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List of works by Ray K. Iles

Abnormal secretion of melatonin and cortisol in relation to sleep disturbances in children with Williams syndrome

scientific article published on 19 September 2014

Amplification or rearrangement of the beta-human chorionic gonadotrophin (beta-hCG)--human LH gene cluster is not responsible for the ectopic production of beta-hCG by bladder tumour cells

scientific article published on 01 March 1989

An introduction to mass spectrometry based proteomics-detection and characterization of gonadotropins and related molecules

scientific article

Arsenic trioxide induces cervical cancer apoptosis, but specifically targets human papillomavirus-infected cell populations.

scientific article published on March 2012

Capillary electrophoresis of human follicular fluid.

scientific article published on 22 October 2009

Clinical and endocrinological changes after electro-acupuncture treatment in patients with osteoarthritis of the knee.

scientific article published on 18 September 2009

Comparison of 12 assays for detecting hCG and related molecules in urine samples from Down syndrome pregnancies

scientific article published on 01 July 1997

Composition of intact hormone and free subunits in the human chorionic gonadotrophin-like material found in serum and urine of patients with carcinoma of the bladder

scientific article published on 01 September 1990

Concentrations of placental protein 14 in uterine flushings from infertile women: validation of the collection technique and method of expression of results.

scientific article published in December 1998

Cross-reaction with luteinizing hormone beta-core is responsible for the age-dependent increase of immunoreactive beta-core fragment of human chorionic gonadotropin in women with nonmalignant conditions

scientific article published on 01 April 1999

Designing a new generation of anti-hCG vaccines for cancer therapy

scientific article published on 17 October 2006

Detection of beta-core fragment in second trimester Down's syndrome pregnancies

scientific article published on 01 December 1996

Detection of human chorionic gonadotrophin-beta in serum or urine of prostate cancer patients is of no clinical significance

scientific article published on 27 April 2006

Determination of urinary cortisol, cortisone and 6-sulfatoxymelatonin using dilute and shoot ultra-high pressure liquid chromatography-tandem mass spectrometry

scientific article published on 3 December 2014

Differential proteolysis of insulin-like growth factor binding protein-1 (IGFBP-1) in pregnancy

scientific article published on 01 May 2013

Dimerization of urinary beta-core/hCFbetacf: a cause of poor beta-core assay performance in Down syndrome screening studies

scientific article published on 01 August 1999

Direct analysis of hCGβcf glycosylation in normal and aberrant pregnancy by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.

scientific article

Direct and rapid mass spectral fingerprinting of maternal urine for the detection of Down syndrome pregnancy

scientific article

Dissociation of human chorionic gonadotropin into its free subunits is dependent on naturally occurring molecular structural variation, sample matrix and storage conditions

scientific article published on 01 November 1998

Diurnal variation of urinary "hCG beta subunit core fragment" production evaluated in patients with gynecological neoplasms

scientific article published on 01 March 1994

Do not just do it, do it right: urinary metabolomics--establishing clinically relevant baselines

scientific article

Does hCG or hCGβ play a role in cancer cell biology?

scientific article published on 21 July 2010

Dramatic increase in levels of placental protein 14 in amniotic fluid at 10-15 weeks' pregnancy

scientific article published on 01 February 1994

Ectopic hCGbeta expression by epithelial cancer: malignant behaviour, metastasis and inhibition of tumor cell apoptosis.

scientific article published on 27 October 2006

Ectopic human chorionic gonadotropin beta secretion by epithelial tumors and human chorionic gonadotropin beta-induced apoptosis in Kaposi's sarcoma: is there a connection?

scientific article published on October 2003

Enhanced affinity capture MALDI-TOF MS: orientation of an immunoglobulin G using recombinant protein G.

scientific article

Enhancement of ectopic beta-human chorionic gonadotrophin expression by interferon-alpha

scientific article published on 01 December 1989

Estradiol, progesterone, testosterone profiles in human follicular fluid and cultured granulosa cells from luteinized pre-ovulatory follicles.

scientific article

Follicular fluid levels of inhibin A, inhibin B, and activin A levels reflect changes in follicle size but are not independent markers of the oocyte's ability to fertilize.

scientific article published on 2 May 2006

Gonadotropins and gonadotropin receptors--evolutional genetics, signalling mechanisms, extra gonadal function and roles in oncogenesis

scientific article published on 30 July 2010

Gonadotropins and prostate cancer: revisited.

scientific article published on January 2006

HILIC-MS-based shotgun metabolomic profiling of maternal urine at 9-23 weeks of gestation - establishing the baseline changes in the maternal metabolome

scientific article

High concentrations of CA 125 in uterine flushings: influence of cause of infertility and menstrual cycle day

scientific article published on 01 February 2002

Human Chorionic Gonadotropin (hCG) in the Secretome of Cultured Embryos: Hyperglycosylated hCG and hCG-Free Beta Subunit Are Potential Markers for Infertility Management and Treatment ⬇️

scientific article published on February 25, 2013

Human chorionic gonadotrophin and subunit composition of maternal serum and coelomic and amniotic fluids in the first trimester of pregnancy

scientific article published on December 1, 1992

Human chorionic gonadotropin isoforms in the diagnosis of ectopic pregnancy

scientific article published on 01 December 2003

Human granulosa-lutein cell in vitro production of progesterone, inhibin A, inhibin B, and activin A are dependent on follicular size and not the presence of the oocyte.

scientific article published on 6 August 2007

Human urothelial carcinomas—a typical disease of the aged: the clinical utility of human chorionic gonadotrophin in patient management and future therapy ⬇️

scientific article published on August 1, 1998

Identification of placental transforming growth factor-beta and bikunin metabolites as contaminants of pharmaceutical human chorionic gonadotrophin preparations by proteomic techniques.

scientific article

Immunochemical analysis of the human chorionic gonadotrophin-like material secreted by 'normal' and neoplastic urothelial cells

scientific article published on 01 March 1989

Immunoreactive beta-core-like material in normal postmenopausal urine: human chorionic gonadotrophin or LH origin? Evidence for the existence of LH core

scientific article published on 01 June 1992

In defense of science: investigation and evaluation without bias and prejudice.

scientific article published on 18 February 2010

Interference of Luteinizing Hormone beta-Core Fragment in Urinary Gonadotropin Assays

scientific article published on 01 December 1999

Low levels of amniotic fluid placental alkaline phosphatase in Down's syndrome

scientific article published on 01 September 1993

Low levels of amniotic fluid pregnancy specific beta-1-glycoprotein in Down's syndrome

scientific article published on 01 June 1994

Low serum levels of placental and placental-like alkaline phosphatase isoenzymes in women with blood groups A and AB

scientific article published on 01 January 1994

Maternal serum human chorionic gonadotrophin and pregnancy-associated plasma protein A, markers for fetal Down syndrome at 8-14 weeks

scientific article published on 01 March 1994

Measures of urine concentration in maternal urine screening for Down syndrome

scientific article published on 01 October 1998

Novel insights into the expression of CGB1 & 2 genes by epithelial cancer cell lines secreting ectopic free hCGβ.

scientific article published on May 2014

Pregnancy-associated plasma protein A levels in maternal serum, extraembryonic coelomic and amniotic fluids in the first trimester

scientific article published on 01 October 1994

Prognostic significance of the bcl-2 apoptotic family of proteins in primary and recurrent cervical cancer

scientific article

Purification and assay of insulin-like growth factor-binding protein-1: measurement of circulating levels throughout pregnancy

scientific article published on 01 January 1991

Purine metabolite levels in preovulatory human follicles may hold the key to ovarian hyperstimulation syndrome.

scientific article published on 24 May 2010

Rapid diagnosis of testicular choriocarcinoma by urinary pregnancy tests

scientific article published in The Lancet

Second trimester amniotic fluid placental alkaline phosphatase levels are low in Down's syndrome but not in other fetal abnormalities

scientific article published on 01 April 1994

Secretome profile selection of optimal IVF embryos by matrix-assisted laser desorption ionization time-of-flight mass spectrometry

scientific article published on 15 May 2019

Serum PAPP-A measurements in first-trimester screening for Down syndrome

scientific article published on 01 October 1993

Serum concentrations of cancer antigen 125, placental alkaline phosphatase, cancer-associated serum antigen and free beta human chorionic gonadotrophin as prognostic markers for epithelial ovarian cancer

scientific article published on 01 September 1997

Serum placental-type alkaline phosphatase activity in women with squamous and glandular malignancies of the reproductive tract.

scientific article

Serum placental-type alkaline-phosphatase levels in patients with epithelial ovarian-carcinoma

scientific article published on 01 February 1995

Single point biochemical measurement algorithm for early diagnosis of ectopic pregnancy

scientific article

Stable knockdown of hCGβ mRNA expression in bladder cancer cells results in significant growth inhibition

scientific article published on September 2013

Substantial urinary concentrations of material resembling beta-core fragment of chorionic gonadotropin beta-subunit in mid-menstrual cycle

scientific article published on 01 September 1993

The Diagnosis of Sulfated Hemoglobin (SulfHb) Secondary to Sulfur Dioxide Poisoning Using Matrix-Assisted Laser Desorption Time-of-Flight Mass Spectrometry (MALDI-ToF MS)-A Novel Approach to an Unusual Clinical Problem

scientific article published on 10 February 2020

The beta-subunit of human chorionic gonadotrophin exists as a homodimer.

scientific article

The effect of smoking on serum placental alkaline phosphatase levels in pregnancy

scientific article published on 01 October 1993

The effects of 'coasting' on follicular fluid concentrations of vascular endothelial growth factor in women at risk of developing ovarian hyperstimulation syndrome.

scientific article published on 29 January 2004

The free monomeric beta subunit of human chorionic gonadotrophin (hCG beta) and the recently identified homodimeric beta-beta subunit (hCG beta beta) both have autocrine growth effects.

scientific article

The increase in bladder carcinoma cell population induced by the free beta subunit of human chorionic gonadotrophin is a result of an anti-apoptosis effect and not cell proliferation.

scientific article

The measurement of urinary beta core fragment in conjunction with serum CA125 does not aid the differentiation of malignant from benign pelvic masses

scientific article published on 01 December 1993

The prognostic significance of beta human chorionic gonadotrophin and its metabolites in women with cervical carcinoma

scientific article published on September 1998

The prognostic significance of urinary beta core fragment in premenopausal women with carcinoma of the cervix

scientific article published on 01 November 1994

The purification and development of a radioimmunoassay for beta-core fragment of human chorionic gonadotrophin in urine: application as a marker of gynaecological cancer in premenopausal and postmenopausal women

scientific article published on 01 September 1991

The role of glycosylation in regulating the glycoprotein hormone free alpha-subunit and free beta-subunit combination in the extraembryonic coelomic fluid of early pregnancy

scientific article published on 01 March 1995

The temporary anatomical structures prominent in the first trimester may be fulfilling exchange functions assigned to the placenta in the second and third trimester.

scientific article published on June 1996

Towards the development of an electrochemical biosensor for hCGbeta detection.

scientific article published on 10 June 2008

Urinary analysis for Down's syndrome: is the measurement of urinary beta-core the future of biochemical screening for Down's syndrome.

scientific article

Urinary beta-core hCG: screening for aneuploidies in early pregnancy (11-14 weeks' gestation)

scientific article published on 01 May 1997

Urinary beta-core human chorionic gonadotrophin: a new approach to Down's syndrome screening.

scientific article published in October 1994

Urinary chorionic gonadotropin subunits and beta-core in nonpregnant women. A study of benign and malignant gynecologic disorders

scientific article published on 01 June 1993

Urinary concentration of human chorionic gonadotrophin and its fragments as a prognostic marker in bladder cancer

scientific article published on 01 January 1996

β-hCG expression by bladder cancers ⬇️

scientific article published on February 1, 1992

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