List of works - Lee Niswander

A hypomorphic allele reveals an important role of inturned in mouse skeletal development

scientific journal article

A mouse model for Meckel syndrome reveals Mks1 is required for ciliogenesis and Hedgehog signaling

scientific journal article

A positive feedback loop coordinates growth and patterning in the vertebrate limb.

scientific article

A unique missense allele of BAF155, a core BAF chromatin remodeling complex protein, causes neural tube closure defects in mice

scientific article

ALC (adjacent to LMX1 in chick) is a novel dorsal limb mesenchyme marker

scientific article published on 01 December 2003

An explant muscle model to examine the refinement of the synaptic landscape

scientific article

BMP Expression in Duck Interdigital Webbing: A Reanalysis

scientific article published in Science

BMPs are required at two steps of limb chondrogenesis: formation of prechondrogenic condensations and their differentiation into chondrocytes

scientific article published on 01 March 2000

C2cd3 is required for cilia formation and Hedgehog signaling in mouse.

scientific article

Canonical Wnt signaling negatively regulates branching morphogenesis of the lung and lacrimal gland.

scientific article published in October 2005

Cell polarity pathways converge and extend to regulate neural tube closure.

scientific article

Chromosome jumping from flanking markers defines the minimal region for alf/hsdr-1 within the albino-deletion complex

scientific article published on October 1, 1992

Coordinate regulation of neural tube patterning and proliferation by TGFbeta and WNT activity

scientific article published on 01 October 2004

Defects in GPI biosynthesis perturb Cripto signaling during forebrain development in two new mouse models of holoprosencephaly.

scientific article

Defects in Stratum Corneum Desquamation Are the Predominant Effect of Impaired ABCA12 Function in a Novel Mouse Model of Harlequin Ichthyosis

scientific article

Development of bat flight: morphologic and molecular evolution of bat wing digits

scientific article

Developmental biology. Legs to wings and back again.

scientific article published in April 1999

Diencephalic Size Is Restricted by a Novel Interplay Between GCN5 Acetyltransferase Activity and Retinoic Acid Signaling.

scientific article published on 2 February 2017

Disruption of Scale Development byDelta-1Misexpression ⬇️

scientific article published on March 1, 1998

Distinct roles of type I bone morphogenetic protein receptors in the formation and differentiation of cartilage ⬇️

scientific article published on September 1, 1997

Dlx genes integrate positive and negative signals during feather bud development.

scientific article published in January 2004

Dynamic behaviors of the non-neural ectoderm during mammalian cranial neural tube closure.

scientific article published on 22 June 2016

Editorial overview: developmental mechanisms, patterning and evolution.

scientific article published on 2 July 2014

Expression of a constitutively active type I BMP receptor using a retroviral vector promotes the development of adrenergic cells in neural crest cultures

scientific article published on 01 April 1998

Expression of slit‐2 and slit‐3 during chick development ⬇️

scientific article published on October 1, 2001

FGF-4 and BMP-2 have opposite effects on limb growth.

scientific article published on January 1993

FGF17b and FGF18 have different midbrain regulatory properties from FGF8b or activated FGF receptors ⬇️

scientific article published on November 5, 2003

Folic acid supplementation can adversely affect murine neural tube closure and embryonic survival.

scientific article

Forming and shaping the field of limb development: A tribute to Dr. John Saunders.

scientific article published in September 2017

Function of FGF-4 in limb development.

scientific article published on September 1994

Gefitinib selectively inhibits tumor cell migration in EGFR-amplified human glioblastoma ⬇️

scientific article published on June 7, 2013

Genetic contribution of retinoid-related genes to neural tube defects

scientific article published on 3 January 2018

Genetic, epigenetic, and environmental contributions to neural tube closure

scientific article

Grainyhead-like 2 downstream targets act to suppress epithelial-to-mesenchymal transition during neural tube closure.

scientific article published on 22 February 2016

Grainyhead-like 2 regulates neural tube closure and adhesion molecule expression during neural fold fusion

scientific journal article

Hedgehog signalling in the mouse requires intraflagellar transport proteins

scientific journal article

Homozygous WNT3 mutation causes tetra-amelia in a large consanguineous family

scientific article

Hopeful monsters and morphogens at the beach

scientific article published in November 2002

Identification and localization of DNA alteration in Chinese hamster ovary cell mutants (Urd-) defective in the first three enzymes of de novo pyrimidine synthesis

scientific article published on 01 July 1985

In toto live imaging of mouse morphogenesis and new insights into neural tube closure

scientific article

Interaction between the signaling molecules WNT7a and SHH during vertebrate limb development: dorsal signals regulate anteroposterior patterning.

scientific article

Interdigital webbing retention in bat wings illustrates genetic changes underlying amniote limb diversification

scientific article

LDL-receptor-related protein 4 is crucial for formation of the neuromuscular junction

scientific journal article

Limb mutants: what can they tell us about normal limb development?

scientific article published on August 1997

Lin28 promotes the proliferative capacity of neural progenitor cells in brain development

scientific article published on May 2015

MEMO1 drives cranial endochondral ossification and palatogenesis.

scientific article published on 30 December 2015

Mechanisms of tissue fusion during development.

scientific article published in May 2012

Methods in avian embryology experimental and molecular manipulation of the embryonic chick limb

scientific article published on January 2008

Microcephaly disease gene Wdr62 regulates mitotic progression of embryonic neural stem cells and brain size

scientific article published on 30 May 2014

Molecular mapping of albino deletions associated with early embryonic lethality in the mouse.

scientific article

Molecular signaling in intervertebral disk development.

scientific article published in September 2005

Morphogenetic movements in the neural plate and neural tube: mouse

scientific article

Mouse intraflagellar transport proteins regulate both the activator and repressor functions of Gli transcription factors

scientific journal article

Multiparametric image analysis of lung‐branching morphogenesis ⬇️

scientific article published on April 23, 2013

Novel α-tubulin mutation disrupts neural development and tubulin proteostasis

scientific article

Nubp1 is required for lung branching morphogenesis and distal progenitor cell survival in mice

scientific article

Partial cDNA sequence to a hamster gene corrects defect in Escherichia coli pyrB mutant

scientific article

Pattern formation: old models out on a limb.

scientific article

Peripheral nervous system defects in a mouse model for peroxisomal biogenesis disorders

scientific article

Phactr4 regulates directional migration of enteric neural crest through PP1, integrin signaling, and cofilin activity

scientific journal article

Phactr4 regulates neural tube and optic fissure closure by controlling PP1-, Rb-, and E2F1-regulated cell-cycle progression

scientific journal article

Phactr4: a new integrin modulator required for directional migration of enteric neural crest cells.

scientific article published on September 2012

Physical mapping of the albino-deletion complex in the mouse to localize alf/hsdr-1, a locus required for neonatal survival

scientific article published on 01 October 1992

Plasmid-based short-hairpin RNA interference in the chicken embryo.

scientific article published in June 2004

Potassium dependent rescue of a myopathy with core-like structures in mouse

scientific article published on 7 January 2015

Rectification of muscle and nerve deficits in paralyzed ryanodine receptor type 1 mutant embryos.

scientific article

Requirement for BMP signaling in interdigital apoptosis and scale formation.

scientific article

Scribble is required for normal epithelial cell-cell contacts and lumen morphogenesis in the mammalian lung.

scientific article published on 27 November 2012

Snx3 is important for mammalian neural tube closure via its role in canonical and non-canonical WNT signaling

scientific article published on 19 November 2020

The Hectd1 ubiquitin ligase is required for development of the head mesenchyme and neural tube closure

scientific journal article

The Ptch1(DL) mouse: a new model to study lambdoid craniosynostosis and basal cell nevus syndrome-associated skeletal defects

scientific article published on 30 August 2013

The coiled-coil domain containing protein CCDC40 is essential for motile cilia function and left-right axis formation

scientific article

The continuing challenge of understanding, preventing, and treating neural tube defects.

scientific article

The developmental reduction of the marsupial coracoid: a case study in Monodelphis domestica.

scientific article published in July 2010

The evolutionary and developmental basis of parallel reduction in mammalian zeugopod elements

scientific article published on 28 November 2006

The flatiron mutation in mouse ferroportin acts as a dominant negative to cause ferroportin disease

scientific article

The ubiquitin ligase mLin41 temporally promotes neural progenitor cell maintenance through FGF signaling

scientific journal article

Tissue morphogenesis and vascular stability require the Frem2 protein, product of the mouse myelencephalic blebs gene

scientific article

Using genomewide mutagenesis screens to identify the genes required for neural tube closure in the mouse

scientific article

Visualization of cartilage formation: insight into cellular properties of skeletal progenitors and chondrodysplasia syndromes.

scientific article published in June 2007

Zic2 is required for enteric nervous system development and neurite outgrowth: a mouse model of enteric hyperplasia and dysplasia.

scientific article published on 17 February 2013

Zinc deficiency causes neural tube defects through attenuation of p53 ubiquitylation

scientific article published on 13 December 2018

p38 and a p38-interacting protein are critical for downregulation of E-cadherin during mouse gastrulation

scientific article

List of works by Lee Niswander

A hypomorphic allele reveals an important role of inturned in mouse skeletal development

A mouse model for Meckel syndrome reveals Mks1 is required for ciliogenesis and Hedgehog signaling

A positive feedback loop coordinates growth and patterning in the vertebrate limb.

A unique missense allele of BAF155, a core BAF chromatin remodeling complex protein, causes neural tube closure defects in mice

ALC (adjacent to LMX1 in chick) is a novel dorsal limb mesenchyme marker

An explant muscle model to examine the refinement of the synaptic landscape

BMP Expression in Duck Interdigital Webbing: A Reanalysis

BMPs are required at two steps of limb chondrogenesis: formation of prechondrogenic condensations and their differentiation into chondrocytes

C2cd3 is required for cilia formation and Hedgehog signaling in mouse.

Canonical Wnt signaling negatively regulates branching morphogenesis of the lung and lacrimal gland.

Cell polarity pathways converge and extend to regulate neural tube closure.

Chromosome jumping from flanking markers defines the minimal region for alf/hsdr-1 within the albino-deletion complex

Coordinate regulation of neural tube patterning and proliferation by TGFbeta and WNT activity

Defects in GPI biosynthesis perturb Cripto signaling during forebrain development in two new mouse models of holoprosencephaly.

Defects in Stratum Corneum Desquamation Are the Predominant Effect of Impaired ABCA12 Function in a Novel Mouse Model of Harlequin Ichthyosis

Development of bat flight: morphologic and molecular evolution of bat wing digits

Developmental biology. Legs to wings and back again.

Diencephalic Size Is Restricted by a Novel Interplay Between GCN5 Acetyltransferase Activity and Retinoic Acid Signaling.

Disruption of Scale Development byDelta-1Misexpression ⬇️

Distinct roles of type I bone morphogenetic protein receptors in the formation and differentiation of cartilage ⬇️

Dlx genes integrate positive and negative signals during feather bud development.

Dynamic behaviors of the non-neural ectoderm during mammalian cranial neural tube closure.

Editorial overview: developmental mechanisms, patterning and evolution.

Expression of a constitutively active type I BMP receptor using a retroviral vector promotes the development of adrenergic cells in neural crest cultures

Expression of slit‐2 and slit‐3 during chick development ⬇️

FGF-4 and BMP-2 have opposite effects on limb growth.

FGF17b and FGF18 have different midbrain regulatory properties from FGF8b or activated FGF receptors ⬇️

Folic acid supplementation can adversely affect murine neural tube closure and embryonic survival.

Forming and shaping the field of limb development: A tribute to Dr. John Saunders.

Function of FGF-4 in limb development.

Gefitinib selectively inhibits tumor cell migration in EGFR-amplified human glioblastoma ⬇️

Genetic contribution of retinoid-related genes to neural tube defects

Genetic, epigenetic, and environmental contributions to neural tube closure

Grainyhead-like 2 downstream targets act to suppress epithelial-to-mesenchymal transition during neural tube closure.

Grainyhead-like 2 regulates neural tube closure and adhesion molecule expression during neural fold fusion

Hedgehog signalling in the mouse requires intraflagellar transport proteins

Homozygous WNT3 mutation causes tetra-amelia in a large consanguineous family

Hopeful monsters and morphogens at the beach

Identification and localization of DNA alteration in Chinese hamster ovary cell mutants (Urd-) defective in the first three enzymes of de novo pyrimidine synthesis

In toto live imaging of mouse morphogenesis and new insights into neural tube closure

Interaction between the signaling molecules WNT7a and SHH during vertebrate limb development: dorsal signals regulate anteroposterior patterning.

Interdigital webbing retention in bat wings illustrates genetic changes underlying amniote limb diversification

LDL-receptor-related protein 4 is crucial for formation of the neuromuscular junction

Limb mutants: what can they tell us about normal limb development?

Lin28 promotes the proliferative capacity of neural progenitor cells in brain development

MEMO1 drives cranial endochondral ossification and palatogenesis.

Mechanisms of tissue fusion during development.

Methods in avian embryology experimental and molecular manipulation of the embryonic chick limb

Microcephaly disease gene Wdr62 regulates mitotic progression of embryonic neural stem cells and brain size

Molecular mapping of albino deletions associated with early embryonic lethality in the mouse.

Molecular signaling in intervertebral disk development.

Morphogenetic movements in the neural plate and neural tube: mouse

Mouse intraflagellar transport proteins regulate both the activator and repressor functions of Gli transcription factors

Multiparametric image analysis of lung‐branching morphogenesis ⬇️

Novel α-tubulin mutation disrupts neural development and tubulin proteostasis

Nubp1 is required for lung branching morphogenesis and distal progenitor cell survival in mice

Partial cDNA sequence to a hamster gene corrects defect in Escherichia coli pyrB mutant

Pattern formation: old models out on a limb.

Peripheral nervous system defects in a mouse model for peroxisomal biogenesis disorders

Phactr4 regulates directional migration of enteric neural crest through PP1, integrin signaling, and cofilin activity

Phactr4 regulates neural tube and optic fissure closure by controlling PP1-, Rb-, and E2F1-regulated cell-cycle progression

Phactr4: a new integrin modulator required for directional migration of enteric neural crest cells.

Physical mapping of the albino-deletion complex in the mouse to localize alf/hsdr-1, a locus required for neonatal survival

Plasmid-based short-hairpin RNA interference in the chicken embryo.

Potassium dependent rescue of a myopathy with core-like structures in mouse

Rectification of muscle and nerve deficits in paralyzed ryanodine receptor type 1 mutant embryos.

Requirement for BMP signaling in interdigital apoptosis and scale formation.

Scribble is required for normal epithelial cell-cell contacts and lumen morphogenesis in the mammalian lung.

Snx3 is important for mammalian neural tube closure via its role in canonical and non-canonical WNT signaling

The Hectd1 ubiquitin ligase is required for development of the head mesenchyme and neural tube closure

The Ptch1(DL) mouse: a new model to study lambdoid craniosynostosis and basal cell nevus syndrome-associated skeletal defects

The coiled-coil domain containing protein CCDC40 is essential for motile cilia function and left-right axis formation

The continuing challenge of understanding, preventing, and treating neural tube defects.

The developmental reduction of the marsupial coracoid: a case study in Monodelphis domestica.

The evolutionary and developmental basis of parallel reduction in mammalian zeugopod elements

The flatiron mutation in mouse ferroportin acts as a dominant negative to cause ferroportin disease

The ubiquitin ligase mLin41 temporally promotes neural progenitor cell maintenance through FGF signaling

Tissue morphogenesis and vascular stability require the Frem2 protein, product of the mouse myelencephalic blebs gene

Using genomewide mutagenesis screens to identify the genes required for neural tube closure in the mouse