List of works - Pierre Colas

A RasGAP SH3 peptide aptamer inhibits RasGAP-Aurora interaction and induces caspase-independent tumor cell death

scientific article

A comparative analysis of perturbations caused by a gene knock-out, a dominant negative allele, and a set of peptide aptamers.

scientific article published on 4 September 2007

A homozygous deleterious CDK10 mutation in a patient with agenesis of corpus callosum, retinopathy, and deafness

scientific article published on 12 November 2017

A small molecule screen in yeast identifies inhibitors targeting protein-protein interactions within the vaccinia virus replication complex

scientific article

A universal transgene silencing method based on RNA interference

scientific article published on 12 July 2004

An antiproliferative genetic screening identifies a peptide aptamer that targets calcineurin and up-regulates its activity

scientific article

An artificial cell-cycle inhibitor isolated from a combinatorial library

scientific article

Calcineurin A versus NS5A-TP2/HD domain containing 2: a case study of site-directed low-frequency random mutagenesis for dissecting target specificity of peptide aptamers

scientific article

Characterization of peptide aptamers targeting Bfl-1 anti-apoptotic protein.

scientific article published on 20 May 2011

Combinatorial protein reagents to manipulate protein function.

scientific article

Cyclin A-Cys41 does not undergo cell cycle-dependent degradation in Xenopus extracts

scientific article published on July 13, 1992

Cyclin-dependent kinases and rare developmental disorders

scientific article published on 06 August 2020

First BRET-based screening assay performed in budding yeast leads to the discovery of CDK5/p25 interaction inhibitors.

scientific article

From Peptide Aptamers to Inhibitors of FUR, Bacterial Transcriptional Regulator of Iron Homeostasis and Virulence

scientific article published on 13 July 2016

High-throughput screening assays to discover small-molecule inhibitors of protein interactions.

scientific article published on September 2008

Inhibition of heat shock protein 27 (HspB1) tumorigenic functions by peptide aptamers.

scientific article published on 21 March 2011

Inhibition of vaccinia virus replication by peptide aptamers

scientific article

Meiotic maturation in mollusc oocytes.

scientific article published in October 1998

Microinjection of suc1 transcripts delays the cell cycle clock in Patella vulgata embryos.

scientific article published in December 1993

Modulation of Nr-13 antideath activity by peptide aptamers.

scientific article

Natural product extracts of the Canadian prairie plant, Thermopsis rhombifolia, have anti-cancer activity in phenotypic cell-based assays

scientific article

Peptide aptamers as guides for small-molecule drug discovery.

scientific article

Peptide aptamers for small molecule drug discovery

scientific article

Peptides and aptamers targeting HSP70: a novel approach for anticancer chemotherapy

scientific article published on 11 January 2011

Pyrazolo[1,5-a]-1,3,5-triazine as a purine bioisostere: access to potent cyclin-dependent kinase inhibitor (R)-roscovitine analogue.

scientific article published on February 2009

STAR syndrome-associated CDK10/Cyclin M regulates actin network architecture and ciliogenesis.

scientific article published on March 2016

Screening for Protein-Protein Interaction Inhibitors Using a Bioluminescence Resonance Energy Transfer (BRET)–Based Assay in Yeast

scientific article published on 31 January 2017

Selection and characterization of large collections of peptide aptamers through optimized yeast two-hybrid procedures

scientific article

Tamoxifen inhibits CDK5 kinase activity by interacting with p35/p25 and modulates the pattern of tau phosphorylation.

scientific article

Tampering with cell division by using small-molecule inhibitors of CDK-CKS protein interactions

scientific article published on 23 January 2015

Targeting cancer with peptide aptamers.

scientific article published on July 2011

The awakening of the CDK10/Cyclin M protein kinase

scientific article published on 2 February 2017

The eleven-year switch of peptide aptamers.

scientific article published on January 2008

The impact of two-hybrid and related methods on biotechnology

scientific article published on 01 August 1998

The oocyte metaphase arrest ⬇️

scientific article published on January 1, 1995

The role of cyclins in the maturation of Patella vulgata oocytes ⬇️

scientific article published on November 1, 1991

Yeast two-hybrid methods and their applications in drug discovery.

scientific article

p53-dependent inhibition of mammalian cell survival by a genetically selected peptide aptamer that targets the regulatory subunit of protein kinase CK2.

scientific article published on 5 June 2006

List of works by Pierre Colas

A RasGAP SH3 peptide aptamer inhibits RasGAP-Aurora interaction and induces caspase-independent tumor cell death

A comparative analysis of perturbations caused by a gene knock-out, a dominant negative allele, and a set of peptide aptamers.

A homozygous deleterious CDK10 mutation in a patient with agenesis of corpus callosum, retinopathy, and deafness

A small molecule screen in yeast identifies inhibitors targeting protein-protein interactions within the vaccinia virus replication complex

A universal transgene silencing method based on RNA interference

An antiproliferative genetic screening identifies a peptide aptamer that targets calcineurin and up-regulates its activity

An artificial cell-cycle inhibitor isolated from a combinatorial library

Calcineurin A versus NS5A-TP2/HD domain containing 2: a case study of site-directed low-frequency random mutagenesis for dissecting target specificity of peptide aptamers

Characterization of peptide aptamers targeting Bfl-1 anti-apoptotic protein.

Combinatorial protein reagents to manipulate protein function.

Cyclin A-Cys41 does not undergo cell cycle-dependent degradation in Xenopus extracts

Cyclin-dependent kinases and rare developmental disorders

First BRET-based screening assay performed in budding yeast leads to the discovery of CDK5/p25 interaction inhibitors.

From Peptide Aptamers to Inhibitors of FUR, Bacterial Transcriptional Regulator of Iron Homeostasis and Virulence

High-throughput screening assays to discover small-molecule inhibitors of protein interactions.

Inhibition of heat shock protein 27 (HspB1) tumorigenic functions by peptide aptamers.

Inhibition of vaccinia virus replication by peptide aptamers

Meiotic maturation in mollusc oocytes.

Microinjection of suc1 transcripts delays the cell cycle clock in Patella vulgata embryos.

Modulation of Nr-13 antideath activity by peptide aptamers.

Natural product extracts of the Canadian prairie plant, Thermopsis rhombifolia, have anti-cancer activity in phenotypic cell-based assays

Peptide aptamers as guides for small-molecule drug discovery.

Peptide aptamers for small molecule drug discovery

Peptides and aptamers targeting HSP70: a novel approach for anticancer chemotherapy

Pyrazolo[1,5-a]-1,3,5-triazine as a purine bioisostere: access to potent cyclin-dependent kinase inhibitor (R)-roscovitine analogue.

STAR syndrome-associated CDK10/Cyclin M regulates actin network architecture and ciliogenesis.

Screening for Protein-Protein Interaction Inhibitors Using a Bioluminescence Resonance Energy Transfer (BRET)–Based Assay in Yeast

Selection and characterization of large collections of peptide aptamers through optimized yeast two-hybrid procedures

Tamoxifen inhibits CDK5 kinase activity by interacting with p35/p25 and modulates the pattern of tau phosphorylation.

Tampering with cell division by using small-molecule inhibitors of CDK-CKS protein interactions

Targeting cancer with peptide aptamers.

The awakening of the CDK10/Cyclin M protein kinase

The eleven-year switch of peptide aptamers.

The impact of two-hybrid and related methods on biotechnology

The oocyte metaphase arrest ⬇️

The role of cyclins in the maturation of Patella vulgata oocytes ⬇️

Yeast two-hybrid methods and their applications in drug discovery.

p53-dependent inhibition of mammalian cell survival by a genetically selected peptide aptamer that targets the regulatory subunit of protein kinase CK2.