shock proteins

Faculty of 1000 evaluation for Alzheimer's amyloid peptides mediate hypoxic up-regulation of L-type Ca2+ channels

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Ferric cycle activity and Alzheimer disease

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Fibrillar Amyloid-β Accumulation Triggers an Inflammatory Mechanism Leading to Hyperphosphorylation of the Carboxyl-Terminal End of Tau Polypeptide in the Hippocampal Formation of the 3×Tg-AD Transgenic Mouse

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Filaments of Lewy bodies contain insoluble cytoskeletal elements ⬇️

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Filaments of Pick's bodies contain altered cytoskeletal elements

scientific article published in June 1987

Flux and metabolite pathway mapping in the aging and Alzheimer's disease hippocampus

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Food Antioxidants and Alzheimer’s Disease

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Foreword (The Largest Unmet Market: Chronic Diseases of Aging)

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Foreword: Apoptotic Mechanisms in Neurodegenerative Diseases

Formation of aberrant phosphotau fibrillar polymers in neural cultured cells

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Free radical damage, iron, and Alzheimer's disease

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From Neurodegeneration to Brain Health: An Integrated Approach.

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From Oxidative Stress to Ageing via Lifestyle, Nutraceuticals, Polypharmacy, and Neuropsychological Factors

From aging to Alzheimer's disease: unveiling "the switch" with the senescence-accelerated mouse model (SAMP8).

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Frontiers in Alzheimer's disease therapeutics

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Functional and Genomic Features of Human Genes Mutated in Neuropsychiatric Disorders

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Functional implications of antiestrogen induction of quinone reductase: inhibition of estrogen-induced deoxyribonucleic acid damage

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Gender differences in Alzheimer disease: the role of luteinizing hormone in disease pathogenesis

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Genetic Risk of Alzheimer's Disease: Three Wishes Now That the Genie is Out of the Bottle

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Genetic evidence for oxidative stress in Alzheimer's disease

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Geometric complexity is increased in in vitro activated platelets

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Getting the iron out: phlebotomy for Alzheimer's disease?

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Gibbs Free-Energy Gradient along the Path of Glucose Transport through Human Glucose Transporter 3

Glial Cell Extracellular Matrix in Alzheimer's Disease

scholarly article published December 1995

Global warming and neurodegenerative disorders: speculations on their linkage

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Glycogen synthase kinase 3: a point of integration in Alzheimer's disease and a therapeutic target?

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Glycoxidation and oxidative stress in Parkinson disease and diffuse Lewy body disease

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Gonadotropins and Alzheimer's disease: the link between estrogen replacement therapy and neuroprotection.

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Gonadotropins: a cohesive gender-based etiology of Alzheimer disease

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Guidelines for the use and interpretation of assays for monitoring autophagy

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Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

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Heme catabolism and heme oxygenase in neurodegenerative disease

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Heme deficiency in Alzheimer's disease: a possible connection to porphyria

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Heme oxygenase-1 is associated with the neurofibrillary pathology of Alzheimer's disease.

scientific article published in July 1994

Heme-a, the heme prosthetic group of cytochrome c oxidase, is increased in Alzheimer's disease

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Hibernation, a Model of Neuroprotection

Hibernation, a model of neuroprotection

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High molecular weight neurofilament proteins are physiological substrates of adduction by the lipid peroxidation product hydroxynonenal

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High-resolution analytical imaging and electron holography of magnetite particles in amyloid cores of Alzheimer's disease

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Hirano bodies contain tau protein

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Histochemical and immunocytochemical approaches to the study of oxidative stress

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Homocysteine and Alzheimer's disease: a modifiable risk?

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How important is oxidative damage? Lessons from Alzheimer's disease

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Human amyloid-derived aßcontains tyrosine cross-linked oligomers

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Hydroxynonenal adducts indicate a role for lipid peroxidation in neocortical and brainstem Lewy bodies in humans

scientific article published in February 2002

Hydroxynonenal generated crosslinking fluorophores accumulate in Alzheimer's disease

scholarly article by Justin C. Shenk et al published July 2009 in Alzheimer's and Dementia

Hydroxynonenal, toxic carbonyls, and Alzheimer disease

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Hydroxynonenal-generated crosslinking fluorophore accumulation in Alzheimer disease reveals a dichotomy of protein turnover

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Hypertension in dialysis patients

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Hypoperfusion, Mitochondria Failure, Oxidative Stress, and Alzheimer Disease

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Hypoxic Preconditioning Averts Sporadic Alzheimer's Disease-Like Phenotype in Rats: A Focus on Mitochondria

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Identification of Inhibitors of CD36-Amyloid Beta Binding as Potential Agents for Alzheimer's Disease

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Ill-fated amyloid-beta vaccine

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Imaging the Alzheimer brain

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Immunoaffinity demonstration that paired helical filaments of Alzheimer disease share epitopes with neurofilaments, MAP2 and tau.

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Immunochemical Properties of Ubiquitin Conjugates in the Paired Helical Filaments of Alzheimer Disease

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Immunochemical demonstration of tropomyosin in the neurofibrillary pathology of Alzheimer's disease.

scientific article published on August 1990

Immunocytochemical evidence that the beta-protein precursor is an integral component of neurofibrillary tangles of Alzheimer's disease

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Immunocytochemical localization of the erythroid glucose transporter: abundance in tissues with barrier functions.

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Immunocytochemical properties of Alzheimer straight filaments

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Immunolocalization of the amyloid precursor protein within the senile plaque.

scientific article published in January 1989

Impaired balance of mitochondrial fission and fusion in Alzheimer's disease

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Impaired mitochondrial biogenesis contributes to mitochondrial dysfunction in Alzheimer's disease

scientific article published on 8 December 2011

In Alzheimer's disease, heme oxygenase is coincident with Alz50, an epitope of tau induced by 4-hydroxy-2-nonenal modification

scientific article published in September 2000

In Memoriam: Mark A. Smith, PhD

In Memoriam: Mark A. Smith, PhD: Neuroscientist and Visionary

In Situ Localization of Nonenzymatic Peroxidase-Like Activity of Tissue-Bound Transition Metals

scholarly article published June 2004

In Situ Oxidative Catalysis by Neurofibrillary Tangles and Senile Plaques in Alzheimer’s Disease

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In Vivo and In Silico Evidence: Hippocampal Cholesterol Metabolism Decreases with Aging and Increases with Alzheimers Disease -- Modeling Brain Aging and Disease

In situ methods for detection and localization of markers of oxidative stress: application in neurodegenerative disorders

scientific article published in January 1999

In vivo visualization of tau deposits in corticobasal syndrome by 18F-THK5351 PET.

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Increase of cdk5 is related to neurofibrillary pathology in progressive supranuclear palsy

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Increased autophagic degradation of mitochondria in Alzheimer disease

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Increased expression of p130 in Alzheimer disease

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Increased expression of the remodeling- and tumorigenic-associated factor osteopontin in pyramidal neurons of the Alzheimer's disease brain

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Increased iron and free radical generation in preclinical Alzheimer disease and mild cognitive impairment

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Increased isoprostane and prostaglandin are prominent in neurons in Alzheimer disease

scientific article published on 22 January 2007

Increased levels of oxidative stress markers detected in the brains of mice devoid of prion protein

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Increased neuronal glucose-6-phosphate dehydrogenase and sulfhydryl levels indicate reductive compensation to oxidative stress in Alzheimer disease

scientific article published in October 1999

Increased oxidative stress involving olfactory neurons in Alzheimer disease

Increased p27, an essential component of cell cycle control, in Alzheimer's disease

scientific article published in April 2003

Increases in luteinizing hormone are associated with declines in cognitive performance

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Incubation with Cu(II) and Zn(II) salts enhances MALDI-TOF mass spectra of amyloid-beta and α-synuclein toward in-vivo analysis

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Indices of metabolic dysfunction and oxidative stress

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Indoleamine 2,3-dioxygenase and 3-hydroxykynurenine modifications are found in the neuropathology of Alzheimer's disease

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Induction of HO-1 and NOS in doppel-expressing mice devoid of PrP: implications for doppel function

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Induction of NADPH cytochrome P450 reductase by the Alzheimer beta-protein. Amyloid as a "foreign body".

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Induction of heme oxygenase-1 mRNA and protein in neocortex and cerebral vessels in Alzheimer's disease

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Inge Grundke-Iqbal: A Legacy of Tau in the Etiology of Alzheimer Disease (1937–2012)

Inhibition of Calpain Protects Against Tauopathy in Transgenic P301S Tau Mice

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Inhibition of mitochondrial fragmentation protects against Alzheimer's disease in rodent model

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Insights into amyloid-beta-induced mitochondrial dysfunction in Alzheimer disease

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Insights into cerebrovascular complications and Alzheimer disease through the selective loss of GRK2 regulation

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Insights into the structural patterns of the antileishmanial activity of bi- and tricyclic N-heterocycles.

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Insulin and Insulin-Sensitizing Drugs in Neurodegeneration: Mitochondria as Therapeutic Targets

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Insulin is a two-edged knife on the brain

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Insulin signaling, diabetes mellitus and risk of Alzheimer disease.

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Insulin-resistant brain state: the culprit in sporadic Alzheimer's disease?

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Interaction of Calcium-Calmodulin in Microtubule Assembly in Vitro

Intrahippocampal amyloid-β (1-40) injections injure medial septal neurons in rats

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Intraneuronal amyloid beta accumulation and oxidative damage to nucleic acids in Alzheimer disease

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Introduction: Imaging in Alzheimer's disease

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Involvement of Maillard reactions in Alzheimer disease

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Involvement of gonadotropins in cognitive function: implications for Alzheimer's disease

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Involvement of oxidative stress in Alzheimer disease

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Iron accumulation in Alzheimer disease is a source of redox-generated free radicals ⬇️

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Iron chelation and nanoparticle target delivery in the development of new multifunctional disease-modifying drugs for Alzheimer's disease.

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Iron homeostasis is maintained in the brain, but not the liver, following mild hypoxia

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Iron: A Pathological Mediator of Alzheimer Disease? ⬇️

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Iron: a pathological mediator of Alzheimer disease?

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Iron: the Redox-active center of oxidative stress in Alzheimer disease

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Iron·ic facts about dementia.

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Is Alzheimer's disease a mitochondrial disorder?

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Is Alzheimers Disease a Myth? When is Disease a Disease?

Is amyloid beta-protein glycated in Alzheimer's disease?

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Is exercise-in-a-bottle likely to proffer new insights into Alzheimer's disease?

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Is increased redox-active iron in Alzheimer disease a failure of the copper-binding protein ceruloplasmin?

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Is interaction of amyloid β-peptides with metals involved in cognitive activity?

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Is nitric oxide a key target in the pathogenesis of brain lesions during the development of Alzheimer's disease?

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Is oxidative damage central to the pathogenesis of Alzheimer disease?

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Is oxidative damage the fundamental pathogenic mechanism of Alzheimer's and other neurodegenerative diseases?

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Is oxidative stress an initiator of mitochondrial failure and vascular hypoperfusion during aging and Alzheimer disease? Present and future

Islet amyloid polypeptide (IAPP): a second amyloid in Alzheimer's disease

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Isotyping the human TOMM40 variable-length polymorphism by gene amplification and restriction digest

scientific article published in December 2012

JKK1, an upstream activator of JNK/SAPK, is activated in Alzheimer's disease

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Journal of Huntington's Disease – The Family Gets Bigger

Journal of Parkinson's Disease – Birth of JAD's New Sister

scholarly article by George Perry published 14 June 2011 in Journal of Alzheimer's Disease

LRRK2 in Parkinson's disease and dementia with Lewy bodies

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LRRK2 protein is a component of lewy bodies

LRRK2 regulates mitochondrial dynamics and function through direct interaction with DLP1

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La función del estrés oxidativo en la patogénesis de la enfermedad de Alzheimer

Labeling of cerebral amyloid beta deposits in vivo using intranasal basic fibroblast growth factor and serum amyloid P component in mice

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Larry Sparks: Innovator and Iconoclast

Laser-Induced In-Source Decay Applied to the Determination of Amyloid-Beta in Alzheimer's Brains

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Late phase cell cycle proteins in Alzheimer’s disease: a possible target for therapy?

Latrepirdine: molecular mechanisms underlying potential therapeutic roles in Alzheimer's and other neurodegenerative diseases

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Launch of ‘Atlas Journal of Medical and Biological Sciences’

Learning invariant object recognition in the visual system with continuous transformations

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Leptin: a novel therapeutic strategy for Alzheimer's disease

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Lester (Skip) Binder (1949-2013): in the beginning was tau.

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Leucine-rich repeat kinase 2 colocalizes with alpha-synuclein in Parkinson's disease, but not tau-containing deposits in tauopathies

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Levuglandin E2-protein adducts in human plasma and vasculature

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Lewy bodies contain epitopes both shared and distinct from Alzheimer neurofibrillary tangles

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Lipid peroxidation and 4-hydroxy-2-nonenal formation by copper ion bound to amyloid-beta peptide

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Lipid peroxidation markers are associated with granulovacuolar degeneration but not lipofuscin formation

Lipoic acid and N-acetyl cysteine decrease mitochondrial-related oxidative stress in Alzheimer disease patient fibroblasts.

scientific article published on September 2007

Lipoic acid and N-acetyl cysteine protect against mitochondrial-related oxidative stress in fibroblasts from Alzheimer disease patients

Lithium as a Treatment for Alzheimer's Disease: The Systems Pharmacology Perspective

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Looking at Alzheimer‘s disease from a different angle

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Loss of awareness of hyposmia is associated with mild cognitive impairment in Parkinson's disease

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Low Dose Pioglitazone Attenuates Oxidative Damage in Early Alzheimer's Disease by Binding mitoNEET

scholarly article published January 2015

Low plasma leptin in cognitively impaired ADNI subjects: gender differences and diagnostic and therapeutic potential

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Luteinizing hormone modulates cognition and amyloid-beta deposition in Alzheimer APP transgenic mice

scientific article published on 13 February 2006

Luteinizing hormone, a reproductive regulator that modulates the processing of amyloid-beta precursor protein and amyloid-beta deposition

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MAPK signalling pathway in cancers: Olive products as cancer preventive and therapeutic agents

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MAPKs are differentially modulated in arctic ground squirrels during hibernation

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MSDC-0160 and MSDC-0602 Binding with Human Mitochondrial Pyruvate Carrier (MPC) 1 and 2 Heterodimer

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Magnitude and Kinetics of CD8+ T Cell Activation during Hyperacute HIV Infection Impact Viral Set Point

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Malignant glioma progression and nitric oxide

scientific article published on 12 September 2006

Mark A. Smith

Mark A. Smith, 1965-2010: consummate student of pathogenesis

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Mark A. Smith, PhD: Renegade Scientist and Visionary

Mark A. Smith: neurocytochemistry innovator

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Mark A. Smith: the scientist, the man.

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Mark Anthony Smith (1965-2010): Visionary, Alzheimer researcher, and editor-in-chief of the Journal of Alzheimer's Disease

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Mark Smith: Pioneer of Alzheimer Disease Research

Markers of oxidative damage to lipids, nucleic acids and proteins and antioxidant enzymes activities in Alzheimer's disease brain: A meta-analysis in human pathological specimens.

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Mathematical modeling of microtubule dynamics: insights into physiology and disease

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Mechanisms by which metals promote events connected to neurodegenerative diseases

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Mechanisms of DNA Damage and Repair in Alzheimer Disease

Mechanisms of neurotoxicity associated with amyloid beta deposition and the role of free radicals in the pathogenesis of Alzheimer's disease: a critical appraisal

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Melanin production through novel processing of proopiomelanocortin in the extracellular compartment of the auricular skin of C57BL/6 mice after UV-irradiation

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Melatonin acts as antioxidant and pro-oxidant in an organotypic slice culture model of Alzheimer's disease

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Melatonin exhibits antioxidant properties in a mouse brain slice model of excitotoxicity

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Melatonin increases survival and inhibits oxidative and amyloid pathology in a transgenic model of Alzheimer's disease

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Melatonin increases survival and inhibits oxidative and amyloid pathology in a transgenic model of Alzheimer's disease

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Melatonin reduces interleukin secretion in amyloid-beta stressed mouse brain slices

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Memantine: "hypothesis testing" not "disease modifying" in Alzheimer's disease

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Menopause, estrogen, and gonadotropins in Alzheimer's disease

scientific article published on January 2008

Meta-analysis of Telomere Length in Alzheimer's Disease

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Metabolic, metallic, and mitotic sources of oxidative stress in Alzheimer disease

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Metal Homeostasis and Its Relation to Oxidative Stress in Alzheimer’s Disease

Metal binding and oxidation of amyloid-beta within isolated senile plaque cores: Raman microscopic evidence

scientific article published in March 2003

Metal chelators coupled with nanoparticles as potential therapeutic agents for Alzheimer's disease

scientific article published on June 2009

Metal ions and oxidative protein modification in neurological disease.

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Metals and oxidative homeostasis in Alzheimer's disease

scholarly article by George Perry et al published July 2002 in Drug Development Research

Methemoglobin catabolism and Alzheimer's disease

scholarly article by Lucijan Mohorovic et al published July 2013 in Alzheimer's and Dementia

Methemoglobinemia—A biomarker and a link to ferric iron accumulation in Alzheimer’s disease

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Methods in Molecular Medicine, Vol. 32 Alzheimer's Disease: Methods and Protocols

scholarly article by George Perry & Mark A. Smith published 2000 in Journal of Molecular Neuroscience

Mexico City normal weight children exposed to high concentrations of ambient PM2.5 show high blood leptin and endothelin-1, vitamin D deficiency, and food reward hormone dysregulation versus low pollution controls. Relevance for obesity and Alzheime

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Mfn2 ablation causes an oxidative stress response and eventual neuronal death in the hippocampus and cortex.

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Microbes and Alzheimer's Disease

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Microfilament Involvement in Hirano Body Formation

Microglia are associated with the extracellular neurofibrillary tangles of Alzheimer disease

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Microglial activation and amyloid-beta clearance induced by exogenous heat-shock proteins

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Microtubule Reduction in Alzheimer's Disease and Aging Is Independent of τ Filament Formation ⬇️

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Miro1 deficiency in amyotrophic lateral sclerosis

scientific article published on 26 May 2015

Mitochondria DNA deletions in atherosclerotic hypoperfused brain microvessels as a primary target for the development of Alzheimer's disease

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Mitochondria Directed Oxidative Stress and Metal Abnormalities at the Center of Alzheimer’s Disease

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Mitochondria and Neurodegenerative Diseases

Mitochondria and vascular lesions as a central target for the development of Alzheimer's disease and Alzheimer disease-like pathology in transgenic mice

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Mitochondria as a primary target for vascular hypoperfusion and oxidative stress in Alzheimer's disease

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Mitochondria dysfunction in the pathogenesis of Alzheimer's disease: recent advances

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Mitochondria: a therapeutic target in neurodegeneration

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Mitochondria: the missing link between preconditioning and neuroprotection

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Mitochondrial DNA oxidative damage and repair in aging and Alzheimer's disease

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Mitochondrial Drugs for Alzheimer Disease

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Mitochondrial abnormalities and oxidative imbalance in Alzheimer disease.

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Mitochondrial abnormalities and oxidative imbalance in neurodegenerative disease

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Mitochondrial abnormalities in Alzheimer disease

Mitochondrial abnormalities in Alzheimer's disease.

scientific article published in May 2001

Mitochondrial abnormalities in a streptozotocin-induced rat model of sporadic Alzheimer's disease

scientific article published in May 2013

Mitochondrial dynamic abnormalities in amyotrophic lateral sclerosis

scientific article published on 29 July 2015

Mitochondrial dynamics in Alzheimer's disease: opportunities for future treatment strategies

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Mitochondrial dysfunction is a trigger of Alzheimer's disease pathophysiology

scientific article published on 21 October 2009

Mitochondrial failures in Alzheimer's disease

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Mitochondrial importance in Alzheimer's, Huntington's and Parkinson's diseases

scientific article published on January 2012

Mitochondrial preconditioning: a potential neuroprotective strategy

scientific article published on 26 August 2010

Mitochondrial traffic jams in Alzheimer's disease - pinpointing the roadblocks

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Mitofusin 2 Regulates Axonal Transport of Calpastatin to Prevent Neuromuscular Synaptic Elimination in Skeletal Muscles

scientific article published on 12 July 2018

Mitogen- and stress-activated protein kinase 1: convergence of the ERK and p38 pathways in Alzheimer's disease

scientific article published in February 2005

Mitotic and gender parallels in Alzheimer disease: therapeutic opportunities

scientific article published in August 2004

Modeling cholesterol metabolism by gene expression profiling in the hippocampus

scientific article published on 30 March 2011

Modification of amyloid-β1-42 fibril structure by methionine-35 oxidation

scientific article published in January 2013

Modification of hippocampal excitability in brain slices pretreated with a low nanomolar concentration of Zn2+.

scientific article published on 13 August 2015

Modulation of Parkinson's Disease Associated Protein Rescues Alzheimer's Disease Degeneration

scientific article published on 12 October 2016

Molecular Mapping Alzheimer's Disease: MALDI Imaging of Formalin-fixed, Paraffin-embedded Human Hippocampal Tissue

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Molecular Pathways in Normal Aging and Neurodegeneration: Mechanisms and Therapeutics

scientific article published on 01 January 2017

Molecular neuropathogenesis of Alzheimer's disease: an interaction model stressing the central role of oxidative stress

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Molecular pathogenesis of Alzheimer's disease: reductionist versus expansionist approaches

scientific article published on 26 March 2009

NMR studies of zinc, copper, and iron binding to histidine, the principal metal ion complexing site of amyloid-beta peptide

scientific article published in January 2010

Nanoparticle and iron chelators as a potential novel Alzheimer therapy

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Nanoparticle and other metal chelation therapeutics in Alzheimer disease

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Nanoparticle delivery of transition-metal chelators to the brain: Oxidative stress will never see it coming!

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Nanoparticle iron chelators: a new therapeutic approach in Alzheimer disease and other neurologic disorders associated with trace metal imbalance

scientific article published on 21 August 2006

Nanoparticle-chelator conjugates as inhibitors of amyloid-beta aggregation and neurotoxicity: a novel therapeutic approach for Alzheimer disease

scientific article published on 25 March 2009

Nanoparticle-iron Chelator Conjugates as Multifunctional Disease-modifying Drugs for Prevention and Treatment of Alzheimer’s Disease

Nanoparticles for the Treatment of Alzheimer's Disease: Theoretical Rationale, Present Status and Future Perspectives

scholarly article published 15 September 2007

Nanoscale synchrotron X-ray speciation of iron and calcium compounds in amyloid plaque cores from Alzheimer's disease subjects.

scientific article published on 24 April 2018

National Dementia BioBank: A Strategy for the Diagnosis and Study of Neurodegenerative Diseases in México

scientific article published on 15 June 2020

Natural Oxidant Balance in Parkinson Disease

scholarly article by George Perry et al published 1 December 2009 in Archives of Neurology

Neurochemistry of dementia: establishing the links

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Neurodegeneration Methods and Protocols. Jean Harry , Hugh A. Tilson

Neurodegenerative diseases: mechanisms and therapies

scientific article published in January 2006

Neurodegenerative processes in Alzheimer’s disease: an overview of pathogenesis with strategic biomarker potential

Neurofibrillary Tangle Formation as a Protective Response to Oxidative Stress in Alzheimer’s Disease

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Neurofilament proteins in neurodegenerative diseases

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Neurofilamentopathy in neurodegenerative diseases

scientific article published on 26 August 2011

Neurofilaments are the major neuronal target of hydroxynonenal-mediated protein cross-links ⬇️

scientific article published on May 10, 2013

Neurogenesis in Alzheimer’s Disease

Neurogenesis in Human Hippocampus: Implications for Alzheimer Disease Pathogenesis

Neuroinflammation, hyperphosphorylated tau, diffuse amyloid plaques, and down-regulation of the cellular prion protein in air pollution exposed children and young adults

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Neuroinflammatory Environments Promote Amyloid-β Deposition and Posttranslational Modification

Neuroinflammatory Responses in the Alzheimer's Disease Brain Promote the Oxidative Post-translational Modification of Amyloid Deposits

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Neuronal Oxidative Stress is a Common Feature of Alzheimer’s and Parkinson’s Diseases

scholarly article by George Perry & Mark A. Smith published 1998 in Advances in behavioral biology

Neuronal RNA oxidation in Alzheimer's disease and Down's syndrome

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Neuronal RNA oxidation is a prominent feature of dementia with Lewy bodies

scientific article published in November 2002

Neuronal RNA oxidation is a prominent feature of familial Alzheimer's disease

scientific article published in October 2004

Neuronal Survival and Death in Alzheimer Disease

Neuronal and microglial involvement in beta-amyloid protein deposition in Alzheimer's disease

scientific article published on August 1990

Neuronal binucleation in Alzheimer disease hippocampus

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Neuronal death and survival under oxidative stress in Alzheimer and Parkinson diseases

scientific article published on December 2007

Neuronal failure in Alzheimer's disease: a view through the oxidative stress looking-glass

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Neuronal leptin resistance in Alzheimer's disease

scholarly article by David Bonda et al published July 2013 in Alzheimer's and Dementia

Neuronal mitochondrial amelioration by feeding acetyl-L-carnitine and lipoic acid to aged rats

scientific article published on 28 March 2008

Neuronal oxidative stress precedes amyloid-beta deposition in Down syndrome

scientific article published on 01 November 2000

Neuropathology and treatment of Alzheimer disease: did we lose the forest for the trees?

scientific article published on May 2007

Neuropathology in Alzheimer's disease: awaking from a hundred-year-old dream

scientific article published on 3 May 2006

Neuropathology in Consecutive Forensic Consultation Cases with a History of Remote Traumatic Brain Injury

scientific article published on 01 January 2019

Neuropathology of Alzheimer disease: pathognomonic but not pathogenic

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Neuropil threads of Alzheimer's disease show a marked alteration of the normal cytoskeleton

scientific article published in June 1991

Neuroprotective and Antioxidant Effect of Ginkgo biloba Extract Against AD and Other Neurological Disorders

scientific article published on 01 July 2019

Neuroprotective effect of cocoa flavonoids on in vitro oxidative stress

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Neuroprotective effect of cocoa flavonoids on in vitro oxidative stress

Neuroprotective properties of Bcl-w in Alzheimer disease

scientific article

Neuropsychiatric Disturbances and Diabetes Mellitus: The Role of Oxidative Stress

scientific article published on 04 July 2019

Neuropsychiatric genetics in developing countries: Current challenges

scientific article published in December 2014

Neurotoxic dopamine quinone facilitates the assembly of tau into fibrillar polymers

scientific article published in October 2005

New insights into the mechanisms of mitochondrial preconditioning-triggered neuroprotection

scientific article published on January 2011

No Evidence of Increased Chronic Traumatic Encephalopathy Pathology or Neurodegenerative Proteinopathy in Former Military Service Members: A Preliminary Study

scientific article published on 01 January 2019

Non-enzymatically glycated tau in Alzheimer's disease induces neuronal oxidant stress resulting in cytokine gene expression and release of amyloid beta-peptide

scientific article published in July 1995

Nonestrogen-based hormonal therapies for Alzheimer’s disease

Novel therapeutics for Alzheimer's disease: an update

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Nuclear and mitochondrial DNA oxidation in Alzheimer's disease

scientific article published on 23 January 2012

Nuclear microscopy of diffuse plaques in the brains of transgenic mice

Nucleic acid oxidation in Alzheimer disease

scientific article published on 18 January 2008

Nucleic acid oxidative damage in Alzheimer's disease-explained by the hepcidin-ferroportin neuronal iron overload hypothesis?

scientific article published on 7 June 2016

Nutrients and Food Constituents in Cognitive Decline and Neurodegenerative Disease

Nutritional Antioxidants, Vitamins, Cognition, and Neurodegenerative Disease

Nutritional supplements and dementia

scientific article published on 20 January 2017

O2-04-07 Elevated expression of a regulator of the G2/M phase of the cell cycle, neuronal CIP-1 associated regulator of cyclin B, in Alzheimer disease

O3-04-07 Vascular and metabolic failure in Alzheimer disease

Ontogeny of the erythroid/HepG2-type glucose transporter (GLUT-1) in the rat nervous system

scientific article published in March 1993

Overexpression of GRK2 in Alzheimer disease and in a chronic hypoperfusion rat model is an early marker of brain mitochondrial lesions

scientific article published in August 2006

Overexpression of heme oxygenase in neuronal cells, the possible interaction with Tau

scientific article published in Journal of Biological Chemistry

Overview of Alzheimer's Disease and Some Therapeutic Approaches Targeting Aβ by Using Several Synthetic and Herbal Compounds

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Oxidative Adaptation in Aging and Alzheimer’s Disease

Oxidative Damage and Antioxidant Responses in Alzheimer's Disease

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Oxidative RNA damage and neurodegeneration

scientific article published on January 2007

Oxidative Stress Induces Senescence in Cultured RPE Cells

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Oxidative Stress Mechanisms and Potential Therapeutic Modalities in Alzheimer Disease

Oxidative Stress Signaling in Alzheimers Disease

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Oxidative Stress and Alzheimer Disease: Mechanisms and Therapeutic Opportunities

Oxidative Stress and Balance in Neurodegenerative Diseases

Oxidative Stress and Neurodegeneration: An Inevitable Consequence of Aging? Implications for Therapy

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Oxidative Stress and its Implications for Future Treatments and Management of Alzheimer Disease

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Oxidative Stress in Alzheimer Disease: The Earliest Cytological and Biochemical Feature

Oxidative Stress in Alzheimer’s Disease: A Critical Appraisal of the Causes and the Consequences

Oxidative Stress in Parkinson`s Disease

scholarly article by Avi L. Friedlich et al published 20 May 2009 in The open pathology journal

Oxidative damage and Alzheimer's disease: are antioxidant therapies useful?

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Oxidative damage in Alzheimer's

scientific article published in July 1996

Oxidative damage in Alzheimer's disease: the metabolic dimension

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Oxidative damage in cultured human olfactory neurons from Alzheimer's disease patients

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Oxidative damage in the olfactory system in Alzheimer's disease

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Oxidative damage is the earliest event in Alzheimer disease

scientific article published in August 2001

Oxidative damage to RNA in aging and neurodegenerative disorders

scientific article published on 06 June 2012

Oxidative damage to RNA in neurodegenerative diseases

scientific article published in January 2006

Oxidative damage to nucleic acids in human prion disease

scientific article published in April 2002

Oxidative imbalance in Alzheimer's disease

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Oxidative posttranslational modifications in Alzheimer disease. A possible pathogenic role in the formation of senile plaques and neurofibrillary tangles

scientific article published on May 1996

Oxidative stress activates a positive feedback between the gamma- and beta-secretase cleavages of the beta-amyloid precursor protein ⬇️

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Oxidative stress and mitochondrial dysfunction in Alzheimer's disease

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Oxidative stress and neurodegeneration

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Oxidative stress and neuronal adaptation in Alzheimer disease: the role of SAPK pathways

scientific article published on October 2003

Oxidative stress and neurotoxicity

scientific article published on 04 December 2007

Oxidative stress and predominant Abeta42(43) deposition in myopathies with rimmed vacuoles

scientific article published on 5 March 2003

Oxidative stress and redox-active iron in Alzheimer's disease

scientific article published on March 2004

Oxidative stress in Alzheimer disease: a possibility for prevention

scientific article published on 13 April 2010

Oxidative stress in Alzheimer's disease

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Oxidative stress in blood in Alzheimer's disease and mild cognitive impairment: a meta-analysis

scientific article published on 15 July 2013

Oxidative stress in diabetes and Alzheimer's disease

scientific article published on January 2009

Oxidative stress increases expression and activity of BACE in NT2 neurons

scientific article published in August 2002

Oxidative stress is an early event in hydrostatic pressure induced retinal ganglion cell damage

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Oxidative stress mechanisms and potential therapeutics in Alzheimer disease

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Oxidative stress signalling in Alzheimer's disease

scientific article published on March 2004

Oxidative stress, antioxidants, and Alzheimer disease

scientific article

Oxidative stress: the old enemy in Alzheimer's disease pathophysiology

scientific article

P1-266 The critical role of the ERK pathway in the pathogenesis of Alzheimer's disease

scholarly article by Xiongwei Zhu et al published July 2004 in Neurobiology of Aging

P1-286 Glycogen synthase kinase-3β activity is regulated by products of lipid peroxidation: relevance to Alzheimer disease

P1-351: A novel approach to diagnosis: Antigen-antibody disassociation in Alzheimer's disease

scholarly article by Mark A. Smith et al published July 2008 in Alzheimer's and Dementia

P1-369 Modulation of cognition and amyloid load in the aged SWAβPP transgenic mouse by luprolide acetate, a GNRH agonist: targeting luteinizing hormone as a novel treatment for AD

P2-003 Cholesterol feeding enhances cerebral amyloid beta pathology in beagles

scholarly article by Robert P. Friedland et al published July 2004 in Neurobiology of Aging

P3-219 Acetylation: a novel posttranslational modification in Alzheimer disease

P3-275 Phosphorylation dependent control of oxidative modification in Alzheimer disease

P3-296

P3-306 Differential expression of metabotrophic glutamate receptors (MGlurs) in Alzheimer disease

P3-317: Failure in the control of cell cycle causes neurodegeneration

P3-375

P38 activation mediates amyloid-beta cytotoxicity

scientific article published on June 2005

P4-162

P4-166: Overexpression of amyloid precursor protein causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins

P4-171: Cerebral hypoperfusion-induced oxidative stress and mitochondrial failure as initiators of aging and Alzheimer's disease pathology

scholarly article by Gjumrakch Aliev et al published July 2008 in Alzheimer's and Dementia

P4-242 Oxidative damage in ferritin-induced neurodegeneration

P4-250 Redox-active iron oxidizes ribosomal RNa in neurons vulnerable to Alzheimer's disease

scholarly article by Kazuhiro Honda et al published July 2004 in Neurobiology of Aging

PARK2 enhancement is able to compensate mitophagy alterations found in sporadic Alzheimer's disease.

scientific article published on 31 December 2015

Paired helical filaments from Alzheimer disease patients contain cytoskeletal components

scientific article published on June 1985

Paraffin-embedded tissue (PET) blot method: application to Alzheimer disease

scientific article

Parallels between major depressive disorder and Alzheimer's disease: role of oxidative stress and genetic vulnerability

scientific article

Parkinson's disease is associated with oxidative damage to cytoplasmic DNA and RNA in substantia nigra neurons

scientific article published on May 1999

Pathobiology of familial hypercholesterolemic atherosclerosis.

scientific article

Pathogenesis and disease-modifying therapy in Alzheimer's disease: the flat line of progress

scientific article published on 16 October 2012

Pathological phenotype in familial neurodegenerative disease: implications for families and therapeutic constructs

Pathology's new role: defining disease process and protective responses.

scientific article published in January 2008

Pathomechanisms of TDP-43 in neurodegeneration

scientific article published on 27 February 2018

Perspectives on the amyloid-beta cascade hypothesis

scientific article published on April 2004

Pharmaceutical Regulation: Crossroad of Opportunity as the Distinction between Food and Drugs Blurs

Phospho-Tau Protein Expression in the Cell Cycle of SH-SY5Y Neuroblastoma Cells: A Morphological Study

scientific article published on 01 January 2019

Phosphorylated tau: toxic, protective, or none of the above

scientific article published on August 2008

Phosphorylation of neurofilaments is altered in amyotrophic lateral sclerosis

scientific article

Phosphorylation of tau protein as the link between oxidative stress, mitochondrial dysfunction, and connectivity failure: implications for Alzheimer's disease

scientific article published on 10 July 2013

Phosphorylation of tau protein at sites Ser(396-404) is one of the earliest events in Alzheimer's disease and Down syndrome

scientific article published in February 2014

Phosphorylation of tau protein correlates with changes in hippocampal theta oscillations and reduces hippocampal excitability in Alzheimer's model

scientific article published on 9 April 2018

Phosphorylation, Microtubule Binding and Aggregation of Tau Protein in Alzheimer's Disease

scholarly article

Physiological regulation of tau phosphorylation during hibernation

scientific article published on June 2008

Plaques and tangles: Birthmarks of the aging soul

scholarly article by George Perry & Rudy Castellani published April 2014 in Biochemical Pharmacology

Plasma membrane fragility in dystrophic neurites in senile plaques of Alzheimer's disease: an index of oxidative stress

scientific article published in January 1996

Polyphenols in Alzheimer's Disease and in the Gut-Brain Axis

scientific article published on 31 January 2020

Possible involvement of ER chaperone Grp78 on reduced formation of amyloid-beta deposits

scientific article published in November 2002

Possible involvement of Wiskott-Aldrich syndrome protein family in aberrant neuronal sprouting in Alzheimer's disease

scientific article

Possible protective mechanisms of heme oxygenase-1 in the brain

scientific article published in November 2002

Posttranslational modifications of α-tubulin in alzheimer disease

scientific article

Potential role of iron in a Mediterranean-style diet

scientific article published on 01 October 2010

Precision pharmacology for Alzheimer's disease

scientific article published on 16 February 2018

Predicting the failure of amyloid-beta vaccine

scientific article published in May 2002

Preface

Preface

Preface. Alzheimer's disease: advances for a new century.

scientific article published in January 2013

Prefrontal white matter pathology in air pollution exposed Mexico City young urbanites and their potential impact on neurovascular unit dysfunction and the development of Alzheimer's disease

scientific article published on 29 January 2016

Presenilin mutation: a deadly first hit in Alzheimer disease. A commentary on "aging sensitizes towards ROS formation and lipid peroxidation in PS1M146L transgenic mice".

scientific article published on 19 January 2006

Presenilin mutations impair mitochondrial dynamics in neurons

Preventative effect of mitochondrial antioxidants in apoe deficiency mouse model of brain hypoperfusion

Prevention and treatment of Alzheimer disease and aging: antioxidants

scientific article published on February 2007

Preventive Effect of 3,5-dihydroxy-4-methoxybenzyl Alcohol (DHMBA) and Zinc, Components of the Pacific Oyster Crassostrea gigas, on Glutamatergic Neuron Activity in the Hippocampus

scientific article published on December 2015

Prion disease and Alzheimer's disease: pathogenic overlap

scientific article

Prion protein is ubiquitinated after developing protease resistance in the brains of scrapie-infected mice

scientific article published in May 2004

Promise from the Sea.

scientific article published on 9 October 2016

Prospects for Antioxidant Therapy in Mild Cognitive Impairment and Alzheimer's Disease

scholarly article published 2007

Prospects for noninvasive imaging of brain amyloid beta in Alzheimer's disease

scientific article published in April 2000

Prospects on the origin of Alzheimer's disease.

scientific article published in January 2010

Protein Misfolding in Alzheimer's Disease

scholarly article published 3 December 2007

Protein disulfide isomerase in Alzheimer disease

scientific article published in January 2000

Proteolytic cleavage of polymeric tau protein by caspase-3: implications for Alzheimer disease.

scientific article

Putative Gonadotropin-Releasing Hormone Agonist Therapy and Dementia: An Application of Medicare Hospitalization Claims Data

scientific article published on 01 January 2018

Quantitative solubilization and analysis of insoluble paired helical filaments from Alzheimer disease

scientific article published in April 1996

Quinone reductase (NQO1), a sensitive redox indicator, is increased in Alzheimer's disease

scientific article published on 01 January 1999

R-_-Lipoic Acid as a Potent Agent of Mitochondrial Protectionin Alzheimer’s Disease

RNA Oxidation in Alzheimer and Parkinson Diseases

scholarly article by AKIHIKO NUNOMURA et al published January 1999 in Rejuvenation Research

RNA oxidation in Alzheimer disease and related neurodegenerative disorders

scientific article published on 07 March 2009

RNA oxidation is a prominent feature of vulnerable neurons in Alzheimer's disease.

scientific article published in March 1999

Rab10 Phosphorylation is a Prominent Pathological Feature in Alzheimer's Disease

scientific article published on 16 March 2018

Radical AGEing in Alzheimer's disease

scientific article published on April 1995

Raúl Mena: 1953-2014.

scientific article published in January 2015

Reactive Oxygen Species Mediate Cellular Damage in Alzheimer Disease.

scientific article published in March 1998

Reactive oxygen: its sources and significance in Alzheimer disease.

scientific article

Reanimating basal forebrain cholinergic neurons in electrophysiology biosimulations using COPASI software

Redox Active Iron at the Center of Oxidative Stress in Alzheimer Disease

article published in 2005

Redox active iron accumulation in aceruloplasminemia

scientific article published on 15 February 2008

Redox metals and neurodegenerative disease

scientific article

Redox metals and oxidative abnormalities in human prion diseases

scientific article published on 11 August 2005

Redox-active iron mediates amyloid-beta toxicity

scientific article

Reduction of inclusion body pathology in ApoE-deficient mice fed a combination of antioxidants

scientific article published in April 2003

Reexamining Alzheimer's disease: evidence for a protective role for amyloid-beta protein precursor and amyloid-beta

scientific article

Regulation of extracellular Zn(2+) homeostasis in the hippocampus as a therapeutic target for Alzheimer's disease

scientific article published on 27 March 2015

Regulation of glycogen synthase kinase-3beta by products of lipid peroxidation in human neuroblastoma cells

scientific article published on June 2004

Retinoblastoma protein phosphorylation at multiple sites is associated with neurofibrillary pathology in Alzheimer disease.

scientific article published on January 2008

Retinoic acid isomers protect hippocampal neurons from amyloid-beta induced neurodegeneration

scientific article published in January 2005

Revisiting protein aggregation as pathogenic in sporadic Parkinson and Alzheimer diseases

scientific article published on 01 February 2019

Revolution of Alzheimer Precision Neurology Passageway of Systems Biology and Neurophysiology

scientific article published on 16 March 2018

Ribosomal RNA in Alzheimer disease is oxidized by bound redox-active iron

scientific article

Rimmed vacuoles of inclusion body myositis and oculopharyngeal muscular dystrophy contain amyloid precursor protein and lysosomal markers

scientific article published in February 1993

Role of Heme Catabolism in Neurodegenerative Diseases

Role of Oxidative Insult and Neuronal Survival in Alzheimer’s and Parkinson’s Diseases

scholarly article

Role of cytokeratin intermediate filaments in transhepatic transport and canalicular secretion

article

Role of high mobility group protein-1 (HMG1) in amyloid-beta homeostasis

scientific article published in February 2003

Role of metal dyshomeostasis in Alzheimer's disease

scientific article

Role of mitochondrial dysfunction in Alzheimer's disease

scientific article

Role of mitochondrial-mediated signaling pathways in Alzheimer disease and hypoxia

scientific article published on October 2009

Role of oxidative stress in frontotemporal dementia

scientific article

Role of the antioxidant ascorbate in hibernation and warming from hibernation

scientific article

Role of vascular hypoperfusion-induced oxidative stress and mitochondria failure in the pathogenesis of Azheimer disease

scientific article published on January 2003

Rosmarinic acid prevents fibrillization and diminishes vibrational modes associated to β sheet in tau protein linked to Alzheimer's disease

scientific article published in December 2017

S4-02-01 Alzheimer disease: the two hit hypothesis

Selective presence of ubiquitin in intracellular inclusions

scientific article

Selenoprotein S Reduces Endoplasmic Reticulum Stress-Induced Phosphorylation of Tau: Potential Role in Selenate Mitigation of Tau Pathology.

scientific article published on 11 October 2016

Senile plaque composition and posttranslational modification of amyloid-beta peptide and associated proteins

scientific article

Senile plaque neurites in Alzheimer disease accumulate amyloid precursor protein ⬇️

scientific article published on September 1, 1991

Senile plaques in cerebral amyloid angiopathy show accumulation of amyloid precursor protein without cytoskeletal abnormalities ⬇️

scientific article published on October 16, 1992

Sequestration of p27 within the cytoplasm of cardiac myocytes in chronic ischemic heart disease: pathogenic implications for ischemic cardiomyopathy

scientific article published on March 2006

Serial reconstruction of β-protein amyloid plaques: relationship to microvessels and size distribution ⬇️

scientific article published on October 2, 1992

Serine protease inhibitor antithrombin III and its messenger RNA in the pathogenesis of Alzheimer's disease.

scientific article

Sex differences in functional and molecular neuroimaging biomarkers of Alzheimer's disease in cognitively normal older adults with subjective memory complaints

scientific article published on 07 July 2018

Signal Transduction in Alzheimer’s Disease

article published in 2002

Signal transduction cascades associated with oxidative stress in Alzheimer's disease

scientific article published on May 2007

Signaling effect of amyloid-beta(42) on the processing of AbetaPP

scientific article

Simultaneous onset of Alzheimer's disease in a husband and wife in their mid-fifties: what do we really know about environmental factors? ⬇️

scientific article

Single-channel permeability and glycerol affinity of human aquaglyceroporin AQP3

scientific article published on 17 January 2019

Slower Dynamics and Aged Mitochondria in Sporadic Alzheimer's Disease

scientific article published on 19 October 2017

Soluble derivatives of the beta amyloid protein precursor of Alzheimer's disease are labeled by antisera to the beta amyloid protein

scientific article published in November 1989

Sources and mechanisms of cytoplasmic oxidative damage in Alzheimer's disease.

scientific article published on January 2004

Specific reaction of Met 35 in amyloid beta peptide with hypochlorous acid

scientific article published in July 2010

Staying connected: synapses in Alzheimer disease

scientific article

Stem cell niches as clinical targets: the future of anti-ischemic therapy?

scientific article

Steroidogenic acute regulatory protein (StAR): evidence of gonadotropin-induced steroidogenesis in Alzheimer disease

scientific article

Striation is the characteristic neuritic abnormality in Alzheimer disease

scientific article published in December 1998

Structures and free energy landscapes of aqueous zinc(II)-bound amyloid-β(1-40) and zinc(II)-bound amyloid-β(1-42) with dynamics.

scientific article published on 07 June 2012

Subcellular localization of amyloid precursor protein in senile plaques of Alzheimer's disease ⬇️

scientific article published on April 1, 1992

Subgroup differences in 'brain-type' transferrin and α-synuclein in Parkinson's disease and multiple system atrophy

scientific article published on 11 March 2016

Sublethal RNA oxidation as a mechanism for neurodegenerative disease

scientific article published on 20 May 2008

Systemic increase of oxidative nucleic acid damage in Parkinson's disease and multiple system atrophy

scientific article published in March 2002

TDP-43 inhibitory peptide alleviates neurodegeneration and memory loss in an APP transgenic mouse model for Alzheimer's disease

scientific article published on 31 October 2019

TDP-43 proteinopathy and mitochondrial abnormalities in neurodegeneration

scientific article published on 21 August 2019

TMEM230 Accumulation in Granulovacuolar Degeneration Bodies and Dystrophic Neurites of Alzheimer's Disease

scientific article published on 17 May 2017

Tackling Alzheimer’s Disease by Targeting Oxidative Stress and Mitochondria

Tackling the Elusive Challenges Relevant to Conquering the 100-Plus Year Old Problem of Alzheimer's Disease

scholarly article by Luis V. Colom et al published 1 January 2013 in Current Alzheimer Research

Tackling the elusive challenges relevant to conquering the 100-plus year old problem of Alzheimer's disease

scientific article published on January 2013

Targeting gonadotropins: an alternative option for Alzheimer disease treatment

scientific article

Tau Biology, Tauopathy, Traumatic Brain Injury, and Diagnostic Challenges

Tau modifiers as therapeutic targets for Alzheimer's disease

scientific article

Tau phosphorylation and assembly.

scientific article published on January 2004

Tau phosphorylation in Alzheimer's disease: pathogen or protector?

scientific article (publication date: April 2005)

Tau, Amyloid Beta and Deep Brain Stimulation: Aiming to Restore Cognitive Deficit in Alzheimer's Disease

scientific article published on 19 August 2016

Tau--an inhibitor of deacetylase HDAC6 function

scientific article

Tau-reactive neurofibrillary tangles in cerebellar cortex from patients with Alzheimer's disease

scientific article

Telomere length in Parkinson's disease: A meta-analysis

scientific article published on 6 January 2016

Telomeres and telomerase in Alzheimer's disease: epiphenomena or a new focus for therapeutic strategy?

scientific article

Temporal Primacy of Oxidative Stress in the Pathological Cascade of Alzheimer Disease

The "Down's" side of mitochondria

scientific article

The (un)balance between metabolic and oxidative abnormalities and cellular compensatory responses in Alzheimer disease

scientific article

The Alzheimer Precision Medicine Initiative

scientific article published on 01 January 2019

The Autistic Phenotype Exhibits a Remarkably Localized Modification of Brain Protein by Products of Free Radical-Induced Lipid Oxidation

scientific article published on 02 October 2009

The Changing landscape of Alzheimer’s disease: From Insoluble to Soluble and from Pathogen to Protector

The Interrelation of Neurological and Psychological Symptoms of COVID-19: Risks and Remedies

scientific article published on 13 August 2020

The Key Role of Oxidative Stress in Alzheimer's Disease

scholarly article published 2007

The Microbiota-Gut-Brain Axis-Heart Shunt Part II: Prosaic Foods and the Brain-Heart Connection in Alzheimer Disease

scientific article published on 31 March 2020

The Need to Separate Chronic Traumatic Encephalopathy Neuropathology from Clinical Features.

scientific article published on 30 October 2017

The Pathology of Alzheimer Disease Elicits an In Vivo Immunological Response

scholarly article by David J. Bonda et al published 1 January 2007 in American Journal of Immunology

The Potential Application of Antioxidant Agents in Alzheimer Disease Therapeutics

The Research Centers in Minority Institutions (RCMI) Translational Research Network: Building and Sustaining Capacity for Multi-Site Basic Biomedical, Clinical and Behavioral Research

scientific article published on 21 February 2019

The Role of Oxidative Damage to Nucleic Acids in the Pathogenesis of Neurological Disease

The Role of Oxidative Stress in the Pathological Sequelae of Alzheimer Disease

The Role of the Iron Stain in Assessing Intracranial Hemorrhage

scientific article published on 28 October 2016

The Transformative Possibilities of the Microbiota and Mycobiota for Health, Disease, Aging, and Technological Innovation

scientific article published on 28 March 2019

The amyloid cascade and Alzheimer's disease therapeutics: theory versus observation

scientific article published on 13 February 2019

The amyloid precursor protein in ischemic brain injury and chronic hypoperfusion

scientific article

The cell cycle and hormonal fluxes in Alzheimer disease: a novel therapeutic target

scientific article

The cell cycle in Alzheimer disease: a unique target for neuropharmacology

scientific article

The cell cycle regulator phosphorylated retinoblastoma protein is associated with tau pathology in several tauopathies

scientific article

The complexities of the pathology-pathogenesis relationship in Alzheimer disease

scientific article published on 18 January 2014

The concept of redox balance in Alzheimer's disease: Mark Anthony Smith 1965–2010

scholarly article by Xiongwei Zhu et al published March 2011 in Redox Report

The contribution of luteinizing hormone to Alzheimer disease pathogenesis

scientific article

The contribution of the amyloid hypothesis to the understanding of Alzheimer's disease: a critical overview.

scientific article

The earliest stage of cognitive impairment in transition from normal aging to Alzheimer disease is marked by prominent RNA oxidation in vulnerable neurons

scientific article published on March 2012

The effect of agonists and antagonists on the morphology of non-transformed human smooth muscle cell in vitro

scientific article published on January 1, 2001

The effect of mGluR2 activation on signal transduction pathways and neuronal cell survival

scientific article

The essential role of ERK in 4-oxo-2-nonenal-mediated cytotoxicity in SH-SY5Y human neuroblastoma cells

scientific article published on 13 January 2009

The estrogen myth: potential use of gonadotropin-releasing hormone agonists for the treatment of Alzheimer's disease

scientific article

The fallacy of amyloid and cognition in Alzheimer's disease

scientific article published in January 2006

The impairment of insulin signaling in Alzheimer's disease ⬇️

scientific article published on November 6, 2012

The mitochondrial common deletion in Parkinson's disease and related movement disorders

scientific article published in January 2002

The mitochondrial dynamics of Alzheimer's disease and Parkinson's disease offer important opportunities for therapeutic intervention

scientific article published on January 2011

The mosaic of brain glial hyperactivity during normal ageing and its attenuation by food restriction

scientific article published on March 1999

The neuronal expression of MYC causes a neurodegenerative phenotype in a novel transgenic mouse

scientific article published on 22 January 2009

The neuroprotective activities of melatonin against the Alzheimer beta-protein are not mediated by melatonin membrane receptors

scientific article

The origin of oxidative stress in neurodegenerative disease: Mark Anthony Smith 1965–2010

The p38 pathway is activated in Pick disease and progressive supranuclear palsy: a mechanistic link between mitogenic pathways, oxidative stress, and tau.

scientific article published in September 2002

The presence of tau distinguishes Lewy bodies of diffuse Lewy body disease from those of idiopathic Parkinson disease

scientific article published in May 1989

The primary pathogenetic role of vascular contains vasoactive substances, hypoperfusion, mitochondria failure and oxidative stress in aging and Alzheimer disease

The relationship of amyloid plaques to cerebral capillaries in Alzheimer's disease

scientific article

The role of abnormal mitochondrial dynamics in the pathogenesis of Alzheimer's disease

scientific article published on May 2009

The role of iron and copper in the aetiology of neurodegenerative disorders: therapeutic implications

scientific article

The role of iron as a mediator of oxidative stress in Alzheimer disease

scientific article published on 23 March 2012

The role of metabotropic glutamate receptors in Alzheimer's disease.

scientific article published on January 2004

The role of metals in neurodegenerative diseases.

scientific article published in June 2000

The role of mitogen-activated protein kinase pathways in Alzheimer's disease

scientific article

The role of nitric oxide in the pathogenesis of brain lesions during the development of Alzheimer's disease.

scientific article published in May 2004

The role of novel chitin-like polysaccharides in Alzheimer disease

scientific article published on December 2007

The role of oxidative stress in the pathophysiology of cerebrovascular lesions in Alzheimer's disease

scientific article

The state versus amyloid-beta: the trial of the most wanted criminal in Alzheimer disease

scientific article

The sterol regulatory element-binding protein 2 is dysregulated by tau alterations in Alzheimer disease

scientific article published on 28 January 2019

The structures of the E22Δ mutant-type amyloid-β alloforms and the impact of E22Δ mutation on the structures of the wild-type amyloid-β alloforms.

scientific article published on 18 December 2012

The up-regulation of BACE1 mediated by hypoxia and ischemic injury: role of oxidative stress and HIF1alpha

scientific article

The widespread alteration of neurites in Alzheimer's disease may be unrelated to amyloid deposition

scientific article published on December 1989

Therapeutic Opportunities in Alzheimer Disease: Current Concepts

Therapeutic opportunities in Alzheimer disease: one for all or all for one?

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Therapeutic options in Alzheimer's disease

scientific article published on June 2006

Therapeutic potential in Alzheimer disease

scientific article

Therapeutic potential of oxidant mechanisms in Alzheimer's disease

scientific article

Thermodynamics of Amyloid-β Fibril Elongation: Atomistic Details of the Transition State

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Thinking Outside the Box in Alzheimer Disease Treatment

Three histidine residues of amyloid-beta peptide control the redox activity of copper and iron

scientific article published on 11 October 2007

Three-dimensional tomographic imaging and characterization of iron compounds within Alzheimer's plaque core material

scientific article published in June 2008

Tipping the apoptotic balance in Alzheimer's disease: the abortosis concept

scientific article published on January 2003

Total antioxidant status in newly diagnosed Alzheimer's patients: Population based study

Towards an Integrative Understanding of tRNA Aminoacylation-Diet-Host-Gut Microbiome Interactions in Neurodegeneration.

scientific article published on 26 March 2018

Trace copper levels in the drinking water, but not zinc or aluminum influence CNS Alzheimer-like pathology

scientific article published on July 2006

Transcriptome-To-Metabolome™ Biosimulation Reveals Human Hippocampal Hypometabolism with Age and Alzheimer’s Disease

Transgenic Mouse Models of Alzheimer's Disease

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Transgenic Mouse Models of Alzheimer’s Disease: Behavioral Testing and Considerations ⬇️

scientific article published on January 5, 2011

Transplantation of Human Chorion-Derived Cholinergic Progenitor Cells: a Novel Treatment for Neurological Disorders

scientific article published on 16 March 2018

Treating the lesions, not the disease

scientific article published on May 2007

Treatment advances in Alzheimer's disease based on the oxidative stress model

scientific article

Trypsin interaction with the senile plaques of Alzheimer disease is mediated by beta-protein precursor

scientific article published in February 1996

Tryptamine induces axonopathy and mitochondriopathy mimicking neurodegenerative diseases via tryptophanyl-tRNA deficiency

scientific article

Two Hits and You’re Out? A Novel Mechanistic Hypothesis of Alzheimer Disease

Two hundred treasured issues!

scientific article

Ubiquitin is associated with abnormal cytoplasmic filaments characteristic of neurodegenerative diseases

scientific article

Ultrastructural analysis of a murine model of congenital hydrocephalus produced by overexpression of transforming growth factor-beta1 in the central nervous system.

scientific article

Ultrastructural localization of beta-amyloid, tau, and ubiquitin epitopes in extracellular neurofibrillary tangles ⬇️

scientific article published on March 15, 1991

Universal isolation of cross-linked peptides: application to neurofibrillary tangles

scientific article

Untangling the Vascular Web from Alzheimer Disease and Oxidative Stress ⬇️

scientific article published on January 1, 2012

Upregulation of presenilin 1 in brains of sporadic, late-onset Alzheimer's disease

scientific article published in January 2010

VASCULAR HYPOPERFUSION AND MITOCHONDRIA ABNORMALITY INDUCE OXIDATIVE STRESS THAT APPEARED TO BE A KEY FACTOR FOR THE DEVELOPMENT OF ALZHEIMER DISEASE

article

Variably protease-sensitive prionopathy: a new sporadic disease of the prion protein.

scientific article

Vascular Oxidative Stress: Impact and Therapeutic Approaches

scientific article published on 04 December 2018

Vascular abnormalities: the insidious pathogenesis of Alzheimer's disease

scientific article

Vascular oxidative stress in Alzheimer disease

scientific article

What are the facts and artifacts of the pathogenesis and etiology of Alzheimer disease?

scientific article

What is aging? What is its role in Alzheimer's disease? What can we do about it?

scientific article published in June 2005

Widespread distribution of reticulon-3 in various neurodegenerative diseases

scientific article

Widespread peroxynitrite-mediated damage in Alzheimer's disease

scientific article

Widespread serum amyloid P immunoreactivity in cortical amyloid deposits and the neurofibrillary pathology of Alzheimer's disease and other degenerative disorders

scientific article

Will Preventing Protein Aggregates Live Up to Its Promise as Prophylaxis Against Neurodegenerative Diseases?

article

Will antioxidants fulfill their expectations for the treatment of Alzheimer disease?

scientific article

Will preventing protein aggregates live up to its promise as prophylaxis against neurodegenerative diseases?

scientific article published on October 2003

William R. Markesbery, M.D.: A Tribute

article

X-ray contrast media induce aortic endothelial damage, which can be prevented with prior heparin treatment.

scientific article published on July 2003

beta PP and Tau interaction. A possible link between amyloid and neurofibrillary tangles in Alzheimer's disease

scientific article published on January 1996

beta-Amyloid of Alzheimer's disease induces reactive gliosis that inhibits axonal outgrowth

scientific article published in December 1993

c-Jun phosphorylation in Alzheimer disease

scientific article

α-Synuclein facilitates the toxicity of oxidized catechol metabolites: Implications for selective neurodegeneration in Parkinson's disease

article

β-amyloid 1-42 induces physiological transcriptional regulation of BACE1.

scientific article

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