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List of works by Joanna Wietrzyk

1-methylnicotinamide and its structural analog 1,4-dimethylpyridine for the prevention of cancer metastasis

scientific article published on 13 July 2016

3,4-dimethoxybenzyl isothiocyanate enhances doxorubicin efficacy in LoVoDX doxorubicin-resistant colon cancer and attenuates its toxicity in vivo

scientific article published on 04 June 2019

3D Raman imaging of systemic endothelial dysfunction in the murine model of metastatic breast cancer

scientific article (publication date: May 2016)

4-Pyridone-3-carboxamide-1-β-D-ribonucleoside (4PYR)-A Novel Oncometabolite Modulating Cancer-Endothelial Interactions in Breast Cancer Metastasis

scientific article published on 21 May 2022

A novel canine B-cell leukaemia cell line. Establishment, characterisation and sensitivity to chemotherapeutics

scientific article published on 9 August 2016

Acetate platinum(II) compound with 5,7-ditertbutyl-1,2,4-triazolo[1,5-a]pyrimidine that overcomes cisplatin resistance: structural characterization, in vitro cytotoxicity, and kinetic studies

scientific article

Activity of bacteriophages in murine tumor models depends on the route of phage administration.

scientific article published on January 2005

Acyloxymethyl esters of isophosphoramide mustard as new anticancer prodrugs

scientific article published on May 2013

Alterations in NO- and PGI2- dependent function in aorta in the orthotopic murine model of metastatic 4T1 breast cancer: relationship with pulmonary endothelial dysfunction and systemic inflammation.

scientific article published on 22 May 2018

Aminophosphinates against Helicobacter pylori ureolysis-Biochemical and whole-cell inhibition characteristics.

scientific article

An efficient synthesis of indolo[2,3-b]quinoline guanidine derivatives with their in vitro and in vivo study

scientific article published on 5 September 2017

Anti-proliferative activity of Monensin and its tertiary amide derivatives

scientific article published on 28 August 2015

Antiangiogenic and antitumour effects in vivo of genistein applied alone or combined with cyclophosphamide.

scientific article published in November 2001

Antiangiogenic cancer treatment: The great discovery and greater complexity (Review).

scientific article published on 26 September 2016

Anticancer activity of bacteriophage T4 and its mutant HAP1 in mouse experimental tumour models.

scientific article published in November 2004

Anticancer activity of the Uncaria tomentosa (Willd.) DC. preparations with different oxindole alkaloid composition

scientific article published on 25 June 2010

Antioxidant and antiproliferative activity of glycosides obtained by biotransformation of xanthohumol.

scientific article published on 15 February 2013

Antiproliferative Activity and Molecular Docking of Novel Double-Modified Colchicine Derivatives

scientific article published on 01 November 2018

Antiproliferative Activity and in Vivo Toxicity of Double-Point Modified Analogs of 1,25-Dihydroxyergocalciferol

scientific article

Antiproliferative Activity of Polyether Antibiotic--Cinchona Alkaloid Conjugates Obtained via Click Chemistry

scientific article published on 10 February 2015

Antiproliferative activity of ester derivatives of monensin A at the C-1 and C-26 positions

scientific article published on 21 July 2019

Antiproliferative activity of salinomycin and its derivatives

scientific article

Antitumor activity of bacteriophages in murine experimental cancer models caused possibly by inhibition of beta3 integrin signaling pathway

scientific article published on 01 January 2004

Antitumor activity of mannan-methotrexate conjugate in vitro and in vivo

scientific article published on January 2007

Antitumor effect of combined treatment of mice with cytostatic agents and bacteriophage T4.

scientific article

Antitumor effect of electrochemical therapy on transplantable mouse cancers

scientific article published on 01 May 2000

Antitumor properties of (5E,7E) analogs of vitamin D3.

scientific article published on 12 March 2010

Antitumor properties of diastereomeric and geometric analogs of vitamin D3.

scientific article published on April 2007

Antitumour and antimetastatic effect of genistein alone or combined with cyclophosphamide in mice transplanted with various tumours depends on the route of tumour transplantation

scientific article published on 01 March 2000

Application of TLC to Evaluate the Lipophilicity of Newly Synthesized Betulin Derivatives

scientific article published on 15 January 2020

Atypical calcium coordination number: Physicochemical study, cytotoxicity, DFT calculations and in silico pharmacokinetic characteristics of calcium caffeates

scientific article published on 24 May 2009

BSG (CD147) Serum Level and Genetic Variants Are Associated with Overall Survival in Acute Myeloid Leukaemia

scientific article published on 10 January 2022

Bacteriophages displaying anticancer peptides in combined antibacterial and anticancer treatment.

scientific article published on January 2014

Biaryl Sulfonamides Based on the 2-Azabicycloalkane Skeleton-Synthesis and Antiproliferative Activity

scientific article published on 06 November 2020

Biological Activity and In Silico Study of 3-Modified Derivatives of Betulin and Betulinic Aldehyde ⬇️

scientific article published on 19 March 2019

Biological activity in vitro of side-chain modified analogues of calcitriol

scientific article published on 01 May 2000

Biological activity of doubly modified salinomycin analogs - Evaluation in vitro and ex vivo

scientific article published on 10 July 2018

Biological effects of aromatic bis[aminomethylidenebis(phosphonic)] acids in osteoclast precursors in vitro

scientific article published on 28 August 2019

Biological evaluation of omega-(dialkylamino)alkyl derivatives of 6H-indolo[2,3-b]quinoline--novel cytotoxic DNA topoisomerase II inhibitors.

scientific article

Biological properties of new derivatives of daunorubicin.

scientific article published on March 2007

Bivalent polyether ionophores: Synthesis and biological evaluation of C 2 -symmetric salinomycin dimers

Breast cancer pulmonary metastasis is increased in mice undertaking spontaneous physical training in the running wheel; a call for revising beneficial effects of exercise on cancer progression

scientific article published on September 2017

Calcitriol Analogues Decrease Lung Metastasis but Impair Bone Metabolism in Aged Ovariectomized Mice Bearing 4T1 Mammary Gland Tumours

scientific article published on 01 October 2019

Calcitriol and Its Analogs Establish the Immunosuppressive Microenvironment That Drives Metastasis in 4T1 Mouse Mammary Gland Cancer

scientific article published on 20 July 2018

Calcitriol in the Presence of Conditioned Media from Metastatic Breast Cancer Cells Enhances Ex Vivo Polarization of M2 Alternative Murine Bone Marrow-Derived Macrophages

scientific article published on 23 November 2020

Cell density-dependent cytological stage profile and its application for a screen of cytostatic agents active towards Leukemic Stem Cells

scientific article published on 12 February 2018

Clopidogrel in a combined therapy with anticancer drugs-effect on tumor growth, metastasis, and treatment toxicity: Studies in animal models

scientific article published on 5 December 2017

Combination Therapy with DETA/NO and Clopidogrel Inhibits Metastasis in Murine Mammary Gland Cancer Models via Improved Vasoprotection

scientific article published on 04 October 2018

Combined colonic cancer treatment with vitamin D analogs and irinotecan or oxaliplatin.

scientific article published on February 2013

Correlation between VDR expression and antiproliferative activity of vitamin D3 compounds in combination with cytostatics.

scientific article

Cyclo(Pro-DOPA), a third identified bioactive metabolite produced by Streptomyces sp. 8812.

scientific article published on 26 April 2018

Cytotoxic and antitumor effect of fibrinogen-methotrexate conjugate

scientific article published on 01 February 2000

Cytotoxic malonate platinum(II) complexes with 1,2,4-triazolo[1,5-a]pyrimidine derivatives: structural characterization and mechanism of the suppression of tumor cell growth.

scientific article published on 19 August 2014

Dehalogenation Activity of Selected Fungi Toward δ-Iodo-γ-Lactone Derived from trans,trans-Farnesol

scientific article published on 29 February 2016

Design, Synthesis, and Evaluation of ω-(Isothiocyanato)alkylphosphinates and Phosphine Oxides as Antiproliferative Agents

scientific article published on 24 November 2017

Design, synthesis, and biological evaluation of artemisinin-indoloquinoline hybrids as potent antiproliferative agents.

scientific article published on 18 November 2014

Design, synthesis, and in vitro cancer cell growth inhibition evaluation and antimalarial testing of trioxanes installed in cyclic 2-enoate substructures.

scientific article published on 13 August 2013

De‑O‑acylated lipooligosaccharide of E. coli B reduces the number of metastatic foci via downregulation of myeloid cell activity

scientific article published on 08 November 2019

Differences in Antiproliferative Activity Between Salinomycin-AZT Conjugates Obtained via 'Click' and Esterification Reactions.

scientific article published on 23 August 2016

Differential Impact of Calcitriol and Its Analogs on Tumor Stroma in Young and Aged Ovariectomized Mice Bearing 4T1 Mammary Gland Cancer

scientific article published on 02 September 2020

Differential response of lung cancer cell lines to vitamin D derivatives depending on EGFR, KRAS, p53 mutation status and VDR polymorphism

scientific article published on 18 July 2019

Discovering simple phenylboronic acid and benzoxaborole derivatives for experimental oncology - phase cycle-specific inducers of apoptosis in A2780 ovarian cancer cells.

scientific article

Discovery of New 3,3-Diethylazetidine-2,4-dione Based Thiazoles as Nanomolar Human Neutrophil Elastase Inhibitors with Broad-Spectrum Antiproliferative Activity

scientific article published on 8 July 2022

Discovery of tropinone-thiazole derivatives as potent caspase 3/7 activators, and noncompetitive tyrosinase inhibitors with high antiproliferative activity: Rational design, one-pot tricomponent synthesis, and lipophilicity determination

scientific article published on 04 May 2019

Divergent Effect of Tacalcitol (PRI-2191) on Th17 Cells in 4T1 Tumor Bearing Young and Old Ovariectomized Mice

scientific article published on 09 March 2020

Dual antiplatelet therapy with clopidogrel and aspirin increases mortality in 4T1 metastatic breast cancer-bearing mice by inducing vascular mimicry in primary tumour.

scientific article

EGFR-targeted immunoliposomes as a selective delivery system of simvastatin, with potential use in treatment of triple-negative breast cancers

scientific article published on 07 August 2019

Effect of structural modifications of anthracyclines on the ability to overcome drug resistance of cancer cells

scientific article published on May 2006

Effect of the dichloro-substitution on antiproliferative activity of phthalimide-thiazole derivatives. Rational design, synthesis, elastase, caspase 3/7, and EGFR tyrosine kinase activity and molecular modeling study

scientific article published in May 2021

Efficient glycosylation of natural Danshensu and its enantiomer by sugar and 2-deoxy sugar donors.

scientific article published on 23 February 2018

Efficient human breast cancer xenograft regression after a single treatment with a novel liposomal formulation of epirubicin prepared using the EDTA ion gradient method

scientific article (publication date: 2014)

Endothelium and cancer metastasis: Perspectives for antimetastatic therapy.

scientific article published on 02 June 2015

Freeze-drying of plant tissue containing HBV surface antigen for the oral vaccine against hepatitis B.

scientific article published on 12 October 2014

Front Cover: New Human Islet Amyloid Polypeptide Fragments Susceptible to Aggregation (C&B 9/2020)

scientific article published in 2020

Fungal metabolites of xanthohumol with potent antiproliferative activity on human cancer cell lines in vitro ⬇️

scientific article published on February 4, 2013

GABA level and GAD activity in human and mouse normal and neoplastic mammary gland

scientific article published on 01 June 1999

Genistein alone or combined with cyclophosphamide may stimulate 16/C transplantable mouse mammary cancer growth.

scientific article published on 26 October 2004

Genistein: a soy isoflavone revealing a pleiotropic mechanism of action - clinical implications in the treatment and prevention of cancer

scientific article published on 27 February 2004

HSAB principle and nickel(II) ion reactivity towards 1-methyhydantoin

scientific article published in August 2011

Heparin-binding copolymer reverses effects of unfractionated heparin, enoxaparin, and fondaparinux in rats and mice

scientific article published on 5 July 2016

Heterogeneity of telomerase reverse transcriptase mutation and expression, telomerase activity and telomere length across human cancer cell lines cultured in vitro

scientific article published on 21 September 2020

Highly Cancer Selective Antiproliferative Activity of Natural Prenylated Flavonoids

scientific article published on 09 November 2018

Hoc protein regulates the biological effects of T4 phage in mammals

scientific article published on 10 February 2007

Hydroxyethyl starch as an effective methotrexate carrier in anticancer therapy

scientific article

Improved HDAC Inhibition, Stronger Cytotoxic Effect and Higher Selectivity against Leukemias and Lymphomas of Novel, Tricyclic Vorinostat Analogues

scientific article published on 26 August 2021

In search of new anticancer drug – Dimethylsulfoxide ruthenium(III) complex with bulky triazolopyrimidine derivative and preliminary studies towards understanding the mode of action

scientific article published in February 2018

Influence of amide versus ester linkages on the anticancer properties of the new flavone-biotin conjugates

scientific article published on 01 July 2019

Influence of bacteriophage preparations on migration of HL-60 leukemia cells in vitro

scientific article published in April 2013

Influence of the structure of new anthracycline antibiotics on their biological properties.

scientific article published on May 2005

Inhibitors of neoangiogenesis in antineoplastic therapy

scientific article published on 01 January 2001

Insulin enhancement of the antitumor activity of chemotherapeutic agents in colorectal cancer is linked with downregulating PIK3CA and GRB2

scientific article published on 12 November 2019

Investigating the antiproliferative activity of quinoline-5,8-diones and styrylquinolinecarboxylic acids on tumor cell lines.

scientific article

Investigation of lipophilicity of anticancer-active thioquinoline derivatives

scientific article published in February 2007

Isophosphoramide mustard analogues as prodrugs for anticancer gene-directed enzyme-prodrug therapy (GDEPT).

scientific article

Isoprenoid-phospholipid conjugates as potential therapeutic agents: Synthesis, characterization and antiproliferative studies

scientific article

Magnesium deficiency inhibits primary tumor growth but favors metastasis in mice

scientific article published on 01 December 2004

Metastatic potential and saccharide antigens expression of human colon cancer cells xenotransplanted into athymic nude mice

scientific article published on 01 January 1998

Metastatic potential of human CX-1 colon adenocarcinoma cells is dependent on the expression of sialosyl Le(a) antigen

scientific article published on 01 November 1998

Metastatic potential of human uroepithelial cancer cells is not dependent on their adhesion to E-selectin

scientific article published on 01 March 2000

Methotrexate and epirubicin conjugates as potential antitumor drugs.

scientific article published on 30 July 2017

Methoxy- and methyl-, methoxy-5,6,11-trimethyl-6H-indolo [2,3-b]quinolinium derivatives as novel cytotoxic agents and DNA topoisomerase II inhibitors

scientific article published on 01 July 1998

Microbial conversion of methyl- and methoxy- substituted derivatives of 5H-indolo[2,3-b]quinoline as a method of developing novel cytotoxic agents

scientific article published on 01 July 1999

Microbial transformation of (+)-nootkatone and the antiproliferative activity of its metabolites

scientific article published on 4 March 2011

Molecular basis for the DNA damage induction and anticancer activity of asymmetrically substituted anthrapyridazone PDZ-7.

scientific article published on 10 October 2017

Molecular docking studies, biological and toxicity evaluation of dihydroisoquinoline derivatives as potential anticancer agents.

scientific article published on 29 August 2016

Mononuclear copper(II) nitrato complexes with methyl-substituted 4-nitropyridine N-oxide. Physicochemical and cytotoxic characteristics

scientific article

Multinuclear NMR spectroscopy and antitumor activity of novel platinum(II) complexes with 5,7-disubstituted-1,2,4-triazolo[1,5-a]pyrimidines

scientific article published on January 2004

N-Arylaminomethylenebisphosphonates Bearing Fluorine Atoms: Synthesis and Antiosteoporotic Activity

N-Methylated Analogs of hIAPP Fragments 18-22, 23-27, 33-37 Inhibit Aggregation of the Amyloidogenic Core of the Hormone

scientific article published on 17 December 2020

New Series of Double-Modified Colchicine Derivatives: Synthesis, Cytotoxic Effect and Molecular Docking

scientific article published on 02 August 2020

New acetylenic derivatives of betulin and betulone, synthesis and cytotoxic activity

scientific article

New analogues of laminin active fragment YIGSR: synthesis and biological activity in vitro and in vivo.

scientific article published on May 2004

New derivatives of 11-methyl-6-[2-(dimethylamino)ethyl]-6H-indolo[2,3-b]quinoline as cytotoxic DNA topoisomerase II inhibitors.

scientific article published on 15 August 2012

New human Islet Amyloid Polypeptide fragments susceptible to aggregation

scientific article published on 02 September 2020

New insights into the possible role of bacteriophages in host defense and disease

scientific article

New mono- and dinuclear complexes of 7-azaindole-3-carboxaldehyde with palladium(II): crystal structure, IR and Raman spectra, DFT calculations and in vitro antiproliferative activity

New phosphate derivatives of betulin as anticancer agents: Synthesis, crystal structure, and molecular docking study

scientific article published on 22 March 2019

Nitric oxide deficiency and endothelial-mesenchymal transition of pulmonary endothelium in the progression of 4T1 metastatic breast cancer in mice

Novel (S)-1,3,4,12a-tetrahydropyrazino[2,1-c][1,4]benzodiazepine-6,12(2H,11H)-dione derivatives: Selective inhibition of MV-4-11 biphenotypic B myelomonocytic leukemia cells' growth is accompanied by reactive oxygen species overproduction and apopto

scientific article published on 27 January 2018

Novel Ru(III), Rh(III), Pd(II) and Pt(II) complexes with ligands incorporating azole and pyrimidine rings. I. Antiproliferative activity in vitro

scientific article published on 01 January 2000

Novel Vorinostat Analogues with Improved HDAC Inhibition, Stronger Cytotoxic Effect and Higher Selectivity Against Leukemias and Lymphomas

scientific article published on 11 May 2021

Novel genistein derivatives induce cell death and cell cycle arrest through different mechanisms

scientific article published on January 2013

Novel phosphonate analogs of sulforaphane: Synthesis, in vitro and in vivo anticancer activity.

scientific article

Octahydroquinoxalin-2(1H)-One-Based Aminophosphonic Acids and Their Derivatives-Biological Activity Towards Cancer Cells

scientific article published on 22 May 2020

One-pot synthesis and antiproliferative activity of novel double-modified derivatives of the polyether ionophore monensin A

scientific article published on 18 May 2018

One-pot synthesis and cytotoxicity studies of new Mannich base derivatives of polyether antibiotic--lasalocid acid.

scientific article published on 26 July 2013

One-pot synthesis of new (1,3-thiazolo[5,4-b]pyridin-2-yl)benzenediols and their antiproliferative activities against human cancer cell lines

scientific article published on January 2012

Oral Administration of Polymyxin B Modulates the Activity of Lipooligosaccharide E. coli B against Lung Metastases in Murine Tumor Models

scientific article published in February 2016

Organotin Compound Derived from 3-Hydroxy-2-formylpyridine Semicarbazone: Synthesis, Crystal Structure, and Antiproliferative Activity

scientific article

Oxazolinodoxorubicin - a promising new anthracycline.

scientific article

Phosphate prodrugs of isophosphoramide mustard.

scientific article published in March 2003

Phosphorus-containing isothiocyanate-derived mercapturic acids as a useful alternative for parental isothiocyanates in experimental oncology

scientific article published on 20 June 2018

Photoinduced Skeletal Rearrangement of <i>N</i>-Substituted Colchicine Derivatives

scientific article published on 22 December 2020

Phytoestrogens in cancer prevention and therapy--mechanisms of their biological activity.

scientific article

Plant lyophilisate carrying S-HBsAg as an oral booster vaccine against HBV

scientific article published on 07 September 2018

Potent covalent inhibitors of bacterial urease identified by activity-reactivity profiling.

scientific article published on 12 February 2017

Preliminary studies on application of library of artificial receptors for differentiation of metabolites in urine of healthy and cancer bearing mice

scientific article published on November 2014

Protein Disulphide Isomerase A1 Is Involved in the Regulation of Breast Cancer Cell Adhesion and Transmigration via Lung Microvascular Endothelial Cells

scientific article published on 02 October 2020

Rapid biochemical profiling of endothelial dysfunction in diabetes, hypertension and cancer metastasis by hierarchical cluster analysis of Raman spectra

Rational design of dicarboxylato platinum(II) complexes with purine-mimetic ligands as novel anticancer agents.

scientific article published on 4 April 2017

Reaction of 3-Amino-1,2,4-Triazole with Diethyl Phosphite and Triethyl Orthoformate: Acid-Base Properties and Antiosteoporotic Activities of the Products.

scientific article published on 8 February 2017

Relationship between Telomere Length, <i>TERT</i> Genetic Variability and <i>TERT</i>, <i>TP53</i>, <i>SP1</i>, <i>MYC</i> Gene Co-Expression in the Clinicopathological Profile of Breast Cancer

scientific article published on 05 May 2022

Retinol-Binding Protein 4 Accelerates Metastatic Spread and Increases Impairment of Blood Flow in Mouse Mammary Gland Tumors

scientific article published on 07 March 2020

Robust oil-core nanocapsules with hyaluronate-based shells as promising nanovehicles for lipophilic compounds.

scientific article published on 27 November 2017

Ruthenium(II) and Iridium(III) Complexes as Tested Materials for New Anticancer Agents

scientific article published on 07 August 2020

SYNTHESIS AND BIOLOGICAL ACTIVITY OF NOVEL 6-PHENYL-1H-PYRROLO[3,4-c]PYRIDINE-1,3-DIONE DERIVATIVES.

scientific article published in March 2017

SYNTHESIS AND BIOLOGICAL ACTIVITY OF NOVEL N,N-CYCLIC-2,4-DIHYDROXYTHIOBENZAMIDE DERIVATIVES.

scientific article published on September 2015

SYNTHESIS AND CYTOTOXIC ACTIVITY OF NEW 5H-INDOLO[2,3-B]QUINOLINE O-AMINOGLYCOSIDES.

scientific article published on May 2016

SYNTHESIS AND IN VITRO ANTIPROLIFERATIVE ACTIVITY OF NOVEL 2-ARYLIDENEAMINOBENZIMIDAZOLE DERIVATIVES.

scientific article published on September 2015

Searching for new derivatives of neocryptolepine: synthesis, antiproliferative, antimicrobial and antifungal activities.

scientific article published on 20 March 2014

Silver(I) complexes with hydantoins and allantoin: synthesis, crystal and molecular structure, cytotoxicity and pharmacokinetics

scientific article

Similarities and differences in d6 low-spin ruthenium, rhodium and iridium half-sandwich complexes: synthesis, structure, cytotoxicity and interaction with biological targets

scientific article published on 21 May 2019

Simple phosphonic inhibitors of human neutrophil elastase.

scientific article published on 22 January 2011

Spectrofluorimetric and Computational Investigation of New Phthalimide Derivatives towards Human Neutrophil Elastase Inhibition and Antiproliferative Activity

scientific article published on 21 December 2022

Spectroscopic, structural and anticancer activity studies of (−)-cytisine halogenated N-benzyl derivatives

scientific article published in January 2019

Steroid hormone calcitriol and its analog tacalcitol inhibit miR-125b expression in a human breast cancer MCF-7 cell line

scientific article published on 29 November 2018

Structural Modifications of Nature-Inspired Indoloquinolines: A Mini Review of Their Potential Antiproliferative Activity

scientific article published on 05 June 2019

Structural factors affecting cytotoxic activity of (E)-1-(Benzo[d ][1,3]oxathiol-6-yl)-3-phenylprop-2-en-1-one derivatives.

scientific article published on 28 February 2014

Structure-Antioxidant-Antiproliferative Activity Relationships of Natural C7 and C7-C8 Hydroxylated Flavones and Flavanones

scientific article published on 07 July 2019

Structure-cytotoxicity relationship for different types of mononuclear platinum(II) complexes with 5,7-ditertbutyl-1,2,4-triazolo[1,5-a]pyrimidine.

scientific article published on 23 May 2012

Structure–activity relationship disturbed by a solvolytic process: Study on the [Cu(II)-4-nitropyridine N-oxide derivative] system

scientific article published in February 2013

Syntheses and antiproliferative activities of novel phosphatidylcholines containing dehydroepiandrosterone moieties

scientific article published on 4 January 2017

Synthesis and Anticancer Activity of Dimeric Polyether Ionophores

scientific article published on 12 July 2020

Synthesis and Antiproliferative Activity of Minor Hops Prenylflavonoids and New Insights on Prenyl Group Cyclization.

scientific article published on 28 March 2018

Synthesis and Antiproliferative Activity of Silybin Conjugates with Salinomycin and Monensin.

scientific article published on 8 June 2015

Synthesis and Antiproliferative Screening Of Novel Analogs of Regioselectively Demethylated Colchicine and Thiocolchicine

scientific article published on 05 March 2020

Synthesis and Biological Activity of Diastereomeric and Geometric Analogs of Calcipotriol, PRI-2202 and PRI-2205, Against Human HL-60 Leukemia and MCF-7 Breast Cancer Cells

scientific article published on 31 October 2013

Synthesis and Biological Evaluation of Novel Phosphatidylcholine Analogues Containing Monoterpene Acids as Potent Antiproliferative Agents

scientific article

Synthesis and Biological Evaluation of Novel Triple-Modified Colchicine Derivatives as Potent Tubulin-Targeting Anticancer Agents ⬇️

scientific article published on 19 November 2018

Synthesis and In Vitro Antiproliferative Activity of 11-Substituted Neocryptolepines with a Branched ω-Aminoalkylamino Chain.

scientific article published on 12 November 2017

Synthesis and Structure of Novel Copper(II) Complexes with N,O- or N,N-Donors as Radical Scavengers and a Functional Model of the Active Sites in Metalloenzymes

scientific article published on 6 July 2021

Synthesis and anticancer activity of new 1-substituted-6H-pyrido[4,3-b]carbazole derivatives.

scientific article

Synthesis and antiproliferative activity in vitro of 2-aminobenzimidazole derivatives

scientific article published on February 2004

Synthesis and antiproliferative activity in vitro of new 2-, 3- or 4-substituted pyrido[2',3':3,4]pyrazolo[1, 5-a]pyrimidines.

scientific article published on May 2006

Synthesis and antiproliferative activity in vitro of new 2-thioxoimidazo[4,5-B]pyridine derivatives

scientific article

Synthesis and antiproliferative activity in vitro of new 3-substituted aminoisoxazolo[5,4-b]pyridines

scientific article published on July 2003

Synthesis and antiproliferative activity in vitro of new 3-substituted aminopyrazolo[3,4-b]pyridines

scientific article published in May 2002

Synthesis and antiproliferative activity in vitro of new propargyl thioquinolines.

scientific article

Synthesis and antiproliferative activity in vitro of new pyrido[1,4-b]diazepine derivatives and imidazo[4,5-b]pyridine.

scientific article published on May 2011

Synthesis and antiproliferative activity in vitro of novel (2-butynyl)thioquinolines.

scientific article

Synthesis and antiproliferative activity of new bioconjugates of Salinomycin with amino acid esters

scientific article published on 2 July 2015

Synthesis and antiproliferative activity of novel α- and β-dialkoxyphosphoryl isothiocyanates.

scientific article published on 6 June 2011

Synthesis and antiproliferative activity of side-chain unsaturated and homologated analogs of 1,25-dihydroxyvitamin D(2). (24E)-(1S)-24-Dehydro-24a-homo-1,25-dihydroxyergocalciferol and congeners.

scientific article published on August 2002

Synthesis and antiproliferative activity of some N'-substituted 2,4-dihydroxybenzothiohydrazides

scientific article published on 26 July 2016

Synthesis and antitumour activity of stereoisomers of 4-hydroperoxy derivatives of ifosfamide and its bromo analogue.

scientific article

Synthesis and biological activity of diisothiocyanate-derived mercapturic acids.

scientific article published on 27 November 2015

Synthesis and biological activity of salinomycin conjugates with floxuridine.

scientific article

Synthesis and biological evaluation of 4'-O-acetyl-isoxanthohumol and its analogues as antioxidant and antiproliferative agents.

scientific article

Synthesis and biological evaluation of acyl derivatives of hydroxyflavones as potent antiproliferative agents against drug resistance cell lines.

scientific article published on 8 November 2017

Synthesis and biological evaluation of new amino acid and dipeptide derivatives of neocryptolepine as anticancer agents.

scientific article published on 18 May 2012

Synthesis and biological properties of oxazolinodaunorubicin--a new derivative of daunorubicin with a modified daunosamine moiety.

scientific article published on 28 August 2009

Synthesis and cytotoxic activity of new betulin and betulinic acid esters with conjugated linoleic acid (CLA).

scientific article published on April 2013

Synthesis and cytotoxicity studies of bifunctional hybrids of nitrogen mustards with potential enzymes inhibitors based on melamine framework

scientific article published on 08 September 2011

Synthesis and electrochemical, spectral, and biological evaluation of novel 9,10-anthraquinone derivatives containing piperidine unit as potent antiproliferative agents

scholarly article by Paweł Niedziałkowski et al published January 2019 in Journal of Molecular Structure

Synthesis and in vitro antiproliferative activity of new 1,3-(oxytetraethylenoxy)-cyclotriphosphazene derivatives

scientific article

Synthesis and in vitro antiproliferative activity of new 11-aminoalkylamino-substituted 5H- and 6H-indolo[2,3-b]quinolines; structure-activity relationships of neocryptolepines and 6-methyl congeners.

scientific article

Synthesis and in vitro antiproliferative activity of new 11-aminoalkylamino-substituted chromeno[2,3-b]indoles.

scientific article

Synthesis and in vitro antiproliferative activity of novel (4-chloro- and 4-acyloxy-2-butynyl)thioquinolines.

scientific article

Synthesis and in vitro antiproliferative activity of thiazole-based nitrogen mustards: the hydrogen bonding interaction between model systems and nucleobases

scientific article

Synthesis and in vitro cytotoxic effect of 6-amino-substituted 11H- and 11Me-indolo[3,2-c]quinolines.

scientific article published on 19 March 2014

Synthesis and structure-activity relationship analysis of new olivacine derivatives.

scientific article published on September 2010

Synthesis of 5,6-dimethyl-9-methoxy-1-phenyl-6H-pyrido[4,3-b]carbazole derivatives and their cytotoxic activity.

scientific article published on November 2005

Synthesis of 6-substituted 6H-indolo[2,3-b]quinolines as novel cytotoxic agents and topoisomerase II inhibitors.

scientific article published in May 2002

Synthesis of Platinum(II) Complexes with Some 1-Methylnitropyrazoles and In Vitro Research on Their Cytotoxic Activity

scientific article published on 28 November 2020

Synthesis of a natural gamma-butyrolactone from nerylacetone by Acremonium roseum and Fusarium oxysporum cultures.

scientific article published on March 2011

Synthesis of new 1-phenyl-6H-pyrido[4,3-b]carbazole derivatives with potential cytostatic activity

scientific article published on January 2011

Synthesis of new derivatives of 4-methyl-5-ethoxalyl-1H-2,3,4,5- tetrahydro-1,5-benzodiazepin-2-one and their psychotropic and anti-proliferative activities

scientific article published on 01 September 1998

Synthesis, Antiproliferative Activity and Molecular Docking Studies of Novel Doubly Modified Colchicine Amides and Sulfonamides as Anticancer Agents

scientific article published on 14 April 2020

Synthesis, CYP24A1-Dependent Metabolism and Antiproliferative Potential against Colorectal Cancer Cells of 1,25-Dihydroxyvitamin D2 Derivatives Modified at the Side Chain and the A-Ring

scientific article published on 18 January 2020

Synthesis, Characterization and Antiproliferative Activity of the Co(II), Ni(II), Cu(II), Pd(II) and Pt(II) Complexes of 2-(4-Thiazolyl)Benzimidazole (Thiabendazole).

scientific article published in January 2001

Synthesis, Characterization, and In Vitro Cancer Cell Growth Inhibition Evaluation of Novel Phosphatidylcholines with Anisic and Veratric Acids

scientific article published on 13 August 2018

Synthesis, anticancer and antibacterial activity of salinomycin N-benzyl amides.

scientific article published on 25 November 2014

Synthesis, antiproliferative activity and molecular docking of Colchicine derivatives.

scientific article published on 12 January 2016

Synthesis, antiproliferative activity and molecular docking of thiocolchicine urethanes

scientific article published on 12 September 2018

Synthesis, antiproliferative activity, and molecular docking studies of 4-chlorothiocolchicine analogues

scientific article published on 20 September 2019

Synthesis, antiproliferative and antibacterial activity of new amides of salinomycin.

scientific article published on 25 February 2014

Synthesis, antiproliferative and antibacterial evaluation of C-ring modified colchicine analogues.

scientific article

Synthesis, biological evaluation and molecular docking studies of new amides of 4-bromothiocolchicine as anticancer agents

scientific article published on 08 October 2019

Synthesis, biological evaluation and molecular docking studies of new amides of 4-chlorothiocolchicine as anticancer agents

scientific article published on 13 February 2020

Synthesis, crystal structure, 1H, 13C and 15N NMR studies, and biological evaluation of a new amidrazone-derived Au(III) complex

scientific article published in January 2019

Synthesis, cytotoxicity and antibacterial activity of new esters of polyether antibiotic - salinomycin.

scientific article published on 14 February 2014

Synthesis, molecular docking, ctDNA interaction, DFT calculation and evaluation of antiproliferative and anti-Toxoplasma gondii activities of 2,4-diaminotriazine-thiazole derivatives.

scientific article published on 6 February 2018

Synthesis, spectroscopical characterization and the biological activity in vitro of new platinum(II) complexes with imidazo[1,5-a]-1,3,5-triazine derivatives and dimethylsulfoxide

scientific article

Synthesis, structure and cytotoxic activity of new acetylenic derivatives of betulin.

scientific article published on 17 April 2013

Synthetic conjugates of genistein affecting proliferation and mitosis of cancer cells

scientific article published on 11 November 2010

Systematic coordination chemistry and cytotoxicity of copper(II) complexes with methyl substituted 4-nitropyridine N-oxides.

scientific article published on 11 May 2011

Tacalcitol increases the sensitivity of colorectal cancer cells to 5-fluorouracil by downregulating the thymidylate synthase

scientific article published on 25 March 2019

Temporal inhibition of mouse mammary gland cancer metastasis by CORM-A1 and DETA/NO combination therapy

scientific article published on 31 May 2019

The 5-hydrazino-3-methylisothiazole-4-carboxylic acid, its new 5-substituted derivatives and their antiproliferative activity

scientific article published on 22 June 2019

The Disulfide Analogues of Isophosphoramide Mustard for Anticancer Therapy

scientific article

The N'-Substituted Derivatives of 5-Chloro-3-Methylisothiazole-4-Carboxylic Acid Hydrazide with Antiproliferative Activity

scientific article published on 25 December 2019

The Toxicokinetic Profile of Dex40-GTMAC3-a Novel Polysaccharide Candidate for Reversal of Unfractionated Heparin

scientific article published on 17 March 2016

The antileukemic activity of modified fibrinogen-methotrexate conjugate.

scientific article published in March 2013

The antitumor effect of lowered doses of cytostatics combined with new analogs of vitamin D in mice.

scientific article published in September 2007

The antitumor effect of postoperative treatment with genistein alone or combined with cyclophosphamide in mice bearing transplantable tumors

scientific article published on 01 November 2000

The effect of bacteriophages T4 and HAP1 on in vitro melanoma migration.

scientific article

The effect of combined treatment on head and neck human cancer cell lines with novel analogs of calcitriol and cytostatics.

scientific article

The effect of the substitution level of some dextran-methotrexate conjugates on their antitumor activity in experimental cancer models.

scientific article published on May 2006

The effects of 1,4-dimethylpyridine in metastatic prostate cancer in mice

scientific article

The effects of staphylococcal bacteriophage lysates on cancer cells in vitro.

scientific article published on 25 September 2009

The halogenation of natural flavonoids, baicalein and chrysin, enhances their affinity to human protein kinase CK2

scientific article published on 04 May 2020

The in-vitro antiproliferative effect of PRI-2191 and imatinib applied in combined treatment with cisplatin, idarubicin, or docetaxel on human leukemia cells

scientific article published in January 2012

The influence of 1,25-dihydroxyvitamin D3 and 1,24-dihydroxyvitamin D3 on alphavbeta3 integrin expression in cancer cell lines

scientific article published on October 2008

The influence of a single and double biotinylation of xanthohumol on its anticancer activity

scientific article published on 01 December 2019

The role of GABA-ergic system in human mammary gland pathology and in growth of transplantable murine mammary cancer

scientific article published on 01 September 2000

The synthesis of 3,5,6,7-tetrasubstituted isoxazolo[4,5-b]pyridines and an evaluation of their in vitro antiproliferative activity

scientific article published on September 2012

The synthesis of indolo[2,3-b]quinoline derivatives with a guanidine group: highly selective cytotoxic agents

scientific article published on 20 October 2015

The tumorigenic potential of human CX-1 colon adenocarcinoma cells depends on carcinoembryonic antigen (CEACAM5) expression

scientific article published on 01 January 2003

Thiazole-based nitrogen mustards: Design, synthesis, spectroscopic studies, DFT calculation, molecular docking, and antiproliferative activity against selected human cancer cell lines

scientific article published in September 2016

Three-Component Reaction of Diamines with Triethyl Orthoformate and Diethyl Phosphite and Anti-Proliferative and Antiosteoporotic Activities of the Products

scientific article published on 20 March 2020

Thrombospondin-1 receptor mediates autophagy of RAS-expressing cancer cells and triggers tumour growth inhibition

scientific article

Toxicity and antineoplastic effect of (24R)-1,24-dihydroxyvitamin D3 (PRI-2191).

scientific article published in September 2004

Toxicity and antitumor activity of the vitamin D analogs PRI-1906 and PRI-1907 in combined treatment with cyclophosphamide in a mouse mammary cancer model

scientific article

Triazene salts: Design, synthesis, ctDNA interaction, lipophilicity determination, DFT calculation, and antiproliferative activity against human cancer cell lines

scientific article published on 22 November 2018

Unfavorable effect of calcitriol and its low-calcemic analogs on metastasis of 4T1 mouse mammary gland cancer

scientific article published on 2 November 2017

Uptake and bioreactivity of charged chitosan-coated superparamagnetic nanoparticles as promising contrast agents for magnetic resonance imaging.

scientific article published on 19 September 2017

Vitamin D Analogs Potentiate the Antitumor Effect of Imatinib Mesylate in a Human A549 Lung Tumor Model.

scientific article

Vitamin D Metabolite Profile in Cholecalciferol- or Calcitriol-Supplemented Healthy and Mammary Gland Tumor-Bearing Mice

scientific article published on 06 November 2020

Vitamin D analogs combined with 5-fluorouracil in human HT-29 colon cancer treatment.

scientific article

Vitamin D analogs enhance the anticancer activity of 5-fluorouracil in an in vivo mouse colon cancer model

scientific article

Vitamin D derivatives potentiate the anticancer and anti-angiogenic activity of tyrosine kinase inhibitors in combination with cytostatic drugs in an A549 non-small cell lung cancer model.

scientific article published on 15 December 2017

X-ray crystallographic, FT-IR and NMR studies as well as anticancer and antibacterial activity of the salt formed between ionophore antibiotic Lasalocid acid and amines

[The importance of angiogenesis in tumor growth dynamics]

scientific article published on 01 January 1998

[The influence of isoflavonoids on the antitumor activity of vitamin D3]

scientific article published on 01 January 2007

siRNA-mediated silencing of integrin β3 expression inhibits the metastatic potential of B16 melanoma cells

scientific article published on 10 August 2012

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