List of works - Cornelia C. Bergmann

Activated GL7+ B cells are maintained within the inflamed CNS in the absence of follicle formation during viral encephalomyelitis.

scientific article published on 19 September 2016

Altered neuroantigen-specific cytokine secretion in a Th2 environment reduces experimental autoimmune encephalomyelitis.

scientific article published on 30 June 2006

An endogenously synthesized decamer peptide efficiently primes cytotoxic T cells specific for the HIV-1 envelope glycoprotein.

scientific article

An optimized method for enumerating CNS derived memory B cells during viral-induced inflammation.

scientific article published on 8 May 2017

Astrocyte expression of a dominant-negative interferon-gamma receptor.

scientific article published in October 2005

Astrocyte response to IFN-γ limits IL-6-mediated microglia activation and progressive autoimmune encephalomyelitis

scientific article published on 22 April 2015

Astrocyte-derived CXCL10 drives accumulation of antibody-secreting cells in the central nervous system during viral encephalomyelitis

scientific article published on 9 January 2013

Astrocyte-restricted ablation of interleukin-17-induced Act1-mediated signaling ameliorates autoimmune encephalomyelitis

scientific article

CC chemokine ligand 3 (CCL3) regulates CD8(+)-T-cell effector function and migration following viral infection.

scientific article

CD4 T cells contribute to virus control and pathology following central nervous system infection with neurotropic mouse hepatitis virus.

scientific article

CD4 T cells promote CD8 T cell immunity at the priming and effector site during viral encephalitis

scientific article published on 28 December 2011

CNS viral infection diverts homing of antibody-secreting cells from lymphoid organs to the CNS.

scientific article published in March 2006

CXCL13 promotes isotype-switched B cell accumulation to the central nervous system during viral encephalomyelitis

scientific article published on 18 January 2016

CXCR3-dependent plasma blast migration to the central nervous system during viral encephalomyelitis

scientific article

Contributions of CD8+ T cells and viral spread to demyelinating disease.

scientific article published on April 2000

Control of central nervous system viral persistence by neutralizing antibody

scientific article

Coronavirus immunity: from T cells to B cells.

scientific article published on January 2006

Coronavirus infection of the central nervous system: host-virus stand-off

scientific article

Coronavirus translational regulation: leader affects mRNA efficiency.

scientific article published on August 1994

Differential Regulation of Self-reactive CD4+ T Cells in Cervical Lymph Nodes and Central Nervous System during Viral Encephalomyelitis

scientific article published on 21 September 2016

Distinct CD4 T-cell effects on primary versus recall CD8 T-cell responses during viral encephalomyelitis

scientific article published on 4 September 2014

Early endonuclease-mediated evasion of RNA sensing ensures efficient coronavirus replication

scientific article

Efficient induction of primary and secondary T cell-dependent immune responses in vivo in the absence of functional IL-2 and IL-15 receptors

scientific article published on 01 January 2003

Enhanced CD8 T-cell anti-viral function and clinical disease in B7-H1-deficient mice requires CD4 T cells during encephalomyelitis.

scientific article published on 14 December 2012

Enhanced antiviral T cell function in the absence of B7-H1 is insufficient to prevent persistence but exacerbates axonal bystander damage during viral encephalomyelitis.

scientific article

Expression of a dominant negative IFN-gammareceptor on mouse oligodendrocytes

scientific article

Expression of matrix metalloproteinases and their tissue inhibitor during viral encephalitis.

scientific article

Expression of the mouse hepatitis virus receptor by central nervous system microglia

scientific article

Factors supporting intrathecal humoral responses following viral encephalomyelitis.

scientific article

Gamma interferon signaling in oligodendrocytes is critical for protection from neurotropic coronavirus infection

scientific article

IFN-γ protects from lethal IL-17 mediated viral encephalomyelitis independent of neutrophils

scientific article

IFN-γ signaling to astrocytes protects from autoimmune mediated neurological disability

scientific article

IL-15 independent maintenance of virus-specific CD8(+) T cells in the CNS during chronic infection.

scientific article published on 23 December 2008

IL-21 optimizes T cell and humoral responses in the central nervous system during viral encephalitis

scientific article published on 06 August 2013

IL-27 limits central nervous system viral clearance by promoting IL-10 and enhances demyelination.

scientific article

Ifit2 deficiency restricts microglial activation and leukocyte migration following murine coronavirus (m-CoV) CNS infection

scientific article published on 30 November 2020

Ifit2 deficiency results in uncontrolled neurotropic coronavirus replication and enhanced encephalitis via impaired alpha/beta interferon induction in macrophages

scientific article

Impaired T cell immunity in B cell-deficient mice following viral central nervous system infection

scientific article published on 01 August 2001

Induction of class I antigen processing components in oligodendroglia and microglia during viral encephalomyelitis.

scientific article

Inhibition of interferon-gamma signaling in oligodendroglia delays coronavirus clearance without altering demyelination

scientific article

Interaction of rotavirus cores with the nonstructural glycoprotein NS28

scientific article published on 01 July 1989

Interferon-induced Ifit2/ISG54 protects mice from lethal VSV neuropathogenesis

scientific article

Interleukin-10 is a critical regulator of white matter lesion containment following viral induced demyelination

scientific article published on 30 June 2015

Interleukin-12 (IL-12), but not IL-23, deficiency ameliorates viral encephalitis without affecting viral control

scientific article published on April 2009

Intrathecal humoral immunity to encephalitic RNA viruses.

scientific article published on 15 February 2013

Kinetics of virus-specific CD8+ -T-cell expansion and trafficking following central nervous system infection

scientific article

Lipopolysaccharide-induced microglial activation and neuroprotection against experimental brain injury is independent of hematogenous TLR4

scientific article published on August 2012

Liver X receptor activation decreases the severity of experimental autoimmune encephalomyelitis.

scientific article published in November 2006

MHV infection of the CNS: mechanisms of immune-mediated control.

scientific article

MMP-independent role of TIMP-1 at the blood brain barrier during viral encephalomyelitis.

scientific article

MMP9 deficiency does not decrease blood-brain barrier disruption, but increases astrocyte MMP3 expression during viral encephalomyelitis.

scientific article

Maintenance of CD8(+) T-cell memory following infection with recombinant sindbis and vaccinia viruses.

scientific article published on April 2000

Mechanisms of central nervous system viral persistence: the critical role of antibody and B cells.

scientific article

Memory CD4+ T-cell-mediated protection from lethal coronavirus encephalomyelitis.

scientific article published on 08 October 2008

Microglia exhibit clonal variability in eliciting cytotoxic T lymphocyte responses independent of class I expression.

scientific article

Monocytes regulate T cell migration through the glia limitans during acute viral encephalitis

scientific article

Mouse hepatitis virus nucleocapsid protein-specific cytotoxic T lymphocytes are Ld restricted and specific for the carboxy terminus ⬇️

scientific article published on July 1, 1992

Mouse hepatitis virus pathogenesis in the central nervous system is independent of IL-15 and natural killer cells.

scientific article published on 28 February 2006

Myd88 Initiates Early Innate Immune Responses and Promotes CD4 T Cells during Coronavirus Encephalomyelitis.

scientific article

Natural killer T cell ligand alpha-galactosylceramide enhances protective immunity induced by malaria vaccines

scientific article

Neuroimmunology of central nervous system viral infections: the cells, molecules and mechanisms involved.

scientific article published on 16 June 2008

Oligodendroglia are limited in type I interferon induction and responsiveness in vivo

scientific article

PKR mediated regulation of inflammation and IL-10 during viral encephalomyelitis

scientific article

Perforin and gamma interferon-mediated control of coronavirus central nervous system infection by CD8 T cells in the absence of CD4 T cells

scientific article published on February 2004

Progression from IgD+ IgM+ to isotype-switched B cells is site specific during coronavirus-induced encephalomyelitis.

scientific article

Protective Humoral Immunity in the CNS Requires Peripheral CD19-Dependent Germinal Center Formation Following Coronavirus Encephalomyelitis.

scientific article published on 20 September 2017

RNase L mediated protection from virus induced demyelination

scientific article

Role of CD25(+) CD4(+) T cells in acute and persistent coronavirus infection of the central nervous system

scientific article published on 24 September 2013

Role of viral persistence in retaining CD8(+) T cells within the central nervous system

scientific article

Rotavirus VP6 modified for expression on the plasma membrane forms arrays and exhibits enhanced immunogenicity

scientific article published on August 1, 1992

Self-reactive CD4(+) T cells activated during viral-induced demyelination do not prevent clinical recovery

scientific article

Shifting hierarchies of interleukin-10-producing T cell populations in the central nervous system during acute and persistent viral encephalomyelitis.

scientific article

Sustained TNF production by central nervous system infiltrating macrophages promotes progressive autoimmune encephalomyelitis

scientific article published on 22 February 2016

Target-dependent B7-H1 regulation contributes to clearance of central nervous system infection and dampens morbidity.

scientific article

Type I interferons are essential in controlling neurotropic coronavirus infection irrespective of functional CD8 T cells.

scientific article

Variability of Persisting MHV RNA Sequences Constituting Immune and Replication-Relevant Domains ⬇️

scientific article published on May 10, 1998

Viral-induced suppression of self-reactive T cells: Lessons from neurotropic coronavirus-induced demyelination

scientific article published on 11 January 2017

Virus-specific and bystander CD8 T cells recruited during virus-induced encephalomyelitis

scientific article

List of works by Cornelia C. Bergmann

Activated GL7+ B cells are maintained within the inflamed CNS in the absence of follicle formation during viral encephalomyelitis.

Altered neuroantigen-specific cytokine secretion in a Th2 environment reduces experimental autoimmune encephalomyelitis.

An endogenously synthesized decamer peptide efficiently primes cytotoxic T cells specific for the HIV-1 envelope glycoprotein.

An optimized method for enumerating CNS derived memory B cells during viral-induced inflammation.

Astrocyte expression of a dominant-negative interferon-gamma receptor.

Astrocyte response to IFN-γ limits IL-6-mediated microglia activation and progressive autoimmune encephalomyelitis

Astrocyte-derived CXCL10 drives accumulation of antibody-secreting cells in the central nervous system during viral encephalomyelitis

Astrocyte-restricted ablation of interleukin-17-induced Act1-mediated signaling ameliorates autoimmune encephalomyelitis

CC chemokine ligand 3 (CCL3) regulates CD8(+)-T-cell effector function and migration following viral infection.

CD4 T cells contribute to virus control and pathology following central nervous system infection with neurotropic mouse hepatitis virus.

CD4 T cells promote CD8 T cell immunity at the priming and effector site during viral encephalitis

CNS viral infection diverts homing of antibody-secreting cells from lymphoid organs to the CNS.

CXCL13 promotes isotype-switched B cell accumulation to the central nervous system during viral encephalomyelitis

CXCR3-dependent plasma blast migration to the central nervous system during viral encephalomyelitis

Contributions of CD8+ T cells and viral spread to demyelinating disease.

Control of central nervous system viral persistence by neutralizing antibody

Coronavirus immunity: from T cells to B cells.

Coronavirus infection of the central nervous system: host-virus stand-off

Coronavirus translational regulation: leader affects mRNA efficiency.

Differential Regulation of Self-reactive CD4+ T Cells in Cervical Lymph Nodes and Central Nervous System during Viral Encephalomyelitis

Distinct CD4 T-cell effects on primary versus recall CD8 T-cell responses during viral encephalomyelitis

Early endonuclease-mediated evasion of RNA sensing ensures efficient coronavirus replication

Efficient induction of primary and secondary T cell-dependent immune responses in vivo in the absence of functional IL-2 and IL-15 receptors

Enhanced CD8 T-cell anti-viral function and clinical disease in B7-H1-deficient mice requires CD4 T cells during encephalomyelitis.

Enhanced antiviral T cell function in the absence of B7-H1 is insufficient to prevent persistence but exacerbates axonal bystander damage during viral encephalomyelitis.

Expression of a dominant negative IFN-gammareceptor on mouse oligodendrocytes

Expression of matrix metalloproteinases and their tissue inhibitor during viral encephalitis.

Expression of the mouse hepatitis virus receptor by central nervous system microglia

Factors supporting intrathecal humoral responses following viral encephalomyelitis.

Gamma interferon signaling in oligodendrocytes is critical for protection from neurotropic coronavirus infection

IFN-γ protects from lethal IL-17 mediated viral encephalomyelitis independent of neutrophils

IFN-γ signaling to astrocytes protects from autoimmune mediated neurological disability

IL-15 independent maintenance of virus-specific CD8(+) T cells in the CNS during chronic infection.

IL-21 optimizes T cell and humoral responses in the central nervous system during viral encephalitis

IL-27 limits central nervous system viral clearance by promoting IL-10 and enhances demyelination.

Ifit2 deficiency restricts microglial activation and leukocyte migration following murine coronavirus (m-CoV) CNS infection

Ifit2 deficiency results in uncontrolled neurotropic coronavirus replication and enhanced encephalitis via impaired alpha/beta interferon induction in macrophages

Impaired T cell immunity in B cell-deficient mice following viral central nervous system infection

Induction of class I antigen processing components in oligodendroglia and microglia during viral encephalomyelitis.

Inhibition of interferon-gamma signaling in oligodendroglia delays coronavirus clearance without altering demyelination

Interaction of rotavirus cores with the nonstructural glycoprotein NS28

Interferon-induced Ifit2/ISG54 protects mice from lethal VSV neuropathogenesis

Interleukin-10 is a critical regulator of white matter lesion containment following viral induced demyelination

Interleukin-12 (IL-12), but not IL-23, deficiency ameliorates viral encephalitis without affecting viral control

Intrathecal humoral immunity to encephalitic RNA viruses.

Kinetics of virus-specific CD8+ -T-cell expansion and trafficking following central nervous system infection

Lipopolysaccharide-induced microglial activation and neuroprotection against experimental brain injury is independent of hematogenous TLR4

Liver X receptor activation decreases the severity of experimental autoimmune encephalomyelitis.

MHV infection of the CNS: mechanisms of immune-mediated control.

MMP-independent role of TIMP-1 at the blood brain barrier during viral encephalomyelitis.

MMP9 deficiency does not decrease blood-brain barrier disruption, but increases astrocyte MMP3 expression during viral encephalomyelitis.

Maintenance of CD8(+) T-cell memory following infection with recombinant sindbis and vaccinia viruses.

Mechanisms of central nervous system viral persistence: the critical role of antibody and B cells.

Memory CD4+ T-cell-mediated protection from lethal coronavirus encephalomyelitis.

Microglia exhibit clonal variability in eliciting cytotoxic T lymphocyte responses independent of class I expression.

Monocytes regulate T cell migration through the glia limitans during acute viral encephalitis

Mouse hepatitis virus nucleocapsid protein-specific cytotoxic T lymphocytes are Ld restricted and specific for the carboxy terminus ⬇️

Mouse hepatitis virus pathogenesis in the central nervous system is independent of IL-15 and natural killer cells.

Myd88 Initiates Early Innate Immune Responses and Promotes CD4 T Cells during Coronavirus Encephalomyelitis.

Natural killer T cell ligand alpha-galactosylceramide enhances protective immunity induced by malaria vaccines

Neuroimmunology of central nervous system viral infections: the cells, molecules and mechanisms involved.

Oligodendroglia are limited in type I interferon induction and responsiveness in vivo

PKR mediated regulation of inflammation and IL-10 during viral encephalomyelitis

Perforin and gamma interferon-mediated control of coronavirus central nervous system infection by CD8 T cells in the absence of CD4 T cells

Progression from IgD+ IgM+ to isotype-switched B cells is site specific during coronavirus-induced encephalomyelitis.

Protective Humoral Immunity in the CNS Requires Peripheral CD19-Dependent Germinal Center Formation Following Coronavirus Encephalomyelitis.

RNase L mediated protection from virus induced demyelination

Role of CD25(+) CD4(+) T cells in acute and persistent coronavirus infection of the central nervous system

Role of viral persistence in retaining CD8(+) T cells within the central nervous system

Rotavirus VP6 modified for expression on the plasma membrane forms arrays and exhibits enhanced immunogenicity

Self-reactive CD4(+) T cells activated during viral-induced demyelination do not prevent clinical recovery

Shifting hierarchies of interleukin-10-producing T cell populations in the central nervous system during acute and persistent viral encephalomyelitis.

Sustained TNF production by central nervous system infiltrating macrophages promotes progressive autoimmune encephalomyelitis

Target-dependent B7-H1 regulation contributes to clearance of central nervous system infection and dampens morbidity.

Type I interferons are essential in controlling neurotropic coronavirus infection irrespective of functional CD8 T cells.

Variability of Persisting MHV RNA Sequences Constituting Immune and Replication-Relevant Domains ⬇️

Viral-induced suppression of self-reactive T cells: Lessons from neurotropic coronavirus-induced demyelination

Virus-specific and bystander CD8 T cells recruited during virus-induced encephalomyelitis