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List of works by Ileana Soto

APOE Stabilization by Exercise Prevents Aging Neurovascular Dysfunction and Complement Induction.

scientific article published on 29 October 2015

Alteration of the serine protease PRSS56 causes angle-closure glaucoma in mice and posterior microphthalmia in humans and mice

scientific journal article

Changes in brain-derived neurotrophic factor and trkB receptor in the adult Rana pipiens retina and optic tectum after optic nerve injury.

scientific article published in December 2002

Changes in nNOS and NADPH diaphorase in frog retina and tectum after axotomy and FGF-2 application.

scientific article published on 30 June 2006

Chronic consumption of a western diet induces robust glial activation in aging mice and in a mouse model of Alzheimer's disease

scientific article published on 18 February 2016

Clustering of transcriptional profiles identifies changes to insulin signaling as an early event in a mouse model of Alzheimer's disease

scientific article

Combinatorial targeting of early pathways profoundly inhibits neurodegeneration in a mouse model of glaucoma

scientific article

DBA/2J mice are susceptible to diabetic nephropathy and diabetic exacerbation of IOP elevation.

scientific article

Deficiency of complement component 5 ameliorates glaucoma in DBA/2J mice.

scientific article published on 27 June 2013

Fibroblast growth factor 2 applied to the optic nerve after axotomy increases Bcl-2 and decreases Bax in ganglion cells by activating the extracellular signal-regulated kinase signaling pathway.

scientific article published in June 2005

Fibroblast growth factor 2 applied to the optic nerve after axotomy up-regulates BDNF and TrkB in ganglion cells by activating the ERK and PKA signaling pathways.

scientific article published on 3 November 2005

Glaucomatous optic nerve injury involves early astrocyte reactivity and late oligodendrocyte loss.

scientific article published in May 2010

Intrinsic axonal degeneration pathways are critical for glaucomatous damage.

scientific article published on 18 January 2012

Meox2 haploinsufficiency increases neuronal cell loss in a mouse model of Alzheimer's disease

scientific article published on 02 March 2016

Molecular clustering identifies complement and endothelin induction as early events in a mouse model of glaucoma

scientific article

NPC1 deficiency impairs cerebellar postnatal development of microglia and climbing fiber refinement in a mouse model of Niemann-Pick Type C disease

scientific article published on 01 July 2020

Radiation treatment inhibits monocyte entry into the optic nerve head and prevents neuronal damage in a mouse model of glaucoma

scientific article published on 19 March 2012

Reduced retina microglial activation and improved optic nerve integrity with minocycline treatment in the DBA/2J mouse model of glaucoma

scientific article published in April 2008

Retinal Ganglion Cell Loss in a Rat Ocular Hypertension Model Is Sectorial and Involves Early Optic Nerve Axon Loss ⬇️

scientific article published on January 21, 2011

Retinal ganglion cells downregulate gene expression and lose their axons within the optic nerve head in a mouse glaucoma model.

scientific article

Selective pattern of motor system damage in gamma-synuclein transgenic mice mirrors the respective pathology in amyotrophic lateral sclerosis

scientific article

The complex role of neuroinflammation in glaucoma

scientific article published on 03 July 2014

Under pressure: cellular and molecular responses during glaucoma, a common neurodegeneration with axonopathy

scientific article published on 12 April 2012

Up-regulation of brain-derived neurotrophic factor by application of fibroblast growth factor-2 to the cut optic nerve is important for long-term survival of retinal ganglion cells.

scientific article published on November 2008

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