List of works - Bianca Plouffe

Angiotensin II pseudopeptides containing 1,3,5-trisubstituted benzene scaffolds with high AT2 receptor affinity

scientific article published on October 2005

Constitutive activities and inverse agonism in dopamine receptors

scientific article

Design, synthesis, and biological evaluation of the first selective nonpeptide AT2 receptor agonist.

scientific article

Discovery of G Protein-Biased Dopaminergics with a Pyrazolo[1,5-a]pyridine Substructure

scientific article

Distinct conformations of GPCR-β-arrestin complexes mediate desensitization, signaling, and endocytosis

scientific article

Emerging Role of Compartmentalized G Protein-Coupled Receptor Signaling in the Cardiovascular Field

scientific article published on 24 February 2020

Functional Analysis of Human D1 and D5 Dopaminergic G Protein-Coupled Receptors: Lessons from Mutagenesis of a Conserved Serine Residue in the Cytosolic End of Transmembrane Region 6 ⬇️

scientific article published on January 1, 2013

GPCR-G Protein-β-Arrestin Super-Complex Mediates Sustained G Protein Signaling

scientific article

Human MC4R variants affect endocytosis, trafficking and dimerization revealing multiple cellular mechanisms involved in weight regulation

scientific article published on 01 March 2021

In vitro irradiation of basement membrane enhances the invasiveness of breast cancer cells.

scientific article published on 6 November 2007

Manifold roles of β-arrestins in GPCR signaling elucidated with siRNA and CRISPR/Cas9

scientific article published on 25 September 2018

Mapping physiological G protein-coupled receptor signaling pathways reveals a role for receptor phosphorylation in airway contraction

scientific article (publication date: 19 April 2016)

New selective AT2 receptor ligands encompassing a gamma-turn mimetic replacing the amino acid residues 4-5 of angiotensin II act as agonists.

scientific article published in June 2005

Probing the constitutive activity among dopamine D1 and D5 receptors and their mutants

scientific article published on January 1, 2010

Purinergic Receptor Transactivation by the β2-Adrenergic Receptor Increases Intracellular Ca2+ in Nonexcitable Cells

scientific article

Selective angiotensin II AT(2) receptor agonists devoid of the imidazole ring system

scientific article

Selective angiotensin II AT(2) receptor agonists with reduced CYP 450 inhibition

scientific article

Selective angiotensin II AT2 receptor agonists: arylbenzylimidazole structure-activity relationships

scientific article published in November 2006

Short pseudopeptides containing turn scaffolds with high AT2 receptor affinity

scientific article published on 05 June 2006

The third intracellular loop of D1 and D5 dopaminergic receptors dictates their subtype-specific PKC-induced sensitization and desensitization in a receptor conformation-dependent manner.

scientific article published on 26 August 2011

Translating biased signaling in the ghrelin receptor system into differential in vivo functions

article published in the Proceedings of the National Academy of Sciences of the United States of America

List of works by Bianca Plouffe

Angiotensin II pseudopeptides containing 1,3,5-trisubstituted benzene scaffolds with high AT2 receptor affinity

Constitutive activities and inverse agonism in dopamine receptors

Design, synthesis, and biological evaluation of the first selective nonpeptide AT2 receptor agonist.

Discovery of G Protein-Biased Dopaminergics with a Pyrazolo[1,5-a]pyridine Substructure

Distinct conformations of GPCR-β-arrestin complexes mediate desensitization, signaling, and endocytosis

Emerging Role of Compartmentalized G Protein-Coupled Receptor Signaling in the Cardiovascular Field

Functional Analysis of Human D1 and D5 Dopaminergic G Protein-Coupled Receptors: Lessons from Mutagenesis of a Conserved Serine Residue in the Cytosolic End of Transmembrane Region 6 ⬇️

GPCR-G Protein-β-Arrestin Super-Complex Mediates Sustained G Protein Signaling

Human MC4R variants affect endocytosis, trafficking and dimerization revealing multiple cellular mechanisms involved in weight regulation

In vitro irradiation of basement membrane enhances the invasiveness of breast cancer cells.

Manifold roles of β-arrestins in GPCR signaling elucidated with siRNA and CRISPR/Cas9

Mapping physiological G protein-coupled receptor signaling pathways reveals a role for receptor phosphorylation in airway contraction

New selective AT2 receptor ligands encompassing a gamma-turn mimetic replacing the amino acid residues 4-5 of angiotensin II act as agonists.

Probing the constitutive activity among dopamine D1 and D5 receptors and their mutants

Purinergic Receptor Transactivation by the β2-Adrenergic Receptor Increases Intracellular Ca2+ in Nonexcitable Cells

Selective angiotensin II AT(2) receptor agonists devoid of the imidazole ring system

Selective angiotensin II AT(2) receptor agonists with reduced CYP 450 inhibition

Selective angiotensin II AT2 receptor agonists: arylbenzylimidazole structure-activity relationships

Short pseudopeptides containing turn scaffolds with high AT2 receptor affinity

The third intracellular loop of D1 and D5 dopaminergic receptors dictates their subtype-specific PKC-induced sensitization and desensitization in a receptor conformation-dependent manner.

Translating biased signaling in the ghrelin receptor system into differential in vivo functions

Type 2 diabetes–associated variants of the MT2melatonin receptor affect distinct modes of signaling