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List of works by Till Acker

A human post-mortem brain model for the standardization of multi-centre MRI studies.

scientific article

A woman with a rare p.Glu74Gly transthyretin mutation presenting exclusively with a rapidly progressive neuropathy: a case report

scientific article

Acidosis Acts through HSP90 in a PHD/VHL-Independent Manner to Promote HIF Function and Stem Cell Maintenance in Glioma.

scientific article published on 3 August 2016

An improved anatomical MRI technique with suppression of fixative fluid artifacts for the investigation of human postmortem brain phantoms

scientific article

Analysis of glomerular VEGF mRNA and protein expression in murine mesangioproliferative glomerulonephritis

scientific article

Angiopoietin 1 and 2 gene and protein expression is differentially regulated in acute anti-Thy1.1 glomerulonephritis

scientific journal article

Brain tumor stem cells

scientific article published on 01 January 2009

Cancer stem cells: a new framework for the design of tumor therapies.

scientific article published on 02 October 2010

Cell type specific expression of vascular endothelial growth factor and angiopoietin-1 and -2 suggests an important role of astrocytes in cerebellar vascularization

scientific article (publication date: October 2001)

Combined contrast-enhanced ultrasound and rt-PA treatment is safe and improves impaired microcirculation after reperfusion of middle cerebral artery occlusion

Continued response off treatment after BRAF inhibition in refractory hairy cell leukemia

scientific article

Cooperative interaction of hypoxia-inducible factor-2alpha (HIF-2alpha ) and Ets-1 in the transcriptional activation of vascular endothelial growth factor receptor-2 (Flk-1)

scientific journal article

DNA methylation-based classification of central nervous system tumours

scientific article published on 14 March 2018

Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration.

scientific article published in June 2001

Deregulated expression of TANK in glioblastomas triggers pro-tumorigenic ERK1/2 and AKT signaling pathways.

scientific article published on 11 November 2013

Development of progressive multifocal leukoencephalopathy in a patient with non-Hodgkin lymphoma 13 years after treatment with cladribine

scientific article published on 20 November 2012

Direct stimulation of adult neural stem cells in vitro and neurogenesis in vivo by vascular endothelial growth factor

scientific article published on 01 July 2004

EphrinB2 repression through ZEB2 mediates tumour invasion and anti-angiogenic resistance

scientific article published on 29 July 2016

Expression of Hypoxia-related Tissue Factors Correlates with Diminished Survival of Adjuvantly Treated Patients with Chromosome 1p Aberrant Oligodendroglial Neoplasms and Therapeutic Implications

scientific article published on 01 October 2004

Extracellular RNA liberates tumor necrosis factor-α to promote tumor cell trafficking and progression

scientific article published on 17 June 2013

Feedback regulators of hypoxia-inducible factors and their role in cancer biology.

scientific article published on 30 July 2010

Genetic evidence for a tumor suppressor role of HIF-2alpha.

scientific article published in August 2005

HG-68COMBINED ALTERATIONS IN MAPK PATHWAY GENES, CDKN2A/B AND ATRX CHARACTERIZE ANAPLASTIC PILOCYTIC ASTROCYTOMA.

scientific article published on 30 May 2016

High-mobility group AT-hook protein 2 expression and its prognostic significance in MGMT methylated and unmethylated glioblastoma.

scientific article

Hypoxia-inducible factor-1α activation in HPV-positive head and neck squamous cell carcinoma cell lines.

scientific article published on 11 September 2017

Implications of Oxygen Homeostasis for Tumor Biology and Treatment.

scientific article published on January 2016

Increased mitotic and proliferative activity are associated with worse prognosis in papillary tumors of the pineal region

scientific article published in January 2014

Infratentorial IDH-mutant astrocytoma is a distinct subtype

scientific article published on 10 August 2020

Integrating clinical decision support systems for pharmacogenomic testing into clinical routine - a scoping review of designs of user-system interactions in recent system development.

scientific article

Isolation and culture of primary glioblastoma cells from human tumor specimens.

scientific article published in January 2015

LGR5 is a marker of poor prognosis in glioblastoma and is required for survival of brain cancer stem-like cells

scientific article published on 30 August 2012

Loss of PHD3 allows tumours to overcome hypoxic growth inhibition and sustain proliferation through EGFR.

scientific article

Medical students on the move

scientific article published on 01 August 1996

Microvascularization and expression of VEGF and its receptors in recurring meningiomas: pathobiological data in favor of anti-angiogenic therapy approaches.

scientific article

Mutations in HID1 Cause Syndromic Infantile Encephalopathy and Hypopituitarism

scientific article published on 05 June 2021

NDRG2 and NDRG4 Expression Is Altered in Glioblastoma and Influences Survival in Patients with MGMT-methylated Tumors

scientific article published on March 2016

PHD3 regulates EGFR internalization and signalling in tumours.

scientific article

Protein kinase D2 is a novel regulator of glioblastoma growth and tumor formation.

scientific article published on July 2011

Quantification of muscle pathology in infantile Pompe disease.

scientific article

RESULTS OF THE INTERNATIONAL INTERLABORATORY COMPARISON OF MGMT PROMOTER METHYLATION ANALYSIS INVOLVING TWENTY-THREE ACADEMIC CENTERS IN GERMANY, AUSTRIA AND THE NETHERLANDS.

scientific article published in July 2014

Recurrent fusions in PLAGL1 define a distinct subset of pediatric-type supratentorial neuroepithelial tumors

scientific article published on 05 August 2021

Role of hypoxia in tumor angiogenesis-molecular and cellular angiogenic crosstalk.

scientific article

Spinocerebellar ataxia type 2 with glial cell cytoplasmic inclusions.

scientific article published on March 2004

Stress-induced upregulation of SLC19A3 is impaired in biotin-thiamine-responsive basal ganglia disease.

scientific article published on 29 January 2014

Supporting Molecular Tumor Boards in Molecular-Guided Decision-Making - The Current Status of Five German University Hospitals

scientific article published in January 2017

Synergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions.

scientific article published in May 2001

The cancer stem cell niche(s): The crosstalk between glioma stem cells and their microenvironment ⬇️

scientific article published on October 16, 2012

Tumors diagnosed as cerebellar glioblastoma comprise distinct molecular entities

scientific article published on 28 October 2019

Upregulation of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha in leptomeningeal vascular malformations of Sturge-Weber syndrome

scientific article published on 01 January 2007

Vascularization and expression of hypoxia-related tissue factors in intracranial ependymoma and their impact on patient survival

scientific article

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