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List of works by Emma Bolderson

ATM is required for the cellular response to thymidine induced replication fork stress.

scientific article

ATM-dependent phosphorylation of MRE11 controls extent of resection during homology directed repair by signalling through Exonuclease 1.

scientific article published on 3 August 2015

Activation and cleavage of SASH1 by caspase-3 mediates an apoptotic response

scientific article published on 10 November 2016

Barrier-to-autointegration factor 1 (Banf1) regulates poly [ADP-ribose] polymerase 1 (PARP1) activity following oxidative DNA damage

scientific article published on 03 December 2019

Chemotherapeutic compounds targeting the DNA double-strand break repair pathways: the good, the bad, and the promising

scientific article

Elevating CDCA3 levels in non-small cell lung cancer enhances sensitivity to platinum-based chemotherapy

scientific article published on 28 May 2021

Exo1 plays a major role in DNA end resection in humans and influences double-strand break repair and damage signaling decisions

scientific article published on 11 February 2012

HSSB1 and hSSB2 form similar multiprotein complexes that participate in DNA damage response

scientific article

Human single-stranded DNA binding protein 1 (hSSB1/NABP2) is required for the stability and repair of stalled replication forks.

scientific article

Human single-stranded DNA binding proteins are essential for maintaining genomic stability

scientific article

INTS3 controls the hSSB1-mediated DNA damage response

scientific article published on 28 September 2009

Involvement of Exo1b in DNA damage-induced apoptosis

scientific article published on April 2009

Kruppel-associated Box (KRAB)-associated co-repressor (KAP-1) Ser-473 phosphorylation regulates heterochromatin protein 1β (HP1-β) mobilization and DNA repair in heterochromatin

scientific article

Multiple human single-stranded DNA binding proteins function in genome maintenance: structural, biochemical and functional analysis

scientific article

Nucleophosmin: from structure and function to disease development

scientific article

Néstor-Guillermo Progeria Syndrome: a biochemical insight into Barrier-to-Autointegration Factor 1, alanine 12 threonine mutation

scientific article published on 12 December 2014

Phosphorylation of Exo1 modulates homologous recombination repair of DNA double-strand breaks

scientific article

Rad51 supports triple negative breast cancer metastasis

scientific article published in May 2014

Recent advances in cancer therapy targeting proteins involved in DNA double-strand break repair.

scientific article

SASH1 mediates sensitivity of breast cancer cells to chloropyramine and is associated with prognosis in breast cancer.

scientific article published on 14 September 2016

SECIS-binding protein 2 promotes cell survival by protecting against oxidative stress.

scientific article published on April 2010

Single-stranded DNA-binding protein hSSB1 is critical for genomic stability

scientific article

hSSB1 (NABP2/ OBFC2B) is required for the repair of 8-oxo-guanine by the hOGG1-mediated base excision repair pathway.

scientific article published on 10 August 2015

hSSB1 (NABP2/OBFC2B) is regulated by oxidative stress

scientific article published on 8 June 2016

hSSB1 associates with and promotes stability of the BLM helicase

scientific article

hSSB1 interacts directly with the MRN complex stimulating its recruitment to DNA double-strand breaks and its endo-nuclease activity

scientific article

hSSB1 phosphorylation is dynamically regulated by DNA-PK and PPP-family protein phosphatases

scientific article published on 6 April 2017

hSSB1 rapidly binds at the sites of DNA double-strand breaks and is required for the efficient recruitment of the MRN complex

scientific article

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