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List of works by Susanne Schiffmann

Alpha-methylacyl-CoA racemase deletion has mutually counteracting effects on T-cell responses, associated with unchanged course of EAE.

scientific article published on 9 December 2015

Biosynthesis of riboflavin in archaea studies on the mechanism of 3,4-dihydroxy-2-butanone-4-phosphate synthase of Methanococcus jannaschii

scientific article published on 27 August 2002

Cellular membranes function as a storage compartment for celecoxib

scientific article

Ceramide Synthase 6 Plays a Critical Role in the Development of Experimental Autoimmune Encephalomyelitis

article

Ceramide metabolism in mouse tissue

scientific article published on 19 June 2013

Ceramide synthases CerS4 and CerS5 are upregulated by 17β-estradiol and GPER1 via AP-1 in human breast cancer cells

scientific article

Ceramide synthases and ceramide levels are increased in breast cancer tissue

scientific article

Chain length-specific properties of ceramides

scientific article

Crystal structure of rat GTP cyclohydrolase I feedback regulatory protein, GFRP

scientific article

Cyclooxygenase-2 (COX-2)-independent anticarcinogenic effects of selective COX-2 inhibitors

scientific article

DNA: a programmable force sensor

scientific article

Dietary phytol reduces clinical symptoms in experimental autoimmune encephalomyelitis (EAE) at least partially by modulating NOX2 expression

article

Dimethylcelecoxib inhibits prostaglandin E2 production

scientific article published on 24 April 2008

Double chip protein arrays using recombinant single-chain Fv antibody fragments

scientific article published in May 2004

Double-chip protein arrays: force-based multiplex sandwich immunoassays with increased specificity

scientific article

Dysregulation of lysophosphatidic acids in multiple sclerosis and autoimmune encephalomyelitis.

scientific article

Evidence of COX-2 independent induction of apoptosis and cell cycle block in human colon carcinoma cells after S- or R-ibuprofen treatment

scientific article published on 3 May 2006

Exacerbation of experimental autoimmune encephalomyelitis in ceramide synthase 6 knockout mice is associated with enhanced activation/migration of neutrophils

scientific article published on 2 April 2015

Immunogenicity assay development and validation for biological therapy as exemplified by ustekinumab

scientific article published on 03 February 2019

In Vitro Safety, Off-Target and Bioavailability Profile of the Antiviral Compound Silvestrol

scientific article published in 2022

Induction of Experimental Autoimmune Encephalomyelitis in Mice and Evaluation of the Disease-dependent Distribution of Immune Cells in Various Tissues.

scientific article

Inhibitors of specific ceramide synthases

scientific article published on 17 September 2011

Lack of ceramide synthase 2 suppresses the development of experimental autoimmune encephalomyelitis by impairing the migratory capacity of neutrophils

scientific article published on 16 February 2015

Long chain ceramides and very long chain ceramides have opposite effects on human breast and colon cancer cell growth

scientific article published on 2 January 2012

Machine-Learned Data Structures of Lipid Marker Serum Concentrations in Multiple Sclerosis Patients Differ from Those in Healthy Subjects

scientific article

Metal sites in 3,4-dihydroxy-2-butanone 4-phosphate synthase from Methanococcus jannaschii in complex with the substrate ribulose 5-phosphate

scientific article

Microarray analysis of altered sphingolipid metabolism reveals prognostic significance of sphingosine kinase 1 in breast cancer.

scientific article published on 4 December 2007

Multiple rodent models and behavioral measures reveal unexpected responses to FTY720 and DMF in experimental autoimmune encephalomyelitis.

scientific article published on 12 December 2015

Nano-LC-MS/MS for the quantitation of ceramides in mice cerebrospinal fluid using minimal sample volume

scientific article published on 9 August 2013

Nanocarriers for photodynamic therapy-rational formulation design and medium-scale manufacture

scientific article published on 26 June 2015

Natural antiviral compound silvestrol modulates human monocyte-derived macrophages and dendritic cells

scientific article published on 06 May 2020

PGE2/EP4 signaling in peripheral immune cells promotes development of experimental autoimmune encephalomyelitis

scientific article published on 16 December 2013

Promoter Activation in Δhfq Mutants as an Efficient Tool for Specialized Metabolite Production Enabling Direct Bioactivity Testing ⬇️

scientific article published on 12 December 2019

Regulation of ceramide synthase 6 in a spontaneous experimental autoimmune encephalomyelitis model is sex dependent

scientific article published on 27 August 2014

Sphingosine kinase 2 deficient tumor xenografts show impaired growth and fail to polarize macrophages towards an anti-inflammatory phenotype

scientific article

Structure of 3,4-dihydroxy-2-butanone 4-phosphate synthase from Methanococcus jannaschii in complex with divalent metal ions and the substrate ribulose 5-phosphate: implications for the catalytic mechanism

scientific article

The NMR structure of the 47-kDa dimeric enzyme 3,4-dihydroxy-2-butanone-4-phosphate synthase and ligand binding studies reveal the location of the active site

scientific article

The Pharmacological Potential of Novel Melittin Variants from the Honeybee and Solitary Bees against Inflammation and Cancer

scientific article published in 2022

The anti-proliferative potency of celecoxib is not a class effect of coxibs

scientific article

The enigma of ceramide synthase regulation in mammalian cells

scientific article published on 13 May 2016

The equilibrium between long and very long chain ceramides is important for the fate of the cell and can be influenced by co-expression of CerS.

scientific article published on 26 March 2013

The selective COX-2 inhibitor celecoxib modulates sphingolipid synthesis

scientific article

p53 is important for the anti-proliferative effect of ibuprofen in colon carcinoma cells

scientific article published on 26 November 2007

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