List of works by Giancarlo Castellano

A B-cell epigenetic signature defines three biologic subgroups of chronic lymphocytic leukemia with clinical impact.

scientific article published on 25 August 2014

Aberrant epigenome in iPSC-derived dopaminergic neurons from Parkinson's disease patients.

scientific article

Activation of mitogen- and stress-activated kinase 1 is required for proliferation of breast cancer cells in response to estrogens or progestins

scientific article published on 22 April 2013

Activation of phosphatidylcholine cycle enzymes in human epithelial ovarian cancer cells

scientific article

Activation of the osteopontin/matrix metalloproteinase-9 pathway correlates with prostate cancer progression.

scientific article

Androgen Receptor and Its Splicing Variant 7 Expression in Peripheral Blood Mononuclear Cells and in Circulating Tumor Cells in Metastatic Castration-Resistant Prostate Cancer

scientific article published on 14 January 2020

CCAAT/enhancer binding protein alpha (C/EBP(alpha))-induced transdifferentiation of pre-B cells into macrophages involves no overt retrodifferentiation.

scientific article

CDK2-dependent activation of PARP-1 is required for hormonal gene regulation in breast cancer cells.

scientific article

Cyclin D1 overexpression induces global transcriptional downregulation in lymphoid neoplasms

scientific article published on 20 August 2018

DNA methylation fingerprint of neuroblastoma reveals new biological and clinical insights

scientific article

DNA methylation fingerprint of neuroblastoma reveals new biological and clinical insights

scientific article published on 12 June 2015

Decoding the DNA Methylome of Mantle Cell Lymphoma in the Light of the Entire B Cell Lineage.

scientific article published on November 2016

Discovery of first-in-class reversible dual small molecule inhibitors against G9a and DNMTs in hematological malignancies

scientific article

Distinct structural transitions of chromatin topological domains correlate with coordinated hormone-induced gene regulation

scientific article published on October 2014

Epigenomic analysis detects widespread gene-body DNA hypomethylation in chronic lymphocytic leukemia.

scientific article published on 14 October 2012

Four enzymes cooperate to displace histone H1 during the first minute of hormonal gene activation

scientific article published on 29 March 2011

Human cutaneous melanomas lacking MITF and melanocyte differentiation antigens express a functional Axl receptor kinase.

scientific article

Integrated ligand-receptor bioinformatic and in vitro functional analysis identifies active TGFA/EGFR signaling loop in papillary thyroid carcinomas

scientific article

New potential ligand-receptor signaling loops in ovarian cancer identified in multiple gene expression studies

scientific article published on 06 November 2006

Non-coding recurrent mutations in chronic lymphocytic leukaemia

scientific article published in Nature

Nucleosome-driven transcription factor binding and gene regulation

scientific article published on 21 November 2012

Progesterone receptor induces bcl-x expression through intragenic binding sites favoring RNA polymerase II elongation

scientific article published on 2 May 2013

SOX11 promotes tumor angiogenesis through transcriptional regulation of PDGFA in mantle cell lymphoma.

scientific article published on 4 August 2014

SOX11 regulates PAX5 expression and blocks terminal B-cell differentiation in aggressive mantle cell lymphoma

scientific article published on 15 January 2013

The involvement of the transcription factor Yin Yang 1 in cancer development and progression.

scientific article published on 26 May 2009

The proliferative history shapes the DNA methylome of B-cell tumors and predicts clinical outcome

scientific article published on 02 November 2020

The reference epigenome and regulatory chromatin landscape of chronic lymphocytic leukemia

scientific article published on 21 May 2018

Transgene codon usage drives viral fitness and therapeutic efficacy in oncolytic adenoviruses

scientific article published on 26 April 2021

Tumor initiating cells: development and critical characterization of a model derived from the A431 carcinoma cell line forming spheres in suspension.

scientific article published on 15 March 2010

Tumor microenvironment in diffuse large B-cell lymphoma: Matrixmetalloproteinases activation is mediated by osteopontin overexpression

scientific article published on 14 September 2015

Variant HNF1 modulates epithelial plasticity of normal and transformed ovary cells.

scientific article published on December 2008

Whole-epigenome analysis in multiple myeloma reveals DNA hypermethylation of B cell-specific enhancers.

scientific article

Whole-genome DNA hyper-methylation in iPSC-derived dopaminergic neurons from Parkinson's disease patients

scientific article published on 23 July 2019

Whole-genome fingerprint of the DNA methylome during human B cell differentiation

scientific article

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