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List of works by Hironobu Ikehata

A model for triplet mutation formation based on error-prone translesional DNA synthesis opposite UV photolesions

scientific article published on 31 January 2007

Absence of Ku70 gene obliterates X-ray-induced lacZ mutagenesis of small deletions in mouse tissues.

scientific article published in August 2008

Absence of mutagenic effects of 2.45 GHz radiofrequency exposure in spleen, liver, brain, and testis of lacZ-transgenic mouse exposed in utero

scientific article published on 01 February 2004

Action spectrum analysis of UVR genotoxicity for skin: the border wavelengths between UVA and UVB can bring serious mutation loads to skin.

scientific article published on 14 February 2013

Age-associated increase of spontaneous mutant frequency and molecular nature of mutation in newborn and old lacZ-transgenic mouse.

scientific article published in February 2000

Analysis of mutation spectra in UVB-exposed mouse skin epidermis and dermis: frequent occurrence of C-->T transition at methylated CpG-associated dipyrimidine sites

scientific article published on 01 January 2003

Antigenotoxic effects of p53 on spontaneous and ultraviolet light B--induced deletions in the epidermis of gpt delta transgenic mice.

scientific article

Chromatin fine structure of the c-MYC insulator element/DNase I-hypersensitive site I is not preserved during mitosis.

scholarly article

Effects of calorie restriction on the age-dependent accumulation of mutations in the small intestine of lacZ-transgenic mice

scientific article published on 12 February 2011

Frequent recovery of triplet mutations in UVB-exposed skin epidermis of Xpc-knockout mice

scientific article published on 17 October 2006

Fully functional global genome repair of (6-4) photoproducts and compromised transcription-coupled repair of cyclobutane pyrimidine dimers in condensed mitotic chromatin

scientific article published on 8 January 2012

In Vivo Spectrum of UVC-induced Mutation in Mouse Skin Epidermis May Reflect the Cytosine Deamination Propensity of Cyclobutane Pyrimidine Dimers

scientific article published on 13 October 2015

Influences of p53 deficiency on the apoptotic response, DNA damage removal and mutagenesis in UVB-exposed mouse skin

scientific article

Mechanistic considerations on the wavelength-dependent variations of UVR genotoxicity and mutagenesis in skin: the discrimination of UVA-signature from UV-signature mutation

scientific article published on 01 December 2018

Molecular nature of mutations induced by irradiation with repeated low doses of X-rays in spleen, liver, brain and testis of lacZ-transgenic mice.

scientific article

Mutation induction with UVB in mouse skin epidermis is suppressed in acute high-dose exposure

scientific article published on 01 October 2002

Mutation spectrum in UVB-exposed skin epidermis of Xpa-knockout mice: frequent recovery of triplet mutations

scientific article

Mutation spectrum in UVB-exposed skin epidermis of a mildly-affected Xpg-deficient mouse

scientific article published on 01 March 2006

Mutation spectrum in sunlight-exposed mouse skin epidermis: small but appreciable contribution of oxidative stress-mediated mutagenesis

scientific article published on 01 November 2004

Mutation theory of aging, assessed in transgenic mice and knockout mice.

scientific article

Quantitative analysis of UV photolesions suggests that cyclobutane pyrimidine dimers produced in mouse skin by UVB are more mutagenic than those produced by UVC.

scientific article published on 21 February 2018

Remarkable induction of UV-signature mutations at the 3'-cytosine of dipyrimidine sites except at 5'-TCG-3' in the UVB-exposed skin epidermis of xeroderma pigmentosum variant model mice.

scientific article published on 14 August 2014

Role of the Msh2 gene in genome maintenance and development in mouse fetuses.

scientific article published on 21 March 2012

Roles of the KEAP1-NRF2 system in mammalian skin exposed to UV radiation

scientific article published on 28 September 2018

Seasonal Differences in the UVA/UVB Ratio of Natural Sunlight Influence the Efficiency of the Photoisomerization of (6-4) Photoproducts into their Dewar Valence Isomers

scientific article published on 03 December 2020

Shuttle vector system for the analysis of mutational events in mammalian chromosomal DNA.

scientific article published on February 1989

Significance of CpG methylation for solar UV-induced mutagenesis and carcinogenesis in skin.

scientific article

Skin can control solar UVR-induced mutations through the epidermis-specific response of mutation induction suppression

scientific article published on 01 November 2013

Solar-UV-signature mutation prefers TCG to CCG: extrapolative consideration from UVA1-induced mutation spectra in mouse skin ⬇️

scientific article published on August 1, 2013

Spectrum of spontaneous mutations in a cDNA of the human hprt gene integrated in chromosomal DNA

scientific article published on 01 November 1989

Spontaneous mutant frequency of lacZ gene in spleen of transgenic mouse increases with age

scientific article published on 01 October 1995

Spontaneous mutations in digestive tract of old mice show tissue-specific patterns of genomic instability

scientific article published on 01 October 2004

The Mechanisms of UV Mutagenesis ⬇️

scientific article published on January 1, 2011

Thermolysin improves mutation analysis in skin epidermis from ultraviolet light-irradiated Muta Mouse

scientific article published on 01 January 2001

UVA induces C-->T transitions at methyl-CpG-associated dipyrimidine sites in mouse skin epidermis more frequently than UVB.

scientific article published in November 2003

UVA1 genotoxicity is mediated not by oxidative damage but by cyclobutane pyrimidine dimers in normal mouse skin

scientific article

Wavelength- and Tissue-dependent Variations in the Mutagenicity of Cyclobutane Pyrimidine Dimers in Mouse Skin

scientific article published on 15 October 2019

X-ray- and ultraviolet-radiation-induced mutations in Muta mouse

scientific article published on 01 August 1997

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